-
341.
公开(公告)号:US20250014721A1
公开(公告)日:2025-01-09
申请号:US18761131
申请日:2024-07-01
Inventor: ZiYu Fan , Jianming Liang
IPC: G16H30/40 , G06T5/40 , G06T5/92 , G06V10/26 , G06V10/32 , G06V10/764 , G06V10/774 , G06V10/82
Abstract: A generic unified deep model for learning from multiple tasks, in the context of medical image analysis includes means for receiving a training dataset of medical images; training the AI model to generate a trained AI model using a pre-processing operation, a Swin Transformer-based segmentation operation, and a post-processing operation, in which application of a Non-Maximum Suppression (NMS) algorithm generates object detection and classification output parameters for the AI model by removing overlapping detections and selecting a best set of detections according to a determined confidence score for the detections remaining; and outputting the trained AI model for use with medical image analysis.
-
公开(公告)号:US20250001384A1
公开(公告)日:2025-01-02
申请号:US18732594
申请日:2024-06-03
Inventor: Quan QING , Ching-wei TSAO , Peiming ZHANG
Abstract: The present disclosure provides an apparatus for synthesizing a biopolymer, a method for preparing an apparatus for synthesizing a biopolymer, and a method of synthesizing a biopolymer.
-
公开(公告)号:US20240425507A1
公开(公告)日:2024-12-26
申请号:US18828570
申请日:2024-09-09
Inventor: Jian Li
IPC: C07D471/14 , C07D471/04 , C07D471/22 , C07D493/22 , C07D495/14 , C07D495/22 , C09K11/06 , H10K50/11 , H10K85/60 , H10K101/10
Abstract: Thermally assisted delayed fluorescent materials with triad-type materials for use in full color displays and lighting applications are provided.
-
公开(公告)号:US12171615B2
公开(公告)日:2024-12-24
申请号:US17329649
申请日:2021-05-25
Inventor: Barbara Smith , Joel Barkley , Christopher Miranda
Abstract: A device comprises a cannula having a first end, a second end, and a channel between the first end and the second end; an imaging probe couplable to the first end of the cannula, where the imaging probe includes: a transducer, and a reflective surface; and a biopsy device coupled to the cannula, where the biopsy device is configured to collect a tissue sample from an organ of a patient.
-
公开(公告)号:US20240418570A1
公开(公告)日:2024-12-19
申请号:US18748614
申请日:2024-06-20
Inventor: Yu Yao , Chao Wang , Chu Wang , Jing Bai , Ali Basiri , Xiahui Chen
Abstract: A method of fabricating a polarization sensor is described. It includes a quarter-wave plate to convert circularly polarized light into linearly polarized light. The quarter-wave plate is realized as a metasurface. The sensor also includes a linear polarizer to analyze the light generated by the quarter wave plate, and a photodetector to receive the analyzed light. The sensor may be combined with other linear polarization sensors to form a sensor capable of complete measurement of the polarization state of incident light.
-
公开(公告)号:US20240412367A1
公开(公告)日:2024-12-12
申请号:US18674642
申请日:2024-05-24
Inventor: Jianming Liang
IPC: G06T7/00 , G06T7/11 , G06V10/764 , G06V10/778
Abstract: A system implements self-supervised learning through contrastive learning using an image transformer. The transformer receives medical images for training an Artificial Intelligence (AI) model, and executes a first cropping and prediction operation by (i) cropping a first patch P from a first random location L from an image A selected from the plurality of medical images and (ii) training a classification head to predict that the first patch P is part of the image A. The transformer executes a second cropping and prediction operation by (iii) cropping a second patch P from a second random location L from the image A selected from the plurality of medical images and (iv) training the classification head to predict that the second patch P forms no part of an image B selected from the plurality of medical images. The transformer issues a determination that the image B is different than the image A.
-
公开(公告)号:US20240410826A1
公开(公告)日:2024-12-12
申请号:US18691592
申请日:2022-09-27
Inventor: Shaopeng Wang , Pengfei Zhang
Abstract: Provided herein are methods of detecting single molecules that include binding single molecules in a sample solution to a first surface of an optically transparent substrate include the optically transparent substrate is free of a metallic coating. In some embodiments, the methods include irradiating the first surface of the substrate with an incident light having an incident angle selected to achieve total internal reflection of the incident light, thereby scattering light from the first surface and from the single molecules bound to the surface in which a wavelength of the incident light is between 10 nm and 350 μm and the optically transparent substrate has a refractive index at the wavelength of the incident light exceeding that of the sample solution, and collecting an image that captures interference between evanescent light scattered from the single molecules and the first surface. Systems and additional methods are also provided.
-
348.
公开(公告)号:US20240409669A1
公开(公告)日:2024-12-12
申请号:US18701901
申请日:2022-10-20
Inventor: Nicholas Stephanopoulos , Yang Xu , Petr Sulc , Hao Yan , Rong Zheng , Abhay Prasad
IPC: C07K19/00 , A61K38/00 , A61P31/14 , C07K14/005
Abstract: The present disclosure relates to DNA-peptide hybrid molecules. In some embodiments, the DNA-peptide hybrid molecules comprise target-specific binding peptides which selectively bind to SARS-COV-2 surface glycoprotein. Methods of using DNA-peptide hybrid molecules in the treatment of SARS-COV-2 infection are also provided.
-
公开(公告)号:US12145152B1
公开(公告)日:2024-11-19
申请号:US18690486
申请日:2021-09-10
Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY , HANGZHOU VANTRONICS BIOTECHNOLOGY CO. LTD.
Inventor: Hanging Jiang , Chao Liang , Senwei Xu
IPC: B01L3/00
Abstract: A pneumatic-driven fluidic cartridge and systems and methods for operating the same. The cartridge includes a substrate layer, an actuator layer, and an elastic layer. A fluid channel formed in a surface of the substrate layer includes a first chamber and a second chamber separated by a block section. The actuator layer includes a lever positioned to extend across the block section. The elastic layer is positioned between the substrate layer and the actuator layer. The lever applies a force to the elastic layer restricts fluid flow from the first chamber to the second chamber and is configured to bend outwardly opening a channel between the block section and the elastic layer exceeds the first threshold pressure.
-
公开(公告)号:US20240379192A1
公开(公告)日:2024-11-14
申请号:US18691489
申请日:2022-09-30
Inventor: Neal W. Woodbury , Robayet Chowdhury , Alexander T. Taguchi
Abstract: Systems and methods for using machine learning to improve disease diagnostics are provided. A method can include obtaining, using a peptide array, peptide sequence data and peptide binding values from one or more samples, wherein the peptide sequence data and the peptide binding values correspond to a plurality of conditions; for each of the one or more samples, normalizing the peptide binding values according to a median binding value of peptides associated with the peptide array; and training a regressor using dense compact representations of the peptide sequence data and peptide binding values. The method can further include providing an output of the regressor to a classifier, wherein the classifier is configured to determine whether the patient has one of the plurality of conditions based on the output of the regressor.
-
-
-
-
-
-
-
-
-