摘要:
Disclosed is a synthesis method of a compound of formula 1,5-[[2(R)-[1(R)-[3,5-bis(trifluoromethyl)phenyl]ethoxyl]-3(S)-4-fluorophenyl-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazole-3-one (i.e. aprepitant), which comprises cyclizing a compound of formula 4 in a solvent, wherein R is C1-C5 alkyl. The intermediate for preparing aprepitant is also disclosed. The present method is especially suitable for industrial production of aprepitant.
摘要:
An intelligent system that supports real-time and offline feedback based on automated analysis of a trainee's performance using data streams captured in the training process is disclosed.
摘要:
A degradable, removable, pharmaceutical implant for the sustained release of one or more drugs in a subject, wherein the pharmaceutical implant is composed of a tube comprising an outer wall made of a degradable polymer completely surrounding a cavity, wherein the outer wall has a plurality of openings and wherein the cavity contains one or more sets of micro-particles, which micro-particles contain an active agent or a combination of two or more active agents, and wherein the size of the microparticles is selected such that the majority of the microparticles cannot pass through the openings.
摘要:
A method and system for implementing large capacity calls by using the H.323 protocol stack are provided in the present invention. The method comprises: a plurality of protocol stacks are deployed in a multi-point control unit; an IP address of a third protocol stack is pre-configured as a uniform IP address of the multi-point control unit, wherein the IP address acts as an incoming address when the multi-point control unit is called, and the third protocol stack is used to perform the H.225 signaling interaction with the opposite end when the multi-point control unit is a called party; when the multi-point control unit is a calling party, a first protocol stack, the number of processable calls of which does not exceed a limit number, is selected to perform the H.225 signaling interaction with the opposite end, and a second protocol stack, the number of processable calls of which does not exceed a limit number, is selected to perform the H.245 signaling interaction with the opposite end; when the multi-point control unit is a called party, a fourth protocol stack, the number of processable calls of which does not exceed a limit number, is selected to perform the H.245 signaling interaction with the opposite end. In the present invention, the H.245 messages from different ends are distributed to a plurality of protocol stacks for processing, which thereby improves the processing efficiency.
摘要:
A process for preparing a particle defoamer. The particle defoamer of 55%-75% of a carrier, 15%-35% of a silicone emulsion, 3%-10% of a texturing agent and 2%-10% of a solvent, based on the total weight of the particle defoamer; the process for preparing the particle defoamer is: (1)first adding a carrier A1 into a mixer, and then adding thereto a silicone emulsion B1, and stirring uniformly; (2)adding a carrier component A2 to the mixture obtained in (1), and stirring uniformly; (3)adding a silicone emulsion B2 to the mixture obtained in (2), and, after uniformly stirring, adding the solvent thereto and stirring uniformly; and (4)pelleting and drying by baking the mixture obtained in(3), so as to produce the product.
摘要:
Methods and arrangements (600) in a first network node (120-1) for managing handover of a user equipment (110) from the first network node (120-1), to a second network node (120-2). The method and arrangement (600) comprises transmitting (501) a handover message to the user equipment (110), which handover message is triggering the user equipment (110) to perform the handover, and to establishing (502) a limit related to the amount of retransmissions to be made. Further the method and arrangement (600) comprises interrupting (503) scheduling of resources to the user equipment (110) and inhibiting further retransmissions of the handover message, when either the established limit is reached, or an indication that the user equipment (110) has left the first cell (130-1) is received. Also, methods and arrangements (800) in a in a second network node (120-2) are disclosed.
摘要:
Systems and methods for detecting defects on a wafer are provided. One method includes combining first image data and second image data, generated using different output generated using different values for focus of an inspection system, corresponding to substantially the same locations on the wafer thereby creating additional image data for the wafer and detecting defects on the wafer using the additional image data.
摘要:
A drop test device for testing the strength of a product includes an operating platform and a hanging mechanism. The operating platform includes a bottom board, a pillar substantially perpendicularly connected to the bottom board and a support member rotatably secured on the pillar. The hanging mechanism is mounted to the pillar, and includes a clamp member for positioning the product. The product is sandwiched by the clamp member so an arris of the product abuts the support member. The support plate is rotated away from the product, so the product can be disengaged from the clamp member and dropped towards the bottom board.
摘要:
An electronic device configured for defect detection is described. The electronic device includes a processor and instructions stored in memory that is in electronic communication with the processor. The electronic device performs background suppression on the image data based on a transform of the image data to obtain a score map. The electronic device also applies thresholding to the score map to generate a detection mask. The thresholding comprises bi-thresholding. The electronic device additionally detects any defects based on the detection mask. The electronic device further indicates any defects.
摘要:
A degradable, removable, pharmaceutical implant for the sustained release of one or more drugs in a subject, wherein the pharmaceutical implant is composed of a tube comprising an outer wall made of a degradable polymer completely surrounding a cavity, wherein the outer wall has a plurality of openings and wherein the cavity contains one or more sets of micro-particles, which micro-particles contain an active agent or a combination of two or more active agents, and wherein the size of the microparticles is selected such that the majority of the microparticles cannot pass through the openings.