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公开(公告)号：US20100034805A1
公开(公告)日：2010-02-11
申请号：US11930802
申请日：2007-10-31
IPC分类号： A61K39/395
CPC分类号： A61K38/57
摘要： Methods are described for preventing or reducing ischemia, e.g., cerebral ischemia, and/or reperfusion injury, e.g., reperfusion injury associated with cerebral ischemia, in a patient.
摘要翻译： 描述了用于预防或减少患者中局部缺血，例如脑缺血和/或再灌注损伤（例如与脑缺血相关的再灌注损伤）的方法。
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公开(公告)号：US20090082267A1
公开(公告)日：2009-03-26
申请号：US11930012
申请日：2007-10-30
CPC分类号： A61K38/57 , A61K9/0019 , A61K38/55 , C12N9/6445
摘要： Methods are described for preventing or reducing ischemia and/or systemic inflammatory response in a patient such as perioperative blood loss and/or systemic inflammatory response in a patient subjected to cardiothoracic surgery, e.g. coronary artery bypass grafting and other surgical procedures, especially when such procedures involve extra-corporeal circulation, such as cardiopulmonary bypass.
摘要翻译： 描述了用于预防或减少患者中缺血和/或全身炎症反应的方法，例如进行心胸外科手术的患者中的围手术期失血和/或全身炎症反应。 冠状动脉旁路移植术等外科手术，特别是当此类手术涉及体外循环，如体外循环时。
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公开(公告)号：US20080260752A1
公开(公告)日：2008-10-23
申请号：US11934181
申请日：2007-11-02
IPC分类号： A61K39/395 , A61P19/00
CPC分类号： A61K38/57 , A61K9/0019 , A61K38/55 , C12N9/6445
摘要： Methods are described for preventing or reducing ischemia and/or systemic inflammatory response in a patient such as perioperative blood loss and/or systemic inflammatory response in a patient subjected to cardiothoracic surgery, e.g. coronary artery bypass grafting and other surgical procedures, especially when such procedures involve extra-corporeal circulation, such as cardiopulmonary bypass.
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公开(公告)号：US20080131426A1
公开(公告)日：2008-06-05
申请号：US11930018
申请日：2007-10-30
IPC分类号： A61K39/395 , A61P43/00
CPC分类号： A61K38/57 , A61K9/0019 , A61K38/55 , C12N9/6445
摘要： Methods are described for preventing or reducing ischemia and/or systemic inflammatory response in a patient such as perioperative blood loss and/or systemic inflammatory response in a patient subjected to cardiothoracic surgery, e.g. coronary artery bypass grafting and other surgical procedures, especially when such procedures involve extra-corporeal circulation, such as cardiopulmonary bypass.
摘要翻译： 描述了用于预防或减少患者中缺血和/或全身炎症反应的方法，例如进行心胸外科手术的患者中的围手术期失血和/或全身炎症反应。 冠状动脉旁路移植术等外科手术，特别是当此类手术涉及体外循环，如体外循环时。
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公开(公告)号：US07276480B1
公开(公告)日：2007-10-02
申请号：US11323261
申请日：2005-12-30
CPC分类号： C07K14/8114 , C07K14/8121
摘要： Methods are described for preventing or reducing ischemia and/or systemic inflammatory response in a patient such as perioperative blood loss and/or systemic inflammatory response in a patient subjected to cardiothoracic surgery, e.g. coronary artery bypass grafting and other surgical procedures, especially when such procedures involve extra-corporeal circulation, such as cardiopulmonary bypass.
摘要翻译： 描述了用于预防或减少患者中缺血和/或全身炎症反应的方法，例如进行心胸外科手术的患者中的围手术期失血和/或全身炎症反应。 冠状动脉旁路移植术等外科手术，特别是当此类手术涉及体外循环，如体外循环时。
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公开(公告)号：US20070004910A1
公开(公告)日：2007-01-04
申请号：US11196627
申请日：2005-08-03
申请人： Daniel Sexton , Andrew Nixon , Anthony Williams , Robert Ladner , Qi-Long Wu
发明人： Daniel Sexton , Andrew Nixon , Anthony Williams , Robert Ladner , Qi-Long Wu
IPC分类号： C07K16/40
CPC分类号： C07K16/40 , A61K2039/505 , C07K2317/21 , C07K2317/55 , C07K2317/565 , C07K2317/76 , C07K2317/92 , G01N33/564 , G01N2800/122
摘要： The invention features hK1 binding polypeptides as well as compositions comprising such polypeptides and methods of making and using such polypeptides.
摘要翻译： 本发明的特征在于hK1结合多肽以及包含这种多肽的组合物以及制备和使用这些多肽的方法。
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公开(公告)号：US20110278112A1
公开(公告)日：2011-11-17
申请号：US13043554
申请日：2011-03-09
IPC分类号： F16D51/12
CPC分类号： F16D51/20 , F16D2121/14 , F16D2125/26 , F16D2125/30 , F16D2125/56
摘要： A brake includes a brake shoe moveable between an engaged position and a disengaged position and defining an axis of rotation of an associated brake drum. The brake includes an actuation shaft rotatable about a shaft axis and an actuation device for transferring rotational movement of the actuation shaft into movement of the brake shoe from the disengaged position to the engaged position. The axis of rotation is non-parallel to the shaft axis.
摘要翻译： 制动器包括可在接合位置和脱离位置之间移动并且限定相关联的制动鼓的旋转轴线的制动蹄。 制动器包括可围绕轴线旋转的致动轴和用于将致动轴的旋转运动转移到制动瓦从分离位置移动到接合位置的致动装置。 旋转轴线不平行于轴的轴线。
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公开(公告)号：US07329737B2
公开(公告)日：2008-02-12
申请号：US11196627
申请日：2005-08-03
IPC分类号： C07K16/00 , C07K16/24 , A61K39/395
CPC分类号： C07K16/40 , A61K2039/505 , C07K2317/21 , C07K2317/55 , C07K2317/565 , C07K2317/76 , C07K2317/92 , G01N33/564 , G01N2800/122
摘要： The invention features hK1 binding polypeptides as well as compositions comprising such polypeptides and methods of making and using such polypeptides.
摘要翻译： 本发明的特征在于hK1结合多肽以及包含这种多肽的组合物以及制备和使用这些多肽的方法。
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公开(公告)号：US20060151636A1
公开(公告)日：2006-07-13
申请号：US10520259
申请日：2003-06-20
申请人： Anthony Harcombe , Anthony Williams , Andy Male
发明人： Anthony Harcombe , Anthony Williams , Andy Male
IPC分类号： F02M63/00
CPC分类号： F02M47/027 , F02M45/08 , F02M63/0015 , F02M63/0045 , F02M63/0056 , F02M63/0073 , F02M63/0078
摘要： A control valve arrangement for use in controlling fuel pressure within a control chamber (30) includes a control valve member (32) which is movable between a first position in which the control chamber (30) communicates with a source of high pressure fuel, and a second position in which the control chamber (30) communicates with a low pressure fuel drain and communication between the control chamber (30) and the source of high pressure fuel is broken. The control valve arrangement also includes restricted flow means (55, 70, 86) for restricting the rate of flow of fuel from the control chamber (30) to the low pressure fuel drain when the control valve member (32) is moved from the first position to the second position. It is desirable for the restricted flow means to be configured and arranged such the rate of flow of fuel from the source of high pressure fuel to the low pressure drain for the period of time for which the control valve member (32) is moving between the second position and the first position is also restricted.
摘要翻译： 一种用于控制控制室（30）内的燃料压力的控制阀装置，包括控制阀构件（32），该控制阀构件可在控制室（30）与高压燃料源连通的第一位置和 控制室（30）与低压燃料排出口连通并且控制室（30）与高压燃料源之间的连通的第二位置被破坏。 控制阀装置还包括限制流量装置（55,70,86），用于当控制阀构件（32）从第一阀门（32）移动时，限制燃料从控制室（30）到低压燃油排放的流量 位置到第二个位置。 期望的是，限制流动装置被构造和布置成使得燃料从高压燃料源流到低压排放管的流量在控制阀构件（32）在 第二个位置和第一个位置也受到限制。
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公开(公告)号：US6158491A
公开(公告)日：2000-12-12
申请号：US860074
申请日：1997-08-28
CPC分类号： H05K3/282 , C23F11/149 , Y10T428/24917
摘要： A process for the corrosion protection of copper or copper alloy which process comprises contacting the surface with an aqueous solution of at least one compound of general formula (I), wherein X is N, Y is CR and Z is N, or X is N, Y is N and Z is N or CR or X is CR, Y is N and Z is N, where R is a hydrogen atom or R.sup.1, and R.sup.1 is an alkyl, aryl, aralkyl, halogen, trihalomethyl, amino, heterocyclic, NHR.sup.2, NR.sup.3 R.sup.4, CN, CO.sub.2 H, CO.sub.2 R.sup.5, OH or OR.sup.6 group, where each of R.sup.2 to R.sup.6 independently represents an alkyl, aryl, or aralkyl group. ##STR1##
摘要翻译： PCT No.PCT / GB95 / 02912 Sec。 371日期1997年8月28日 102（e）日期1997年8月28日PCT提交1995年12月13日PCT公布。 出版物WO96 / 20295 日期1996年7月4日铜或铜合金的腐蚀保护方法，该方法包括使表面与至少一种通式（I）的化合物的水溶液接触，其中X为N，Y为CR，Z为N ，或X为N，Y为N，Z为N或CR或X为CR，Y为N，Z为N，其中R为氢原子或R1，R1为烷基，芳基，芳烷基，卤素，三卤甲基 ，氨基，杂环，NHR 2，NR 3 R 4，CN，CO 2 H，CO 2 R 5，OH或OR 6基团，其中R 2至R 6各自独立地表示烷基，芳基或芳烷基。
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