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60 条记录 (耗时 0.044 秒)

    Methods of producing collection assemblies, laminates, and autosensor assemblies for use in transdermal sampling systems
    25.
    发明授权
    Methods of producing collection assemblies, laminates, and autosensor assemblies for use in transdermal sampling systems 有权
    生产用于透皮采样系统的收集组件，层压板和自动传感器组件的方法

    公开(公告)号：US06341232B1

    公开(公告)日：2002-01-22

    申请号：US09810917

    申请日：2001-03-16

    申请人： Thomas E. Conn ,  Russell Ford ,  Pravin L. Soni ,  Michael J. Tierney ,  Prema Vijayakumar

    发明人： Thomas E. Conn ,  Russell Ford ,  Pravin L. Soni ,  Michael J. Tierney ,  Prema Vijayakumar

    IPC分类号： A61N130

    CPC分类号： A61B5/1486

    摘要： The invention relates generally to methods of producing consumable components of a device used for measuring the concentration of target chemical analytes present in a biological system. More particularly, the invention relates methods of producing collection assemblies, laminate structures, and autosensor assemblies, which are used in connection with a transdermal sampling device. In one aspect, the invention includes methods of producing autosensor assemblies which include laminate structures, electrode assemblies, and support trays. One important application of the invention involves methods of producing an autosensor assembly for use in a blood glucose monitoring device.

    摘要翻译： 本发明一般涉及生产用于测量存在于生物系统中的目标化学分析物的浓度的装置的消耗性组分的方法。 更具体地说，本发明涉及生产与经皮采样装置结合使用的收集组件，层压结构和自动传感器组件的方法。 一方面，本发明包括制造包括层压结构，电极组件和支撑托盘的自动传感器组件的方法。 本发明的一个重要应用涉及生产用于血糖监测装置的自动传感器组件的方法。

    Sensing Fluid Concentration for Continuous Glucose Monitoring
    26.
    发明申请
    Sensing Fluid Concentration for Continuous Glucose Monitoring 审中-公开
    感测液体浓度用于连续葡萄糖监测

    公开(公告)号：US20120172692A1

    公开(公告)日：2012-07-05

    申请号：US12985224

    申请日：2011-01-05

    申请人： Janet Tamada ,  Michael J. Tierney ,  Ramakrishna Madabhushi ,  Arvind N. Jina

    发明人： Janet Tamada ,  Michael J. Tierney ,  Ramakrishna Madabhushi ,  Arvind N. Jina

    IPC分类号： A61B5/1486

    CPC分类号： A61B5/14514 ,  A61B5/14532 ,  A61B5/14865 ,  A61B5/685

    摘要： An analyte monitor having a plurality of fluid paths, each fluid path having a distal opening adapted to be disposed on one side of a stratum corneum layer of a user's skin, a proximal opening adapted to be disposed on another side of the stratum corneum layer and an interior space extending between the distal and proximal openings; a sensing zone in fluid communication with the proximal openings of the fluid paths; sensing fluid extending from the sensing zone into substantially the entire interior space of the fluid paths; and an analyte sensor adapted to detect a concentration of analyte in the sensing fluid within the sensing zone, wherein at least one of the sensing fluid and the analyte sensor comprises a catalyst for mutarotation of glucose. The invention also includes a method of using the monitor.

    摘要翻译： 一种具有多个流体路径的分析物监测器，每个流体路径具有适于设置在使用者皮肤的角质层的一侧上的远端开口，适于设置在角质层的另一侧上的近侧开口，以及 在远端和近端开口之间延伸的内部空间; 与流体路径的近端开口流体连通的感测区域; 从所述感测区域延伸到所述流体路径的基本上整个内部空间中的感测流体; 以及分析物传感器，其适于检测所述感测区域内的所述感测流体中的分析物的浓度，其中所述感测流体和所述分析物传感器中的至少一个包括用于葡萄糖变异的催化剂。 本发明还包括使用监视器的方法。

    DEVICES, SYSTEMS, METHODS AND TOOLS FOR CONTINUOUS ANALYTE MONITORING
    28.
    发明申请
    DEVICES, SYSTEMS, METHODS AND TOOLS FOR CONTINUOUS ANALYTE MONITORING 审中-公开
    用于连续分析监测的设备，系统，方法和工具

    公开(公告)号：US20100049021A1

    公开(公告)日：2010-02-25

    申请号：US12545008

    申请日：2009-08-20

    申请人： Arvind N. Jina ,  Ashok Parmar ,  Beelee Chua ,  Janet Tamada ,  Jonathan Lee ,  Michael J. Tierney ,  Navneet Kaur ,  Paul Magginetti ,  Shashi P. Desai

    发明人： Arvind N. Jina ,  Ashok Parmar ,  Beelee Chua ,  Janet Tamada ,  Jonathan Lee ,  Michael J. Tierney ,  Navneet Kaur ,  Paul Magginetti ,  Shashi P. Desai

    IPC分类号： A61B5/1468

    CPC分类号： A61B5/14532 ,  A61B5/14514 ,  A61B5/14865 ,  A61B2560/0223

    摘要： One aspect of the invention provides an analyte monitor including a sensing volume, an analyte extraction area in contact with the sensing volume adapted to extract an analyte into the sensing volume, and an analyte sensor adapted to detect a concentration of analyte in the sensing volume. The sensing volume is defined by a first face, a second face opposite to the first face, and a thickness equal to the distance between the two faces. The surface area of the first face is about equal to the surface area of the second face and the extraction area is about equal to the surface area of the first and second face of the sensing volume. The analyte sensor includes a working electrode in contact with the sensing volume, the working electrode having a surface area at least as large as the analyte extraction area, and a second electrode in fluid communication with the sensing volume.

    摘要翻译： 本发明的一个方面提供一种分析物监测器，其包括感测体积，与适于将分析物提取到感测体积中的感测体接触的分析物提取区域，以及适于检测感测体积中的分析物浓度的分析物传感器。 感测体积由第一面，与第一面相反的第二面和厚度等于两个面之间的距离限定。 第一面的表面积约等于第二面的表面积，并且提取面积大约等于感测体积的第一和第二面的表面积。 分析物传感器包括与感测体积接触的工作电极，工作电极具有至少与分析物提取区域一样大的表面积，以及与感测体积流体连通的第二电极。

    Electrochemical sensor ink compositions, electrodes, and uses thereof
    30.
    发明授权
    Electrochemical sensor ink compositions, electrodes, and uses thereof 有权

    公开(公告)号：US07189341B2

    公开(公告)日：2007-03-13

    申请号：US10692761

    申请日：2003-10-24

    申请人： Huawen Li ,  Michael J. Tierney

    发明人： Huawen Li ,  Michael J. Tierney

    IPC分类号： H01B1/22 ,  C25B11/04 ,  G01N27/327

    CPC分类号： C09D11/52 ,  C09D11/101 ,  C09D11/30 ,  G01N27/3271

    摘要： The invention is directed to conductive polymer compositions, catalytic ink compositions (e.g., for use in screen-printing), electrodes produced by deposition of an ink composition, as well as methods of making, and methods of using such compositions and electrodes. An exemplary ink material comprises a metal catalyst (e.g., platinum black and/or platinum-on-carbon), graphite as a conducting material, a polymer binding material, and an organic solvent. In one aspect, the polymer binding material comprises a polymer binder blend comprising first and second polymers, wherein the first polymer has a glass transition temperature higher than the second polymer. In a second aspect, the polymer binding material comprises a hydrophilic acrylic polymer, copolymer, or terpolymer. The conductive polymer compositions of the present invention may be used, for example, to make electrochemical sensors. Such sensors may be used, for example, in a variety of devices to monitor analyte amount or concentrations in subjects.