公开(公告)号：US2420938A

公开(公告)日：1947-05-20

申请号：US53042044

申请日：1944-04-10

Applicant: UNION OIL CO

Inventor： DOUMANI THOMAS F ,  COE CLARENCE S

IPC: C07C201/16

CPC classification number: C07C201/16 ,  C07C2601/14 ,  C07C205/05 ,  C07C205/02

公开(公告)号：US2401879A

公开(公告)日：1946-06-11

申请号：US36839140

申请日：1940-12-03

Applicant: MCKEE RALPH H

Inventor： MCKEE RALPH H

IPC: C07C201/16

CPC classification number: C07C201/16 ,  C06B21/0091 ,  C07C201/08 ,  C07C205/06

公开(公告)号：US2372623A

公开(公告)日：1945-03-27

申请号：US44951542

申请日：1942-07-02

Applicant: DU PONT

Inventor： DANIEL ZINNER

IPC: C07C201/16 ,  C10G33/04

CPC classification number: C10G33/04 ,  C07C201/16 ,  C07C205/12

公开(公告)号：US2245945A

公开(公告)日：1941-06-17

申请号：US26403439

申请日：1939-03-24

Applicant: SHELL DEV

Inventor： DIJCK WILLEM JOHANNES DOMINICU ,  ALBERT SCHAAFSMA

IPC: C07C37/72 ,  C07C45/80 ,  C07C51/48 ,  C07C201/16

CPC classification number: C07C37/72 ,  C07C41/38 ,  C07C45/80 ,  C07C51/48 ,  C07C201/16 ,  C07C47/565 ,  C07C55/02 ,  C07C55/10 ,  C07C39/08 ,  C07C43/23 ,  C07C205/22

公开(公告)号：US1981311A

公开(公告)日：1934-11-20

申请号：US67734233

申请日：1933-06-23

Applicant: DU PONT

Inventor： DAHLEN MILES A ,  FOOHEY WILLIAM L

IPC: C07C201/08 ,  C07C201/16 ,  C07C205/12

CPC classification number: C07C201/08 ,  C07C201/16 ,  C07C205/12

公开(公告)号：US1657723A

公开(公告)日：1928-01-31

申请号：US15345626

申请日：1926-12-08

Applicant: BRITISH DYESTUFFS CORP LTD

Inventor： HARRY RODD ERNEST ,  WILLIAM EVERATT REGINALD

IPC: C07C201/16 ,  C07C205/06

CPC classification number: C07C201/16 ,  C07C201/08 ,  C07C205/06

公开(公告)号：US12076670B2

公开(公告)日：2024-09-03

申请号：US17781413

申请日：2020-12-09

Applicant: Covestro Deutschland AG ,  Covestro Intellectual Property GmbH & Co. KG

Inventor： Klaus Mertens ,  Sabine Pegel

IPC: B01D3/42 ,  C07C201/16

CPC classification number: B01D3/425 ,  C07C201/16

Abstract: The present invention relates to a method for continuously operating a distillation column, which is designed to separate a mixture S, which contains essentially a substance A and a substance B, which boils significantly higher than substance A. In the method according to the invention, the reflux ratio is changed according to the feed flow and, at the same time, the energy input by means of the heat-transfer medium is changed proactively (so-called feed-forward control) by accounting for the feed flow by means of feed-forward control. At the same time, the bottom temperature is observed and the control structure is changed if the bottom temperature falls too far when the heat-transfer medium is reduced by means of the feed flow.

公开(公告)号：US11077421B2

公开(公告)日：2021-08-03

申请号：US16128293

申请日：2017-03-24

Applicant: TDA Research, Inc.

Inventor： Girish Srinivas ,  Steven Dietz

IPC: B01J20/20 ,  B01J20/28 ,  B01J20/30 ,  C01B32/30 ,  C07C67/34 ,  C07C67/56 ,  C07C201/12 ,  C07C201/16 ,  C07D209/42 ,  B01D15/00

Abstract: The present invention relates to a carbon sorbent the can selectively remove platinum-group metals and other heavy metals such as tin without co-removing organic synthesis products including pharmaceutical intermediates and finished Active Pharmaceutical Ingredients (APIs). The carbon sorbents of the present invention are made from low-cost, high purity starting materials and the resulting carbon sorbents are also very pure. The carbon sorbents possess a combination of certain nitrogen and phosphorous groups combined with mesoporosity (2 to 50 nm diameter pores) that proves the high metal adsorption.

公开(公告)号：US20210130271A1

公开(公告)日：2021-05-06

申请号：US17123365

申请日：2020-12-16

Applicant: NEONC Technologies, Inc.

Inventor： Thomas CHEN ,  Daniel LEVIN ,  Satish PUPPALI

IPC: C07C29/92 ,  A61K31/045 ,  C07C201/16 ,  C07C201/12 ,  C07C67/14 ,  C07C29/88 ,  C07C29/86 ,  A61K31/4188 ,  A61K45/06 ,  A61N5/10 ,  C07C29/78

Abstract: The present invention provides a process for purifying a monoterpene or sesquiterpene having a purity greater than about 98.5% (w/w). The process comprises the steps of derivatizing the monoterpene (or sesquiterpene) to produce a monoterpene (or sesquiterpene) derivative, separating the monoterpene (or sesquiterpene) derivative, and releasing the monoterpene (or sesquiterpene) from the derivative. Also encompassed by the scope of the present invention is a pharmaceutical composition comprising a monoterpene (or sesquiterpene) having a purity greater than about 98.5% (w/w). The purified monoterpene can be used to treat a disease such as cancer. The present monoterpene (or sesquiterpene) may be administered alone, or may be co-administered with radiation or other therapeutic agents, such as chemotherapeutic agents.

公开(公告)号：US10899691B2

公开(公告)日：2021-01-26

申请号：US16575587

申请日：2019-09-19

Applicant: NEONC Technologies, Inc.

Inventor： Thomas Chen ,  Daniel Levin ,  Satish Puppalli

IPC: C07C29/92 ,  C07C67/14 ,  C07C201/12 ,  A61K31/045 ,  C07C29/78 ,  C07C29/88 ,  C07C201/16 ,  A61K31/4188 ,  A61K45/06 ,  A61N5/10 ,  C07C29/86

Abstract: The present invention provides a process for purifying a monoterpene or sesquiterpene having a purity greater than about 98.5% (w/w). The process comprises the steps of derivatizing the monoterpene (or sesquiterpene) to produce a monoterpene (or sesquiterpene) derivative, separating the monoterpene (or sesquiterpene) derivative, and releasing the monoterpene (or sesquiterpene) from the derivative. Also encompassed by the scope of the present invention is a pharmaceutical composition comprising a monoterpene (or sesquiterpene) having a purity greater than about 98.5% (w/w). The purified monoterpene can be used to treat a disease such as cancer. The present monoterpene (or sesquiterpene) may be administered alone, or may be co-administered with radiation or other therapeutic agents, such as chemotherapeutic agents.