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公开(公告)号:US20160214959A1
公开(公告)日:2016-07-28
申请号:US15088786
申请日:2016-04-01
IPC分类号: C07D401/06 , C07D401/14 , C07D409/06 , C07D413/14 , C07D405/14 , C07F9/6558 , C07D417/14 , C07D409/14 , C07D403/06
CPC分类号: C07D401/06 , A01N43/713 , A01N43/84 , A01N57/16 , A61K31/4439 , C07D401/14 , C07D403/06 , C07D403/14 , C07D405/14 , C07D409/06 , C07D409/14 , C07D413/14 , C07D417/14 , C07F9/06 , C07F9/65583 , Y02A50/409 , Y02A50/411 , Y02A50/414 , Y02A50/415
摘要: The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
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公开(公告)号:US20150099750A1
公开(公告)日:2015-04-09
申请号:US14557117
申请日:2014-12-01
发明人: William J. Hoekstra , Stephen W. Rafferty , Christopher M. Yates , Robert J. Schotzinger , Michael R. Loso , Michael T. Sullenberger
IPC分类号: C07D401/06 , C07D417/06 , C07D413/06 , C07D401/14 , C07D409/14
CPC分类号: C07D401/06 , A01N43/54 , A01N43/56 , A01N43/647 , A01N43/653 , A01N43/713 , A01N43/76 , A01N43/78 , A01N43/84 , C07D401/14 , C07D405/06 , C07D409/14 , C07D413/06 , C07D417/06
摘要: The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
摘要翻译: 本发明描述了具有金属酶调节活性的化合物,以及治疗由这些金属酶介导的疾病,病症或症状的方法。
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公开(公告)号:US08623892B2
公开(公告)日:2014-01-07
申请号:US13784466
申请日:2013-03-04
IPC分类号: C07D413/10 , C07D401/06 , C07D249/04
CPC分类号: A61K31/4725 , A01N43/647 , A61K31/4192 , A61K31/422 , A61K31/4709 , A61K45/06 , C07D249/04 , C07D401/06 , C07D405/12 , C07D409/14 , C07D413/10 , C07D413/12 , A61K2300/00
摘要: The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
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公开(公告)号:US10017494B2
公开(公告)日:2018-07-10
申请号:US15126420
申请日:2015-03-19
申请人: Viamet Pharmaceuticals, Inc. , The United States of America, as represented by the Department of Health and Human Services
发明人: William J. Hoekstra , Christopher M. Yates , Mark Behnke , Asaf Alimardanov , Scott A. David , Douglas Franklin Fry
IPC分类号: C07D405/06 , C07D213/50 , C07D213/30 , C07D401/06 , C07D213/38 , C07D213/56
摘要: The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof.
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公开(公告)号:US09938255B2
公开(公告)日:2018-04-10
申请号:US15088786
申请日:2016-04-01
IPC分类号: A01N57/00 , A61K31/675 , C07D401/06 , A61K31/4439 , C07D409/14 , C07D401/14 , C07D405/14 , C07D413/14 , C07D403/06 , C07D403/14 , C07D409/06 , C07D417/14 , A01N43/713 , A01N43/84 , A01N57/16 , C07F9/06 , C07F9/6558
CPC分类号: C07D401/06 , A01N43/713 , A01N43/84 , A01N57/16 , A61K31/4439 , C07D401/14 , C07D403/06 , C07D403/14 , C07D405/14 , C07D409/06 , C07D409/14 , C07D413/14 , C07D417/14 , C07F9/06 , C07F9/65583 , Y02A50/409 , Y02A50/411 , Y02A50/414 , Y02A50/415
摘要: The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
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公开(公告)号:US20170121307A1
公开(公告)日:2017-05-04
申请号:US15317006
申请日:2016-03-17
IPC分类号: C07D401/06
CPC分类号: C07D401/06
摘要: The present invention relates to polymorphic forms of compound 1 or 1a and processes for preparing compound 1 and 1a polymorphs, which are useful as antifungal agents. In particular, the invention seeks to provide a new methodology for preparing polymorphs of compound 1 and substituted derivatives thereof.
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公开(公告)号:US09414596B2
公开(公告)日:2016-08-16
申请号:US14373304
申请日:2013-01-18
IPC分类号: A01N43/713 , A01N43/56 , A01N43/653 , A01N43/647 , A01N57/16
CPC分类号: A01N43/713 , A01N43/56 , A01N43/647 , A01N43/653 , A01N57/16
摘要: The present disclosure describes compounds having agricultural fungicidal activity.
摘要翻译: 本公开内容描述了具有农业杀真菌活性的化合物。
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公开(公告)号:US20160130263A1
公开(公告)日:2016-05-12
申请号:US14897331
申请日:2014-06-11
IPC分类号: C07D413/14 , A61K31/4439 , A61K45/06 , C07D401/14 , A61K31/496 , C07D401/06 , C07D409/14
CPC分类号: C07D413/14 , A01N43/713 , A01N43/84 , A01N43/86 , A61K31/4439 , A61K31/496 , A61K45/06 , C07D401/06 , C07D401/14 , C07D409/14 , Y02A50/409 , Y02A50/411 , Y02A50/414
摘要: The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
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公开(公告)号:US09221791B2
公开(公告)日:2015-12-29
申请号:US14457620
申请日:2014-08-12
发明人: William J. Hoekstra , Stephen W. Rafferty , Christopher M. Yates , Robert J. Schotzinger , Michael R. Loso , Michael T. Sullenberger , Gary D. Gustafson
IPC分类号: A01N43/54 , C07D401/06 , C07D401/14 , A01N43/56 , A01N43/647 , A01N43/713 , A01N43/76 , A01N43/78 , C07D405/06 , C07D409/14 , C07D413/06 , C07D417/06 , A01N43/653 , A01N43/84
CPC分类号: C07D401/06 , A01N43/54 , A01N43/56 , A01N43/647 , A01N43/653 , A01N43/713 , A01N43/76 , A01N43/78 , A01N43/84 , C07D401/14 , C07D405/06 , C07D409/14 , C07D413/06 , C07D417/06
摘要: The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
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公开(公告)号:US20140288107A1
公开(公告)日:2014-09-25
申请号:US14297065
申请日:2014-06-05
发明人: William J. Hoekstra , Christopher M. Yates , Robert J. Schotzinger , Michael R. Loso , Zachary A. Buchan , Michael T. Sullenberger , Gary D. Gustafson
IPC分类号: A01N43/713
CPC分类号: A01N43/713 , A01N25/00 , A01N43/647 , A01N43/653 , A01N43/78 , C07D401/06 , C07D401/14 , C07D409/14 , C07D417/14
摘要: The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
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