Dihydropyridine derivative
    21.
    发明授权
    Dihydropyridine derivative 有权
    二氢吡啶衍生物

    公开(公告)号:US06350766B1

    公开(公告)日:2002-02-26

    申请号:US09403592

    申请日:1999-10-25

    IPC分类号: A61K31455

    摘要: Dihydropyridine derivatives of the following formula, analogs thereof and pharmaceutically acceptable salts thereof have an activity of selectively inhibiting the action of N-type calcium channel. They are used as remedies for various diseases relating to the N-type calcium channel such as encephalopathies caused by the ischemia in the acute phase after the onset of cerebral infarction, cerebral hemorrhage or the like, Alzheimer's disease, etc.

    摘要翻译: 下式的二氢吡啶衍生物,其类似物和其药学上可接受的盐具有选择性抑制N型钙通道作用的活性。 它们被用作与N型钙通道有关的各种疾病的补救措施,例如脑梗死发作后急性期缺血引起的脑病,脑出血等,阿尔茨海默病等。

    INDEXABLE BALL END MILL
    23.
    发明申请
    INDEXABLE BALL END MILL 有权
    可选球头

    公开(公告)号:US20130336731A1

    公开(公告)日:2013-12-19

    申请号:US14002599

    申请日:2012-03-05

    IPC分类号: B23C5/10

    摘要: An indexable ball end mill comprising first to third inserts having arcuate cutting edges detachably attached with first to third screws to first to third seats in a semispherical tip end portion of a tool body; a first threaded hole for the first screw slantingly penetrating a slit-shaped first seat; the first insert having an inclined hole to avoid interference between the first screw and the second and third screws; a hole of the first insert and the first screw having at least partially finished surfaces, so that when the first screw penetrates the first insert attached to the first seat, the first insert is precisely positioned by tight engagement of both finished surfaces.

    摘要翻译: 一种可转位球头立铣刀,包括具有弓形切割刃的第一至第三刀片,刀片主体的半球形末端部分可拆卸地与第一至第三螺钉连接至第一至第三座椅; 第一螺钉的第一螺纹孔倾斜地穿过狭缝状的第一座; 所述第一插入件具有倾斜孔,以避免所述第一螺钉和所述第二和第三螺钉之间的干涉; 第一插入件的孔和第一螺钉具有至少部分最终表面,使得当第一螺钉穿过附接到第一座椅的第一插入件时,通过两个成品表面的紧密接合来精确地定位第一插入件。