公开(公告)号：US20070211856A1

公开(公告)日：2007-09-13

申请号：US11705494

申请日：2007-02-13

申请人： Susumu Urano ,  Shuji Kaneko ,  Noriyuki Kawada

发明人： Susumu Urano ,  Shuji Kaneko ,  Noriyuki Kawada

IPC分类号： A61N5/10

CPC分类号： A61N5/1049 ,  A61N5/1069 ,  A61N2005/1059 ,  A61N2005/1062

摘要： A radiotherapy device control apparatus controlling a radiotherapy device, includes a reference image creation section; a transmitted image creation section and an affected area position control section. The radiotherapy device includes a therapeutic radiation irradiation device radiating therapeutic radiation, an imager generating an image of a subject by using radiation transmitted through the subject, and a drive device moving a couch, where the subject is arranged, with respect to the therapeutic radiation irradiation device. The reference image creation section collects a reference image taken by the imager. The transmitted image creation section takes a transmitted image of the subject by the imager. The affected area position control section judge whether a relative position of the couch with respect to the therapeutic radiation irradiation device is appropriate based on a position where a characteristic point of the subject is displayed in the transmitted image and a position where the characteristic point is displayed in the reference image. The affected area position control section changes the relative position of the couch by using the drive device based on the first position and the second position.

摘要翻译： 一种控制放射线治疗装置的放射线治疗装置控制装置，包括：参照图像生成部; 发送图像生成部和受影响区域位置控制部。 放射治疗装置包括放射治疗辐射的治疗放射线照射装置，通过使用通过被检体传播的辐射而产生被检体的图像的成像器，以及移动被检体相对于治疗射线照射的沙发的驱动装置 设备。 参考图像创建部分收集由成像器拍摄的参考图像。 发送图像创建部件通过成像器拍摄被摄体的发送图像。 受影响区域位置控制部分基于在发送图像中显示被摄体的特征点的位置和显示特征点的位置来判断沙发相对于治疗放射线照射装置的相对位置是否适当 在参考图像中。 受影响区域位置控制部通过使用基于第一位置和第二位置的驱动装置改变沙发的相对位置。

公开(公告)号：US08471222B2

公开(公告)日：2013-06-25

申请号：US12808312

申请日：2009-11-18

申请人： Takanobu Handa ,  Shuji Kaneko ,  Noritaka Yanai

发明人： Takanobu Handa ,  Shuji Kaneko ,  Noritaka Yanai

IPC分类号： A61N5/10 ,  G21K5/10 ,  G06T7/20

CPC分类号： A61N5/1069 ,  A61N2005/1061 ,  G06K9/00 ,  G21K5/10

摘要： A radiotherapy apparatus control method according to the present invention includes: a step S6 of calculating rotational and first translational correction amounts based on a position and orientation of a first region represented by a radioscopic image of a subject; and a step S9 of calculating a second translational correction amount based on a position and orientation of the second region represented by the radioscopic image and the rotational correction amount; and a step S10 of driving a couch so that it rotates by the rotational correction amount and translates by the second translational correction amount. The first region is larger than the second region. According to such a method, the second region can be arranged in a predetermined position at higher accuracy compared with a case where the position of the couch is adjusted by using the position and orientation of only one of the first and second regions.

摘要翻译： 根据本发明的放射治疗装置控制方法包括：步骤S6，其基于由被检体的放射线图像表示的第一区域的位置和取向来计算旋转和第一平移校正量; 以及基于由放射线图像表示的第二区域和旋转校正量的位置和取向来计算第二平移校正量的步骤S9; 以及步骤S10，其驱动沙发使得其以旋转校正量旋转并平移第二平移校正量。 第一区域大于第二区域。 根据这种方法，与通过仅使用第一和第二区域中的一个的位置和取向来调节沙发的位置的情况相比，可以以更高的精度将第二区域布置在预定位置。

公开(公告)号：US20110268244A1

公开(公告)日：2011-11-03

申请号：US12679102

申请日：2009-09-14

申请人： Takanobu Handa ,  Shuji Kaneko

发明人： Takanobu Handa ,  Shuji Kaneko

IPC分类号： A61B6/03

CPC分类号： A61B6/022 ,  A61B6/032 ,  A61B6/4014 ,  A61B6/466 ,  A61B6/542 ,  A61N5/1049 ,  A61N2005/1061

摘要： A radiation tomography method of the present invention includes: calculating a radiating timing, with reference to imaging timing correction data relating a plurality of gantry angles to a plurality of imaging timing correction amounts, on the basis of an imaging timing at which a radiation source supported by a rotating traveling gantry is arranged at a predetermined imaging angle and an imaging timing correction amount, of the plurality of imaging timing correction amounts, related to a gantry angle at which the traveling gantry is arranged at the imaging timing; and calculating, on the basis of an X-ray image imaged with a radiation radiated from the radiation source at the radiating timing, three-dimensional data of the X-ray image of a subject. According to the radiation tomography method, the X-ray image imaged with the further accurately arranged radiation can be obtained even in a case where the traveling gantry deflects depending on the gantry angle at which the traveling gantry is arranged, and thus the three-dimensional data can be obtained more accurately.

摘要翻译： 本发明的放射线断层摄影方法包括：基于成像定时，基于成像定时，将成像定时校正数据与多个成像定时校正量相关联的成像定时校正数据基于成像定时来计算， 通过旋转移动台架被布置成与在成像定时处布置行进台架的台架角度相关的多个成像定时校正量的预定成像角度和成像定时校正量; 并且基于在辐射时刻从辐射源辐射的辐射成像的X射线图像，计算被检体的X射线图像的三维数据。 根据放射线断层摄影方法，即使在行走机架根据配置有行走机架的台架角度而偏转的情况下，也能够获得以更准确排列的放射线成像的X射线图像，因此可以获得三维 可以更准确地获得数据。

公开(公告)号：US08005190B2

公开(公告)日：2011-08-23

申请号：US12549824

申请日：2009-08-28

申请人： Osamu Shibuya ,  Shuji Kaneko ,  Kunio Takahashi

发明人： Osamu Shibuya ,  Shuji Kaneko ,  Kunio Takahashi

IPC分类号： A61N5/10

CPC分类号： A61N5/1049 ,  A61N2005/1054 ,  A61N2005/1061

摘要： A radiotherapy apparatus controller includes: a portal image taking unit; a gantry position collector; a marker position calculator; and a marker position table generator. The portal image taking unit takes a first transmission image, in which a marker member positioned at a predetermined position is shown, by using therapeutic radiation and an imager. The gantry position collector collects a first gantry position at which a gantry is positioned when the first transmission image is taken from a sensor measuring a position at which the gantry is positioned, the gantry supporting the imager and a therapeutic radiation radiating device which radiates the therapeutic radiation. The marker position calculator calculates a first marker position at which the marker member is shown in the first transmission image. The marker position table generator updates a marker position table, which correlates a plurality of gantry positions with a plurality of marker positions, so that the first gantry position corresponds to the first marker position.

摘要翻译： 放射治疗装置控制器包括：门静脉图像摄取单元; 台架收集器 标记位置计算器 和标记位置表生成器。 门静脉图像摄取单元采用第一透射图像，其中示出了位于预定位置处的标记构件，通过使用治疗辐射和成像器。 当从测量台架所在位置的传感器取得第一透射图像时，台架位置收集器收集第一台架位置，在该第一台架位置，当第一透射图像被取自测量台架所在位置的传感器，支撑成像器的台架和辐射治疗 辐射。 标记位置计算器计算在第一透射图像中显示标记构件的第一标记位置。 标记位置表发生器更新标记位置表，其将多个机架位置与多个标记位置相关联，使得第一机架位置对应于第一标记位置。

公开(公告)号：US07935939B2

公开(公告)日：2011-05-03

申请号：US12261936

申请日：2008-10-30

申请人： Tatsufumi Aoi ,  Shuji Kaneko ,  Osamu Shibuya

发明人： Tatsufumi Aoi ,  Shuji Kaneko ,  Osamu Shibuya

IPC分类号： A61B8/00

CPC分类号： A61N5/1049 ,  A61N5/1067 ,  A61N2005/1059 ,  A61N2005/1061

摘要： A radiotherapy apparatus controller includes: a movement collection section; a sensor control section configured to change a first time interval in which a second sensor measures a position of an irradiation area in the subject, based on the movement information; and an irradiation control section. The movement collection section collects movement information indicating a movement of a subject from a first sensor. The sensor control section changes a first time interval in which a second sensor measures a position of an irradiation area in the subject, based on the movement information. The irradiation control section controls a radiotherapy apparatus such that therapeutic radiation irradiated to the irradiation area is changed based on the position.

摘要翻译： 放射治疗装置控制器包括：运动收集部; 传感器控制部，被配置为基于所述移动信息来改变第二传感器测量所述被摄体中的照射区域的位置的第一时间间隔; 和照射控制部。 运动收集部分收集指示来自第一传感器的被摄体的运动的运动信息。 传感器控制单元基于移动信息改变第二传感器测量被摄体中的照射区域的位置的第一时间间隔。 照射控制部控制放射治疗装置，使得照射到照射区域的治疗射线基于位置而改变。

公开(公告)号：US20100215234A1

公开(公告)日：2010-08-26

申请号：US12557695

申请日：2009-09-11

申请人： Masahiro Yamada ,  Kunio Takahashi ,  Shuji Kaneko

发明人： Masahiro Yamada ,  Kunio Takahashi ,  Shuji Kaneko

IPC分类号： G06K9/00 ,  A61N5/00 ,  G06K9/68

CPC分类号： G06T7/55 ,  G06T7/32

摘要： In a control apparatus for a radiotherapy apparatus, each of a plurality of separation results indicates an objective portion template and a non-objective portion template. The separation result is calculated such that a difference between a first template production image and an image produced by superimposing an objective portion template in a position of a designated region on the non-objective portion template is small and a difference between the second template production image and an image produced by superimposing the objective portion template in a position of an assumption region, which is different from the designated region, on the non-objective portion template.

摘要翻译： 在放射治疗装置的控制装置中，多个分离结果中的每一个表示目标部分模板和非客观部分模板。 计算分离结果，使得第一模板生成图像与通过在非目标部分模板上的指定区域的位置叠加目标部分模板而产生的图像之间的差小，并且第二模板生成图像之间的差异 以及通过在非目标部分模板上将目标部分模板叠加在与指定区域不同的假定区域的位置而产生的图像。

公开(公告)号：US07436928B2

公开(公告)日：2008-10-14

申请号：US11707069

申请日：2007-02-16

申请人： Susumu Urano ,  Shuji Kaneko ,  Masahiro Yamada ,  Noriyuki Kawada

发明人： Susumu Urano ,  Shuji Kaneko ,  Masahiro Yamada ,  Noriyuki Kawada

IPC分类号： A61N5/10

CPC分类号： A61N5/1049 ,  A61N5/1065 ,  A61N5/1069 ,  A61N2005/1061 ,  A61N2005/1062

摘要： A radiotherapy device control apparatus includes: a template matching section; an affected area position calculating section; and an irradiation position control section. The radiotherapy device control apparatus controls a radiotherapy device. The radiotherapy device includes: a therapeutic radiation irradiation device radiating therapeutic radiation, and an imager generating an imager image of a subject by using radiation transmitted through the subject. The template matching section calculates degree of coincidence when a pattern matching is executed on the imager image with a plurality of image templates in which positional relations between an object area and a non-object area of the subject are different, and selects a specified image template having the degree of coincidence within a predetermined range from the plurality of image templates. The affected area position calculating section calculates a position of the object area by using the specified image template. The irradiation position control section judges whether a relative position of the object area with respect to the therapeutic radiation irradiation device. The irradiation position control section moves one of the therapeutic radiation irradiation device and a couch with the subject by using a drive device provided with the radiotherapy device such that the object area is irradiated with the therapeutic radiation.

摘要翻译： 放射治疗装置控制装置包括：模板匹配部; 受影响区位置计算部; 和照射位置控制部。 放射治疗装置控制装置控制放射治疗装置。 放射线治疗装置包括：放射治疗性放射线的治疗用放射线照射装置，以及通过使用通过被检体传播的辐射而产生被检体的成像器图像的成像器。 模板匹配部分计算在成像器图像上执行与匹配对象区域和对象区域之间的位置关系不同的多个图像模板的图案匹配时的一致度，并选择指定的图像模板 具有从多个图像模板的预定范围内的重合度。 受影响区域位置计算部分通过使用指定的图像模板来计算对象区域的位置。 照射位置控制部判断对象区域相对于治疗用放射线照射装置的相对位置。 照射位置控制部通过使用设置有放射线治疗装置的驱动装置使被治疗放射线照射装置和与被检体的沙发之间移动，使得对象区域被照射治疗性放射线。

公开(公告)号：US20080197304A1

公开(公告)日：2008-08-21

申请号：US11826964

申请日：2007-07-19

申请人： Susumu Urano ,  Shuji Kaneko ,  Seinoshin Hamanaka

发明人： Susumu Urano ,  Shuji Kaneko ,  Seinoshin Hamanaka

IPC分类号： H01J29/02

CPC分类号： A61N5/10 ,  A61N5/1081 ,  A61N2005/105 ,  A61N2005/1061

摘要： An object of the invention is to provide a medical device which can perform treatment and diagnosis without causing a sense of unease to the patient. The invention includes a substantially ring-shaped support frame provided in such a manner that a central axis through which an isocenter passes is disposed substantially horizontally; a substantially ring-shaped moving gantry which slides relative to the support frame and which has an opening at the isocenter side thereof; a radiation emitter configured to emit a beam towards the isocenter; and a protective cover which covers the radiation emitter and an inner circumferential side of the moving gantry and which moves together with the moving gantry.

摘要翻译： 本发明的目的是提供一种能够进行治疗和诊断而不会对患者造成不安感的医疗装置。 本发明包括基本上环形的支撑框架，其以等角点穿过的中心轴基本上水平地设置的方式设置; 基本上是环形的移动台架，其相对于支撑框架滑动，并且在其等角点侧具有开口; 辐射发射器被配置为朝向等角点发射光束; 以及保护盖，其覆盖所述辐射发射器和所述移动台架的内周侧，并与所述移动台架一起移动。

公开(公告)号：US20060009470A1

公开(公告)日：2006-01-12

申请号：US11228325

申请日：2005-09-19

申请人： Shuji Kaneko ,  Nobuya Matsuoka

发明人： Shuji Kaneko ,  Nobuya Matsuoka

IPC分类号： A61K31/4965

CPC分类号： G01N33/6872 ,  A61K31/495 ,  G01N33/5008 ,  G01N33/502

摘要： The present invention provides a method of specifically potentiating an N-type Ca2+ channel activity, which includes administering, to a subject, a compound of the following formula (I): wherein R1 is lower alkyl, aryl, ar(lower)alkoxy or a heterocyclic group, the above groups being optionally substituted by halogen, R2 is hydrogen atom or lower alkyl, R3 is cyclo(lower)alkyl, aryl or ar(lower)alkyl, the above groups being optionally substituted by halogen, A is —CO—, —SO2— or lower alkylene, and Y shows —CO—, —SO2— or —CONH— (compound (I)), a salt thereof, a prodrug thereof or a solvate thereof; a method for the prophylaxis or treatment of brain disorders such as dementia and amnesia, which includes such administration; and a screening method particularly useful for screening a compound having a similar effect as compound (I).

摘要翻译： 本发明提供了一种特异性增强N型Ca 2+通道活性的方法，其包括向受试者施用下式（I）的化合物：其中R 1 低级烷基，芳基，芳（低级）烷氧基或杂环基，上述基团任选被卤素取代，R 2是氢原子或低级烷基，R 3 烷基，芳基或芳（低级）烷基，上述基团任选被卤素取代，A是-CO - ， - SO 2 - 或低级亚烷基，和 Y表示-CO - ， - SO 2 - 或-CONH-（化合物（I）），其盐，前体药物或其溶剂合物; 一种预防或治疗诸如痴呆和遗忘症的脑疾病的方法，其包括这种给药; 以及特别可用于筛选化合物（I）具有相似作用的化合物的筛选方法。