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    Method and apparatus for controlled instrumentation of particles with a filter device
    22.
    发明授权
    Method and apparatus for controlled instrumentation of particles with a filter device 失效
    用过滤装置控制颗粒的仪器的方法和装置

    公开(公告)号：US6010909A

    公开(公告)日：2000-01-04

    申请号：US61928

    申请日：1993-05-13

    Applicant: Stanley N. Lapidus

    Inventor： Stanley N. Lapidus

    IPC: C12M1/12 ,  C12M1/26 ,  C12M1/34 ,  G01N1/28 ,  G01N15/02 ,  G01N15/06

    CPC classification number: C12M41/36 ,  G01N15/0272 ,  G01N1/2813 ,  G01N1/4077 ,  G01N2015/0662 ,  Y10T436/25375 ,  Y10T436/255

    Abstract: A method and apparatus for the controlled instrumentation processing of cells and other particles with a filter device measures a parameter of the flow through the filter device of a fluid carrying the particles. A measure of the change of fluid flow through the filter device yields desired information for quantizing the particles and for quantizing the obstruction of the filter device by the particles. The method and apparatus typically operate automatically. Cytological test methods and instruments can employ the invention to quantize and to collect cells.

    Abstract translation: 用于过滤装置的细胞和其它颗粒的受控仪器处理的方法和装置测量通过过滤装置的流过携带颗粒的流体的参数。 通过过滤装置的流体流量变化的量度产生用于量化颗粒的期望信息，并用于量化颗粒对过滤装置的阻塞。 该方法和装置通常自动运行。 细胞学测试方法和仪器可以采用本发明来量化和收集细胞。

    Methods for the detection of loss of heterozygosity
    24.
    发明授权
    Methods for the detection of loss of heterozygosity 失效
    检测杂合性丧失的方法

    公开(公告)号：US5928870A

    公开(公告)日：1999-07-27

    申请号：US876857

    申请日：1997-06-16

    Applicant: Stanley N. Lapidus ,  Anthony P. Shuber

    Inventor： Stanley N. Lapidus ,  Anthony P. Shuber

    IPC: C12Q1/68

    CPC classification number: C12Q1/6827

    Abstract: Methods are provided for detecting loss of heterozygosity in a nucleic acid sample. These methods are particularly useful for identifying individuals with gene mutations indicative of early colorectal cancer.

    Abstract translation: 提供了用于检测核酸样品中杂合性丧失的方法。 这些方法对于识别具有指示早期结肠直肠癌的基因突变的个体特别有用。

    Vision inspection system
    27.
    发明授权
    Vision inspection system 失效
    视力检查系统

    公开(公告)号：US4581762A

    公开(公告)日：1986-04-08

    申请号：US572570

    申请日：1984-01-19

    Applicant: Stanley N. Lapidus ,  Joseph J. Dziezanowski ,  Seymour A. Friedel ,  Michael P. Greenberg

    Inventor： Stanley N. Lapidus ,  Joseph J. Dziezanowski ,  Seymour A. Friedel ,  Michael P. Greenberg

    IPC: G06T7/00 ,  G06K9/46

    CPC classification number: G06T7/001 ,  G06T2207/30164

    Abstract: A vision inspection system operable with foreground illumination provides user identification of selected regions of a known object for later comparison to an unknown object. A gray scale pixel array of each selected region is processed for edges and this processed data array is stored as a template for each region. Gray scale illumination data from larger corresponding areas of the unknown object are processed for edges to form gradient maps. The first template is iteratively compared to the first gradient map. A correlation value greater than a threshold value causes the system to examine the second and possibly third gradient maps on the unknown object. Distance and angular relationships of the regions are used to both identify and orient the object under test. Once the unknown object is identified and its orientation determined, various visual attributes and measurements of the object can be determined through use of visual tools.

    Abstract translation: 可用前景照明操作的视觉检查系统提供用户识别已知对象的选定区域，以便稍后与未知对象进行比较。 对于边缘处理每个所选区域的灰度像素阵列，并且将该处理的数据阵列存储为每个区域的模板。 针对未知对象的较大对应区域的灰度照明数据进行边缘处理，形成梯度图。 将第一个模板与第一个梯度图进行迭代比较。 大于阈值的相关值导致系统检查未知对象上的第二和第三梯度图。 区域的距离和角度关系用于识别和定向被测物体。 一旦识别出未知对象并确定其方向，就可以通过使用可视化工具确定对象的各种视觉属性和测量。

    METHODS AND DEVICES FOR COLLECTING BLOOD
    28.
    发明申请
    METHODS AND DEVICES FOR COLLECTING BLOOD 审中-公开

    公开(公告)号：US20190053747A1

    公开(公告)日：2019-02-21

    申请号：US16107574

    申请日：2018-08-21

    Applicant: Stanley N. Lapidus ,  Anthony P. Shuber

    Inventor： Stanley N. Lapidus ,  Anthony P. Shuber

    IPC: A61B5/15 ,  C12Q1/6806

    Abstract: The invention provides methods and devices for drawing blood, in which the blood collected into a container closely resembles the blood as it existed before collection (i.e., as it existed in vivo). In some embodiments this may be achieved by modulating a flow rate of blood into the collection container in order to preserve the integrity of the blood. By modulating the flow rate of the blood, shear forces acting on cells and cellular components in the blood are reduced. This preserves the integrity of such cells and cellular components and facilitates more accurate detection and analysis of low-abundance analytes.

    SYSTEM AND METHOD FOR ANALYSIS AND PRESENTATION OF GENOMIC DATA
    29.
    发明申请
    SYSTEM AND METHOD FOR ANALYSIS AND PRESENTATION OF GENOMIC DATA 审中-公开
    用于分析和介绍基因数据的系统和方法

    公开(公告)号：US20090240441A1

    公开(公告)日：2009-09-24

    申请号：US12052492

    申请日：2008-03-20

    Applicant: Stanley N. Lapidus

    Inventor： Stanley N. Lapidus

    IPC: G06F19/00

    CPC classification number: G16B50/00 ,  G16B20/00

    Abstract: A method for analyzing genomic data that includes obtaining genomic sequence information from an anonymous individual, processing the information via a secure computerized algorithm, and presenting phenotypic information to the individual based upon the genomic sequence information.

    Abstract translation: 一种用于分析基因组数据的方法，所述方法包括从匿名个体获得基因组序列信息，经由安全的计算机化算法处理所述信息，以及基于所述基因组序列信息向所述个体呈现表型信息。

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