-
公开(公告)号：US10398312B2
公开(公告)日：2019-09-03
申请号：US15882888
申请日：2018-01-29
Applicant: Novartis AG
Inventor： Cesario Dos Santos , Gerald David Bacher , Ronald Smith , Alireza Mirsepassi , Michael Papac
Abstract: Frequency-based mode mixing may be used to homogenize different modes in an optical fiber used for surgical illumination. A laser modulator may introduce frequency modulation to laser light to generate a homogeneous illumination field due to increased mode mixing in the optical fiber.
-
公开(公告)号：US20180214021A1
公开(公告)日：2018-08-02
申请号：US15882888
申请日：2018-01-29
Applicant: Novartis AG
Inventor： Cesario Dos Santos , Gerald David Bacher , Ronald Smith , Alireza Mirsepassi , Michael Papac
CPC classification number: A61B3/13 , A61B3/0008 , A61B90/30 , A61B2090/306 , G02B21/0012 , G02B21/06 , H01S3/005 , H01S3/0057 , H01S3/0085
Abstract: Frequency-based mode mixing may be used to homogenize different modes in an optical fiber used for surgical illumination. A laser modulator may introduce frequency modulation to laser light to generate a homogeneous illumination field due to increased mode mixing in the optical fiber.
-
公开(公告)号：US20150164687A1
公开(公告)日：2015-06-18
申请号：US14132859
申请日：2013-12-18
Applicant: Novartis AG
Inventor： Pooria S. Kashani , Michael Papac
IPC: A61F9/00
CPC classification number: A61F9/0017 , A61B17/00491 , A61F9/0008 , A61M5/178 , A61M5/32
Abstract: A retinal treatment system for delivering therapeutic agents to a target location with a retina is disclosed herein. The retinal treatment system includes a console having a control system and a handheld device coupled to the control system. The handheld device includes an inner tube disposed within an outer tube and being axially moveable within the outer tube. The inner tube has a perforating tip that is configured to perforate an inner limiting membrane of the retina. The handheld device further includes a chamber coupled to a proximal end of the inner tube that is configured to receive a fluid containing therapeutic agents injectable from the perforating tip. The control system of the retinal treatment system permits a user to maintain a position of the handheld device relative to the retina and activate an injection of a portion of the fluid through the inner tube into the retina.
Abstract translation: 本文公开了用于将治疗剂递送至具有视网膜的目标位置的视网膜处理系统。 视网膜处理系统包括具有控制系统和耦合到控制系统的手持设备的控制台。 手持式装置包括设置在外管内并可在外管内轴向移动的内管。 内管具有穿孔端头，其被配置成穿透视网膜的内部限制膜。 手持装置还包括联接到内管的近端的腔室，其被构造成接收含有可从穿孔尖端注射的治疗剂的流体。 视网膜处理系统的控制系统允许使用者维持手持式装置相对于视网膜的位置，并激活通过内管将一部分流体注入视网膜。
-
公开(公告)号：US10779905B2
公开(公告)日：2020-09-22
申请号：US15882790
申请日：2018-01-29
Applicant: Novartis AG
Inventor： Cesario Dos Santos , Gerald David Bacher , Ronald Smith , Alireza Mirsepassi , Michael Papac
Abstract: Focusing optics for mode mixing may be used to homogenize different modes in an optical fiber used for surgical illumination. A vibration stage may impart mechanical motion to a condenser lens to generate a homogeneous illumination field from a coherent light source.
-
公开(公告)号：US10687912B2
公开(公告)日：2020-06-23
申请号：US15882758
申请日：2018-01-29
Applicant: Novartis AG
Inventor： Cesario Dos Santos , Gerald David Bacher , Ronald Smith , Alireza Mirsepassi , Michael Papac
Abstract: Fiber-based mode mixing techniques may be used to homogenize different modes in an optical fiber used for surgical illumination. A vibrating fiber mechanism may impart mechanical motion to a portion of the optical fiber to generate a homogeneous illumination field from a coherent light source.
-
Patent Agency Ranking
6.发明授权公开(公告)号：US10292783B2
公开(公告)日：2019-05-21
申请号：US14723654
申请日：2015-05-28
Applicant: NOVARTIS AG
Inventor： Gerald D. Bacher , Steven T. Charles , Eyad Ammari , Paul Hallen , Michael Papac , Ronald T. Smith
Abstract: An ophthalmic illumination system includes a light source generating a source light beam and a beam splitter splitting the source light beam into first and second light beams. A first attenuator is located in a path of the first light beam and a second attenuator is located in the path of the second light beam, the first and second attenuators operable to change the intensities of the first and second light beams, respectively. A first optical fiber port is configured for connection to a first optical fiber for delivering the first light beam to a patient's eye and a second optical fiber port is configured for connection to a second optical fiber for delivering the second light beam to the patient's eye. A control unit is communicatively coupled to the first and second attenuators and is operable to adjust the attenuators to control the intensities of the light beams delivered to the patient's eye.
-
公开(公告)号：US09844314B2
公开(公告)日：2017-12-19
申请号：US14444437
申请日：2014-07-28
Applicant: NOVARTIS AG
Inventor： Steven T. Charles , Michael Papac
CPC classification number: A61B3/0025 , A61B3/13 , A61B3/132 , A61B90/20 , G02B21/22 , G02B21/241 , G02B27/0075
Abstract: An ophthalmic surgical microscope can include a movable optical element positioned in an optical pathway of light reflected from a surgical field. The movable optical element can be configured to oscillate in a direction along the optical pathway. The microscope can include an actuator coupled to the movable optical element and configured to move in response to a control signal. The microscope can include a computing device in communication with the actuator and configured to generate the control signal to move the movable optical element. In some embodiments, the computing device is configured to generate the control signal to move the movable optical element with an oscillation frequency greater than the critical flicker fusion rate.
-
公开(公告)号：US09639917B2
公开(公告)日：2017-05-02
申请号：US14877638
申请日：2015-10-07
Applicant: NOVARTIS AG
Inventor： Lingfeng Yu , Hugang Ren , Michael Papac
CPC classification number: G06T5/001 , A61B3/102 , A61B3/13 , A61B90/20 , G02B21/0012 , G06T5/005 , G06T7/70 , G06T2207/10101 , G06T2207/30164
Abstract: According to some examples, a method for Optical Coherence Tomography (OCT) image modification includes receiving an OCT image of a region of interest of patient tissue from an OCT imaging system configured to direct an OCT beam at the region of interest and determining that an OCT transparent instrument is within the OCT image. The method further includes detecting an artifact in the OCT image, the artifact resulting from the OCT transparent instrument being within a path of the OCT beam. In response to detecting the artifact, the method further includes creating an image modification plan to remove the artifact from the OCT image. The method further includes executing the image modification plan to remove the artifact from the OCT image.
-
公开(公告)号：US09554702B2
公开(公告)日：2017-01-31
申请号：US14576306
申请日：2014-12-19
Applicant: NOVARTIS AG
Inventor： Michael Papac , Lingfeng Yu , Tammo Heeren
CPC classification number: A61B3/102 , G02B21/0012 , G02B27/141
Abstract: A surgical imaging system can comprise a light source, configured to generate an imaging light beam; a beam guidance system, configured to guide the imaging light beam from the light source; a beam scanner, configured to receive the imaging light from the beam guidance system, and to generate a scanned imaging light beam; a beam coupler, configured to redirect the scanned imaging light beam; and a wide field of view (WFOV) lens, configured to guide the redirected scanned imaging light beam into a target region of a procedure eye.
Abstract translation: 手术成像系统可以包括被配置为产生成像光束的光源; 光束引导系统，被配置为引导来自光源的成像光束; 光束扫描器，其被配置为从所述光束引导系统接收成像光，并且生成扫描的成像光束; 光束耦合器，被配置为重定向扫描的成像光束; 和宽视野（WFOV）透镜，被配置为将重定向的扫描成像光束引导到过程眼睛的目标区域中。
-
10.发明申请公开(公告)号：US20160029892A1
公开(公告)日：2016-02-04
申请号：US14446586
申请日：2014-07-30
Applicant: NOVARTIS AG
Inventor： Steven T. Charles , Michael Papac
CPC classification number: A61B3/0025 , A61B3/0008 , A61B3/0041 , A61B3/12 , A61B3/13 , A61B3/14 , A61B5/0071 , A61B5/4836 , A61B2576/02 , A61F9/0008 , A61F9/00736 , A61F9/008
Abstract: A method of imaging in an ophthalmic surgical procedure can include determining an excitation wavelength of light associated with a vital stain; transmitting light having the excitation wavelength; determining an emission wavelength of light associated with the vital stain; filtering light using a first optical element to allow transmission of light having the emission wavelength and to block light having the excitation wavelength. An ophthalmic surgical imaging system can include a light source, one or more optical elements, an image sensor, a computing device, and/or a display device to visualize target biological tissue stained with a fluorescent vital stain. A method of imaging in an ophthalmic surgical procedure can include determining a wavelength of light that increases the visual contrast of a vital stain; transmitting light having the determined wavelength; and receiving a reflection of the transmitted light such that target biological tissue stained by the vital stain is accentuated.
-
-
-
-
-
-
-
-
-
Search Results
24
records
(took 0.013 seconds)
