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公开(公告)号：US08940758B2
公开(公告)日：2015-01-27
申请号：US13944370
申请日：2013-07-17
Applicant: Takeda Pharmaceutical Company Limited
Inventor： Takahiko Taniguchi , Masato Yoshikawa , Kasei Miura , Tomoaki Hasui , Eiji Honda , Keisuke Imamura , Makoto Kamata , Haruhi Ando
IPC: A61K31/4353 , A61K31/437 , A61K31/4355
CPC classification number: A61K31/4353 , A61K31/4355 , A61K31/437 , A61K31/4427 , A61K31/4439 , A61K31/444 , A61K31/4985 , A61K31/5025 , A61K31/519 , A61K31/52 , A61K31/522 , A61K31/551 , C07D401/14 , C07D403/04 , C07D403/14 , C07D413/14 , C07D471/04 , C07D471/14 , C07D473/00 , C07D473/28 , C07D487/04 , C07D495/04 , C07D498/04 , C07D498/08 , C07D519/00 , C07F7/10
Abstract: The present invention provides a compound which has the effect of PDE inhibition, and which is useful as an agent for preventing or treating schizophrenia. The compound is represented by the formula (I): wherein the symbols are defined in the specification.
Abstract translation: 本发明提供具有PDE抑制作用的化合物，其可用作预防或治疗精神分裂症的药剂。 化合物由式（I）表示：其中符号在说明书中定义。
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公开(公告)号：US08871766B2
公开(公告)日：2014-10-28
申请号：US13944042
申请日：2013-07-17
Applicant: Takeda Pharmaceutical Company Limited
Inventor： Tatsuki Koike , Masato Yoshikawa , Haruhi Ando , William John Farnaby
IPC: A61K31/50 , A61K31/501 , C07D405/14 , C07D413/14 , C07D413/10 , C07D401/10 , C07D498/08 , C07D401/14 , C07D417/14
CPC classification number: C07D498/08 , C07D401/10 , C07D401/14 , C07D405/10 , C07D405/14 , C07D413/10 , C07D413/14 , C07D417/14
Abstract: The present invention provides a compound useful as an agent for the prophylaxis or treatment of neurodegenerative disease and the like, or a salt thereof.The present invention relates to a compound represented by the formula wherein each symbol is as defined in the specification, or a salt thereof.
Abstract translation: 本发明提供可用作预防或治疗神经变性疾病等的药剂或其盐。 本发明涉及由下式表示的化合物，其中每个符号如说明书中所定义，或其盐。
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公开(公告)号：US08865717B2
公开(公告)日：2014-10-21
申请号：US13944000
申请日：2013-07-17
Applicant: Takeda Pharmaceutical Company Limited
Inventor： Tatsuki Koike , Masato Yoshikawa , Haruhi Ando , William John Farnaby
IPC: A61K31/50 , A61K31/501 , C07D413/14 , C07D417/14 , C07D413/10 , C07D401/10 , C07D401/14 , C07D498/08 , C07D405/14
CPC classification number: C07D498/08 , C07D401/10 , C07D401/14 , C07D405/10 , C07D405/14 , C07D413/10 , C07D413/14 , C07D417/14
Abstract: The present invention provides a compound useful as an agent for the prophylaxis or treatment of neurodegenerative disease and the like, or a salt thereof.The present invention relates to a compound represented by the formula wherein each symbol is as defined in the specification, or a salt thereof.
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公开(公告)号：US08648079B2
公开(公告)日：2014-02-11
申请号：US13633995
申请日：2012-10-03
Applicant: Takeda Pharmaceutical Company Limited
Inventor： Tatsuki Koike , Masato Yoshikawa , Haruhi Ando , William John Farnaby
IPC: A61K31/50 , A61K31/501
CPC classification number: C07D498/08 , C07D401/10 , C07D401/14 , C07D405/10 , C07D405/14 , C07D413/10 , C07D413/14 , C07D417/14
Abstract: The present invention provides a compound useful as an agent for the prophylaxis or treatment of neurodegenerative disease and the like, or a salt thereof.The present invention relates to a compound represented by the formula wherein each symbol is as defined in the specification, or a salt thereof.
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