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48 条记录 (耗时 0.013 秒)

    Reagents for measuring lipase activity
    23.
    发明授权
    Reagents for measuring lipase activity 失效
    测定脂肪酶活性的试剂

    公开(公告)号：US4412951A

    公开(公告)日：1983-11-01

    申请号：US316025

    申请日：1981-10-28

    申请人： Yoshio Inagaki ,  Masaki Okazaki ,  Shinsaku Fujita

    发明人： Yoshio Inagaki ,  Masaki Okazaki ,  Shinsaku Fujita

    IPC分类号： G01N33/50 ,  C09B43/20 ,  C12Q1/44 ,  G01N33/92 ,  C07C107/08

    CPC分类号： C09B43/202 ,  C12Q1/44 ,  G01N2333/00

    摘要： A reagent for measuring a lipase activity comprised of a higher fatty acid ester having the general formula ##STR1## wherein R.sup.1 is a straight chain alkyl group; R.sup.2 is hydrogen or a halogen atom; R.sup.3 and R.sup.4 are independently a nitro group, an alkylsulfonyl group, a substituted alkylsulfonyl group or a trifluoromethyl group; G is an --SO.sub.3 M group or a group having at least one --SO.sub.3 M where M represents sodium or potassium, or, when R.sup.4 has a sulfonic acid group, may be a hydrogen atom; and Q is hydrogen, a halogen atom, an alkyl group, an alkoxy-substituted alkyl group, an alkoxy group, an alkoxy-substituted alkoxy group, a sulfonamido group, a sulfamoyl group, a carbonamido group, a carbamoyl group, or an alkylsulfonyl group. The reagent is capable of releasing a dye on enzymatic hydrolysis by the action of lipase. Because of the released dye has a light absorption zone within the longer wavelength region, it is not substantially disturbed by colored matter contained within blood making it possible to obtain excellent operability and reproducibility in the measurement of lipase activity within blood.

    摘要翻译： 一种用于测量脂肪酶活性的试剂，其由通式为“IMAGE”的高级脂肪酸酯组成，其中R1为直链烷基; R2是氢或卤素原子; R3和R4独立地是硝基，烷基磺酰基，取代的烷基磺酰基或三氟甲基; G是-SO 3 M基或具有至少一个-SO 3 M的基团，其中M表示钠或钾，或者当R 4具有磺酸基时，可以是氢原子; 并且Q是氢，卤素原子，烷基，烷氧基取代的烷基，烷氧基，烷氧基取代的烷氧基，亚磺酰氨基，氨磺酰基，碳酰氨基，氨基甲酰基或烷基磺酰基 组。 试剂能够通过脂肪酶的作用在酶水解上释放染料。 由于释放的染料在较长波长区域内具有吸光区域，所以基本上不会受到血液中含有的有色物质的干扰，从而可以获得优异的可操作性和在血液中测定脂肪酶活性的可重复性。

    Azo compounds of sulfanilamide derivatives
    26.
    发明授权
    Azo compounds of sulfanilamide derivatives 失效
    磺胺衍生物的偶氮化合物

    公开(公告)号：US4124580A

    公开(公告)日：1978-11-07

    申请号：US742625

    申请日：1976-11-17

    申请人： Takeo Takayanagi

    发明人： Takeo Takayanagi

    IPC分类号： C09B29/10 ,  C09B33/10 ,  C07C107/08

    摘要： Azo compounds, which have the formula: ##STR1## in which R is hydrogen or --COCHCl.sub.2, ##STR2## and R.sub.2 is hydrogen or has the meaning as R.sub.1, are useful as chemotherapeutical agents for malignant tumors.

    摘要翻译： 具有下式的偶氮化合物：其中R是氢或-COCHCl 2，其中R 2是氢或具有R 1的含义，可用作恶性肿瘤的化学治疗剂。

    4-(Substituted azobenzenesulfonamides as fasciolicides
    27.
    发明授权
    4-(Substituted azobenzenesulfonamides as fasciolicides 失效
    4-（取代的二苯甲苯磺酰胺作为尖晶石

    公开(公告)号：US3923780A

    公开(公告)日：1975-12-02

    申请号：US40869373

    申请日：1973-10-23

    申请人： MERCK & CO INC

    发明人： HARMON ROBERT E ,  MROZIK HELMUT H

    IPC分类号： A23K1/16 ,  C07D213/77 ,  C07D215/48 ,  C07D231/44 ,  C07D249/14 ,  A01N23/00 ,  C07C107/06 ,  C07C107/08

    CPC分类号： C07D213/77 ,  A23K20/111 ,  C07D215/48 ,  C07D231/44 ,  C07D249/14 ,  Y10S514/893

    摘要： Novel substituted azobenzenesulfonamides are useful as agents for the treatment of both mature and immature liver fluke infections. The azobenzenesulfonamide is substituted on the benzene ring with halogen. The azo substituents are aromatic hdyrocarbons such as phenyl or naphthyl, aromatic heterocycles such as pyridine, triazole and quinoline, aliphatic heterocycles such as imidazoline and pyrimidine trione and aliphatic esters which in turn may be substituted with hydroxyl, amino, loweralkyl, carboxy, hydrazino, nitrile, or ureido. Compositions containing these compounds for the treatment of mature and immature liver fluke infections are also disclosed.

    摘要翻译： 新型取代的偶氮苯磺酰胺可用作治疗成熟和未成熟肝吸虫感染的药剂。 偶氮苯磺酰胺在苯环上被卤素取代。 偶氮取代基是芳基羰基，例如苯基或萘基，芳族杂环如吡啶，三唑和喹啉，脂族杂环如咪唑啉和嘧啶三酮，脂族酯，其又可以被羟基，氨基，低级烷基，羧基，肼基， 腈或脲基。 还公开了含有这些化合物用于治疗成熟和未成熟肝吸虫感染的组合物。

    Disazo pigments
    29.
    发明授权
    Disazo pigments 失效
    DISAZO颜料

    公开(公告)号：US3691149A

    公开(公告)日：1972-09-12

    申请号：US3691149D

    申请日：1970-04-09

    申请人： CIBA GEIGY AG

    发明人： MUELLER WILLY ,  RONCO KARL ,  MORY RUDOLF

    IPC分类号： C09B33/153 ,  C09B43/32 ,  C09B43/38 ,  C07C107/08 ,  C09B43/12

    CPC分类号： C09B33/153 ,  C09B43/32 ,  C09B43/38

    摘要： Disazo dyestuffs of the formula

    摘要翻译： 式R1-N = N-R2-CONH-R3-NHOC-R2-N = N-R1的双偶氮染料，其中R1表示芳基，R2表示羟基萘残基，其中偶氮，羟基和-CO基团 或烯基或可烯化的酮亚甲基化合物的残基，R 3表示含有至少一个羧酸酯，羧酸酰胺，磺酸酯，磺酸酰胺或砜基的亚苯基或二亚苯基残基 是有用的颜料，可用于着色塑料和漆在黄色至红色的色调。

    Phenyl-azo-hydroxynaphtholic acid amide pigments
    30.
    发明授权
    Phenyl-azo-hydroxynaphtholic acid amide pigments 失效
    苯基 - 氨基 - 羟基苯甲酸酰胺颜料

    公开(公告)号：US3652533A

    公开(公告)日：1972-03-28

    申请号：US3652533D

    申请日：1968-11-19

    申请人： CIBA LTD

    发明人： ROUECHE ARMAND

    IPC分类号： C09B29/20 ,  C09B43/32 ,  C07C107/08 ,  C09B29/28

    CPC分类号： C09B43/32 ,  C09B29/20

    摘要： 4-(R7-CO-NH-),5-Y1-PHENYL)-NH-CO-),6-X-NAPHTHALENE


    IN WHICH X IS HYDROGEN, BROMINE, NITRO OR LOWER ALKOXY, Y IS -CO- OR -SO2-, X1 AND X2 EACH IS HYDROGEN, CHLORINE, LOWER ALKYL, LOWER ALKOXY, PHENOXY, CHLOROPHENOXY, LOWER ALKYLPHENOXY, NITRO, LOWER CARBALKOXY, CARBOPHENOXY, LOWER ALKANOYLAMINO OR TRIFLUOROMETHYL, X3 IS HYDROGEN, CHLORINE OR -CONHR5 IN WHICH R5 IS HYDROGEN, LOWER ALKYL, PHENYL OR SUBSTITUTED PHENYL, Y1 AND Y2 EACH IS HYFROGEN, CHLORINE OR LOWER ALKYL AND R6 IS HYDROGEN, LOWER ALKYL, PHENYL OR SUBSTITUTED PHENYL, X4 IS CHLORINE, LOWER ALKYL, LOWER ALKOXY, LOWER CARBOPHENOXY, PHENOXY, CHLOROPHENOXY OR LOWER ALKYL PHENOXY, X5 IS HYDROGEN OR CHLORINE, AND R7 IS HYDROGEN, LOWER ALKYL, AMINO, LOWER ALKYLAMINO, UNSUBSTITUTED PHENYL OR PHENYLAMINO, SUBSTITUTED PHENYL OR SUBSTITUTED PHENYLAMINO; SUITABLE FOR THE SPIN-COLORATION OF FILAMENT AND STAPLE-FIBRE VISCOSE, CELLULOSE ETHERS, CELLULOSE ESTER, POLYAMIDES, POLYURETHANES AND POLYESTER.
    1-(((R6-Y-NH-NH-CO-),X4,X5-PHENYL)-N=N-),2-(HO-),3-((2-Y2,

    NH-CO-),5-Y1-PHENYL)-NH-CO-),6-X-NAPHTHALENE AND

    1-((X1,X2,X3-PHENYL)-N=N-),2-(HO-),3-((2-Y2,4-(R6-Y-NH-

    MONOAZO PIGMENT OF THE FORMULAE