公开(公告)号：US20070112372A1

公开(公告)日：2007-05-17

申请号：US11281128

申请日：2005-11-17

Applicant: Stephen Sosnowski ,  David Rosenthal

Inventor： Stephen Sosnowski ,  David Rosenthal

IPC: A61M29/00

CPC classification number: A61F2/01 ,  A61F2/82 ,  A61F2002/016 ,  A61F2210/0004 ,  A61F2230/0006 ,  A61F2230/0078 ,  A61F2230/0091 ,  A61F2250/0031

Abstract: Novel enhanced products and processes for trapping emboli utilize self-expanding skeletons and biodegradable polymer systems, for example stent-like Nitinol® elements and PLGA, to address longstanding issues related to thrombus capture without deleterious impacts on the vasculature or other negative artifacts of the procedure by at least partial post-use dissolution in situ. Drug coating and elution technologies are included as would be known to those skilled in the art.

Abstract translation: 用于捕获栓塞的新型增强产品和方法利用自膨胀骨架和可生物降解的聚合物体系，例如支架样蛋白质元素和PLGA，以解决与血栓捕获相关的长期问题，而不会对脉管系统或其他负面假象产生有害影响 该程序至少部分使用后溶解于原位。 包括本领域技术人员已知的药物包衣和洗脱技术。

公开(公告)号：US07088434B2

公开(公告)日：2006-08-08

申请号：US10641386

申请日：2003-08-13

Applicant: Mary L. Johnson ,  Alvan Gilbertson ,  David Rosenthal

Inventor： Mary L. Johnson ,  Alvan Gilbertson ,  David Rosenthal

IPC: G01N21/00

CPC classification number: G01N21/87 ,  G01N21/8806

Abstract: An apparatus, system and method for providing spot lighting for observing a gemstone is presented. In particular, the spot lighting provided by the invention allows for observing of the fire of a gemstone, i.e. the visible effects of light dispersion into separate colors. The apparatus includes a tube for receiving a portion of a multi-spectral light source, and a mask coupled to the tube for blocking other portions of the light source. By selecting the proper tube dimensions and aligning the tube with both the light source at an inlet and a gemstone at an outlet, the spot lighting source provides direct lighting for isolating and accentuating the effects of fire.

公开(公告)号：US20050036131A1

公开(公告)日：2005-02-17

申请号：US10641386

申请日：2003-08-13

Applicant: Mary Johnson ,  Alvan Gilbertson ,  David Rosenthal

Inventor： Mary Johnson ,  Alvan Gilbertson ,  David Rosenthal

IPC: G01N21/87 ,  G01N21/00

CPC classification number: G01N21/87 ,  G01N21/8806

Abstract: An apparatus, system and method for providing spot lighting for observing a gemstone is presented. In particular, the spot lighting provided by the invention allows for observing of the fire of a gemstone, i.e. the visible effects of light dispersion into separate colors. The apparatus includes a tube for receiving a portion of a multi-spectral light source, and a mask coupled to the tube for blocking other portions of the light source. By selecting the proper tube dimensions and aligning the tube with both the light source at an inlet and a gemstone at an outlet, the spot lighting source provides direct lighting for isolating and accentuating the effects of fire.

Abstract translation: 提出了一种用于提供用于观察宝石的点光的装置，系统和方法。 特别地，由本发明提供的点状照明允许观察宝石的火焰，即将光散射的可见效果分解成分开的颜色。 该装置包括用于接收多光谱光源的一部分的管和耦合到管的掩模，用于阻挡光源的其它部分。 通过选择适当的管尺寸并将管与入口处的光源和出口处的宝石对准，点光源提供用于隔离和强调火灾影响的直接照明。

公开(公告)号：US06612976B2

公开(公告)日：2003-09-02

申请号：US09879551

申请日：2001-06-12

Applicant: David Rosenthal ,  Brian Gannon

Inventor： David Rosenthal ,  Brian Gannon

IPC: A61N500

CPC classification number: A61K51/1272 ,  A61N5/1002 ,  A61N2005/1019

Abstract: This invention involves radioactive medical devices for inhibiting an undesirable hyperplastic response in biological tissue, and a method for making the radioactive medical devices. In a first preferred embodiment, a medical device for inhibiting a hyperplastic response in biological tissue generally comprises polymeric hydrocarbon molecules forming the medical device and a salt or an acid of a radioactive isotope occluded within the polymeric hydrocarbon molecules. In a second preferred embodiment, the medical device comprises a thrombogenic sponge having a radioisotope trapped within the structure of the sponge. Also in a preferred embodiment, a method of creating a medical device according to the present invention comprises: providing a first solvent in a container; introducing a salt or an acid of a radioactive isotope into the first solvent; introducing a second solvent into the first solution so as to form a second solution; and introducing the medical device into the second solution, wherein the ionic components of the radioactive isotope migrate into the molecular structure of the medical device. In another aspect, a method of creating a medical device that inhibits a hyperplastic response in biological tissue comprises placing a salt or an acid of a radioactive isotope in a fluid and permitting the salt or acid to disassociate in solution, submersing the sponge in the solution and permitting the radioactive isotopes to become trapped in the structure of the sponge.

公开(公告)号：US5707389A

公开(公告)日：1998-01-13

申请号：US486038

申请日：1995-06-07

Applicant: Frank Louw ,  Stephen A. Sosnowski ,  David Rosenthal

Inventor： Frank Louw ,  Stephen A. Sosnowski ,  David Rosenthal

IPC: A61B17/12 ,  A61B29/00

CPC classification number: A61B17/12022 ,  A61B17/12109 ,  A61B17/1214 ,  A61B2017/22097 ,  A61M2025/018

Abstract: The device for blocking (e.g., embolizing) the side branches of an anatomical passageway under endoscopic guidance. The device comprises an elongate catheter body having a side branch blocking apparatus, such as an embolization catheter, disposed therein and further incorporating an endoscope (e.g., an angioscope). The incorporated endoscope is useable to A) visually locate side branches which emanate from the anatomical passageway and b) visually observe the operation of the side branch blocking apparatus. Also disclosed are methods for utilizing a device of the forgoing character, including methods for performing in situ embolization of the side branches of a vein, under angioscopic visualization. The endoscopic component of the device may also be utilized to visually observe the use and/or effect of one or more separate device, such as valvulotome(s) used for cutting venous valves located within the lumen of a vein.

Abstract translation: 用于在内窥镜引导下阻塞（例如，栓塞）解剖通道的侧分支的装置。 该装置包括细长导管体，其具有设置在其中并进一步结合内窥镜（例如，血管造影仪）的侧分支阻塞装置，例如栓塞导管。 所配置的内窥镜可用于A）可视地定位从解剖通道发出的侧分支，以及b）目视观察侧支阻断装置的操作。 还公开了用于利用前述特征的装置的方法，包括在血管视觉可视化下进行静脉侧枝的原位栓塞的方法。 该装置的内窥镜部件也可以用于目视观察一个或多个分离装置（例如用于切割位于静脉内腔内的静脉瓣）的瓣膜切开的使用和/或效果。

公开(公告)号：US4047059A

公开(公告)日：1977-09-06

申请号：US689267

申请日：1976-05-24

Applicant: Bruce David Rosenthal

Inventor： Bruce David Rosenthal

IPC: H03K5/24 ,  H03K5/20

CPC classification number: H03K5/2472

Abstract: A switch, connected in series with a current source across a source of operating voltage, is opened and closed in accordance with the ratio of two input signals to produce an output signal. The current source conducts an output current directly or inversely proportional to the sum of the input signals whereby a parameter of the switched output signal, such as slew rate, is proportional to a parameter of the input signals, such as common mode voltage.

Abstract translation: 根据两个输入信号的比率，将一个与工作电压源的电流源串联连接的开关根据两个输入信号的比率被打开和关闭以产生输出信号。 电流源与输入信号的和直接或反比例地输出输出电流，从而开关输出信号（例如压摆率）的参数与诸如共模电压的输入信号的参数成正比。

公开(公告)号：US4039862A

公开(公告)日：1977-08-02

申请号：US649972

申请日：1976-01-19

Applicant: Andrew Gordon Francis Dingwall ,  Bruce David Rosenthal

Inventor： Andrew Gordon Francis Dingwall ,  Bruce David Rosenthal

IPC: H03K3/356 ,  H03K5/02 ,  H03K19/0185 ,  H03K17/60 ,  H03K3/286 ,  H03K3/353 ,  H03K17/04

CPC classification number: H03K19/018521 ,  H03K3/356104 ,  H03K5/023

Abstract: Each one of two switching transistors, driven by complementary input signals, has its conduction path connected between a different one of two output terminals and a first point of potential. Connected between each output terminal and a second point of potential are the conduction paths of a load transistor responsive to the signal at the other output terminal, and an input signal responsive transistor. When the switching transistor connected to one output terminal is being turned on, the effective impedance of the input signal responsive transistor connected between that output and the second point of potential is increased, thereby increasing the speed of response of the circuit and minimizing its power dissipation.

公开(公告)号：US4027148A

公开(公告)日：1977-05-31

申请号：US612045

申请日：1975-09-10

Applicant: Lawrence David Rosenthal

Inventor： Lawrence David Rosenthal

IPC: G09G1/08 ,  G06F15/34 ,  G06F3/14

CPC classification number: G09G1/08

Abstract: A vector generator having a digital input and a cathode ray tube (CRT) display output is disclosed. Digital values specifying the initial point of the line segment in Cartesian coordinates are converted to proportional voltages applied across the capacitors of two identical resistance-capacitance networks which control the positioning of the CRT beam. A second pair of digital values defining the length and direction of the line segment with respect to the initial point are normalized digitally by left shifts until the larger of the pair equals or exceeds a normalization constant. The normalized values are added to the initial point coordinates, and the sums are then converted to proportional voltages applied to the resistors of the two networks. Simultaneously, a timer preset during the normalization operation is started and the CRT beam is turned on to start the drawing of the line segment. As a result of the normalization, the voltages applied to the RC networks are larger than needed to draw the segment. Consequently, the beam will be turned off by the timer well before the outputs of the RC networks reach the applied voltages. Thus, line segments of widely differing lengths are drawn at a normalized fast rate and are displayed at a normalized uniform visual intensity on the CRT.

Abstract translation: 公开了一种具有数字输入和阴极射线管（CRT）显示输出的矢量发生器。 指定笛卡尔坐标中线段的初始点的数字值被转换为施加在两个相同电阻 - 电容网络的电容器上的比例电压，这两个电阻 - 电容网络控制CRT光束的定位。 定义相对于初始点的线段的长度和方向的第二对数字值通过左移进行数字归一化，直到该对中的较大者等于或超过归一化常数。 归一化值被添加到初始点坐标，然后将这些和转换成施加到两个网络的电阻器的比例电压。 同时，在归一化操作期间预设的定时器开始并且CRT光束被接通以开始绘制线段。 作为归一化的结果，施加到RC网络的电压大于绘制段所需的电压。 因此，在RC网络的输出达到施加的电压之前，光束将被定时器关闭。 因此，长度不同的线段以归一化的快速绘制，并以CRT上的归一化均匀视觉强度显示。