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    Methods and compositions for the treatment of lupus using clofarabine
    22.
    发明申请
    Methods and compositions for the treatment of lupus using clofarabine 审中-公开
    使用氯法拉滨治疗狼疮的方法和组合物

    公开(公告)号：US20060135463A1

    公开(公告)日：2006-06-22

    申请号：US10529520

    申请日：2003-09-25

    Applicant: Christopher Wood ,  Stuart Smith

    Inventor： Christopher Wood ,  Stuart Smith

    IPC: A61K31/7076

    CPC classification number: A61K31/7076 ,  A61K31/34

    Abstract: This invention relates to methods of treating or preventing lupus comprising the administration of clofarabine or a pharmaceutically acceptable salt, hydrate, solvate or clathrate thereof to a patient in need of such treatment. The invention further relates to methods of treating or preventing lupus comprising the administration of clofarabine or a pharmaceutically acceptable salt, hydrate, solvate or clathrate thereof and an additional therapeutic agent to a patient in need of such treatment.

    Abstract translation: 本发明涉及治疗或预防狼疮的方法，其包括向需要这种治疗的患者施用氯法拉滨或其药学上可接受的盐，水合物，溶剂合物或包合物。 本发明还涉及治疗或预防狼疮的方法，其包括向需要这种治疗的患者施用氯法拉滨或其药学上可接受的盐，水合物，溶剂化物或包合物和额外的治疗剂。

    Symmetric spindle design
    24.
    发明申请
    Symmetric spindle design 失效
    对称主轴设计

    公开(公告)号：US20050242258A1

    公开(公告)日：2005-11-03

    申请号：US11106400

    申请日：2005-04-14

    Applicant: Marcin Bauza ,  Stuart Smith ,  Shane Woody

    Inventor： Marcin Bauza ,  Stuart Smith ,  Shane Woody

    IPC: F16C17/10 ,  F16C25/02 ,  G11B5/54

    CPC classification number: F16C17/10 ,  F16C23/043 ,  F16C25/02

    Abstract: A symmetric ultra-precision spindle design in which all forces of constraint are, within the tolerances of manufacturing and assembly processes, symmetrically arranged about its axis. Additionally this design may require little or no external power other than the forces to rotate the spindle.

    Abstract translation: 对称的超精密主轴设计，其中所有约束力都在制造和组装过程的公差内，围绕其轴线对称排列。 另外，除了旋转主轴的力之外，该设计可能需要很少的或没有外部的力量。

    Mandrel and method for manufacturing composite structures
    25.
    发明申请
    Mandrel and method for manufacturing composite structures 有权
    心轴和制造复合结构的方法

    公开(公告)号：US20050051262A1

    公开(公告)日：2005-03-10

    申请号：US10657969

    申请日：2003-09-09

    Applicant: Dave Erickson ,  Panagiotis George ,  Ryan Mortensen ,  Stuart Smith

    Inventor： Dave Erickson ,  Panagiotis George ,  Ryan Mortensen ,  Stuart Smith

    IPC: B29C70/34 ,  B29C70/54 ,  B32B37/14 ,  B32B31/26

    CPC classification number: B32B37/146 ,  B29C70/342 ,  B29C70/543

    Abstract: An apparatus and method for retaining composite structures, such as composite honeycomb structures, during manufacture are provided. The composite structure is cured on a mandrel that defines a layup surface with a grip feature. The grip feature is configured to engage the composite structure during manufacture and retain the structure in a predetermined configuration. A film adhesive can be provided between the grip feature and a tiedown ply that extends from the composite structure.

    Abstract translation: 提供了一种用于在制造期间保持诸如复合蜂窝结构的复合结构的装置和方法。 复合结构在限定具有抓握特征的铺层表面的心轴上固化。 把手特征构造成在制造过程中与复合结构接合，并将结构保持在预定的构型。 可以在把手特征和从复合结构延伸的被捆绑层之间提供胶粘剂。

    Electronic expansion valve (EEV) controller
    28.
    发明授权
    Electronic expansion valve (EEV) controller 有权

    公开(公告)号：US11300342B2

    公开(公告)日：2022-04-12

    申请号：US16830250

    申请日：2020-03-25

    Applicant: Barry Lee Dusenbury ,  Stuart Smith

    Inventor： Barry Lee Dusenbury ,  Stuart Smith

    IPC: F25B49/02 ,  H05K7/14 ,  H05K3/30 ,  H05K5/00 ,  F25B41/34

    Abstract: An electronic expansion valve (EEV) controller allows a user to drive the stepper motor of EEVs. Thus, the EEVs toggle between an open position or a closed position. The EEV controller includes a housing, a portable power supply, a motor driver printed circuit board (PCB), a power switch, a directional switch, and a motor connector. The housing is used to protect and hold in place the motor driver PCB, the portable power supply, the power switch, the directional switch, and the motor connector. The portable power supply is used to provide electrical energy to the motor driver PCB and to the stepper motor of EEVs through the motor connector. The power switch allows a user to manually turn on or off the EEV controller and the stepper motor. The directional switch is used to toggle the stepper motor between a clockwise rotation or a counter-clockwise rotation.

    OPTICAL INSTRUMENTS
    29.
    发明申请
    OPTICAL INSTRUMENTS 审中-公开
    光学仪器

    公开(公告)号：US20140085628A1

    公开(公告)日：2014-03-27

    申请号：US14111306

    申请日：2012-04-13

    Applicant: Norman McMillan ,  Martina O'Neill ,  Kevin Arthure ,  Stuart Smith

    Inventor： Norman McMillan ,  Martina O'Neill ,  Kevin Arthure ,  Stuart Smith

    IPC: G01N21/01

    CPC classification number: G01N21/01 ,  G01N21/03 ,  G01N2021/035

    Abstract: An optical instrument (10) has a drop-supporting surface for receiving a droplet (98) of liquid with a cover (16) mounted on the housing (12) which receives a light source and provides communication between the light source (114) and the inner surface of the cover. A loading aperture (24) extending through the cover permits access to the drophead when the cover is in a first rotational loading position, and the cover may be rotated to a measurement position in which the light source is positioned to illuminate the drop-supporting surface. A positioning mechanism provided between the cover an the housing engages the cover when it reaches the measurement position and thereby ensures that the light source and drop-supporting surface are maintained in fixed spaced-apart relationship.

    Abstract translation: 光学仪器（10）具有用于接收具有安装在壳体（12）上的盖（16）的液体的液滴（98）的液滴支撑表面，所述盖（16）接收光源并且提供光源（114）和 盖的内表面。 当盖处于第一旋转加载位置时，延伸穿过盖的加载孔（24）允许进入液滴头，并且盖可以旋转到测量位置，在该位置中光源被定位以照亮液滴支撑表面 。 设置在所述盖之间的定位机构，当所述壳体到达所述测量位置时，所述壳体与所述盖接合，从而确保所述光源和所述液滴支撑表面保持为固定的间隔关系。

    Microvolume analysis system
    30.
    发明授权
    Microvolume analysis system 有权
    微体积分析系统

    公开(公告)号：US08681340B2

    公开(公告)日：2014-03-25

    申请号：US12227266

    申请日：2007-05-10

    Applicant: Norman McMillan ,  Stuart Smith ,  Martina O'Neill ,  Michael Baker

    Inventor： Norman McMillan ,  Stuart Smith ,  Martina O'Neill ,  Michael Baker

    IPC: G01B11/02

    CPC classification number: G01N21/03 ,  G01N15/1463 ,  G01N21/31 ,  G01N2013/0241 ,  G01N2021/035 ,  G01N2021/6417 ,  G01N2035/00237

    Abstract: An analyzer comprising a source of electromagnetic radiation, a detector for said radiation and a drophead comprising a surface which is adapted to receive a drop of liquid to be tested, the drophead being positioned in use relative to the source and detector to illuminate a drop received thereon and to cause an interaction in the path of the electromagnetic radiation between the source and detector, characterized in that said surface of said drophead is dimensioned to constrain the drop to adopt a shape which is dominated more by surface tension forces than by gravitational forces.

    Abstract translation: 一种分析器，包括电磁辐射源，用于所述辐射的检测器和一个液滴头，其包括适于接收一滴待测试液体的表面，所述液滴头相对于所述源和检测器定位在使用中以照亮所接收的液滴 并且在源和检测器之间的电磁辐射的路径中引起相互作用，其特征在于，所述液滴头的所述表面的尺寸被设计成约束液滴，以采用更多地受到表面张力而不是重力所主导的形状。

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