公开(公告)号：US20190025296A1

公开(公告)日：2019-01-24

申请号：US16040504

申请日：2018-07-19

Applicant: Purdue Research Foundation

Inventor： Jeffrey Frederick Rhoads ,  Eric A. Nauman ,  Mackenzie Tweardy ,  Michael Wadas ,  Allison Kelly Murray ,  George Tsu-Chih Chiu ,  Nikhil Bajaj

IPC: G01N33/547 ,  C07K16/18

Abstract: A method of detecting a substance, wherein the method includes functionalizing a plurality of sensors, wherein the functionalizing the plurality of sensors comprises depositing a first material using a piezoelectrically actuated pipette system, wherein the first material includes a polymer, a receptor, and a solvent, wherein the solvent comprises dimethylformamide. The method further includes evaporating a solution of the first material wherein a residue after the evaporation comprises a functionalized chemical. Additionally, the method includes introducing a control material to a first set of sensors of the plurality of sensors using the piezoelectrically actuated pipette system. Further, the method includes introducing a test material to a second set of sensors of the plurality of sensors using the piezoelectrically actuated pipette system, wherein the test material comprises an analyte. Moreover the method includes determining a difference between a first resonant frequency shift in the first set of sensors of the plurality of sensors and a second resonant frequency shift in the second set of sensors of the plurality of sensors.

公开(公告)号：US20160290855A1

公开(公告)日：2016-10-06

申请号：US14973262

申请日：2015-12-17

Applicant: Purdue Research Foundation

Inventor： Jeffrey Frederick Rhoads ,  George Tsu-Chih Chiu ,  Nikhil Bajaj ,  Andrew Burke Sabater

IPC: G01H13/00

CPC classification number: G01H13/00 ,  G01L9/00 ,  G01P15/00 ,  G01P15/097

Abstract: A device and method for sensing including a sensor having a functional surface layer located to interact with a material to be sensed, the sensor having an output that produces a signal responsive one or more of inertia, stiffness, acceleration, pressure, radiation, chemical compounds, and biological compounds; and further including electronics including: an input coupled to the sensor to receive a first signal therefrom; and a non-linearity provider that applies one or more non-linear operations to the input signal to generate a non-linear second signal.

Abstract translation: 一种用于感测的装置和方法，包括具有功能表面层的传感器，所述功能表面层定位成与要感测的材料相互作用，所述传感器具有产生响应惯性，刚度，加速度，压力，辐射，化学化合物中的一种或多种的信号 ，和生物化合物; 并且还包括电子器件，包括：耦合到所述传感器以从其接收第一信号的输入; 以及向输入信号施加一个或多个非线性运算以产生非线性第二信号的非线性提供器。