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公开(公告)号：US20190233863A1
公开(公告)日：2019-08-01
申请号：US16377037
申请日：2019-04-05
申请人： XYLECO, INC.
IPC分类号： C12P19/14 , C12P19/04 , C12N9/42 , C12P19/12 , C12P7/10 , C12P5/02 , C12P7/04 , C12P7/16 , C12P7/24 , C12P7/28 , C12P7/40 , C12P7/42 , C12P7/46 , C12P7/48 , C12P7/52 , C12P7/56 , C12P7/62 , C12P19/02
CPC分类号： C12P19/14 , C12N9/2434 , C12N9/2437 , C12P5/02 , C12P5/023 , C12P7/04 , C12P7/10 , C12P7/16 , C12P7/24 , C12P7/28 , C12P7/40 , C12P7/42 , C12P7/46 , C12P7/48 , C12P7/52 , C12P7/56 , C12P7/62 , C12P19/02 , C12P19/04 , C12P19/12 , C12P2201/00 , C12Y302/01004 , Y02E50/16 , Y02E50/17 , Y02E50/343
摘要： Provided herein are methods for processing biomass materials that are disposed in one or more structures or carriers, e.g., a bag, a shell, a net, a membrane, a mesh or any combination of these. Containing the material in this manner allows it to be readily added or removed at any point and in any sequence during processing.
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2.发明申请公开(公告)号：US20190194029A1
公开(公告)日：2019-06-27
申请号：US16068989
申请日：2017-01-19
申请人： PURAC BIOCHEM BV
IPC分类号： C01F5/30 , C01F5/10 , C01B7/03 , B01D1/26 , B01D1/28 , C12P7/52 , C07C51/02 , C12P7/48 , C12P7/44 , C12P7/40 , C12P7/56 , C12P17/04 , C12P7/42 , C12P7/46
CPC分类号： C01F5/30 , B01D1/26 , B01D1/28 , C01B7/035 , C01F5/10 , C07C51/02 , C12P7/40 , C12P7/42 , C12P7/44 , C12P7/46 , C12P7/48 , C12P7/52 , C12P7/56 , C12P17/04 , C07C55/10 , C07C59/08 , C07C59/06 , C07C59/01
摘要： Magnesium chloride solutions including providing aqueous magnesium chloride solution with magnesium chloride concentration of 10-30 wt. % to concentration step where water is evaporated, resulting in concentrated magnesium chloride solution with magnesium chloride concentration of 30-50 wt. %, wherein concentration step is carried out in one or more stages, wherein at least one of the stages is conducted at elevated pressure, withdrawing concentrated magnesium chloride solution from concentration step, and providing it to thermohydrolysis reactor of at least 300° C., withdrawing MgO from thermohydrolysis reactor in solid form, and withdrawing a HCl containing gas stream of at least 300° C. from thermohydrolysis reactor, providing the HCl-containing gas stream of at least 300° C. to cooling step, where HCl-containing gas stream is contacted with cooling liquid, withdrawing HCl-containing gas stream below 150° C. from cooling step, circulating cooling liquid through heat exchanger where energy is transferred to heating liquid which circulates from heat exchanger to concentration step.
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公开(公告)号：US10053684B2
公开(公告)日：2018-08-21
申请号：US14745202
申请日：2015-06-19
IPC分类号： C12N9/92 , C12P7/16 , C12P7/56 , C12P7/42 , C12P7/10 , C12N9/90 , C12P17/18 , C12P35/06 , C12P7/06 , C12P7/18 , C12P7/20 , C12P7/40 , C12P7/64 , C12P13/04 , C12P5/02 , C12P7/46 , C12P7/48 , C12P7/54 , C12P13/02
CPC分类号： C12N9/92 , C12N9/90 , C12P5/026 , C12P7/06 , C12P7/10 , C12P7/16 , C12P7/18 , C12P7/20 , C12P7/40 , C12P7/42 , C12P7/46 , C12P7/48 , C12P7/54 , C12P7/56 , C12P7/649 , C12P13/02 , C12P13/04 , C12P17/184 , C12P35/06 , C12P2203/00 , C12Y503/01005 , Y02E50/10 , Y02E50/13 , Y02E50/16 , Y02E50/17 , Y02E50/343
摘要： This disclosure relates to novel xylose isomerases and their uses, particularly in fermentation processes that employ xylose-containing media.
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公开(公告)号：US09963730B2
公开(公告)日：2018-05-08
申请号：US15596658
申请日：2017-05-16
申请人： XYLECO, INC.
IPC分类号： C12P19/14 , C12P7/10 , C12N9/42 , C12P5/02 , C12P7/04 , C12P7/16 , C12P7/24 , C12P7/28 , C12P7/40 , C12P7/42 , C12P7/46 , C12P7/48 , C12P7/52 , C12P7/56 , C12P7/62 , C12P19/02 , C12P19/04 , C12P19/12
CPC分类号： C12P19/14 , C12N9/2434 , C12N9/2437 , C12P5/02 , C12P5/023 , C12P7/04 , C12P7/10 , C12P7/16 , C12P7/24 , C12P7/28 , C12P7/40 , C12P7/42 , C12P7/46 , C12P7/48 , C12P7/52 , C12P7/56 , C12P7/62 , C12P19/02 , C12P19/04 , C12P19/12 , C12P2201/00 , C12Y302/01004 , Y02E50/16 , Y02E50/17 , Y02E50/343
摘要： Provided herein are methods for processing biomass materials that are disposed in one or more structures or carriers, e.g., a bag, a shell, a net, a membrane, a mesh or any combination of these. Containing the material in this manner allows it to be readily added or removed at any point and in any sequence during processing.
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公开(公告)号：US20180066296A9
公开(公告)日：2018-03-08
申请号：US15368092
申请日：2016-12-02
CPC分类号： C12P19/32 , C08G69/02 , C12N9/0008 , C12N9/1029 , C12N9/1096 , C12N9/13 , C12P7/18 , C12P7/42 , C12P7/48 , C12P11/00 , C12P13/00 , C12P13/001 , C12P21/00 , C12Y102/99006 , C12Y203/01 , C12Y203/01016 , C12Y203/01041 , C12Y203/01174 , C12Y203/01179 , C12Y203/0118 , C12Y206/01018 , C12Y208/03
摘要： This document describes biochemical pathways for producing 7-aminoheptanoic acid using a β-ketoacyl synthase or a β-ketothiolase to form an N-acetyl-5-amino-3-oxopentanoyl-CoA intermediate. 7-aminoheptanoic acid can be enzymatically converted to pimelic acid, 7-hydroxyheptanoic acid, heptamethylenediamine or 1,7-heptanediol or corresponding salts thereof. This document also describes recombinant microorganisms producing 7-aminoheptanoic acid as well as pimelic acid, 7-hydroxyheptanoic acid, heptamethylenediamine and 1,7-heptanediol or corresponding salts thereof.
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公开(公告)号：US09701972B2
公开(公告)日：2017-07-11
申请号：US14236191
申请日：2012-08-02
IPC分类号： C12N15/81 , C12N9/92 , C12P7/10 , C12P7/16 , C12P7/18 , C12P7/20 , C12P7/40 , C12P7/42 , C12P7/46 , C12P7/48 , C12P7/54 , C12P7/56 , C12P5/02 , C12P7/06 , C12P35/00
CPC分类号： C12N15/81 , C12N9/92 , C12N15/815 , C12P5/026 , C12P7/06 , C12P7/10 , C12P7/16 , C12P7/18 , C12P7/20 , C12P7/40 , C12P7/42 , C12P7/46 , C12P7/48 , C12P7/54 , C12P7/56 , C12P35/00 , C12Y503/01005 , Y02E50/16 , Y02E50/17
摘要： The invention relates to a cell which comprises a nucleotide sequence encoding a xylose isomerase, wherein the amino acid sequence of the xylose isomerase has at least 75% sequence identity to the amino acid sequence set out in SEQ ID NO: 2 and wherein the nucleotide sequence is heterologous to the host. A cell of the invention may be used in a process for producing a fermentation product, such as ethanol. Such a process may comprise fermenting a medium containing a source of xylose with a cell of the invention such that the cell ferments xylose to the fermentation product.
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公开(公告)号：US20170159092A1
公开(公告)日：2017-06-08
申请号：US15368092
申请日：2016-12-02
CPC分类号： C12P19/32 , C08G69/02 , C12N9/0008 , C12N9/1029 , C12N9/1096 , C12N9/13 , C12P7/18 , C12P7/42 , C12P7/48 , C12P11/00 , C12P13/00 , C12P13/001 , C12P21/00 , C12Y102/99006 , C12Y203/01 , C12Y203/01016 , C12Y203/01041 , C12Y203/01174 , C12Y203/01179 , C12Y203/0118 , C12Y206/01018 , C12Y208/03
摘要： This document describes biochemical pathways for producing 7-aminoheptanoic acid using a β-ketoacyl synthase or a β-ketothiolase to form an N-acetyl-5-amino-3-oxopentanoyl-CoA intermediate. 7-aminoheptanoic acid can be enzymatically converted to pimelic acid, 7-hydroxyheptanoic acid, heptamethylenediamine or 1,7-heptanediol or corresponding salts thereof. This document also describes recombinant microorganisms producing 7-aminoheptanoic acid as well as pimelic acid, 7-hydroxyheptanoic acid, heptamethylenediamine and 1,7-heptanediol or corresponding salts thereof.
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公开(公告)号：US09540624B2
公开(公告)日：2017-01-10
申请号：US15139050
申请日：2016-04-26
申请人： NOVOZYMES A/S
发明人： Esben Peter Friis , Leonardo De Maria , Jesper Vind , Thomas A. Poulsen , Allan Svendsen , Steffen Danielsen , Rolf T. Lenhard , Henrik Friis-Madsen , Lars K. Skov
CPC分类号： C12N9/2428 , C12N9/242 , C12P5/002 , C12P5/02 , C12P7/06 , C12P7/46 , C12P7/48 , C12P7/54 , C12P7/56 , C12P13/20 , C12P19/20 , C12P37/00 , C12Y302/01001 , C12Y302/01003 , Y02E50/17
摘要： The present invention relates to glucoamylase variants having improved thermostability. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
摘要翻译： 本发明涉及具有改善的热稳定性的葡糖淀粉酶变体。 本发明还涉及编码这些变体的多核苷酸; 核酸构建体，载体和包含多核苷酸的宿主细胞; 以及使用这些变体的方法。
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公开(公告)号：US09353362B2
公开(公告)日：2016-05-31
申请号：US14351469
申请日：2012-10-11
申请人： NOVOZYMES A/S
发明人： Esben Peter Friis , Leonardo De Maria , Jesper Vind , Thomas A. Poulsen , Allan Svendsen , Steffen Danielsen , Rolf T. Lenhard , Henrik Friis-Madsen , Lars K. Skov
CPC分类号： C12N9/2428 , C12N9/242 , C12P5/002 , C12P5/02 , C12P7/06 , C12P7/46 , C12P7/48 , C12P7/54 , C12P7/56 , C12P13/20 , C12P19/20 , C12P37/00 , C12Y302/01001 , C12Y302/01003 , Y02E50/17
摘要： The present invention relates to glucoamylase variants having improved thermostability. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
摘要翻译： 本发明涉及具有改善的热稳定性的葡糖淀粉酶变体。 本发明还涉及编码这些变体的多核苷酸; 核酸构建体，载体和包含多核苷酸的宿主细胞; 以及使用这些变体的方法。
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10.发明申请ENHANCED ITACONIC ACID PRODUCTION IN ASPERGILLUS WITH INCREASED LAEA EXPRESSION 有权在增加的LAEA表达中增强了ASPERGILLUS中的ITACONIC酸生产公开(公告)号：US20160046967A1
公开(公告)日：2016-02-18
申请号：US14928511
申请日：2015-10-30
发明人： Ziyu Dai , Scott E. Baker
CPC分类号： C12P7/44 , C07K14/38 , C12N1/14 , C12N9/1051 , C12P7/48 , C12Y204/01258
摘要： Fungi, such as Aspergillus niger, having a dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase (Alg3) gene genetic inactivation, increased expression of a loss of aflR expression A (LaeA), or both, are described. In some examples, such mutants have several phenotypes, including an increased production of citric acid relative to the parental strain. Methods of using the disclosed fungi to make citric acid are also described, as are compositions and kits including the disclosed fungi. Further described are Aspergillus terreus fungi overexpressing the LaeA gene and the use of such fungi for the production of itaconic acid.
摘要翻译： 真菌，如黑曲霉，具有双酰基-P-Man：Man（5）GlcNAc（2）-PP-二酰基甘露糖基转移酶（Alg3）基因失活，增加了aflR表达A（LaeA）或两者的丧失表达 ，被描述。 在一些实例中，这样的突变体具有几种表型，包括相对于亲本菌株增加柠檬酸的产生。 还描述了使用所公开的真菌制备柠檬酸的方法，以及包括所公开的真菌的组合物和试剂盒。 进一步描述了过表达LaeA基因的土曲霉菌和使用这种真菌生产衣康酸。
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