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301.发明申请公开(公告)号：US20160354236A1
公开(公告)日：2016-12-08
申请号：US15174690
申请日：2016-06-06
Applicant: ZOLL Circulation Inc.
Inventor： Michael W. Dae , Timothy R. Machold , Wade A. Keller
IPC: A61F7/12
CPC classification number: A61F7/12 , A61F7/123 , A61F2007/126
Abstract: A method for treating acute coronary syndromes (i.e., unstable angina or non-Q-wave MI) or transient ischemic attacks in a human or animal patient by placing a heat exchange apparatus in the patient=s vasculature and using that heat exchange apparatus to cool the patient to a temperature (e.g. 30-36 degrees C.) at which platelet inhibition (i.e., inhibition of platelet activation and/or aggregation and/or adhesion) occurs. Anti-shivering drugs or anesthesia may be administered to patients whose body temperature is cooled below that patient=s shivering threshold (typically approximately 35.5 degrees C.). If it is determined that platelet inhibition is no longer desirable, such as when the patient is about to undergo a surgical or interventional procedure wherein bleeding could be problematic, the hypothermia-induced platelet inhibition may be rapidly reversed by using the intravascular heat exchange apparatus to re-warm the patient=s body to normothermia or near normothermia.
Abstract translation: 一种通过在患者脉管系统中放置热交换装置并使用该热交换装置冷却来治疗人或动物患者的急性冠状动脉综合征（即不稳定心绞痛或非Q波MI）或短暂性脑缺血发作的方法 患者达到出现血小板抑制（即，抑制血小板活化和/或凝集和/或粘附）的温度（例如30-36摄氏度）。 可将抗发抖药物或麻醉剂施用于体温低于该患者发抖阈值（通常约35.5摄氏度）的患者。 如果确定不再需要血小板抑制，例如当患者即将进行其中出血可能有问题的手术或介入手术时，通过使用血管内热交换装置可以快速逆转低体温诱导的血小板抑制 将患者身体重新加热至正常体温或接近正常体温。
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公开(公告)号：US20160354234A1
公开(公告)日：2016-12-08
申请号：US15063299
申请日：2016-03-07
Applicant: ZOLL CIRCULATION, INC.
Inventor： Jeremy Dabrowiak
CPC classification number: A61F7/12 , A61F7/007 , A61F7/0085 , A61F2007/0054 , A61F2007/0056 , A61F2007/0076 , A61F2007/0086 , A61F2007/0095 , A61F2007/0295 , A61F2007/126
Abstract: A system and method for adding or removing heat from a heat exchange fluid circulating between an external heat exchanger and an intravascular heat exchange catheter is described. The system includes a two stage cooling system providing for a high rate of cooling in one stage and a lower rate of cooling in a second stage. Both stages may be used to provide maximal cooling while the second stage is used to provide improved control of the cooling rate as a target temperature is approached. The second stage may also be used to provide heat to the heat exchange fluid.
Abstract translation: 描述了一种用于从在外部热交换器和血管内热交换导管之间循环的热交换流体添加或除去热量的系统和方法。 该系统包括两级冷却系统，其在一个阶段提供高的冷却速率，在第二阶段提供较低的冷却速度。 可以使用两个阶段来提供最大的冷却，而第二阶段用于在接近目标温度时提供改进的冷却速度控制。 第二阶段也可用于向热交换流体提供热量。
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303.发明申请公开(公告)号：US20160254682A1
公开(公告)日：2016-09-01
申请号：US14949649
申请日：2015-11-23
Applicant: Zoll Circulation, Inc.
Inventor： Sean Yip , David Mack
Abstract: An intelligent rechargeable battery pack having a battery management system for monitoring and controlling the charging and discharging of the battery pack is described. The battery management system includes a memory for storing data related to the operation of the battery, and the battery management system is also configured to communicate the data related to the operation of the battery to other processors for analysis.
Abstract translation: 描述了具有用于监测和控制电池组的充电和放电的电池管理系统的智能可充电电池组。 电池管理系统包括用于存储与电池的操作相关的数据的存储器，并且电池管理系统还被配置为将与电池的操作相关的数据传送到其他处理器用于分析。
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公开(公告)号：US09357967B2
公开(公告)日：2016-06-07
申请号：US14445892
申请日：2014-07-29
Applicant: ZOLL Circulation, Inc.
Inventor： Jeffrey P. Callister , Michael W. Dae , Amy L. Hammack
CPC classification number: A61B5/6852 , A61B5/0008 , A61B5/01 , A61B2017/00084 , A61F7/12 , A61F2007/126 , A61M25/0662
Abstract: An introducer sheath/temperature probe assembly that is insertable into a blood vessel of a human or veterinary patent to measure the temperature of blood flowing through that blood vessel. The introducer sheath/temperature probe assembly may be used in conjunction with an indwelling heat exchange catheter system to warm or cool all or a portion of the patient's body to a desired target temperature and to maintain such target temperature for a desired period of time.
Abstract translation: 导引鞘/温度探针组件，其可插入人或兽医专利的血管中，以测量流过该血管的血液的温度。 导引鞘/温度探针组件可以与留置的热交换导管系统一起使用，以将患者身体的全部或一部分加热或冷却到期望的目标温度，并将该目标温度保持在期望的时间段内。
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公开(公告)号：US20160143773A1
公开(公告)日：2016-05-26
申请号：US15009128
申请日：2016-01-28
Applicant: Zoll Circulation, Inc.
Inventor： Richard A. Helkowski , Jeremy T. Dabrowiak , Alex L. Lim , Venkata Vishnu Gurukula
IPC: A61F7/12
CPC classification number: A61F7/12 , A61F7/123 , A61F2007/0054 , A61F2007/0056 , A61F2007/0096 , A61F2007/126
Abstract: A transatrial intravascular temperature management catheter has a lower heat exchange segment positionable in the inferior vena cava and an upper heat exchange segment positionable in the superior vane cava, with a connecting segment lying between the two and positionable in the right atrium. A temperature sensor on the distal tip of the upper heat exchange segment provides accurate core body temperature signals for feedback purposes since the blood flowing past the sensor has not yet reached the heat exchange segment.
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Patent Agency Ranking
公开(公告)号：US09320678B2
公开(公告)日：2016-04-26
申请号：US14042382
申请日：2013-09-30
Applicant: ZOLL Circulation, Inc.
Inventor： Uday Kiran V. Illindala
CPC classification number: A61H31/006 , A61H2201/1207 , A61H2201/1215 , A61H2201/1664 , A61H2201/5043
Abstract: A chest compression device includes a piston to apply compression to the sternum and incorporates leaf springs simultaneously driven by the piston to apply lateral compression to the thorax during chest compressions. A motor in the chest compression device provides motive power to cyclically extend and contract the piston to provide therapeutic chest compressions. One end of each leaf spring is operably connected to the piston and the other end of each leaf spring is secured to the backboard/base or to a support leg of the chest compression device such that during extension of the piston, each leaf spring is compressed against the device base or leg which causes the springs to flex and provide lateral compression of the patient's thorax in addition to the sternal compression of the piston.
Abstract translation: 胸部压缩装置包括活塞，以对胸骨施加压力，并且包括由活塞同时驱动的板簧，以在胸部按压期间向胸部施加横向压缩。 胸部压缩装置中的电动机提供动力以循环地延伸和收缩活塞以提供治疗性胸部按压。 每个板簧的一端可操作地连接到活塞，并且每个板簧的另一端固定到背板/基座或胸部压缩装置的支撑腿，使得在活塞延伸期间，每个板簧被压缩 除了活塞的胸骨压缩之外，还可以使装置底座或腿部弹簧弹性弯曲并提供患者胸部的侧向压缩。
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公开(公告)号：US09314367B2
公开(公告)日：2016-04-19
申请号：US13888149
申请日：2013-05-06
Applicant: ZOLL CIRCULATION, INC.
Inventor： Jeffrey Callister , Paul M. Stull , Andrew E. Wu , David J. Scott
CPC classification number: A61F7/12 , A61F7/007 , A61F7/0085 , A61F2007/0054 , A61F2007/0075 , A61F2007/0086 , A61F2007/0096 , A61F2007/126 , G05D23/1925
Abstract: Systems and methods for accurate temperature modification of a patient, or selected regions thereof, including inducing hypothermia. The temperature modification is accomplished using an in-dwelling heat exchange catheter within which a fluid heat exchange medium circulates. A heat exchange cassette attached to the circulatory flow lines of the catheter, the heat exchange cassette being sized to engage a cavity within a control unit. A temperature measurement scheme for obtaining body core temperature is provided, including methods of obtaining and analyzing temperature data to provide feedback to the control unit for use in controlling the heating and cooling of the heat exchange medium so as to heat or cool a patient to a desired target temperature.
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公开(公告)号：US20160058931A1
公开(公告)日：2016-03-03
申请号：US14936507
申请日：2015-11-09
Applicant: ZOLL Circulation, Inc.
Inventor： Michael W. Dae , Timothy R. MacHold
IPC: A61M1/10
CPC classification number: A61M1/1086 , A61F7/10 , A61F7/123 , A61F2007/0056 , A61F2007/0095 , A61F2007/126 , A61M1/106 , A61M1/107 , A61M1/1072 , A61M1/1074 , A61M1/125 , A61M19/00 , A61M2205/3606 , A61M2230/04
Abstract: Devices, systems and methods for treating disorders characterized by low cardiac output. The devices, systems and methods use intra-aortic balloon counterpulsation in combination with hypothermia of all or a portion of a human or veterinary patient's body to improve coronary perfusion and cardiac output. To effect the hypothermia, a heat exchange catheter may be positioned in the a patient's vasculature separately from the intra-aortic balloon counterpulsation catheter. Alternatively, a combination Intra-aortic balloon counterpulsation/heat exchange catheter may be utilized. Such combination catheter comprises a) a catheter sized for insertion into the aorta, b) a counterpulsation balloon and c) a heat exchanger. A drive/control system receives temperature and electrocardiograph signals and drives the inflation/deflation of the counterpulsation balloon as well as the heating/cooling of the heat exchanger.
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公开(公告)号：US09259349B2
公开(公告)日：2016-02-16
申请号：US14162118
申请日：2014-01-23
Applicant: ZOLL CIRCULATION, INC.
Inventor： Blair D. Walker , Scott M. Evans , David P. Balding , Peter Barker
IPC: A61F7/12 , A61M31/00 , A61M25/00 , A61M25/02 , A61B17/00 , A61F7/00 , A61M1/36 , A61M5/44 , A61M25/10
CPC classification number: A61F7/12 , A61B2017/00084 , A61F7/123 , A61F2007/0054 , A61F2007/126 , A61M1/369 , A61M5/44 , A61M25/00 , A61M25/002 , A61M25/003 , A61M25/0032 , A61M25/02 , A61M25/10 , A61M25/1011 , A61M2025/0036 , A61M2025/1013 , A61M2205/36 , A61M2205/366
Abstract: A kit of parts comprises a system and instructions for use for controlling patient temperature which uses a central venous line catheter having a heat exchange element. The central venous line catheter is provided with one or more lumens for providing access to the central blood supply of the patient, and with additional lumens for communicating heat exchange fluid to the heat exchange element. Heat exchange fluid temperature is controlled through a feed back loop in which patient temperature is sensed and used to control a temperature control unit comprising a heating device and/or a cooling device in heat exchange relationship with the heat exchange fluid. A tubing set transports the heat exchange fluid between the central venous line and the temperature control unit, with a pump serving to circulate the fluid in a closed fluid circuit in the system.
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公开(公告)号：US20160022483A1
公开(公告)日：2016-01-28
申请号：US14873473
申请日：2015-10-02
Applicant: Zoll Circulation, Inc.
Inventor： Kenneth A. Collins
IPC: A61F7/12
CPC classification number: A61F7/12 , A61B2017/00084 , A61F2007/0056 , A61F2007/101 , A61F2007/126
Abstract: A method for exchanging heat with a patient's spinal column incident to spinal surgery or to relieve a patient for a hypoxia condition of the spine. A closed loop heat exchange catheter is percutaneously advanced into the retroperitoneal space of the patient or into the vasculature, and then heat exchange fluid is circulated through the catheter to cool the spinal column.
Abstract translation: 一种与患者脊柱交换热量进入脊柱手术或减轻患者脊柱缺氧状况的方法。 闭环热交换导管经皮推进到患者的腹膜后空间或脉管系统中，然后热交换流体循环通过导管以冷却脊柱。
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