专利检索 ap:("Steven Harper" OR "Vincenzo Summa" OR "Nigel J. Liverton" OR "John A. McCauley" OR "John W. Butcher" OR "Marcello Di Filippo" OR "Maria Emilia Di Francesco" OR "Marco Ferrara" OR "Joseph J. Romano" OR "Michael T. Rudd") AND inv:"Maria Emilia Di Francesco" 第 3 页

21.

发明申请
AMINOPYRIMIDINES AS SYK INHIBITORS 有权

公开(公告)号：US20120277192A1

公开(公告)日：2012-11-01

申请号：US13516455

申请日：2010-12-15

申请人： Michael D. Altman , Brian M. Andresen , Kenneth L. Arrington , Sathesh Bhat , Jason Burch , Kaleen Konrad Childers , Bernard Cote , Maria Emilia Di Francesco , Anthony Donofrio , Kristina Dupont-Gaudet , John Michael Ellis , Christian Fischer , Jean-Francois Fournier , Jacques Yves Gauthier , Jonathan Grimm , Daniel Guay , David Joseph Guerin , Andrew M. Haidle , Solomon Kattar , Sandra Lee Knowles , Chaomin Li , Jongwon Lim , Michelle R. Machacek , Matthew L. Maddess , Alan B. Northrup , Brendan M. O'Boyle , Ryan D. Otte , Alessia Petrocchi , Michael H. Reutershan , Joel S. Robichaud , Eric Romeo , Adam J. Schell , Tony Siu , Kerrie B. Spencer , Brandon M. Taoka , B. Wesley Trotter , Hyun Chong Woo , Hua Zhou

发明人： Michael D. Altman , Brian M. Andresen , Kenneth L. Arrington , Sathesh Bhat , Jason Burch , Kaleen Konrad Childers , Bernard Cote , Maria Emilia Di Francesco , Anthony Donofrio , Kristina Dupont-Gaudet , John Michael Ellis , Christian Fischer , Jean-Francois Fournier , Jacques Yves Gauthier , Jonathan Grimm , Daniel Guay , David Joseph Guerin , Andrew M. Haidle , Solomon Kattar , Sandra Lee Knowles , Chaomin Li , Jongwon Lim , Michelle R. Machacek , Matthew L. Maddess , Alan B. Northrup , Brendan M. O'Boyle , Ryan D. Otte , Alessia Petrocchi , Michael H. Reutershan , Joel S. Robichaud , Eric Romeo , Adam J. Schell , Tony Siu , Kerrie B. Spencer , Brandon M. Taoka , B. Wesley Trotter , Hyun Chong Woo , Hua Zhou

IPC分类号： A61K31/506 , A61K31/55 , A61K31/554 , A61K31/551 , A61P35/00 , C07D417/14 , C07F9/6539 , C07D417/12 , A61P19/02 , A61P11/06 , A61K31/675 , A61K31/5377

CPC分类号： C07D417/12 , C07D417/14 , C07D451/06 , C07D471/04 , C07D471/08 , C07D487/04 , C07D491/08 , C07D495/04 , C07F9/65583

摘要： The present invention provides novel pyrimidine amines of formula (I) which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis.

22.

发明申请
ANTIVIRAL AGENTS 审中-公开
标题翻译：抗病毒剂

公开(公告)号：US20120010164A1

公开(公告)日：2012-01-12

申请号：US13145456

申请日：2010-01-19

申请人： Vincenzo Surnma , Maria Emilia Di Francesco , Marco Pompei

发明人： Vincenzo Surnma , Maria Emilia Di Francesco , Marco Pompei

IPC分类号： A61K31/7064 , A61P31/14 , A61K31/7076 , C07H19/14 , C07H19/19

CPC分类号： C07H19/173 , C07H19/14

摘要： Compounds of structural formula (I): and pharmaceutically acceptable salts thereof; as defined herein, are described for use in the prevention and/or treatment of HCV infections. Novel compounds of the formula (I) and pharmaceutical formulations containing them are also described.

摘要翻译： 结构式（I）的化合物及其药学上可接受的盐; 描述用于预防和/或治疗HCV感染。还描述了新的式（I）化合物和含有它们的药物制剂。