公开(公告)号：USRE44872E1

公开(公告)日：2014-04-29

申请号：US13542308

申请日：2012-07-05

申请人： Toshiyuki Takasu ,  Shuichi Sato ,  Masashi Ukai ,  Tatsuya Maruyama ,  Masayuki Shibasaki

发明人： Toshiyuki Takasu ,  Shuichi Sato ,  Masashi Ukai ,  Tatsuya Maruyama ,  Masayuki Shibasaki

IPC分类号： A61K31/426 ,  A61P13/10

摘要： (R)-2-(2-aminothiazol-4-yl)-4′-[2-[(2-hydroxy-2-phenylethyl)amino]ethyl]acetic acid anilide or its salt shows a potent bladder relaxation effect in “isolated rat bladder smooth muscle relaxation test”, dose-dependently lowers the contraction frequency of rhythmic bladder contractions in “rat rhythmic bladder contraction measurement test” and, moreover, prolongs the urination intervals in “urination functions measurement test on cyclophosphamide-induced overactive bladder model rat”. Owing to these effects, the above compound is useful as a remedy for ovaractive bladder.

摘要翻译： （R）-2-（2-氨基噻唑-4-基）-4' - [2 - [（2-羟基-2-苯乙基）氨基]乙基]乙酰苯胺或其盐在“ 孤立的大鼠膀胱平滑肌松弛试验“，在”大鼠节律性膀胱收缩测定试验“中剂量依赖性地降低了节律性膀胱收缩的收缩频率，此外，在”环磷酰胺诱导的膀胱过度活动膀胱模型的排尿功能测量试验“中延长了排尿间隔 鼠”。 由于这些效果，上述化合物可用作膀胱膀胱的补救剂。

公开(公告)号：US08196957B2

公开(公告)日：2012-06-12

申请号：US12591854

申请日：2009-12-03

申请人： Yoshiyuki Kubo ,  Tsutomu Teramura ,  Tatsuya Maruyama ,  Masafumi Ueda

发明人： Yoshiyuki Kubo ,  Tsutomu Teramura ,  Tatsuya Maruyama ,  Masafumi Ueda

IPC分类号： B60R21/16

CPC分类号： B60R21/2338 ,  B60R21/201 ,  B60R21/231 ,  B60R21/237 ,  B60R21/239 ,  B60R2021/23384

摘要： An airbag for protecting an occupant includes a panel forming the airbag and having an occupant counter surface with a head counter portion to face a head of the occupant when the airbag is inflated. A recess portion is formed in the head counter portion when the airbag is inflated. The airbag also includes a regulation member for regulating inflation of the head counter portion toward the occupant. The regulation member forms the recess portion by regulating inflation of the head counter portion toward the occupant upon inflation of the airbag. The regulation member is configured to release regulation after a predetermined time from a moment when the airbag starts inflation.

摘要翻译： 一种用于保护乘客的安全气囊包括形成气囊的面板，并且当气囊膨胀时，具有与乘员对面部分相对的乘员对面部分，以面对乘员的头部。 当气囊膨胀时，在头部对置部中形成有凹部。 安全气囊还包括用于调节头部对置部朝向乘员的膨胀的调节构件。 调节构件通过在气囊充气时调节头部对置部朝向乘员的充气而形成凹部。 所述调节部件构成为在从所述气囊开始膨胀的时刻起经过规定时间后释放调节。

公开(公告)号：US07982049B2

公开(公告)日：2011-07-19

申请号：US12007653

申请日：2008-01-14

申请人： Souichirou Kawazoe ,  Kenichirou Sakamoto ,  Yuji Awamura ,  Tatsuya Maruyama ,  Takayuki Suzuki ,  Kenichi Onda ,  Toshiyuki Takasu

发明人： Souichirou Kawazoe ,  Kenichirou Sakamoto ,  Yuji Awamura ,  Tatsuya Maruyama ,  Takayuki Suzuki ,  Kenichi Onda ,  Toshiyuki Takasu

IPC分类号： A61K31/426 ,  C07D277/40

CPC分类号： C07D277/40

摘要： To provide novel crystals useful as an ingredient for the production of a diabetes remedy. The invention is concerned with α-form crystal and β-form crystal of (R)-2-(2-aminothiazol-4-yl)-4′-[2-[(2-hydroxy-2-phenylethyl)amino]ethyl]acetanilide. The α-form crystal does not exhibit hygroscopicity and has stability such that it can be used as a medicine, and is useful for mass synthesis in the industrial production. The β-form crystal does not relatively exhibit hygroscopicity and is also useful as a production intermediate of the α-form crystal.

摘要翻译： 提供可用作糖尿病药物生产成分的新型晶体。 本发明涉及（R）-2-（2-氨基噻唑-4-基）-4' - [2 - [（2-羟基-2-苯基乙基）氨基] 乙基]乙酰苯胺。 α型结晶不具有吸湿性，稳定性高，可用作药物，可用于工业生产中的大规模合成。 该晶体不相对显示吸湿性，也可用作α型晶体的生产中间体。

公开(公告)号：US20080214633A1

公开(公告)日：2008-09-04

申请号：US12007653

申请日：2008-01-14

申请人： Souichirou Kawazoe ,  Kenichirou Sakamoto ,  Yuji Awamura ,  Tatsuya Maruyama ,  Takayuki Suzuki ,  Kenichi Onda ,  Toshiyuki Takasu

发明人： Souichirou Kawazoe ,  Kenichirou Sakamoto ,  Yuji Awamura ,  Tatsuya Maruyama ,  Takayuki Suzuki ,  Kenichi Onda ,  Toshiyuki Takasu

IPC分类号： A61K31/426 ,  A61P3/10

CPC分类号： C07D277/40

摘要： To provide novel crystals useful as an ingredient for the production of a diabetes remedy. The invention is concerned with α-form crystal and β-form crystal of (R)-2-(2-aminothiazol-4-yl)-4′-[2-[(2-hydroxy-2-phenylethyl)amino]ethyl]acetanilide. The α-form crystal does not exhibit hygroscopicity and has stability such that it can be used as a medicine, and is useful for mass synthesis in the industrial production. The β-form crystal does not relatively exhibit hygroscopicity and is also useful as a production intermediate of the α-form crystal.

摘要翻译： 提供可用作糖尿病药物生产成分的新型晶体。 本发明涉及（R）-2-（2-氨基噻唑-4-基）-4' - [2 - [（2-羟基-2-苯基乙基）氨基]乙基的α-晶型和β型晶体 ]乙酰苯胺。 α型晶体不具有吸湿性并且具有稳定性，使得其可以用作药物，并且可用于工业生产中的大量合成。 β型晶体不具有吸湿性，也可用作α型晶体的生产中间体。

公开(公告)号：US07342117B2

公开(公告)日：2008-03-11

申请号：US10494018

申请日：2002-10-20

申请人： Souichirou Kawazoe ,  Kenichirou Sakamoto ,  Yuji Awamura ,  Tatsuya Maruyama ,  Takayuki Suzuki ,  Kenichi Onda ,  Toshiyuki Takasu

发明人： Souichirou Kawazoe ,  Kenichirou Sakamoto ,  Yuji Awamura ,  Tatsuya Maruyama ,  Takayuki Suzuki ,  Kenichi Onda ,  Toshiyuki Takasu

IPC分类号： C07D277/40

CPC分类号： C07D277/40

摘要： To provide novel crystals useful as an ingredient for the production of a diabetes remedy. The invention is concerned with α-form crystal and β-form crystal of (R)-2-(2-aminothiazol-4-yl)-4′-[2-[(2-hydroxy-2-phenyleth-yl)amino]ethyl]acetanilide. The α-form crystal does not exhibit hygroscopicity and has stability such that it can be used as a medicine, and is useful for mass synthesis in the industrial production. The β-form crystal does not relatively exhibit hygroscopicity and is also useful as a production intermediate of the α-form crystal.

摘要翻译： 提供可用作糖尿病药物生产成分的新型晶体。 本发明涉及（R）-2-（2-氨基噻唑-4-基）-4' - [2 - [（2-羟基-2-苯基] - 基）氨基的α-晶型和β型晶体 乙基]乙酰苯胺。 α型晶体不具有吸湿性并且具有稳定性，使得其可以用作药物，并且可用于工业生产中的大量合成。 β型晶体不具有吸湿性，也可用作α型晶体的生产中间体。

公开(公告)号：US20060115540A1

公开(公告)日：2006-06-01

申请号：US10534290

申请日：2003-11-04

申请人： Toshiyuki Takasu ,  Shuichi Sato ,  Masashi Ukai ,  Tatsuya Maruyama

发明人： Toshiyuki Takasu ,  Shuichi Sato ,  Masashi Ukai ,  Tatsuya Maruyama

IPC分类号： A61K33/00

CPC分类号： A61K31/426 ,  C07D277/40

摘要： (R)-2-(2-aminothiazol-4-yl)-4′-[2-[(2-hydroxy-2-phenylethyl)amino]ethyl]acetic acid anilide or its salt shows a potent bladder relaxation effect in “isolated rat bladder smooth muscle relaxation test”, dose-dependently lowers the contraction frequency of rhythmic bladder contractions in “rat rhythmic bladder contraction measurement test” and, moreover, prolongs the urination intervals in “urination functions measurement test on cyclophosphamide-induced overactive bladder model rat”. Owing to these effects, the above compound is useful as a remedy for ovaractive bladder.

摘要翻译： （R）-2-（2-氨基噻唑-4-基）-4' - [2 - [（2-羟基-2-苯乙基）氨基]乙基]乙酰苯胺或其盐在“ 孤立的大鼠膀胱平滑肌松弛试验“，在”大鼠节律性膀胱收缩测定试验“中剂量依赖性地降低了节律性膀胱收缩的收缩频率，此外，在”环磷酰胺诱导的膀胱过度活动膀胱模型的排尿功能测量试验“中延长了排尿间隔 鼠”。 由于这些效果，上述化合物可用作膀胱膀胱的补救剂。

公开(公告)号：US08613468B2

公开(公告)日：2013-12-24

申请号：US13162924

申请日：2011-06-17

申请人： Tatsuya Maruyama

发明人： Tatsuya Maruyama

IPC分类号： B60R21/261

CPC分类号： B60R21/2171 ,  B60R21/23138 ,  B60R21/261 ,  B60R2021/2612

摘要： This disclosure discloses a side-collision airbag apparatus comprising: a side-collision airbag; an inflator configured to inject gas; and an inflator holder configured to support the inflator; wherein: the inflator comprises: an inflator main body portion that is substantially cylindrical in shape and produces the gas; an injecting portion that protrudes from a tip end of the inflator main body portion; and a clasp portion positioned between the inflator main body portion and the injecting portion; the inflator holder comprises: a holding portion configured to hold the inflator; and a diffuser portion having a diffuser tube that has a cross-section substantially elliptical in shape; and the diffuser tube comprises a contraction opening at an end portion in an injection direction of the gas, and is provided so that an end portion opposite the injection direction of the gas faces to the radial outer peripheral side of the clasp portion.

摘要翻译： 本发明公开了一种侧碰撞气囊装置，包括：侧碰撞气囊; 构造成喷射气体的充气器; 以及构造成支撑所述充气机的充气器保持器; 其中：所述充气机包括：充气机主体部分，其基本上为圆柱形并产生气体; 从所述充气机主体部的前端突出的注入部; 以及定位在充气机主体部分和注射部分之间的扣环部分; 所述充气机支架包括：保持部，其构造成保持所述充气机; 以及扩散器部分，其具有截面基本上椭圆形的扩散管; 并且扩散管包括在气体的喷射方向的端部处的收缩开口，并且设置成使得与气体的喷射方向相反的端部面向扣环部分的径向外周侧。

公开(公告)号：US07750029B2

公开(公告)日：2010-07-06

申请号：US10534290

申请日：2003-11-04

申请人： Toshiyuki Takasu ,  Shuichi Sato ,  Masashi Ukai ,  Tatsuya Maruyama

发明人： Toshiyuki Takasu ,  Shuichi Sato ,  Masashi Ukai ,  Tatsuya Maruyama

IPC分类号： A61K31/426 ,  A61P13/10

CPC分类号： A61K31/426 ,  C07D277/40

摘要： (R)-2-(2-aminothiazol-4-yl)-4′-[2-[(2-hydroxy-2-phenylethyl)amino]ethyl]acetic acid anilide or its salt shows a potent bladder relaxation effect in “isolated rat bladder smooth muscle relaxation test”, dose-dependently lowers the contraction frequency of rhythmic bladder contractions in “rat rhythmic bladder contraction measurement test” and, moreover, prolongs the urination intervals in “urination functions measurement test on cyclophosphamide-induced overactive bladder model rat”. Owing to these effects, the above compound is useful as a remedy for ovaractive bladder.

摘要翻译： （R）-2-（2-氨基噻唑-4-基）-4' - [2 - [（2-羟基-2-苯乙基）氨基]乙基]乙酰苯胺或其盐在“ 孤立的大鼠膀胱平滑肌松弛试验“，在”大鼠节律性膀胱收缩测定试验“中剂量依赖性地降低了节律性膀胱收缩的收缩频率，此外，在”环磷酰胺诱导的膀胱过度活动膀胱模型的排尿功能测量试验“中延长了排尿间隔 鼠”。 由于这些效果，上述化合物可用作膀胱膀胱的补救剂。

公开(公告)号：US07501210B2

公开(公告)日：2009-03-10

申请号：US11696017

申请日：2007-04-03

申请人： Jiro Minabe ,  Tatsuya Maruyama ,  Katsunori Kawano ,  Shin Yasuda

发明人： Jiro Minabe ,  Tatsuya Maruyama ,  Katsunori Kawano ,  Shin Yasuda

IPC分类号： G03H1/02

CPC分类号： G11B7/25

摘要： In the present invention, a photosensitive layer of an optical recording medium includes a photo-responsive high-molecular compound comprising a photo-responsive group (e.g., an azobenzene derivative) which is geometrically isomerized by light radiation, and a liquid crystal linear mesogen group (e.g., a biphenyl derivative), wherein the photo-responsive group and the linear mesogen group are respectively bonded as side chains. The invention provides an optical recording medium enabling large scale recording by making the photosensitive layer thick without impairing recording characteristics. The photo-responsive high-molecular compound preferably comprises an aromatic ring on a main chain. Further, the photo-responsive high-molecular compound preferably comprises a structural unit which is capable of forming a liquid-crystalline or crystalline polymer and a structural unit which is capable of forming an amorphous polymer.

摘要翻译： 在本发明中，光记录介质的感光层包括光反应性高分子化合物，其包含通过光辐射几何异构化的光响应性基团（例如偶氮苯衍生物）和液晶线性介晶基 （例如联苯衍生物），其中光敏反应基团和线性介晶基团分别作为侧链键合。 本发明提供一种能够通过使光敏层厚而不损害记录特性而进行大规模记录的光记录介质。 光敏高分子化合物优选在主链上包含芳香环。 此外，光敏高分子化合物优选包含能够形成液晶或结晶聚合物的结构单元和能够形成无定形聚合物的结构单元。

公开(公告)号：US07154646B2

公开(公告)日：2006-12-26

申请号：US11411873

申请日：2006-04-27

申请人： Katsunori Kawano ,  Jiro Minabe ,  Tatsuya Maruyama ,  Shin Yasuda ,  Norie Matsui ,  Tsutomu Ishii ,  Kazuhiro Hama

发明人： Katsunori Kawano ,  Jiro Minabe ,  Tatsuya Maruyama ,  Shin Yasuda ,  Norie Matsui ,  Tsutomu Ishii ,  Kazuhiro Hama

IPC分类号： G03H1/12

CPC分类号： G11B7/245 ,  G03H2222/31 ,  G11B7/0065 ,  G11B7/128 ,  G11B7/1353 ,  G11B7/1356 ,  G11B7/1369 ,  G11B7/2467 ,  G11B7/25 ,  G11B7/2531 ,  G11B7/2533 ,  G11B7/2534 ,  G11B7/2535

摘要： An optical recording/reproducing apparatus having excellent resistance against vibration and noise. In recording, coherent light is polarization-modulated with a spatial light modulator to generate signal light and reference light whose polarization directions are crossed at right angles. The signal light permeates a polarizing beam splitter, and is incident to a quarter wavelength plate. The reference light passes through a passing hole, is diffused by a light diffuser and is incident to the quarter wavelength plate. The reference and signal light are converted into circularly polarized light which revolve in directions opposite to each other and condensed by a condenser lens, and then a predetermined area of an optical recording medium is irradiated with the reference and signal light. Thus, the reference and signal light are generated by modulating the incident light from the same light source and are coaxially incident to the polarizing beam splitter.

摘要翻译： 具有优异的耐振动和噪音的光学记录/重放装置。 在记录中，相干光利用空间光调制器进行偏振调制，以产生信号光和偏振方向以直角交叉的参考光。 信号光透过偏振分束器，并入射到四分之一波长板上。 参考光通过通孔，被光扩散器扩散并入射到四分之一波长板。 参考信号光和信号光被转换为以相反方向旋转并由聚光透镜聚光的圆偏振光，然后用参考信号光照射光记录介质的预定区域。 因此，通过调制来自相同光源的入射光并同轴地入射到偏振分束器来产生参考信号光和信号光。