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60 条记录 (耗时 0.041 秒)

    Therapy control based on the rate of change of intracardiac impedance
    21.
    发明申请
    Therapy control based on the rate of change of intracardiac impedance 有权
    基于心内阻抗变化率的治疗控制

    公开(公告)号：US20070005114A1

    公开(公告)日：2007-01-04

    申请号：US11169339

    申请日：2005-06-29

    申请人： Rodney Salo ,  Joseph Pastore ,  Jeffrey Stahmann ,  Jesse Hartley

    发明人： Rodney Salo ,  Joseph Pastore ,  Jeffrey Stahmann ,  Jesse Hartley

    IPC分类号： A61N1/00

    CPC分类号： A61N1/36521 ,  A61N1/30

    摘要： A system comprising a medical device that includes an impedance measurement circuit adapted to be coupled to implantable electrodes to obtain an intracardiac impedance signal between electrodes, a therapy circuit operable to deliver a therapy to a subject, and a controller circuit coupled to the impedance measurement circuit and the therapy circuit. The controller circuit determines a time rate of change of the intracardiac impedance signal and adjusts at least one parameter related to therapy in a manner that alters the rate of change.

    摘要翻译： 一种包括医疗装置的系统，该医疗装置包括阻抗测量电路，该阻抗测量电路适于耦合到可植入电极以获得电极之间的心内阻抗信号，可操作以将治疗递送给受试者的治疗电路，以及耦合到所述阻抗测量电路 和治疗电路。 控制器电路确定心内阻抗信号的时间变化率，并且以改变变化率的方式调节与治疗相关的至少一个参数。

    Cardiac stimulation at high ventricular wall stress areas
    23.
    发明授权
    Cardiac stimulation at high ventricular wall stress areas 有权
    心室刺激在高心室壁应激区域

    公开(公告)号：US07725185B2

    公开(公告)日：2010-05-25

    申请号：US12070080

    申请日：2008-02-15

    申请人： Lili Liu ,  Rodney Salo

    发明人： Lili Liu ,  Rodney Salo

    IPC分类号： A61N1/365 ,  A61N1/05

    CPC分类号： A61N1/368 ,  A61N1/3627 ,  A61N1/3684

    摘要： An apparatus and method for reversing ventricular remodeling with electro-stimulatory therapy. A ventricle is paced by delivering one or more stimulatory pulses in a manner such that a stressed region of the myocardium is pre-excited relative to other regions in order to subject the stressed region to a lessened preload and afterload during systole. The unloading of the stressed myocardium over time effects reversal of undesirable ventricular remodeling.

    摘要翻译： 用电刺激治疗逆转心室重构的装置和方法。 通过递送一个或多个刺激脉冲以使得相对于其它区域预激励心肌的应激区域以使受压区域在收缩期间减轻预负荷和后负荷来起搏心室。 随着时间的推移，应力心肌的卸载会影响不良心室重构的逆转。

    Devices and methods to stimulate therapeutic angiogenesis for ischemia and heart failure
    25.
    发明申请
    Devices and methods to stimulate therapeutic angiogenesis for ischemia and heart failure 失效
    用于刺激局部缺血和心力衰竭的治疗性血管发生的装置和方法

    公开(公告)号：US20060030810A1

    公开(公告)日：2006-02-09

    申请号：US11244016

    申请日：2005-10-05

    申请人： Evgenia Mandrusov ,  Paul Consigny ,  Rodney Salo

    发明人： Evgenia Mandrusov ,  Paul Consigny ,  Rodney Salo

    IPC分类号： A61N1/30

    CPC分类号： A61N1/0568 ,  A61N1/056 ,  A61N1/306 ,  A61N1/326 ,  A61N2001/0585

    摘要： A device that includes an electrical output channel adapted to deliver a sub-threshold voltage, a lead that includes a proximal end adapted to be electrically connected to the electrical output channel and a distal end adapted to be placed in the blood conduit where the distal end of the lead is adapted to deliver a treatment agent that stimulates therapeutic angiogenesis, and at least one electrode on the distal end of the first lead.

    摘要翻译： 一种包括适于递送亚阈值电压的电输出通道的装置，包括适于电连接到电输出通道的近端的引线和适于放置在血管中的远端，其中远端 的铅适于递送刺激治疗性血管生成的治疗剂，以及至少一个电极在第一引线的远端。

    Using implanted sensors for feedback control of implanted medical devices
    27.
    发明授权
    Using implanted sensors for feedback control of implanted medical devices 有权
    使用植入式传感器对植入式医疗设备进行反馈控制

    公开(公告)号：US07742815B2

    公开(公告)日：2010-06-22

    申请号：US11223398

    申请日：2005-09-09

    申请人： Rodney Salo ,  Abhijeet Chavan

    发明人： Rodney Salo ,  Abhijeet Chavan

    IPC分类号： A61N1/36

    CPC分类号： A61N1/36564 ,  A61N1/3621 ,  A61N1/3925

    摘要： A system and method for administering a therapeutic treatment to the heart, includes a pressure sensor positioned in the pulmonary artery, an implantable medical device located remotely from the sensor, and communication means for communicating pressure data from the pressure sensor to the implantable medical device. The system includes a control module operatively coupled to the implantable medical device. The control module is adapted for comparing the pulmonary arterial pressure data to a pre-programmed value, adjusting an operating parameter of the implantable medical device based on the relationship of the pulmonary arterial pressure to the pre-programmed value, and repeating this process until the relationship between the pulmonary arterial pressure data and the pre-programmed value is such that no adjustment is necessary.

    摘要翻译： 用于向心脏施用治疗性治疗的系统和方法包括定位在肺动脉中的压力传感器，远离传感器定位的可植入医疗装置以及用于将压力数据从压力传感器传送到可植入医疗装置的连通装置。 该系统包括可操作地耦合到可植入医疗装置的控制模块。 控制模块适于将肺动脉压数据与预编程值进行比较，基于肺动脉压与预编程值的关系来调整可植入医疗装置的操作参数，并重复该过程直到 肺动脉压数据与预编程值之间的关系使得不需要调整。

    Cardiac pacing using sensed coronary vein blood temperature and left ventricular flow rate
    28.
    发明申请
    Cardiac pacing using sensed coronary vein blood temperature and left ventricular flow rate 失效
    心脏起搏使用感觉到的冠状动脉血液温度和左心室流速

    公开(公告)号：US20070112388A1

    公开(公告)日：2007-05-17

    申请号：US11651311

    申请日：2007-01-09

    申请人： Rodney Salo

    发明人： Rodney Salo

    IPC分类号： A61N1/365

    CPC分类号： A61N1/056 ,  A61N1/3627 ,  A61N1/3655 ,  A61N1/36571 ,  A61N2001/0585

    摘要： Methods of cardiac pacing involve sensing left ventricular electrical rhythms, sensing left ventricular blood flow rate, and sensing a coronary vein blood temperature. The methods further involve modifying delivery of synchronized electrical signals to the patient's heart based at least in part on the sensed coronary vein blood temperature and sensed left ventricular flow rate.

    摘要翻译： 心脏起搏方法涉及感测左心室电节律，感测左心室血流速度，以及感测冠状静脉血液温度。 所述方法还包括至少部分地基于感测的冠状静脉血液温度和感测的左心室流率来修改同步电信号到患者心脏的传送。

    Epicardial patch including isolated extracellular matrix with pacing electrodes
    29.
    发明申请
    Epicardial patch including isolated extracellular matrix with pacing electrodes 失效
    心外膜包括分离的细胞外基质与起搏电极

    公开(公告)号：US20060136028A1

    公开(公告)日：2006-06-22

    申请号：US11017627

    申请日：2004-12-20

    申请人： Jeffrey Ross ,  John Kim ,  Rodney Salo ,  Ronald Heil ,  Randy Westlund

    发明人： Jeffrey Ross ,  John Kim ,  Rodney Salo ,  Ronald Heil ,  Randy Westlund

    IPC分类号： A61N1/05

    CPC分类号： A61N1/0587 ,  A61N1/0568 ,  A61N1/059

    摘要： An epicardial patch includes an extracellular matrix (ECM) and a plurality of electrodes. The isolated ECM is configured for epicardial attachment over a myocardial region including an injured area to control post-injury remodeling of the myocardial region. The plurality of electrodes is configured for delivering electrical stimulation to enhance the effect of the isolated ECM in remodeling control by altering workload and stress on the myocardial region.

    摘要翻译： 心外膜贴片包括细胞外基质（ECM）和多个电极。 分离的ECM被配置用于在包括受伤区域的心肌区域上的心外膜附着以控制心肌区域的损伤后重建。 多个电极被配置为通过改变心肌区域上的工作负荷和压力来传递电刺激以增强孤立的ECM在重塑控制中的作用。