公开(公告)号：US06245535B1

公开(公告)日：2001-06-12

申请号：US09463912

申请日：2000-02-02

申请人： Yutaka Takano ,  Masaru Hasegawa ,  Hideo Mori ,  Katsuhiko Ando ,  Keiko Ochiai ,  Hiroaki Motoyama ,  Akio Ozaki

发明人： Yutaka Takano ,  Masaru Hasegawa ,  Hideo Mori ,  Katsuhiko Ando ,  Keiko Ochiai ,  Hiroaki Motoyama ,  Akio Ozaki

IPC分类号： C12P762

CPC分类号： C12R1/07 ,  C12P7/62 ,  C12P17/06

摘要： Disclosed is a process for producing a compound represented by general formula (II-a): (wherein R1 represents a hydrogen atom, a substituted or unsubstituted alkyl group, or an alkali metal; and R2 represents a substituted or unsubstituted alkyl or aryl group) [hereinafter referred to as Compound (II-a)] or the lactone form of Compound (II-a) [hereinafter referred to as Compound (II-b)] which comprises subjecting a compound represented by general formula (I-a): (wherein R1 represents a hydrogen atom, a substituted or unsubstituted alkyl group, or an alkali metal; and R2 represents a substituted or unsubstituted alkyl or aryl group) [hereinafter referred to as Compound (I-a)] or the lactone form of Compound (I-a) [hereinafter referred to as Compound (I-b)] to the action of an enzyme source derived from a microorganism belonging to the genus Bacillus and capable of converting Compound (I-a) or Compound (I-b) into Compound (II-a) or Compound (II-b) in a reaction mixture to form Compound (II-a) or Compound (II-b) in the reaction mixture, and recovering Compound (II-a) or Compound (II-b) from the reaction mixture.

摘要翻译： 公开了一种制备由通式（II-a）表示的化合物的方法：其中R 1表示氢原子，取代或未取代的烷基或碱金属; R 2表示取代或未取代的烷基或芳基） [化学式（II-a）]或化合物（II-a）的内酯形式[以下称为化合物（II-b）]] [其中包括使通式（Ia）表示的化合物 R1表示氢原子，取代或未取代的烷基或碱金属; R2表示取代或未取代的烷基或芳基）[以下称为化合物（Ia）]或化合物（Ia）的内酯形式[ （Ia）或化合物（Ib）转化为化合物（II-a）或化合物（II-a）的酶源的作用，以下称为化合物（Ib） b）在反应混合物中形成化合物（II -a）或化合物（II-b），并从反应混合物中回收化合物（II-a）或化合物（II-b）。

公开(公告)号：US5439822A

公开(公告)日：1995-08-08

申请号：US938333

申请日：1992-08-28

申请人： Ryoichi Katsumata ,  Yutaka Takano

发明人： Ryoichi Katsumata ,  Yutaka Takano

IPC分类号： C12N1/21 ,  C12N9/10 ,  C12N9/38 ,  C12N9/88 ,  C12N15/09 ,  C12N15/60 ,  C12N15/77 ,  C12P21/02 ,  C12R1/01 ,  C12R1/13 ,  C12R1/15 ,  C12N15/11

CPC分类号： C12N9/1033 ,  C12N15/77 ,  C12N9/88 ,  C12Y401/03001

摘要： The present invention provides a gene expression regulatory DNA and a process for preparing a protein using the same.A DNA derived from the isocitrate lyase (ICL) gene of a coryneform bacterium regulates expression of a structural gene encoding a protein when incorporated into a vector DNA together with said structural gene and introduced into a host coryneform bacterium, and a useful protein can be efficiently produced using the DNA.

摘要翻译： 本发明提供了一种基因表达调控DNA及其制备方法。 衍生自棒状杆菌型细菌的异柠檬酸裂解酶（ICL）基因的DNA在与所述结构基因一起掺入载体DNA中时调节编码蛋白质的结构基因的表达，并引入宿主棒状细菌，有效的蛋白质可以有效地 使用DNA产生。

公开(公告)号：US5075533A

公开(公告)日：1991-12-24

申请号：US393746

申请日：1989-09-06

申请人： Hisahiro Fukuoka ,  Yutaka Takano ,  Yoichi Kamiyama

发明人： Hisahiro Fukuoka ,  Yutaka Takano ,  Yoichi Kamiyama

IPC分类号： B23K9/02 ,  B23K9/127 ,  B25J9/16 ,  G05B19/425

CPC分类号： B25J9/1679 ,  B23K9/0216 ,  B23K9/1272 ,  G05B19/425 ,  G05B2219/35286 ,  G05B2219/36417 ,  G05B2219/37405 ,  G05B2219/45104 ,  G05B2219/49384

摘要： A welding torch (4) of a welding robot (RO) is supported by arms (2, 3), to be movable under control by a computer (7). When first and second welded numbers (W1, W2) are woven while oscillating a welding torch (4) along a weld line (WL), data on change in an interspace between the first and second welded members (W1, W2) along direction of the weld line (WL) are previously stored in advance to welding. In the welding, the computer 7 performs arithmetic to obtain command values on the basis of the said data to output the same to the welding robot (RO), so that the welding robot (RO) performs weaving in accordance with the command values while varying a weaving amplitude of the welding torch (4) in response to the change in said interspace.