公开(公告)号：US20100076224A1

公开(公告)日：2010-03-25

申请号：US12159459

申请日：2006-12-27

申请人： Tomoyoshi Nozaki ,  Takeshi Toru ,  Norio Shibata ,  Masaichi Yamamoto

发明人： Tomoyoshi Nozaki ,  Takeshi Toru ,  Norio Shibata ,  Masaichi Yamamoto

IPC分类号： C07C237/06

CPC分类号： C07C323/60 ,  C07C2602/08

摘要： A compound represented by the formula (I) is used as an active ingredient in a medicament for treatment or prevention of infectious diseases caused by protozoa or bacterium. X represents halogen, Z represents —(CH2)m— wherein m is an integer of 1-5, and R represents one of the following (i)-(v): (i) hydrogen n represents an integer of 0-5, R1's independently represent hydrogen, halogen, alkoxy having 1-5 carbon atoms or alkyl having 1-5 carbon atoms. R2's independently represent hydrogen, halogen, alkoxy having 1-5 carbon atoms or alkyl having 1-5 carbon atoms. (iv) alkyl having 1-5 carbon atoms, (v) hydroxyalkyl having 1-5 carbon atoms.

摘要翻译： 在由用于治疗或预防由原生动物或细菌引起的感染性疾病的药物中使用由式（I）表示的化合物作为活性成分。 X表示卤素，Z表示 - （CH 2）m - ，其中m为1-5的整数，R表示以下（i） - （v）中的一个：（i）氢n表示0-5的整数， R 1独立地表示氢，卤素，具有1-5个碳原子的烷氧基或具有1-5个碳原子的烷基。 R 2独立地表示氢，卤素，具有1-5个碳原子的烷氧基或具有1-5个碳原子的烷基。 （iv）具有1-5个碳原子的烷基，（v）具有1-5个碳原子的羟烷基。

公开(公告)号：US07638654B2

公开(公告)日：2009-12-29

申请号：US12224664

申请日：2007-03-02

申请人： Takeshi Toru ,  Norio Shibata ,  Shuichi Nakamura ,  Takeo Fukuzumi

发明人： Takeshi Toru ,  Norio Shibata ,  Shuichi Nakamura ,  Takeo Fukuzumi

IPC分类号： C07C315/04 ,  C07C317/14

CPC分类号： C07C317/14

摘要： A novel 1-fluoro-1,1-bis(arylsulfonyl)methane is provided which is useful in monofluoromethylation. Also provided is a production method thereof.A method for producing a fluorobis(arylsulfonyl)methane, the method including the steps of: treating a bis(arylsulfonyl)methane represented by the following formula (1), (ArSO2)2CH2  (1) (wherein Ar represents a substituted or unsubstituted phenyl group or naphthyl group) with a base; and then adding a fluorination reagent thereto, to produce fluorobis(arylsulfonyl)methane represented by the following formula (2) (ArSO2)2CHF  (2) (wherein Ar is defined as above), and a fluorobis(arylsulfonyl)methane (2) represented by the above formula (2), which is a novel compound that is very useful in producing a monofluoromethyl.

摘要翻译： 提供了一种新颖的1-氟-1,1-双（芳基磺酰基）甲烷，其可用于单氟甲基化。 还提供了其制备方法。 一种制备氟双（芳基磺酰基）甲烷的方法，所述方法包括以下步骤：处理由下式（1）表示的双（芳基磺酰基）甲烷，（ArSO 2）2 CH 2（1）（其中Ar表示取代或未取代的苯基 基团或萘基）; 然后向其中加入氟化试剂，得到由下式（2）（ArSO 2）2 CHF（2）（其中Ar如上定义）表示的氟双（芳基磺酰基）甲烷和表示为氟代双（芳基磺酰基）甲烷（2） 通过上述式（2），其是在制备单氟甲基中非常有用的新型化合物。

公开(公告)号：US07112348B2

公开(公告)日：2006-09-26

申请号：US10732273

申请日：2003-12-11

申请人： Toshihiro Mandai ,  Mikio Tomaru ,  Norio Shibata

发明人： Toshihiro Mandai ,  Mikio Tomaru ,  Norio Shibata

IPC分类号： B05D5/00 ,  B05D3/12 ,  B05C11/10

CPC分类号： B05C11/1039 ,  B05C5/0254 ,  B05C5/0258 ,  B05D1/26 ,  G03C1/74 ,  G11B5/842

摘要： The coating apparatus and method enable the coating liquid having been scraped-off to be reused without doing any one of the fluid adjusting treatment and the filtering treatment, while maintaining the features of the scraping-off type of extrusion coater, which is suitable for obtaining a uniform and extremely thin coating film. The coating head is provided with two slits: a coating slit and a recovering slit, and the excessive coating liquid having been discharged through the coating slit and applied to the web is scraped-off and recovered through the recovering slit.

公开(公告)号：US06818062B2

公开(公告)日：2004-11-16

申请号：US10281970

申请日：2002-10-29

申请人： Mikio Tomaru ,  Toshihiro Mandai ,  Norio Shibata

发明人： Mikio Tomaru ,  Toshihiro Mandai ,  Norio Shibata

IPC分类号： B05C1104

CPC分类号： G03C1/74 ,  B05C5/0254 ,  B05C5/0262 ,  B05C11/02 ,  B05C11/025 ,  B05C11/04 ,  B05C11/041 ,  B05C11/045 ,  B05D1/265 ,  B05D1/42 ,  G03C2001/7459 ,  G11B5/848

摘要： It is possible to give ultrathin and uniform coating on a flexible web in scraping-off type coating. The distribution of pressure in a web width direction is adjusted by a pressure distribution adjusting device when an excess of coating liquid excessively applied is scraped off by a doctor blade by giving relative pressure to a coating surface of a web and the doctor blade after applying the coating liquid that is more excessive than the desired quantity of the coating liquid on the web by a precoating apparatus while making the web continuously travel.

摘要翻译： 可以在刮擦式涂层的柔性网上给出超薄均匀的涂层。 当通过施加过量的涂布液被刮刀刮除过量的涂布液时，通过压力分布调节装置调节幅材宽度方向上的压力分布，施加相对于幅材的涂布表面和刮刀的相对压力 在使幅材连续行进的同时，通过预涂装置将超过所需量的涂布液涂布在纸幅上。

公开(公告)号：US06410094B1

公开(公告)日：2002-06-25

申请号：US09251400

申请日：1999-02-17

申请人： Toshihiro Mandai ,  Norio Shibata

发明人： Toshihiro Mandai ,  Norio Shibata

IPC分类号： B05D312

摘要： An extrusion coating head comprises an upstream side block (12) and a downstream side block (13) aligned in the conveying direction, and adjusting mechanism. The upstream and downstream side blocks (12, 13) respectively have edge surfaces (12a, 13a) on which the flexible support (1) is pressed. The upstream and downstream side blocks (12, 13) define therebetween a slit (15b) through which a coating composition can be extruded and applied onto the flexible support. The adjusting mechanism adjusts a length (t) of a perpendicular line which is drawn from an upstream end (A) of the edge surface of the downstream side block to a tangential line (L) of the edge surface of the downstream side block which is drawn from a downstream end of the edge surface of the upstream side block, to thereby adjust a distribution of a coating thickness on the flexible support in the width direction.

公开(公告)号：US6153265A

公开(公告)日：2000-11-28

申请号：US325476

申请日：1994-10-19

申请人： Mikio Tomaru ,  Norio Shibata ,  Shinsuke Takahashi ,  Akihiro Suzuki

发明人： Mikio Tomaru ,  Norio Shibata ,  Shinsuke Takahashi ,  Akihiro Suzuki

IPC分类号： B05C5/02 ,  B05C9/06 ,  G03C1/74 ,  G11B5/842 ,  B05D3/12 ,  B05C3/12

CPC分类号： B05C9/06 ,  B05C11/023 ,  B05C5/0254 ,  B05C5/0266 ,  G03C1/74 ,  B05C1/0826 ,  B05C9/10

摘要： Coating equipment 20 with an extrusion type coating head comprising a back edge 6 having a top side which slopes away from a support from the height of the top of a front edge 5, a coating fluid spouting slot 4 defined by both the edges, and guide plates for regulating the width of a coating fluid spouted from the slot tip on both side ends of the slot for applying the coating fluid to the support surface from the slot 4 in a non-pressurized condition. The nearest point to the support surface in the slot corresponding portion of the upper edge of the guide plate 7 is positioned slightly upstream from the center line of the width of the slot along the support running direction and the area given by the product of the distance between the nearest point and the support surface and the width of the slot is made a specific value or less. The coating equipment thus formed has no risk of damaging the support and effectively lessens the effect of air entering from both end sides of an application point of a coating fluid during a high speed thin coat application and produces no film cut when the coating fluid is applied to the running support surface by non-pressurization type coating equipment.

摘要翻译： 具有挤出型涂覆头的涂覆设备20包括后边缘6，后边缘6具有从前边缘5的顶部的高度离开支撑件的顶侧，由两个边缘限定的涂布流体喷射槽4和引导件 用于调节从狭缝尖端在槽的两个侧端处喷出的涂布液的宽度的板，用于在非加压状态下将涂布流体从槽4施加到支撑表面。 在引导板7的上边缘的槽对应部分中与支撑表面的最近点位于沿着支撑行进方向的槽的宽度的中心线的稍微上游，并且由距离 在最近点和支撑表面之间，并且槽的宽度被设定为特定值或更小。 如此形成的涂布设备不会损坏支撑体并且有效地降低在高速薄涂层施加期间从涂布液的涂布点的两个端部进入的空气的影响，并且当施加涂布液时不产生膜切割 通过非加压型涂布设备到运行的支撑表面。

公开(公告)号：US5633050A

公开(公告)日：1997-05-27

申请号：US500556

申请日：1995-07-11

申请人： Norio Shibata ,  Shinsuke Takahashi

发明人： Norio Shibata ,  Shinsuke Takahashi

IPC分类号： G11B5/70 ,  G11B5/738 ,  G11B5/845 ,  G11B5/852 ,  H01F1/00

CPC分类号： G11B5/852 ,  G11B5/70 ,  G11B5/738 ,  G11B5/845

摘要： A method for producing a magnetic recording medium which results in the effective oblique orientation of magnetic fine particles without aggregation of the particles. The method results in a magnetic recording medium having an upper magnetic layer containing needle-shaped, granular, or plate-like magnetic particles, and at least one lower nonmagnetic layer formed on a nonmagnetic support so that the magnetic particles have the maximum degree of orientation in an oblique or perpendicular direction with respect to a surface of the support. The oblique or perpendicular orientation is performed in the wet state of a magnetic layer and in the condition in which the amount of the solvent residue in the upper magnetic layer is 40 to 80% after the upper magnetic layer and the lower nonmagnetic layer are applied sequentially or simultaneously to form a multilayer. The upper magnetic layer is formed so as to be thinner than the lower nonmagnetic layer and subjected to horizontal orientation with a plane of the surface of the support.

摘要翻译： 一种制造磁记录介质的方法，其导致磁性细颗粒的有效倾斜取向而不会聚集颗粒。 该方法产生具有包含针状，粒状或板状磁性颗粒的上磁性层的磁记录介质和形成在非磁性载体上的至少一个下非磁性层，使得磁性颗粒具有最大取向度 在相对于支撑体的表面的倾斜或垂直方向上。 倾斜或垂直取向在磁性层的湿润状态下进行，并且在上部磁性层和下部非磁性层依次施加之后上部磁性层中的溶剂残留量为40〜80％的条件下进行 或同时形成多层。 上磁性层形成为比下部非磁性层薄，并且与支撑体的表面的平面进行水平取向。

公开(公告)号：US5518773A

公开(公告)日：1996-05-21

申请号：US348070

申请日：1994-11-23

申请人： Norio Shibata ,  Akihiro Suzuki ,  Shinsuke Takahashi ,  Mikio Tomaru

发明人： Norio Shibata ,  Akihiro Suzuki ,  Shinsuke Takahashi ,  Mikio Tomaru

IPC分类号： B05C5/02 ,  B05C9/06 ,  G03C1/74 ,  G11B5/848 ,  B05D1/26

CPC分类号： G11B5/848 ,  B05C5/0254 ,  B05C9/06 ,  G03C1/74

摘要： A coating apparatus for forming one or more coating layers on a substrate by means of an extrusion-type head comprising a front edge located on an upstream side with respect to a moving direction of the substrate and a back edge which is located on a downstream side in the moving direction of the substrate. The back edge has a corner portion partially defining an extrusion slot and which is displaced further from the substrate than the front edge in a state in which a precoating solution comprised mainly of an organic solvent is applied in advance on a coating surface of the substrate. A chamfered surface is formed on the corner portion. According to the invention, an angle .alpha. formed by the chamfered surface and a downstream inclined surface of the back edge is such that 40.degree..ltoreq..alpha..ltoreq.140.degree., an angle .beta. formed by chamfered surface and an upstream inclined surface of the back edge is such that 40.degree..ltoreq..beta.

摘要翻译： 一种涂布装置，用于通过挤出型头在衬底上形成一个或多个涂层，所述挤出型头包括相对于衬底的移动方向位于上游侧的前边缘和位于下游侧的后边缘 在基板的移动方向上。 后边缘具有部分地限定挤出槽的角部，并且预先在基材的涂布表面上预先涂布主要由有机溶剂组成的预涂溶液的状态，其比前边缘更远离基板的位置。 在角部形成倒角面。 根据本发明，由倒角表面和后边缘的下游倾斜表面形成的角度α为40°，角度β由倒角表面形成，上游倾斜表面为 后边缘使得倒角表面的40°<180°，宽度L（mm）为0.002×L。 此外，由后边缘的下游倾斜表面和从头部逐渐延伸的基板形成的角度θ被设定为不小于25°。

公开(公告)号：US5424100A

公开(公告)日：1995-06-13

申请号：US186822

申请日：1994-01-26

申请人： Shinsuke Takahashi ,  Norio Shibata

发明人： Shinsuke Takahashi ,  Norio Shibata

IPC分类号： B05C5/02 ,  B05C9/06 ,  B05D1/26 ,  B05D1/36 ,  G11B5/842 ,  G11B5/848

CPC分类号： G11B5/848 ,  B05C5/0254 ,  B05C9/06

摘要： A coating method and a coating apparatus are constructed for simultaneously coating a plurality of different organic-solvent-based coating liquids each composed of a non-newtonian fluid having fine particles dispersed therein to form a multi-layered structure having three or more layers on a strip of continuously travelling non-magnetic supporting substrate with the aid of an extrusion type coating head. The coating liquids are instantaneously injected through the corresponding slits. The coating liquid for the lowermost layer is a non-magnetic liquid. The coated layers are successively formed one above another with the aid of a doctor edge plane located on the downstream side of each slit. The coating head is constructed such that each doctor edge plane does not pass a tangential line extending from the upstream end of an opening portion of each slit to a doctor edge of a slit located on the downstream side and that a coating liquid injected through a slit on the upstream side merges with a coating liquid injected through a slit on the downstream side while defining a predetermined merging angle therebetween.

摘要翻译： 构造涂布方法和涂布装置，以同时涂布多种不同的有机溶剂型涂布液，每种不同的有机溶剂型涂布液由分散有细颗粒的非牛顿流体组成，形成具有三层或更多层的多层结构 借助于挤出型涂布头，连续行进的非磁性支撑基材的条带。 涂层液体通过相应的狭缝瞬时注入。 用于最下层的涂布液是非磁性液体。 借助于位于每个狭缝的下游侧的刮刀边缘平面，将涂层依次形成在另一个上。 涂布头被构造成使得每个刮刀边缘平面不通过从每个狭缝的开口部分的上游端延伸到位于下游侧的狭缝的刮刀边缘的切线，并且通过狭缝喷射的涂布液 在上游侧与通过下游侧的狭缝喷射的涂布液合并，同时在其间限定预定的合并角度。

公开(公告)号：US5389147A

公开(公告)日：1995-02-14

申请号：US935158

申请日：1992-08-26

申请人： Keiji Shigesada ,  Akihiro Suzuki ,  Norio Shibata

发明人： Keiji Shigesada ,  Akihiro Suzuki ,  Norio Shibata

IPC分类号： B05C1/02 ,  B05C5/02 ,  B08B1/00 ,  G11B5/842 ,  B05C11/08

CPC分类号： G11B5/842

摘要： An apparatus for automatically cleaning surfaces of an application apparatus is disclosed. The invention is characterized in that it includes a basement extending in parallel with the longitudinal direction of an application apparatus used to apply a magnetic dispersion liquid to a flexible carrier, a tracer movable on the basement, a traverser which can be moved from the tracer to a position over the edge surfaces of the application apparatus and be moved vertically relative to the surfaces, and a cleaning head coupled to the traverser at the end portion thereof so that the head can be placed in elastic contact with the edge surfaces.

摘要翻译： 公开了一种用于自动清洁应用设备表面的设备。 本发明的特征在于，它包括一个与应用装置的纵向方向平行延伸的基底，用于将磁性分散液施加到柔性载体上，可在基底上移动的示踪器，可从示踪器移动的横越器 位于施加装置的边缘表面上并相对于表面垂直移动的位置，以及清洁头，其端部处连接到横动器，使得头可以与边缘表面弹性接触。