摘要:
Disclosed is a method for stabilizing the color of liquid imidazolines which comprises pre-treating a polyamine with an effective amount of a hydride, preferably a borohydride, followed by its reaction with a fatty acid or ester thereof under amide-forming reaction conditions to make an amide intermediate, followed by subjecting said amide intermediate to imidazoline-forming reaction conditions to make said color-stablized imidazoline product.
摘要:
The novel compound, N,N'-methylenebis (hexahydro-2-oxo-1H-azepine-1-carboxamide) which is useful as a blocked isocyanate to introduce the functionality of methylene diisocyanate and which is prepared by the reaction of isocyanic acid and caprolactam followed by reaction with formaldehyde.
摘要:
A cationactive soil-conditioning composition which comprises one or more active ingredients having the formulae ##STR1## wherein R is a C.sub.10-24 linear or branched alkyl, alkenyl or alk-dienyl group; R.sub.1 is hydrogen, R.sub.2 is hydrogen, C.sub.2-18 as a linear or branched alkyl, alkenyl, alk-dienyl or C.sub.2-18 -alpha-keto-group, R.sub.3 is a hydrogen; R.sub.3 ' if present is hydrogen or C.sub.1-8 alkyl; X and X' are formiate, acetate, propionate, hydrophosphate, hydroxyl, halogenide or nitrate; R.sub.4 methylene, ethylene or a polyglycol ether-group; m is a cardinal number from 1-6 and n is an integer from 1-6; R' is C.sub.10-24 linear or branched alkyl, alkenyl or alk-dienyl; R.sub.5, R.sub.6, R.sub.7 if present, is a hydrogen or taken together two substituents therefrom a CH.dbd.CH--CH.dbd.CH-- group; R.sub.8, R.sub.9, if present, hydrogen or methyl; Y.sub.1 is a --CH.dbd. or oxygen; Y.sub.2 is --NH-- or oxygen; X" is halogenide, acetate, nitrate, sebacate, tartarate, propionate, phosphate, hydrogenphosphate, carbonate, hydrogencarbonate or formiate; m' is a cardinal number from 1-6; m' is an integer from 1-6; R.sub.10 and R.sub.11 are independently from each other hydrogen, ethyl, propyl, oxyethyl, oxypropyl, aminoethyl or aminopropyl-groups; R" is C.sub.9-24 linear or branched alkyl or alkenyl; X'" is nitrate, halogenide, formiate acetate, propionate or butyrate.There is also provided a process for improving the crop-bearing characteristics of soil, in which a composition containing the above active ingredient, is added to soil.
摘要:
Quaternary ammonium derivatives of bisimidazoline compounds which are characterized in having a long chain aliphatic substituent in the 2 and 2'' positions of the respective rings and wherein the 1, 1'' linking entity is an alkylene radical or polyalkylene segments internally joined by an amino or amido nitrogen atom(s). These derivatives are highly effective fabric softeners having unique physical properties.
摘要:
Composition and methods for killing microorganisms using antimicrobial epoxy polymers and epoxy polymer curing agents are described. Compositions containing at least one compound of formula I
where R1 is a phenolic group (e.g., simple phenol, creosote, thymol, or carvacrol), and where R2 is a polyamine (e.g., ethylenediamine (EDA), diethylenetriamine (DETA), triethylenetetramine (TETA), tetraethylenepentamine (TEPA), hexamethylenediamine (HDA)); and optionally a carrier; the compositions may additionally contain at least one epoxy resin. Methods for killing microorganisms involving contacting the microorganisms with an effective microorganism killing amount of the above composition.
摘要:
Provided are compounds, pharmaceutical compositions and methods of treatment or prophylaxis of disorders associated with NMDA receptor activity, including neuropathic pain, stroke, traumatic brain injury, epilepsy, and related neurologic events or neurodegeneration. Compounds are of the general Formula I, or a pharmaceutically acceptable salt, ester, prodrug or derivative thereof are provided: wherein: each (L)k-Ar1 is a substituted or unsubstituted, mono or bicyclic aryl or heteroaryl; W is a bond, alkyl, or alkenyl; X is a bond, NR1 or O and each R1 and R2 is independently H, alkyl, alkenyl or aralkyl or R1 and R2 taken together form a 5-8 membered ring; R3−-R6 are selected from certain specific substituents or a carbonyl; Y is a bond, O, S, SO, SO2, CH2, NH, N(alkyl), or NHC(═O); and Z is OH, NR6R7, NR8SO2(alkyl), NR8C(O)NR6R7, NR8C(O)O(alkyl), NR8-dihydrothiazole, or NR8-dihydroimidazole or wherein Z can fuse with Ar2 to form selected heterocycles.
摘要翻译:提供了治疗或预防与NMDA受体活性相关的病症的化合物,药物组合物和方法,包括神经性疼痛,中风,创伤性脑损伤,癫痫以及相关的神经系统事件或神经变性。 化合物为通式I,或其药学上可接受的盐,酯,前药或衍生物:其中:(L)k-Ar1为取代或未取代的单或双环芳基或杂芳基; W是键,烷基或烯基; X是键,NR 1或O,并且每个R 1和R 2独立地是H,烷基,烯基或芳烷基,或者R 1和R 2一起形成5-8元环; R 3 -R 6选自某些具体取代基或羰基; Y是键,O,S,SO,SO 2,CH 2,NH,N(烷基)或NHC(= O); 并且Z是OH,NR 6 R 7,NR 8 SO 2(烷基),NR 8 C(O)NR 6 R 7,NR 8 C(O)O(烷基),NR 8 - 二氢噻唑或NR 8 - 二氢咪唑,或其中Z可与Ar 2融合形成选定的杂环。