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公开(公告)号:USD921212S1
公开(公告)日:2021-06-01
申请号:US29720106
申请日:2020-01-09
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公开(公告)号:US10967043B2
公开(公告)日:2021-04-06
申请号:US16436401
申请日:2019-06-10
IPC分类号: A61K38/00 , A61K38/10 , A61K38/12 , A61K45/06 , A61K38/04 , A61K31/53 , A61K31/192 , A61K31/352 , A61K31/4468 , A61K31/501 , A61K31/519 , A61K31/7004 , A61K9/28 , A61K31/194 , A61K33/42
摘要: This invention provides a method of colonic cleansing.
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公开(公告)号:US20200297684A1
公开(公告)日:2020-09-24
申请号:US16822831
申请日:2020-03-18
IPC分类号: A61K31/203 , A61K31/327 , A61P17/10
摘要: Topical pharmaceutical compositions comprise a combination of retinoid and an antibacterial agent. In particular, a topical composition comprises tretinoin and benzoyl peroxide. Such compositions are used for treating acne vulgaris.
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公开(公告)号:US10653656B2
公开(公告)日:2020-05-19
申请号:US16108942
申请日:2018-08-22
发明人: Varsha Bhatt , Radhakrishnan Pillai
IPC分类号: A61K31/203 , A61K9/06 , A61K47/32 , A61K47/44 , A61P17/10 , A61K47/14 , A61K47/10 , A61K47/18 , A61K47/36
摘要: In one aspect, topical pharmaceutical compositions for treating a skin condition or disorder are provided. In some embodiments, the topical pharmaceutical composition is formulated as a lotion and comprises a therapeutically effective amount of an active agent; a viscosity increasing agent; a polymeric emulsifier; and an oil component. In some embodiments, the topical pharmaceutical composition comprises tretinoin.
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公开(公告)号:US10597424B2
公开(公告)日:2020-03-24
申请号:US16150703
申请日:2018-10-03
发明人: Kunwar Shailubhai
摘要: This invention provides novel guanylate cyclase C (GC-C) agonists and their therapeutic use. The agonists may be used either alone or in combination with one or more additional agents.
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36.
公开(公告)号:US20200009215A1
公开(公告)日:2020-01-09
申请号:US16577880
申请日:2019-09-20
摘要: This invention provides a method to prevent, control, and/or treat opioid induced dysfunctions comprising administering to a patient in need a guanylate cyclase receptor agonist (GCRA) peptide. Compositions comprising guanylate cyclase receptor agonist (GCRA) peptides, methods of making, and methods of treatment are also disclosed.
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公开(公告)号:US10421787B2
公开(公告)日:2019-09-24
申请号:US15405787
申请日:2017-01-13
发明人: Juncai Bai , Ruoping Zhang , Jun Jian , Junfeng Zhou , Qiao Zhao , Guoquing Zhang , Kunwar Shailubhai , Stephen Comiskey , Rong Feng
IPC分类号: C07K7/64 , C07K7/08 , C07K14/195
摘要: The invention provides processes of preparing a peptide including a GCC agonist sequence selected from the group consisting of SEQ ID NOs: 1-249 described herein.
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公开(公告)号:US20230111568A1
公开(公告)日:2023-04-13
申请号:US17913844
申请日:2021-03-24
IPC分类号: A61K31/437 , A61P1/16 , A61P25/28 , A61K31/7016 , A61K9/20 , A61K9/28
摘要: Provided herein are solid dispersions comprising rifaximin and methods of using the same for the treatment of Overt Hepatic Encephalopathy and complications associated with cirrhosis.
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公开(公告)号:US20230087566A1
公开(公告)日:2023-03-23
申请号:US17909028
申请日:2021-03-15
IPC分类号: A61B17/32
摘要: Probes for delivering ultrasonic energy and related methods. The probe includes a shank having a shaft coupling a proximal end to a distal end. The shank is configured to propagate ultrasonic energy from the proximal end to a tip of the distal end in a propagation direction parallel to a longitudinal axis disposed along a centerline of the shank. The tip may be positioned to substantially coincide with a displacement antinode position when the ultrasonic energy corresponds to odd integer multiples of a quarter wavelength of a resonance frequency. Multiple grooves within the shaft are configured to create multiple cavitation volumes in a medium proximate to the shank responsive to the ultrasonic energy. The multiple grooves include a second groove intervening between a first groove and the proximal end. The first groove is positioned at a distance of an integer multiple of a half-wavelength of the resonance frequency.
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公开(公告)号:US20230086282A1
公开(公告)日:2023-03-23
申请号:US17993817
申请日:2022-11-23
IPC分类号: A61K31/573 , A61K9/00 , A61K45/06 , A61K9/06 , A61K31/192 , A61K47/26 , A61K9/12 , A61K47/14 , A61K47/44 , A61K9/107 , A61K31/4436
摘要: Topical pharmaceutical compositions comprise a combination of a corticosteroid a retinoid; and methods for treating psoriasis with same.
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