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公开(公告)号：US20080021495A1
公开(公告)日：2008-01-24
申请号：US11828921
申请日：2007-07-26
Applicant: Jeong Lee , Edwin Wang , Roseminda White , Jose Romero
Inventor： Jeong Lee , Edwin Wang , Roseminda White , Jose Romero
IPC: A61M29/00
CPC classification number: A61F2/95 , A61B2090/3954 , A61L29/106 , A61L29/126 , A61L29/18 , A61M25/10 , A61M25/1029 , A61M25/104 , A61M2025/1031 , A61M2025/1075 , A61M2025/1079
Abstract: Medical devices or components thereof, and particularly intracorporeal devices for therapeutic or diagnostic uses, which are formed at least in part of a polymeric material and a ferromagnetic or paramagnetic material, so that the medical device or component thereof is visible on magnetic resonance imaging (MRI) scans. In one embodiment, the medical device is a balloon catheter having an MRI visible balloon. In a presently preferred embodiment, there is an insufficient amount of the ferromagnetic or paramagnetic material within a wall of the balloon or coated onto a wall of the balloon to make the balloon radiopaque.
Abstract translation: 医疗器械或其组件，特别是用于治疗或诊断用途的体内器件，其至少部分地由聚合物材料和铁磁性或顺磁性材料形成，使得医疗器械或其组件在磁共振成像（MRI） ）扫描。 在一个实施例中，医疗装置是具有MRI可见气囊的气囊导管。 在目前优选的实施方案中，在球囊的壁内存在不足量的铁磁性或顺磁性材料，或涂覆在气球的壁上，以使气球不透射线。
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公开(公告)号：US07147619B2
公开(公告)日：2006-12-12
申请号：US10200274
申请日：2002-07-22
Applicant: Florencia Lim , Jeong S. Lee , Edwin Wang
Inventor： Florencia Lim , Jeong S. Lee , Edwin Wang
IPC: A61M29/02
CPC classification number: A61M25/104 , A61L29/06 , A61L29/085 , A61M2025/1075 , C08L79/02 , C08L75/04
Abstract: A balloon catheter and a method of making a balloon catheter, having a balloon with a first layer and a second layer, the first layer having at least one impregnated section impregnated with a polymeric material compatible with a polymeric material forming the catheter shaft. At least a portion of the impregnated section is fusion bonded to the shaft. In a presently preferred embodiment, the impregnated section is adjacent to a section of the first layer which is not impregnated with the compatible polymeric material. The impregnated section provides improved bonding of the balloon to the catheter shaft while minimizing the effect of the bond on catheter performance characteristics such as profile and flexibility.
Abstract translation: 气囊导管和制造球囊导管的方法，具有具有第一层和第二层的气囊，所述第一层具有浸渍有与形成导管轴的聚合物材料相容的聚合材料的至少一个浸渍部分。 浸渍部分的至少一部分熔合在轴上。 在目前优选的实施方案中，浸渍的部分邻近第一层的不被相容的聚合物材料浸渍的部分。 浸渍部分提供了球囊与导管轴的改善的粘合，同时最小化粘合对导管性能特征如轮廓和柔性的影响。
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公开(公告)号：US20050240214A1
公开(公告)日：2005-10-27
申请号：US11172543
申请日：2005-06-29
Applicant: Edwin Wang , Roseminda White , Jeong Lee , Tim Kitchen
Inventor： Edwin Wang , Roseminda White , Jeong Lee , Tim Kitchen
CPC classification number: A61M25/0069 , A61M25/001 , A61M25/10 , A61M2025/1093
Abstract: An elongated balloon catheter having a distal tip member on the distal end of the catheter and having a sleeve surrounding and secured at least to the proximal end of the distal tip member.
Abstract translation: 一种细长的气囊导管，其具有在导管的远端上的远侧末端构件，并且具有围绕并固定至远侧末端构件的近端的套筒。
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公开(公告)号：US20050240213A1
公开(公告)日：2005-10-27
申请号：US11038971
申请日：2005-01-18
Applicant: Jeong Lee , Edwin Wang , Roseminda White
Inventor： Jeong Lee , Edwin Wang , Roseminda White
CPC classification number: A61M25/0045 , A61L29/085 , A61M25/0009 , A61M25/104 , C08L77/12 , C08L75/04 , C08L79/08
Abstract: A catheter having an multilayered shaft section with a first layer formed of a polyimide first material and a second layer formed of a second material. In a presently preferred embodiment, the polyimide material is a thermoset polyimide. However, in alternative embodiments, a thermoplastic polyimide is used. The thermoset polyimide has a very high glass transition temperature (Tg) of approximately 400° C. (as measured by differential scanning calorimetry), and excellent dimensional stability at the processing temperature of polyamides commonly used in catheter components. As a result, during formation and assembly of the catheter, production of a thin polyimide layer with controlled dimensions is facilitated. The polyimide has a high modulus and provides a thin walled yet highly pushable shaft section, while the second layer provides kink resistance. In one embodiment, the second material is selected from the group consisting of a polyamide material and a polyurethane material.
Abstract translation: 一种具有多层轴部的导管，其具有由聚酰亚胺第一材料形成的第一层和由第二材料形成的第二层。 在目前优选的实施方案中，聚酰亚胺材料是热固性聚酰亚胺。 然而，在替代实施例中，使用热塑性聚酰亚胺。 热固性聚酰亚胺具有约400℃的非常高的玻璃化转变温度（Tg）（通过差示扫描量热法测量），以及在导管组件中常用的聚酰胺的加工温度下的优异的尺寸稳定性。 结果，在导管的形成和组装过程中，有助于生产具有受控尺寸的薄聚酰亚胺层。 聚酰亚胺具有高模量并且提供薄壁且高度可推动的轴部分，而第二层提供扭结阻力。 在一个实施方案中，第二材料选自聚酰胺材料和聚氨酯材料。
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公开(公告)号：US06520934B1
公开(公告)日：2003-02-18
申请号：US09474668
申请日：1999-12-29
Applicant: Jeong S. Lee , Vidya Nayak , John Schreiner , Christine Gutting , Edwin Wang , Gary Heinemann , Roseminda White
Inventor： Jeong S. Lee , Vidya Nayak , John Schreiner , Christine Gutting , Edwin Wang , Gary Heinemann , Roseminda White
IPC: A61M2900
CPC classification number: A61M25/0108 , A61M2025/1079
Abstract: A catheter assembly comprising a shaft and at least one flexible radiopaque marker affixed with the shaft. Flexibility of radiopaque marker is achieved by using a segmented band of radiopaque material or a coiled band formed by winding a wire or hollow tube filled with radiopaque material. The flexible radiopaque marker may be affixed with the shaft by an adhesive, by swaging, by crimping, by soldering, or by spring-action tension fit against the shaft.
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Patent Agency Ranking
公开(公告)号：US5376110A
公开(公告)日：1994-12-27
申请号：US74018
申请日：1993-06-09
Applicant: Roger Tu , Edwin Wang , Chris Kuo , Cary Hata
Inventor： Roger Tu , Edwin Wang , Chris Kuo , Cary Hata
CPC classification number: A61L27/24 , A61F2/062 , A61F2310/00365 , Y10S128/08 , Y10S623/921
Abstract: Preparing chemically cross-linked collagenous biological graft material by preparation processes which include the step of altering the locations and/or orientations of chemical cross-linkages formed during the collagen cross-linking process. Embodiments of the method include various processes whereby physical force, stress or movement is applied to alter the relative positioning of the collagen fibers within the graft materials during at least the initial period of exposure to the collagen cross-linking reagent.
Abstract translation: 通过制备方法制备化学交联的胶原生物移植材料，其包括改变在胶原交联过程中形成的化学交联的位置和/或取向的步骤。 该方法的实施例包括各种过程，其中施加物理力，应力或运动以在至少暴露于胶原交联试剂的初始阶段期间改变胶原纤维在移植材料内的相对定位。
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公开(公告)号：US07981244B2
公开(公告)日：2011-07-19
申请号：US11585071
申请日：2006-10-23
Applicant: Florencia Lim , Jeong S Lee , Edwin Wang
Inventor： Florencia Lim , Jeong S Lee , Edwin Wang
CPC classification number: A61M25/104 , A61L29/06 , A61L29/085 , A61M2025/1075 , C08L79/02 , C08L75/04
Abstract: A balloon catheter and a method of making a balloon catheter, having a balloon with a first layer and a second layer, the first layer having at least one impregnated section impregnated with a polymeric material compatible with a polymeric material forming the catheter shaft. At least a portion of the impregnated section is fusion bonded to the shaft. In a presently preferred embodiment, the impregnated section is adjacent to a section of the first layer which is not impregnated with the compatible polymeric material. The impregnated section provides improved bonding of the balloon to the catheter shaft while minimizing the effect of the bond on catheter performance characteristics such as profile and flexibility.
Abstract translation: 气囊导管和制造球囊导管的方法，具有具有第一层和第二层的气囊，所述第一层具有浸渍有与形成导管轴的聚合物材料相容的聚合材料的至少一个浸渍部分。 浸渍部分的至少一部分熔合在轴上。 在目前优选的实施方案中，浸渍的部分邻近第一层的不被相容的聚合物材料浸渍的部分。 浸渍部分提供了球囊与导管轴的改善的粘合，同时最小化粘合对导管性能特征如轮廓和柔性的影响。
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公开(公告)号：US20090147804A1
公开(公告)日：2009-06-11
申请号：US10582528
申请日：2005-12-08
Applicant: Edwin Wang , Brett Wang , Young Guo
Inventor： Edwin Wang , Brett Wang , Young Guo
IPC: H04L12/56
Abstract: Machine-readable media, methods, and apparatus are described. In some embodiments, a header policy for a packet to be transmitted through the network is defined based upon characteristics of the network and a header of the packet is compressed based upon whether the header policy indicates the header of the packet is to be compressed.
Abstract translation: 描述了机器可读介质，方法和装置。 在一些实施例中，基于网络的特性来定义要通过网络发送的分组的报头策略，并且基于报头策略是否要对分组的报头进行压缩来压缩分组的报头。
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39.发明申请公开(公告)号：US20070118076A1
公开(公告)日：2007-05-24
申请号：US11642294
申请日：2006-12-20
Applicant: Florencia Lim , Edwin Wang
Inventor： Florencia Lim , Edwin Wang
IPC: A61M29/00
CPC classification number: A61M25/1029 , A61M25/1034 , A61M2025/1075
Abstract: A method of making a catheter balloon, and a balloon catheter formed thereby, in which a layer of a catheter balloon is formed by providing a tubular member to serve as a non porous liner for cooperation with a polymeric tube, and enlarging radially a central or working section of the tubular member such that a first end of the tubular member is smaller in the radial direction with respect to the working section. The tubular member may also have a thickness at the working section that is less than a thickness of the first and second end portions. The first end section of the tubular member is bonded to a catheter shaft having a first outer diameter to form at least a portion of a skirt section of the balloon, and the second end section is bonded to the catheter shaft having a second outer diameter to form a portion of a skirt section, where the skirt sections have an improved high rupture pressure.
Abstract translation: 一种制造导管球囊的方法和由此形成的气囊导管，其中通过提供用于与聚合物管配合的无孔衬垫的管状构件形成导管球囊层，并且径向扩大中心或 所述管状构件的工作部分使得所述管状构件的第一端相对于所述工作部在径向方向上较小。 管状构件还可以具有在工作部分处的厚度小于第一和第二端部的厚度。 管状构件的第一端部结合到具有第一外径的导管轴，以形成气囊的裙部的至少一部分，并且第二端部接合到具有第二外径的导管轴 形成裙部的一部分，其中裙部具有改善的高破裂压力。
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公开(公告)号：US20060106366A1
公开(公告)日：2006-05-18
申请号：US10992873
申请日：2004-11-18
Applicant: Edwin Wang
Inventor： Edwin Wang
IPC: A61M31/00
CPC classification number: A61K31/11 , A61B17/22 , A61K31/336 , A61K31/352 , A61K31/729
Abstract: A method including introducing a treatment device via a transluminal route within a blood vessel to a treatment site including a vulnerable plaque; and dispensing a treatment agent including a compound having a property that tends to modify a property of a content of the vulnerable plaque. A kit including a first treatment agent including a property capable of modifying a property of a content of a vulnerable plaque; and a different second treatment agent. A composition including a treatment agent capable of modifying the mobility of a content of a vulnerable plaque in a form and concentration suitable for dispensing through a catheter into a blood vessel.
Abstract translation: 一种方法，包括通过血管内的经腔途径将治疗装置引入包括易损斑块的治疗部位; 并且分配包括具有倾向于改变易损斑块含量的性质的性质的化合物的处理剂。 一种试剂盒，其包括第一处理剂，其包括能够改变脆性斑块含量的性质的性质; 和不同的第二处理剂。 一种组合物，其包含能够以适于通过导管分配到血管中的形式和浓度的脆性斑块的内容物的迁移率来改变的处理剂。
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