Surface cutting device, in particular for allergy diagnosis

    公开(公告)号:US11571163B2

    公开(公告)日:2023-02-07

    申请号:US16637500

    申请日:2018-08-07

    Applicant: A2M

    Abstract: The present invention relates to a cutting device comprising a manual gripping element (100) and a cutting assembly (200) that is positioned on one end of the gripping element (100) and comprises a punch (210) split into at least two cutting tips (220, 230), at least one of these tips (220, 230) being hinged on the gripping element (100) in order to be movable between a rest and cutting position in which the tips (220, 230) are adjacent and a working and injection position in which the tips (220, 230) are spaced apart, and urging means (250) designed to move each movable tip (220, 230) into the working position when these urging means (250) press against the skin.

    Methods, compositions, and delivery systems for therapeutic skin treatments

    公开(公告)号:US11433006B2

    公开(公告)日:2022-09-06

    申请号:US16800015

    申请日:2020-02-25

    Abstract: Disclosed are skincare formulations, delivery systems and treatment methods containing an oligopeptide and a combination of antioxidants for topical application to the skin before and/or after dermatological procedures that affect the skin's barrier. The systems herein alleviate discomfort and enable rapid healing of irritated and damaged skin, and provide improved treatment outcomes for dermatological procedures. The disclosed topical formulations, delivery systems, and methods thereof provide enhanced penetration of the active ingredients to the skin while maintaining skin moisture and protecting sensitive skin after dermatological procedures for improvement of aesthetic skin properties. Also provided are methods for therapeutic treatment of dermatological conditions by topically applying, using, for example, a pre-moistened bio-cellulose mask, a formulation comprising (% w/w) at least 0.0001% palmitoyl sh-tripeptide-4 amide on an active basis and at least 0.1% Camellia sinensis leaf extract.

    SURGICAL INSTRUMENT WITH FLEXIBLE END EFFECTOR

    公开(公告)号:US20220175412A1

    公开(公告)日:2022-06-09

    申请号:US17457316

    申请日:2021-12-02

    Abstract: A surgical instrument for removing biological tissue during a surgical procedure comprises an elongate shaft and an end effector connected to the elongate shaft, the end effector including an edge configured to remove tissue, wherein curvature of one or both of the elongate shaft and end effector is adjustable to position the edge along a tissue surface when the curvature of the one or both of the elongate shaft and end effector is adjusted. A method of incising target tissue from an anatomic wall comprises inserting a shaft of a surgical instrument into an anatomic chamber of a patient, positioning a tissue-removal device connected to the shaft proximate the target tissue, deflecting an axis of the tissue-removal device relative to a central axis of the shaft, and shaving a surface of the anatomic wall by moving the tissue-removal device in a deflected state along the target tissue.

    Incising implant for the prostatic urethra

    公开(公告)号:US11304724B2

    公开(公告)日:2022-04-19

    申请号:US15109311

    申请日:2014-12-02

    Applicant: MEDI-TATE LTD.

    Inventor: Ido Kilemnik

    Abstract: An incising implant for creating incisions in the prostatic urethra of a subject, the implant including at least two closed-shaped wires, each of the wires having a proximal section, a distal section and two longitudinal sections extending between the proximal section and the distal section, each of the closed-shaped wires being elastic thereby being compressible into a compressed configuration, each of the longitudinal sections of each of the wires being adjoined with another longitudinal section of another one of the wires.

    INTRAOCULAR DEVICE FOR DUAL INCISIONS

    公开(公告)号:US20210393439A1

    公开(公告)日:2021-12-23

    申请号:US17402244

    申请日:2021-08-13

    Inventor: Malik Y. KAHOOK

    Abstract: A microsurgical device and methods of its use can be used for treatment of various conditions including eye diseases, such as glaucoma, using minimally invasive surgical techniques. A dual-blade device can be used for cutting the trabecular meshwork (“TM”) in the eye. The device tip provides entry into the Schlemm's canal via its size (i.e., for example, 0.2-0.3 mm width) and configuration where a ramp elevates the TM away from the outer wall of the Schlemm's canal and guides the TM to first and second lateral elements for creating first and second incisions through the TM. The dimensions and configuration of the blade is such that an entire strip of TM is removed without leaving TM leaflets behind and without causing collateral damage to adjacent tissues.

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