公开(公告)号：US20180214238A1

公开(公告)日：2018-08-02

申请号：US15882790

申请日：2018-01-29

Applicant: Novartis AG

Inventor： Cesario Dos Santos ,  Gerald David Bacher ,  Ronald Smith ,  Alireza Mirsepassi ,  Michael Papac

IPC: A61B90/30 ,  A61F9/007 ,  A61B17/02

Abstract: Focusing optics for mode mixing may be used to homogenize different modes in an optical fiber used for surgical illumination. A vibration stage may impart mechanical motion to a condenser lens to generate a homogeneous illumination field from a coherent light source.

公开(公告)号：US20180214018A1

公开(公告)日：2018-08-02

申请号：US15882867

申请日：2018-01-29

Applicant: Novartis AG

Inventor： Cesario Dos Santos ,  Gerald David Bacher ,  Ronald Smith ,  Alireza Mirsepassi ,  Michael Papac

IPC: A61B3/00 ,  A61B1/07

CPC classification number: A61B3/0008 ,  A61B1/07 ,  A61B90/30 ,  A61B2090/306 ,  G02B23/2469 ,  G02B26/06 ,  G02B26/0833

Abstract: Pixelated array optics for mode mixing may be used to homogenize different modes in an optical fiber used for surgical illumination. A pixelated phase array, such as a digital micromirror device or an LCD phase plate, may impart motion to an incident beam entering the optical fiber to generate a homogeneous illumination field from a coherent light source.

公开(公告)号：US09693686B2

公开(公告)日：2017-07-04

申请号：US15043064

申请日：2016-02-12

Applicant: NOVARTIS AG

Inventor： Ronald T. Smith ,  Lingfeng Yu ,  Michael Papac ,  Argelio Michael Olivera ,  Steven T. Charles

IPC: A61B3/14 ,  A61B3/10 ,  A61B3/13 ,  A61B3/12 ,  A61B3/00 ,  A61B3/125 ,  G02B27/00

CPC classification number: A61B3/13 ,  A61B3/0025 ,  A61B3/1015 ,  A61B3/12 ,  A61B3/125 ,  G02B27/0068

Abstract: Systems, apparatuses, and methods of and for an ophthalmic visualization system are disclosed. An example ophthalmic visualization system may include a first lens positioned relative to a surgical microscope in a manner facilitating viewing of a central region of a retina through the surgical microscope during a surgical procedure. The first lens may be positionable in an optical path between an eye and the surgical microscope during the surgical procedure. The example ophthalmic visualization system may also include a second lens selectively positionable relative to the surgical microscope and the first lens in a manner facilitating viewing of a peripheral region of the retina of the eye during the surgical procedure. The second lens may be selectively positionable in the optical path such that the peripheral region is selectively viewable without changing the position of the first lens during the surgical procedure.

公开(公告)号：US20160270649A1

公开(公告)日：2016-09-22

申请号：US15168946

申请日：2016-05-31

Applicant: NOVARTIS AG

Inventor： Steven T. Charles ,  Michael Papac

IPC: A61B3/00 ,  A61B3/14 ,  A61B3/13 ,  A61F9/007

CPC classification number: A61B3/0025 ,  A61B3/0008 ,  A61B3/0041 ,  A61B3/12 ,  A61B3/13 ,  A61B3/14 ,  A61B5/0071 ,  A61B5/4836 ,  A61B2576/02 ,  A61F9/0008 ,  A61F9/00736 ,  A61F9/008

Abstract: A method of imaging in an ophthalmic surgical procedure can include determining an excitation wavelength of light associated with a vital stain; transmitting light having the excitation wavelength; determining an emission wavelength of light associated with the vital stain; filtering light using a first optical element to allow transmission of light having the emission wavelength and to block light having the excitation wavelength. An ophthalmic surgical imaging system can include a light source, one or more optical elements, an image sensor, a computing device, and/or a display device to visualize target biological tissue stained with a fluorescent vital stain. A method of imaging in an ophthalmic surgical procedure can include determining a wavelength of light that increases the visual contrast of a vital stain; transmitting light having the determined wavelength; and receiving a reflection of the transmitted light such that target biological tissue stained by the vital stain is accentuated.

Abstract translation: 在眼科外科手术中成像的方法可以包括确定与生物污渍相关联的光的激发波长; 透射具有激发波长的光; 确定与生物污渍相关的光的发射波长; 使用第一光学元件过滤光以允许具有发射波长的光的透射并阻挡具有激发波长的光。 眼科手术成像系统可以包括光源，一个或多个光学元件，图像传感器，计算装置和/或显示装置，以使用荧光生物污渍染色的靶生物组织可视化。 在眼科外科手术中成像的方法可以包括确定增加生物污渍的视觉对比度的光的波长; 透射具有确定波长的光; 并且接收透射光的反射，使得被生物染色染色的靶生物体被加强。