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公开(公告)号:US20230285636A1
公开(公告)日:2023-09-14
申请号:US17968476
申请日:2022-10-18
Inventor: Eben Alsberg , Anna D. Dikina , Marsha W. Rolle
CPC classification number: A61L27/3882 , A61L27/3804 , A61L27/54 , C12N5/0075 , A61L2300/414 , A61L2300/602 , A61L2300/62 , A61L2400/12 , A61L2430/22 , C12N2513/00 , C12N2531/00
Abstract: A modular engineered tissue construct includes a plurality of fused self-assembled, scaffold-free, high-density cell aggregates. At least one cell aggregate includes a plurality of cells and a plurality of biocompatible and biodegradable nanoparticles and/or microparticles that are incorporated within the cell aggregates. The nanoparticles and/or microparticles acting as a bulking agent within the cell aggregate to increase the cell aggregate size and/or thickness and improve the mechanical properties of the cell aggregate as well as to deliver bioactive agents.
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公开(公告)号:US20230198040A1
公开(公告)日:2023-06-22
申请号:US18113130
申请日:2023-02-23
Applicant: Worcester Polytechnic Institute , Ascend Elements, Inc.
Inventor: Yan Wang , Diran Apelian , Haiyang Zou
CPC classification number: H01M10/54 , C22B23/0438 , C22B23/0423 , C22B26/22 , C22B23/043 , C22B1/24 , C22B7/007
Abstract: Cathode material from exhausted lithium ion batteries are dissolved in a solution for extracting the useful elements Co (cobalt), Ni (nickel), Al (Aluminum) and Mn (manganese) to produce active cathode materials for new batteries. The solution includes compounds of desirable materials such as cobalt, nickel, aluminum and manganese dissolved as compounds from the exhausted cathode material of spent cells. Depending on a desired proportion, or ratio, of the desired materials, raw materials are added to the solution to achieve the desired ratio of the commingled compounds for the recycled cathode material for new cells. The desired materials precipitate out of solution without extensive heating or separation of the desired materials into individual compounds or elements. The resulting active cathode material has the predetermined ratio for use in new cells, and avoids high heat typically required to separate the useful elements because the desired materials remain commingled in solution.
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公开(公告)号:US20230181177A1
公开(公告)日:2023-06-15
申请号:US18065549
申请日:2022-12-13
Inventor: David M. Harlan , Yihao Zheng , Sambra D. Redick , Katerina Angjeli , Sally C. Kent
CPC classification number: A61B10/0266 , B23B31/20
Abstract: Described are a micro punch cutting tool and associated method that can be used under a microscope to accurately excise a targeted piece of material on a micron or millimeter scale. An example device for targeted material excision from a tissue sample includes a support defining an opening and providing a region below the opening for positioning a tissue sample. A tissue stabilizer is receivable in the opening and defines a shape that complements a shape of the support. A cutting tool assembly receivable in the tissue stabilizer includes a hollow cutter having a bore and is movable relative to the tissue stabilizer to cause the cutter to excise material from the tissue sample when the tissue sample is positioned below the opening of the support. Movement of the cutting tool assembly is guided by a helical groove in the tissue stabilizer engaging a protrusion of the cutting tool assembly.
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公开(公告)号:US11666258B2
公开(公告)日:2023-06-06
申请号:US16523147
申请日:2019-07-26
Applicant: WORCESTER POLYTECHNIC INSTITUTE
Inventor: Mina Shojaeizadeh , Soussan Djamasbi , Randy C. Paffenroth , Andrew C. Trapp
CPC classification number: A61B5/163 , A61B3/113 , G06F3/013 , G06F3/017 , G06F9/542 , G06F18/214 , G06N20/00 , G06T7/20 , G06V40/19
Abstract: A visual tracking system, comprises an eye-tracking device and a cognitive load detection device disposed in electrical communication with the eye-tracking device, the cognitive load detection device comprising a controller having a memory and a processor. The controller is configured to receive eye-movement data from the eye-tracking device, the eye-movement data comprising pupil dilation event data and at least one of saccade event data and fixation event data, apply a classification function to the eye-movement data to detect a cognitive load associated with the eye-movement data and corresponding to a visual location of a field of view of the user, and output a notification regarding the cognitive load associated with the eye-movement data.
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公开(公告)号:US11590406B2
公开(公告)日:2023-02-28
申请号:US15952451
申请日:2018-04-13
Applicant: Worcester Polytechnic Institute
Inventor: Jacob J. Billington , Jonathan D. Comden , Sean J. Regan , Thomas C. Roberti , Christopher A. Brown
Abstract: A ski binding reduces a likelihood of injury to the anterior cruciate ligament (ACL) and the tibia is accomplished by absorption in the binding to limit loads transmitted through the boot-binding interface. Release based on an injury threshold includes a binding response tower attached to the ski and adapted for selective engagement with the ski, such that the binding response tower permits biased vertical and lateral horizontal displacement, prior to a release threshold. The binding is in communication with the boot heel and is adapted for slideable engagement in response to vertical and lateral forces exerted from the boot heel. The binding response tower adapted to disengage, or release upon reaching at least one a predetermined lateral displacement or a predetermined vertical displacement, such as when the boot heel is forced sufficiently sideways or upwards due to skier movement that would tend to cause an ACL injury.
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公开(公告)号:US11566186B2
公开(公告)日:2023-01-31
申请号:US17055014
申请日:2019-05-15
Applicant: Worcester Polytechnic Institute
Inventor: Michael T. Timko , Geoffrey A. Tompsett , Azadeh Zaker
Abstract: A petroleum refining method for upgrading petroleum products improves the efficiency and reduces the costs of upgrading oils, such as lipids, bitumen, crude oil, fracking oils, synthetic oils, and other feeds, to produce useful fuels and chemical precursor streams. Usage of a specific type of zeolite (ZSM-5) catalyst, supercritical water to control coke formation, and a specific response to phase behavior and other catalytic effects optimize the process. A prescribed set of reactor conditions employing supercritical water increases activity of the catalyst in industrial reactions.
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公开(公告)号:US20220332003A1
公开(公告)日:2022-10-20
申请号:US17721553
申请日:2022-04-15
Applicant: Worcester Polytechnic Institute
Inventor: Berk Calli
IPC: B26D3/10
Abstract: A robotic cutting device includes a cutting tool responsive to a mobile actuator adapted to apply a cutting force in a 3-dimensional (3D) space, and scanning logic configured to identify a cutting path denoted on an article for cutting. Using the cutting path, a mobile actuator is responsive to positioning logic for disposing the cutting tool along the cutting path for performing a prescribed cut on the article. The mobile actuator is a robotic arm responsive to an independent coordinate frame based on a position and orientation of a mobility vehicle supporting the mobile actuator. The mobility vehicle is typically a tracked or all-terrain capable chassis adapted to be disposed adjacent to the article such that the article is within range of the actuator. The mobility vehicle transports the robotic cutting device adjacent to the article to be cut, such that the cutting path is within reach.
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公开(公告)号:US20220325378A1
公开(公告)日:2022-10-13
申请号:US17719080
申请日:2022-04-12
Applicant: Worcester Polytechnic Institute
Inventor: Yan Wang , Jiahui Hou , Xiaotu MA , Jinzhao Fu
Abstract: Lithium recycling from expended Li-Ion batteries occurs thought selective recovery of lithium charge materials from a recycling stream including transition metals used for the charge material. Li recovery includes dissolving the lithium based charge material in an organic acid having a resistance or lack of affinity to dissolution of transition metals, and distilling a leach solution formed from the dissolved charge material for generating a powder including lithium and trace impurities of the transition metals. Sintering of the generated powder forms lithium carbonate and carbonates of the trace impurities that eluded the selective leach, however, since the trace impurities are insoluble in water, the lithium carbonate is recoverable by water washing.
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公开(公告)号:US20220325184A1
公开(公告)日:2022-10-13
申请号:US17713818
申请日:2022-04-05
Applicant: Worcester Polytechnic Institute
Inventor: Michael T. Timko , Geoffrey A. Tompsett , Azadeh Zaker
Abstract: Methods are described herein for upgrading ad refining hydrocarbons, and producing at least one petrochemical product, the method including: preparing a reaction mixture by adding at least two of: a quantity of bioethanol, a quantity of hydrocarbon, and a quantity of water to a reactor containment; combining the reaction mixture with a quantity of catalyst in the reactor containment; applying reaction conditions to the reactor containment thereby generating supercritical conditions for the reaction mixture and obtaining a product mixture; and extracting at least one petrochemical product from the product mixture.
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公开(公告)号:US20220311068A1
公开(公告)日:2022-09-29
申请号:US17841152
申请日:2022-06-15
Applicant: Worcester Polytechnic Institute
Inventor: Yan Wang , Eric Gratz , Qina Sa , Zhangfeng Zheng , Joseph Heelan , Kee-Chan Kim
Abstract: Cathode material from exhausted lithium ion batteries are dissolved in a solution for extracting the useful elements Co (cobalt), Ni (nickel), Al (Aluminum) and Mn (manganese) to produce active cathode materials for new batteries. The solution includes compounds of desirable materials such as cobalt, nickel, aluminum and manganese dissolved as compounds from the exhausted cathode material of spent cells. Depending on a desired proportion, or ratio, of the desired materials, raw materials are added to the solution to achieve the desired ratio of the commingled compounds for the recycled cathode material for new cells. The desired materials precipitate out of solution without extensive heating or separation of the desired materials into individual compounds or elements. The resulting active cathode material has the predetermined ratio for use in new cells, and avoids high heat typically required to separate the useful elements because the desired materials remain commingled in solution.
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