公开(公告)号：US20160230157A1

公开(公告)日：2016-08-11

申请号：US15139050

申请日：2016-04-26

Applicant: NOVOZYMES A/S

Inventor： Esben Peter Friis ,  Leonardo De Maria ,  Jesper Vind ,  Thomas A. Poulsen ,  Allan Svendsen ,  Steffen Danielsen ,  Rolf T. Lenhard ,  Henrik Friis-Madsen ,  Lars K. Skov

IPC: C12N9/34 ,  C12P5/02 ,  C12P7/54 ,  C12P13/20 ,  C12P37/00 ,  C12P7/06

CPC classification number: C12N9/2428 ,  C12N9/242 ,  C12P5/002 ,  C12P5/02 ,  C12P7/06 ,  C12P7/46 ,  C12P7/48 ,  C12P7/54 ,  C12P7/56 ,  C12P13/20 ,  C12P19/20 ,  C12P37/00 ,  C12Y302/01001 ,  C12Y302/01003 ,  Y02E50/17

Abstract: The present invention relates to glucoamylase variants having improved thermostability. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

Abstract translation: 本发明涉及具有改善的热稳定性的葡糖淀粉酶变体。 本发明还涉及编码这些变体的多核苷酸; 核酸构建体，载体和包含多核苷酸的宿主细胞; 以及使用这些变体的方法。

公开(公告)号：US08853381B2

公开(公告)日：2014-10-07

申请号：US13968958

申请日：2013-08-16

Applicant: Novozymes A/S

Inventor： Tomoko Matsui ,  Henriette Draborg ,  Steffen Danielsen

IPC: C12N15/63 ,  C07H21/04 ,  C07K14/37 ,  C12N9/64 ,  C12N9/42 ,  C12N15/62 ,  C12N9/16 ,  C12P21/06

CPC classification number: C12N9/6472 ,  C07K14/37 ,  C12N9/16 ,  C12N9/2437 ,  C12N9/6424 ,  C12N15/625

Abstract: The present invention relates to a method for producing a polypeptide comprising using a signal peptide, to nucleic acid constructs comprising a first nucleotide sequence encoding the signal peptide and a second nucleotide sequence encoding a polypeptide which is foreign to the first nucleotide sequence. Furthermore, it also relates to expression vectors and host cells comprising the nuclei acid construct.

Abstract translation: 本发明涉及包含使用信号肽的多肽的制备方法，其包含编码信号肽的第一核苷酸序列的核酸构建体和编码第一核苷酸序列异源的多肽的第二核苷酸序列。 此外，它还涉及包含核酸构建体的表达载体和宿主细胞。

公开(公告)号：US20140255997A1

公开(公告)日：2014-09-11

申请号：US14351469

申请日：2012-10-11

Applicant: NOVOZYMES A/S

Inventor： Esben Peter Friis ,  Leonardo De Maria ,  Jesper Vind ,  Thomas A. Poulsen ,  Allan Svendsen ,  Steffen Danielsen ,  Rolf T. Lenhard ,  Henrik Friis-Madsen ,  Lars K. Skov

IPC: C12N9/34 ,  C12P19/20

CPC classification number: C12N9/2428 ,  C12N9/242 ,  C12P5/002 ,  C12P5/02 ,  C12P7/06 ,  C12P7/46 ,  C12P7/48 ,  C12P7/54 ,  C12P7/56 ,  C12P13/20 ,  C12P19/20 ,  C12P37/00 ,  C12Y302/01001 ,  C12Y302/01003 ,  Y02E50/17

Abstract: The present invention relates to glucoamylase variants having improved thermostability. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

Abstract translation: 本发明涉及具有改善的热稳定性的葡糖淀粉酶变体。 本发明还涉及编码这些变体的多核苷酸; 核酸构建体，载体和包含多核苷酸的宿主细胞; 以及使用这些变体的方法。

公开(公告)号：US20190106689A1

公开(公告)日：2019-04-11

申请号：US16225168

申请日：2018-12-19

Applicant: Novozymes A/S

Inventor： Steffen Danielsen ,  Peter Kamp Hansen ,  Frank Winther Rasmussen ,  Roland Alexander Pache

IPC: C12N9/24 ,  C12Q1/68 ,  C12N15/87 ,  C12N5/04 ,  C07H21/04

Abstract: The present invention relates to xylanase variants, polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; compositions comprising the xylanase variants and methods of using the variants.

公开(公告)号：US20190002856A1

公开(公告)日：2019-01-03

申请号：US16135407

申请日：2018-09-19

Applicant: NOVOZYMES A/S

Inventor： Esben Peter Friis ,  Leonardo De Maria ,  Jesper Vind ,  Thomas A. Poulsen ,  Allan Svendsen ,  Steffen Danielsen ,  Rolf T. Lenhard ,  Henrik Friis-Madsen ,  Lars K. Skov

IPC: C12N9/34 ,  C12N9/30 ,  C12P5/00 ,  C12P7/46 ,  C12P7/48 ,  C12P37/00 ,  C12P13/20 ,  C12P7/54 ,  C12P7/06 ,  C12P5/02 ,  C12P19/20 ,  C12P7/56

Abstract: The present invention relates to glucoamylase variants having improved thermostability. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

公开(公告)号：US09540624B2

公开(公告)日：2017-01-10

申请号：US15139050

申请日：2016-04-26

Applicant: NOVOZYMES A/S

Inventor： Esben Peter Friis ,  Leonardo De Maria ,  Jesper Vind ,  Thomas A. Poulsen ,  Allan Svendsen ,  Steffen Danielsen ,  Rolf T. Lenhard ,  Henrik Friis-Madsen ,  Lars K. Skov

IPC: C12N9/24 ,  C12N9/34 ,  C12P19/20 ,  C12P5/02 ,  C12P7/06 ,  C12P7/54 ,  C12P13/20 ,  C12P37/00

CPC classification number: C12N9/2428 ,  C12N9/242 ,  C12P5/002 ,  C12P5/02 ,  C12P7/06 ,  C12P7/46 ,  C12P7/48 ,  C12P7/54 ,  C12P7/56 ,  C12P13/20 ,  C12P19/20 ,  C12P37/00 ,  C12Y302/01001 ,  C12Y302/01003 ,  Y02E50/17

Abstract: The present invention relates to glucoamylase variants having improved thermostability. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

Abstract translation: 本发明涉及具有改善的热稳定性的葡糖淀粉酶变体。 本发明还涉及编码这些变体的多核苷酸; 核酸构建体，载体和包含多核苷酸的宿主细胞; 以及使用这些变体的方法。

公开(公告)号：US09353362B2

公开(公告)日：2016-05-31

申请号：US14351469

申请日：2012-10-11

Applicant: NOVOZYMES A/S

Inventor： Esben Peter Friis ,  Leonardo De Maria ,  Jesper Vind ,  Thomas A. Poulsen ,  Allan Svendsen ,  Steffen Danielsen ,  Rolf T. Lenhard ,  Henrik Friis-Madsen ,  Lars K. Skov

IPC: C12N9/24 ,  C12N9/34 ,  C12P19/20

CPC classification number: C12N9/2428 ,  C12N9/242 ,  C12P5/002 ,  C12P5/02 ,  C12P7/06 ,  C12P7/46 ,  C12P7/48 ,  C12P7/54 ,  C12P7/56 ,  C12P13/20 ,  C12P19/20 ,  C12P37/00 ,  C12Y302/01001 ,  C12Y302/01003 ,  Y02E50/17

Abstract: The present invention relates to glucoamylase variants having improved thermostability. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

Abstract translation: 本发明涉及具有改善的热稳定性的葡糖淀粉酶变体。 本发明还涉及编码这些变体的多核苷酸; 核酸构建体，载体和包含多核苷酸的宿主细胞; 以及使用这些变体的方法。

公开(公告)号：US20150152397A1

公开(公告)日：2015-06-04

申请号：US14403949

申请日：2013-05-30

Applicant: NOVOZYMES A/S

Inventor： Bjarne Gram Hansen ,  Steffen Danielsen ,  Lars Kobberoee Skov ,  Leonardo De Maria ,  Julie Bille Rannes

IPC: C12N9/16 ,  A62D3/30

CPC classification number: C12N9/16 ,  A62D3/02 ,  A62D3/30 ,  A62D2101/02 ,  A62D2101/04 ,  A62D2101/26 ,  C12Y301/08002

Abstract: The present invention relates to isolated polypeptides having organophosphorous hydrolase activity, and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.

Abstract translation: 本发明涉及具有有机磷水解酶活性的分离的多肽和编码多肽的多核苷酸。 本发明还涉及包含多核苷酸的核酸构建体，载体和宿主细胞以及产生和使用多肽的方法。

公开(公告)号：US20140193879A1

公开(公告)日：2014-07-10

申请号：US14209463

申请日：2014-03-13

Applicant: Novozymes A/S

Inventor： Steffen Danielsen ,  Lars Kobberoee Skov ,  Ricardo Leite ,  Vincent Laize ,  M. Leonor Cancela Da Fonseca

IPC: C12N9/16

CPC classification number: C12N9/16 ,  A62D3/02 ,  A62D2101/02 ,  A62D2101/04 ,  A62D2101/26 ,  C12Y301/08001 ,  C12Y301/08002

Abstract: The present invention relates to isolated polypeptides having organophosphorous hydrolase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.

Abstract translation: 本发明涉及具有有机磷水解酶活性的分离的多肽和编码多肽的分离的多核苷酸。 本发明还涉及包含多核苷酸的核酸构建体，载体和宿主细胞以及产生和使用多肽的方法。