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公开(公告)号：US10000465B2
公开(公告)日：2018-06-19
申请号：US15126412
申请日：2015-03-19
申请人： Viamet Pharmaceuticals, Inc. , The United States of America, as represented by the Department of Health and Human Services
发明人： William J. Hoekstra , Christopher M. Yates , Mark Behnke , Asaf Alimardanov , Scott A. David , Douglas Franklin Fry
IPC分类号： C07D213/26 , C07D401/06 , C07B57/00 , C07D213/57 , C07F7/18
CPC分类号： C07D401/06 , A61K31/4439 , C07B57/00 , C07B2200/07 , C07D213/57 , C07F7/1804
摘要： The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof.
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公开(公告)号：US09981943B2
公开(公告)日：2018-05-29
申请号：US15126363
申请日：2015-03-19
申请人： Viamet Pharmaceuticals, Inc. , The United States of America, as represented by the Department of Health and Human Services
发明人： William J. Hoekstra , Christopher M. Yates , Mark Behnke , Asaf Alimardanov , Scott A. David , Douglas Franklin Fry
IPC分类号： C07D401/06 , C07D213/38
CPC分类号： C07D401/06 , C07D213/38 , C07D213/84
摘要： The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof.
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公开(公告)号：US10017494B2
公开(公告)日：2018-07-10
申请号：US15126420
申请日：2015-03-19
申请人： Viamet Pharmaceuticals, Inc. , The United States of America, as represented by the Department of Health and Human Services
发明人： William J. Hoekstra , Christopher M. Yates , Mark Behnke , Asaf Alimardanov , Scott A. David , Douglas Franklin Fry
IPC分类号： C07D405/06 , C07D213/50 , C07D213/30 , C07D401/06 , C07D213/38 , C07D213/56
摘要： The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof.
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公开(公告)号：US09220265B2
公开(公告)日：2015-12-29
申请号：US14297065
申请日：2014-06-05
发明人： William J. Hoekstra , Christopher M. Yates , Robert J. Schotzinger , Michael R. Loso , Zachary A. Buchan , Michael T. Sullenberger , Gary D. Gustafson
IPC分类号： A01N43/78 , A01N43/713 , C07D401/14 , C07D401/06 , C07D409/14 , C07D417/14 , A01N25/00 , A01N43/647 , A01N43/653
CPC分类号： A01N43/713 , A01N25/00 , A01N43/647 , A01N43/653 , A01N43/78 , C07D401/06 , C07D401/14 , C07D409/14 , C07D417/14
摘要： The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
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公开(公告)号：US20140350003A1
公开(公告)日：2014-11-27
申请号：US14457620
申请日：2014-08-12
发明人： William J. Hoekstra , Stephen W. Rafferty , Christopher M. Yates , Robert J. Schotzinger , Michael R. Loso , Michael T. Sullenberger , Gary D. Gustafson
IPC分类号： A01N43/713 , A01N43/84 , A01N43/76 , A01N43/78 , A01N43/54 , A01N43/647 , A01N43/56 , A01N43/653
CPC分类号： C07D401/06 , A01N43/54 , A01N43/56 , A01N43/647 , A01N43/653 , A01N43/713 , A01N43/76 , A01N43/78 , A01N43/84 , C07D401/14 , C07D405/06 , C07D409/14 , C07D413/06 , C07D417/06
摘要： The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
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公开(公告)号：US09802914B2
公开(公告)日：2017-10-31
申请号：US15126330
申请日：2015-03-19
IPC分类号： C07D401/06 , C07D213/26 , C07D213/61 , A61K31/4439 , A61K45/06 , C07D213/30 , C07D213/50
CPC分类号： C07D401/06 , A61K31/4439 , A61K45/06 , C07D213/26 , C07D213/30 , C07D213/50 , C07D213/61
摘要： The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 or 1a and substituted derivatives thereof.
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公开(公告)号：US20170081285A1
公开(公告)日：2017-03-23
申请号：US15126392
申请日：2015-03-19
申请人： Viamet Pharmaceuticals, Inc. , The US, as reprsented by the Department of Health and Human Services
发明人： William J. Hoekstra , Christopher M. Yates , Mark Behnke , Asaf Alimardanov , Scott A. David , Douglas Franklin Fry
IPC分类号： C07D213/50 , C07D401/06
CPC分类号： C07D213/50 , C07D213/30 , C07D213/38 , C07D401/06 , C07D405/06
摘要： The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof.
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公开(公告)号：US20160214959A1
公开(公告)日：2016-07-28
申请号：US15088786
申请日：2016-04-01
IPC分类号： C07D401/06 , C07D401/14 , C07D409/06 , C07D413/14 , C07D405/14 , C07F9/6558 , C07D417/14 , C07D409/14 , C07D403/06
CPC分类号： C07D401/06 , A01N43/713 , A01N43/84 , A01N57/16 , A61K31/4439 , C07D401/14 , C07D403/06 , C07D403/14 , C07D405/14 , C07D409/06 , C07D409/14 , C07D413/14 , C07D417/14 , C07F9/06 , C07F9/65583 , Y02A50/409 , Y02A50/411 , Y02A50/414 , Y02A50/415
摘要： The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
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公开(公告)号：US20150099750A1
公开(公告)日：2015-04-09
申请号：US14557117
申请日：2014-12-01
发明人： William J. Hoekstra , Stephen W. Rafferty , Christopher M. Yates , Robert J. Schotzinger , Michael R. Loso , Michael T. Sullenberger
IPC分类号： C07D401/06 , C07D417/06 , C07D413/06 , C07D401/14 , C07D409/14
CPC分类号： C07D401/06 , A01N43/54 , A01N43/56 , A01N43/647 , A01N43/653 , A01N43/713 , A01N43/76 , A01N43/78 , A01N43/84 , C07D401/14 , C07D405/06 , C07D409/14 , C07D413/06 , C07D417/06
摘要： The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
摘要翻译： 本发明描述了具有金属酶调节活性的化合物，以及治疗由这些金属酶介导的疾病，病症或症状的方法。
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公开(公告)号：US20170144991A1
公开(公告)日：2017-05-25
申请号：US15126363
申请日：2015-03-19
申请人： Viamet Pharmaceuticals, Inc. , The US, as represented by the Department of Health and Human Services
发明人： William J. Hoekstra , Christopher M. Yates , Mark Behnke , Asaf Alimardanov , Scott A. David , Douglas Franklin Fry
IPC分类号： C07D401/06 , C07D213/38
CPC分类号： C07D401/06 , C07D213/38 , C07D213/84
摘要： The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof.
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