公开(公告)号：US10888391B2

公开(公告)日：2021-01-12

申请号：US15577924

申请日：2015-05-29

申请人： Ablacon Inc.

发明人： Peter Ruppersberg

IPC分类号： A61B90/00 ,  A61B18/14 ,  G01L5/166 ,  A61B5/00 ,  A61B17/00 ,  A61B18/00

摘要： The present invention concerns an elongated medical device (1) suitable for intravascular insertion. Said device comprising a flexible elongated body (2) having a distal portion (3) with a distal end (4) and a proximal portion (5) and an optic force sensing assembly (20) disposed within said flexible elongated body (2) proximate said distal end. The optical force sensing assembly (20) comprises a light source (30), which defines a linear optical light source axis (A), and an optical sensor (40), which faces the light source (30) and which defines a linear optical sensor axis (B) and whereat the optical sensor (40) is arranged in a distance (d0, d1) to the light source along the optical sensor axis (B), a mounting assembly (50) for the optical sensor (40) and the light source (30) which allows for relative movement of the light source (30) against the optical sensor (40) at least in the directions X, Y, Z of the Cartesian coordinate system, wherein direction Z is parallel to the direction of the optical sensor axis (B) at least in an initial state of the optical force sensing assembly (20) and whereby X and Y directions are perpendicular to each other as well as perpendicular to Z direction.

公开(公告)号：US20200345261A1

公开(公告)日：2020-11-05

申请号：US16931844

申请日：2020-07-17

申请人： Ablacon Inc.

发明人： Philip Haeusser ,  Peter Ruppersberg

IPC分类号： A61B5/04 ,  A61B5/00 ,  A61B5/044 ,  A61B5/0408 ,  A61B5/042 ,  A61B5/046

摘要： Disclosed are various examples and embodiments of systems, devices, components and methods configured to detect a location of a source of at least one cardiac rhythm disorder in a patient's heart. In some embodiments, electrogram signals are acquired from a patient's body surface, and subsequently normalized, adjusted and/or filtered, followed by generating a two-dimensional spatial map, grid or representation of the electrode positions, processing the amplitude-adjusted and filtered electrogram signals to generate a plurality of three-dimensional electrogram surfaces corresponding at least partially to the 2D map, one surface being generated for each or selected discrete times, and processing the plurality of three-dimensional electrogram surfaces through time to generate a velocity vector or other type of map using one or more of optical flow, video tracking analysis, motion capture analysis, motion estimation analysis, data association and segmentation tracking analysis, particle tracking analysis, and single-particle tracking analysis methods corresponding at least partially to the 2D map. Trained atrial discriminative machine learning models that facilitate the foregoing systems and methods, and that provide predictions or results concerning a patient's condition, are also disclosed.

公开(公告)号：US10806343B2

公开(公告)日：2020-10-20

申请号：US16168235

申请日：2018-10-23

申请人： Ablacon Inc.

发明人： Peter Ruppersberg

IPC分类号： A61B5/00 ,  A61B5/04 ,  A61B5/042 ,  A61B5/044 ,  A61B18/14 ,  A61B5/0402 ,  A61B18/00 ,  A61B90/00

摘要： Disclosed are various examples and embodiments of systems, devices, components and methods configured to detect a location of a source of at least one cardiac rhythm disorder in a patient's heart. In some embodiments, electrogram signals are acquired from inside a patient's heart, and subsequently normalized, adjusted and/or filtered, followed by generating a two-dimensional spatial map, grid or representation of the electrode positions, processing the amplitude-adjusted and filtered electrogram signals across the 2D representation to generate a plurality of three-dimensional electrogram surfaces, one surface being generated for each or selected discrete times, and processing the plurality of three-dimensional electrogram surfaces across the 2D map through time to generate a velocity vector map. The resulting velocity vector map is configured to reveal the location of the source of the at least one cardiac rhythm disorder, which may be, by way of example, an active rotor in a patient's myocardium and atrium.

公开(公告)号：US20190142271A1

公开(公告)日：2019-05-16

申请号：US16231883

申请日：2018-12-24

申请人： Ablacon Inc.

发明人： Peter Ruppersberg

IPC分类号： A61B5/00 ,  A61B5/044 ,  A61B5/04 ,  A61B5/042 ,  A61B18/14 ,  A61B5/0402

摘要： Disclosed are various examples of embodiments of systems, devices, components and methods configured to detect a location of a source of at least one cardiac rhythm disorder in a patient's heart. In some embodiments, electrogram signals are acquired from inside a patient's heart, and subsequently normalized, adjusted and/or filtered, followed by generating a two-dimensional (2D) spatial map, grid or representation of the electrode positions, processing the amplitude-adjusted and filtered electrogram signals to generate a plurality of three-dimensional electrogram surfaces corresponding at least partially to the 2 D grid, one surface being generated for each or selected discrete times, and processing the plurality of three-dimensional electrogram surfaces through time to generate a velocity vector map corresponding at least partially to the 2 D grid. The resulting velocity vector map is configured to reveal the location of the source of the at least one cardiac rhythm disorder, which may be, by way of example, an active rotor in a patient's myocardium and atrium.

公开(公告)号：US20190090746A1

公开(公告)日：2019-03-28

申请号：US16168235

申请日：2018-10-23

申请人： Ablacon Inc.

发明人： Peter Ruppersberg

IPC分类号： A61B5/00 ,  A61B5/04 ,  A61B5/042 ,  A61B5/044 ,  A61B5/0402 ,  A61B18/14 ,  A61B18/00 ,  A61B90/00

CPC分类号： A61B5/0006 ,  A61B5/04011 ,  A61B5/04012 ,  A61B5/04017 ,  A61B5/04028 ,  A61B5/0422 ,  A61B5/044 ,  A61B5/6852 ,  A61B5/6858 ,  A61B5/742 ,  A61B18/1492 ,  A61B2018/00267 ,  A61B2018/00351 ,  A61B2018/00577 ,  A61B2018/1467 ,  A61B2090/065

摘要： Disclosed are various examples and embodiments of systems, devices, components and methods configured to detect a location of a source of at least one cardiac rhythm disorder in a patient's heart. In some embodiments, electrogram signals are acquired from inside a patient's heart, and subsequently normalized, adjusted and/or filtered, followed by generating a two-dimensional spatial map, grid or representation of the electrode positions, processing the amplitude-adjusted and filtered electrogram signals across the 2D representation to generate a plurality of three-dimensional electrogram surfaces, one surface being generated for each or selected discrete times, and processing the plurality of three-dimensional electrogram surfaces across the 2D map through time to generate a velocity vector map. The resulting velocity vector map is configured to reveal the location of the source of the at least one cardiac rhythm disorder, which may be, by way of example, an active rotor in a patient's myocardium and atrium.

公开(公告)号：US20180116595A1

公开(公告)日：2018-05-03

申请号：US15793594

申请日：2017-10-25

申请人： Ablacon Inc.

发明人： Peter Ruppersberg

IPC分类号： A61B5/00 ,  A61B5/042

CPC分类号： A61B5/6858 ,  A61B5/0422 ,  A61B2562/0209 ,  A61B2562/046 ,  A61B2562/125 ,  A61B2562/164

摘要： Disclosed are various examples and embodiments of a cardiac mapping catheter configured for electrophysiological (EP) mapping and suitable for intravascular insertion in a patient's heart, and methods of making same. The cardiac mapping catheter comprises a plurality support arms having electrodes disposed thereon. Various configurations of the cardiac mapping catheter are described and disclosed which provide improved spatial resolution and sensing of EP signals acquired from inside a patient's heart.