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23 条记录 (耗时 0.02 秒)

    Simultaneous acquisition of differing image types
    21.
    发明授权
    Simultaneous acquisition of differing image types 有权
    同时采集不同的图像类型

    公开(公告)号：US08285015B2

    公开(公告)日：2012-10-09

    申请号：US12167104

    申请日：2008-07-02

    申请人： Stavros G. Demos

    发明人： Stavros G. Demos

    IPC分类号： G06K9/00 ,  A61B6/00

    CPC分类号： A61B1/043 ,  A61B1/00009 ,  A61B1/063 ,  A61B1/0638 ,  A61B1/307 ,  A61B1/313 ,  A61B5/0075 ,  A61B5/0086

    摘要： A system in one embodiment includes an image forming device for forming an image from an area of interest containing different image components; an illumination device for illuminating the area of interest with light containing multiple components; at least one light source coupled to the illumination device, the at least one light source providing light to the illumination device containing different components, each component having distinct spectral characteristics and relative intensity; an image analyzer coupled to the image forming device, the image analyzer decomposing the image formed by the image forming device into multiple component parts based on type of imaging; and multiple image capture devices, each image capture device receiving one of the component parts of the image. A method in one embodiment includes receiving an image from an image forming device; decomposing the image formed by the image forming device into multiple component parts based on type of imaging; receiving the component parts of the image; and outputting image information based on the component parts of the image. Additional systems and methods are presented.

    摘要翻译： 一个实施例中的系统包括用于从包含不同图像分量的感兴趣区域形成图像的图像形成装置; 照明装置，用于用包含多个部件的光照射感兴趣的区域; 耦合到照明装置的至少一个光源，所述至少一个光源向包含不同部件的照明装置提供光，每个部件具有不同的光谱特性和相对强度; 图像分析器，耦合到所述图像形成装置，所述图像分析器基于成像的类型，将由所述图像形成装置形成的图像分解为多个分量; 和多个图像捕获设备，每个图像捕获设备接收图像的一个组成部分。 一个实施例中的方法包括从图像形成装置接收图像; 基于成像的类型，将由图像形成装置形成的图像分解成多个部件; 接收图像的组成部分; 并且基于图像的组成部分输出图像信息。 介绍了其他系统和方法。

    Hyperspectral microscope for in vivo imaging of microstructures and cells in tissues
    22.
    发明授权
    Hyperspectral microscope for in vivo imaging of microstructures and cells in tissues 有权
    高光谱显微镜用于组织中微观结构和细胞的体内成像

    公开(公告)号：US07945077B2

    公开(公告)日：2011-05-17

    申请号：US11292406

    申请日：2005-11-30

    申请人： Stavros G. Demos

    发明人： Stavros G. Demos

    IPC分类号： G06K9/00

    CPC分类号： A61B5/417 ,  A61B5/0071 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/0088 ,  A61B5/0091 ,  G01N21/6458 ,  G01N21/6486 ,  G01N2021/4792 ,  G02B21/082 ,  G02B21/16

    摘要： An optical hyperspectral/multimodal imaging method and apparatus is utilized to provide high signal sensitivity for implementation of various optical imaging approaches. Such a system utilizes long working distance microscope objectives so as to enable off-axis illumination of predetermined tissue thereby allowing for excitation at any optical wavelength, simplifies design, reduces required optical elements, significantly reduces spectral noise from the optical elements and allows for fast image acquisition enabling high quality imaging in-vivo. Such a technology provides a means of detecting disease at the single cell level such as cancer, precancer, ischemic, traumatic or other type of injury, infection, or other diseases or conditions causing alterations in cells and tissue micro structures.

    摘要翻译： 利用光学高光谱/多模式成像方法和装置为实现各种光学成像方法提供高信号灵敏度。 这样的系统利用长工作距离的显微镜物镜，以便使预定组织的轴外照明，从而允许在任何光学波长的激发，简化设计，减少所需的光学元件，显着降低来自光学元件的光谱噪声，并允许快速图像 获取能够在体内实现高质量成像。 这种技术提供了检测单细胞水平的疾病的手段，例如癌症，癌前期，缺血性，创伤性或其它类型的损伤，感染或导致细胞和组织微结构改变的其它疾病或病症。