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公开(公告)号:US07147619B2
公开(公告)日:2006-12-12
申请号:US10200274
申请日:2002-07-22
申请人: Florencia Lim , Jeong S. Lee , Edwin Wang
发明人: Florencia Lim , Jeong S. Lee , Edwin Wang
IPC分类号: A61M29/02
CPC分类号: A61M25/104 , A61L29/06 , A61L29/085 , A61M2025/1075 , C08L79/02 , C08L75/04
摘要: A balloon catheter and a method of making a balloon catheter, having a balloon with a first layer and a second layer, the first layer having at least one impregnated section impregnated with a polymeric material compatible with a polymeric material forming the catheter shaft. At least a portion of the impregnated section is fusion bonded to the shaft. In a presently preferred embodiment, the impregnated section is adjacent to a section of the first layer which is not impregnated with the compatible polymeric material. The impregnated section provides improved bonding of the balloon to the catheter shaft while minimizing the effect of the bond on catheter performance characteristics such as profile and flexibility.
摘要翻译: 气囊导管和制造球囊导管的方法,具有具有第一层和第二层的气囊,所述第一层具有浸渍有与形成导管轴的聚合物材料相容的聚合材料的至少一个浸渍部分。 浸渍部分的至少一部分熔合在轴上。 在目前优选的实施方案中,浸渍的部分邻近第一层的不被相容的聚合物材料浸渍的部分。 浸渍部分提供了球囊与导管轴的改善的粘合,同时最小化粘合对导管性能特征如轮廓和柔性的影响。
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公开(公告)号:US06946173B2
公开(公告)日:2005-09-20
申请号:US10103274
申请日:2002-03-21
申请人: Florencia Lim , Chi Le Long , Charles D. Claude , Jeong S. Lee , Srinivasan Sridharan , Fernando Gonzalez , Edwin Wang
发明人: Florencia Lim , Chi Le Long , Charles D. Claude , Jeong S. Lee , Srinivasan Sridharan , Fernando Gonzalez , Edwin Wang
IPC分类号: A61L29/00 , A61F2/958 , A61L29/04 , A61L29/08 , A61L29/12 , A61M25/00 , A61M25/16 , B32B1/08 , A61M25/10 , A61M29/00
CPC分类号: A61M25/1034 , A61L29/041 , A61L29/085 , A61L29/126 , A61M25/1006 , A61M25/1025 , A61M25/1029 , A61M2025/1075 , Y10T428/13 , Y10T428/1334 , Y10T428/1352 , Y10T428/1376 , Y10T428/1386 , Y10T428/139 , Y10T428/1393 , C08L27/18
摘要: A catheter balloon formed of a polymeric material such as expanded polytetrafluoroethylene (ePTFE) bonded to a second layer formed of a low tensile set polymer and/or impregnated with a low tensile set polymer. In a presently preferred embodiment, the low tensile set polymer is a silicone-polyurethane copolymer elastomer or a diene polymer elastomer. The low tensile set polymer has high strength, low modulus, high elongation, and low tensile set. The diene or silicone-polyurethane has a low tensile set, which facilitates deflation of the balloon to a low profile deflated configuration. One aspect of the invention provides improved attachment of the diene to the ePTFE. In one embodiment, the second layer is formed of a diene mixed with a bonding promoter such as a vulcanizing agent which is covalently bonded to the diene.
摘要翻译: 由诸如膨胀聚四氟乙烯(ePTFE)的聚合物材料形成的导管球囊结合到由低拉伸凝固聚合物形成的第二层和/或用低拉伸固化聚合物浸渍。 在目前优选的实施方案中,低拉伸固化聚合物是硅氧烷 - 聚氨酯共聚物弹性体或二烯聚合物弹性体。 低强度聚合物具有高强度,低模量,高伸长率和低拉伸强度。 二烯或硅氧烷聚氨酯具有低拉伸组合,其有利于将气囊放气至低剖面放气构型。 本发明的一个方面提供了改进的二烯与ePTFE的连接。 在一个实施方案中,第二层由与二烯混合的二烯混合形成,所述二烯与粘合促进剂例如硫化剂混合。
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公开(公告)号:US06287314B1
公开(公告)日:2001-09-11
申请号:US09063969
申请日:1998-04-21
申请人: Jeong S. Lee , Florencia Lim
发明人: Jeong S. Lee , Florencia Lim
IPC分类号: A61M2900
CPC分类号: A61L29/049 , A61F2/958 , A61M25/1027 , A61M25/1029 , A61M25/104 , A61M29/02 , B29C47/00 , B29C47/0019 , B29C47/0023 , B29C47/0033 , B29C47/065 , B29C55/24 , B29K2075/00 , B29L2022/022 , B29L2031/7542
摘要: An intravascular catheter system for properly implanting a stent in a body lumen generally comprising a catheter having an elongated shaft with an inflatable balloon formed of compliant material and a stent mounted on the working length of the balloon. The balloon material is compliant within the working range of the balloon to provide substantial radial expansion. The wingless radially expansive balloon expands in a uniform manner, thereby producing uniform expansion and implantation of the stent.
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公开(公告)号:US06319259B1
公开(公告)日:2001-11-20
申请号:US09357697
申请日:1999-07-20
申请人: Jeong S. Lee , Florencia Lim
发明人: Jeong S. Lee , Florencia Lim
IPC分类号: A61F1100
CPC分类号: A61L29/049 , A61F2/958 , A61M25/1027 , A61M25/1029 , A61M25/104 , A61M29/02 , B29C47/00 , B29C47/0019 , B29C47/0023 , B29C47/0033 , B29C47/065 , B29C55/24 , B29K2075/00 , B29L2022/022 , B29L2031/7542
摘要: An intravascular catheter system for properly implanting a stent in a body lumen generally comprising a catheter having an elongated shaft with an inflatable balloon formed of compliant material and a stent mounted on the working length of the balloon. The balloon material is compliant within the working range of the balloon to provide substantial radial expansion. The wingless radially expansive balloon expands in a uniform manner, thereby producing uniform expansion and implantation of the stent.
摘要翻译: 一种用于将支架适当地植入体腔内的血管内导管系统,其通常包括具有细长轴的导管,所述导管具有由顺应性材料形成的可膨胀气囊和安装在所述气囊的工作长度上的支架。 球囊材料在气球的工作范围内是柔顺的,以提供显着的径向膨胀。 无翼状径向膨胀气囊以均匀的方式膨胀,从而产生支架的均匀膨胀和植入。
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公开(公告)号:US07532920B1
公开(公告)日:2009-05-12
申请号:US09872216
申请日:2001-05-31
申请人: Robert D. Ainsworth , Deborah Kilpatrick , Jeong S. Lee , Bridget A. Hurley , Jeffrey T. Ellis , Marc Jalisi , Florencia Lim , Chi Long
发明人: Robert D. Ainsworth , Deborah Kilpatrick , Jeong S. Lee , Bridget A. Hurley , Jeffrey T. Ellis , Marc Jalisi , Florencia Lim , Chi Long
CPC分类号: A61B5/02055 , A61B5/02007 , A61B5/02028 , A61B5/6851
摘要: Apparatus and method to perform therapeutic treatment and diagnosis of a patient's vasculature through the use of an intravascular device having an optical fiber disposed therein. In an embodiment of this invention, the apparatus includes a therapeutic guidewire and at least one optical fiber disposed through the therapeutic guidewire, the optical fiber capable of providing diagnostic information before, during, and after the therapeutic treatment. In an embodiment, diagnostic information includes vessel and blood characteristics such as hemodynamic characteristics, hematological parameters related to blood and blood components, and thermal parameters of the vasculature.
摘要翻译: 通过使用其中设置有光纤的血管内装置来对患者的脉管系统进行治疗处理和诊断的装置和方法。 在本发明的一个实施例中,该设备包括治疗导丝和通过治疗导丝设置的至少一根光纤,所述光纤能够在治疗前后,治疗期间和之后提供诊断信息。 在一个实施方案中,诊断信息包括血管和血液特征,例如血液动力学特征,与血液和血液成分有关的血液学参数,以及脉管系统的热参数。
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公开(公告)号:US06527741B1
公开(公告)日:2003-03-04
申请号:US09469966
申请日:1999-12-21
申请人: Jeong S. Lee , Florencia Lim , Cheryl Stiger , Carolyn Voyles , Vincent Bavaro
发明人: Jeong S. Lee , Florencia Lim , Cheryl Stiger , Carolyn Voyles , Vincent Bavaro
IPC分类号: A61M2900
CPC分类号: B29C49/00 , A61M25/1027 , A61M2025/1031 , A61M2025/1059 , B29C43/10 , B29C43/36 , B29C55/28 , B29K2105/258 , B29L2022/025 , B29L2031/7542
摘要: A resizable inflatable balloon, primarily for use with balloon catheters. The resizable inflatable balloon comprises a first portion and an adjacent second portion. The first portion is inflatable to a working diameter at a first pressure while the second portion does not substantially expand at the first pressure. The second portion does expand to the working diameter at a second pressure greater than the first pressure, so that subsequent inflation at the first pressure inflates the first portion and the second portion to the working diameter. The methods of resizing the inflatable members include placing the inflatable balloon in a mold and supplying inflation fluid to expand the second member to the working diameter. In practice, a catheter having the resizable inflatable balloon is guided through a patient's vasculature until the inflatable balloon is positioned in a desired region. Inflation fluid is supplied at the first pressure to inflate the first portion to the working diameter. The catheter is withdraw and the inflatable balloon is resized as described above. The catheter is reintroduced to the patient's vasculature and inflation fluid is then supplied at the first pressure to inflate both the first and second portions.
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公开(公告)号:US09855400B2
公开(公告)日:2018-01-02
申请号:US12477695
申请日:2009-06-03
申请人: Jeong S. Lee , Edwin Wang , Roseminda J. White
发明人: Jeong S. Lee , Edwin Wang , Roseminda J. White
CPC分类号: A61M25/0045 , A61L29/085 , A61M25/0009 , A61M25/104 , C08L77/12 , C08L75/04 , C08L79/08
摘要: A catheter having an multilayered shaft section with a first layer formed of a polyimide first material and a second layer formed of a second material. In a presently preferred embodiment, the polyimide material is a thermoset polyimide. However, in alternative embodiments, a thermoplastic polyimide is used. The thermoset polyimide has a very high glass transition temperature (Tg) of approximately 400° C. (as measured by differential scanning calorimetry), and excellent dimensional stability at the processing temperature of polyamides commonly used in catheter components. As a result, during formation and assembly of the catheter, production of a thin polyimide layer with controlled dimensions is facilitated. The polyimide has a high modulus and provides a thin walled yet highly pushable shaft section, while the second layer provides kink resistance. In one embodiment, the second material is selected from the group consisting of a polyamide material and a polyurethane material.
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公开(公告)号:US08221444B2
公开(公告)日:2012-07-17
申请号:US12271726
申请日:2008-11-14
申请人: Edwin Wang , Roseminda J. White , Jeong S. Lee , Tim Kitchen
发明人: Edwin Wang , Roseminda J. White , Jeong S. Lee , Tim Kitchen
IPC分类号: A61M29/00
CPC分类号: A61M25/0069 , A61M25/001 , A61M25/10 , A61M2025/1093
摘要: An elongated balloon catheter having a distal tip member on the distal end of the catheter and having a sleeve surrounding and secured at least to the proximal end of the distal tip member.
摘要翻译: 一种细长的气囊导管,其具有在导管的远端上的远侧末端构件,并且具有围绕并固定至远侧末端构件的近端的套筒。
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公开(公告)号:US06979342B2
公开(公告)日:2005-12-27
申请号:US09957593
申请日:2001-09-19
申请人: Jeong S. Lee , Edwin Wang
发明人: Jeong S. Lee , Edwin Wang
CPC分类号: A61M25/10 , A61L29/085 , A61L2420/08 , A61M25/001 , A61M25/0045 , A61M25/0069 , A61M2025/1093 , C08L79/08 , C08L77/00 , C08L77/12 , C08L75/04
摘要: A catheter having an elongated shaft which has a multilayered distal tip with a first layer formed of a polyimide first material and a second layer formed of a polymeric second material. In one embodiment the multilayered distal tip is a separate member, distal to the distal end of a proximal portion of the shaft. In another embodiment, the shaft has an outer tubular member, and a multilayered inner tubular member with a distal end which forms the multilayered distal tip of the shaft. In a presently preferred embodiment, the polyimide material is a thermoset polyimide. In one embodiment, the polymeric second material is a polyamide material.
摘要翻译: 一种具有细长轴的导管,该细长轴具有由聚酰亚胺第一材料形成的第一层和由聚合物第二材料形成的第二层的多层远端。 在一个实施例中,多层远侧末端是远离轴的近端部分的远端的分离的构件。 在另一个实施例中,轴具有外部管状构件和多层内部管状构件,其具有形成轴的多层远侧末端的远端。 在目前优选的实施方案中,聚酰亚胺材料是热固性聚酰亚胺。 在一个实施方案中,聚合物第二材料是聚酰胺材料。
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公开(公告)号:US06911017B2
公开(公告)日:2005-06-28
申请号:US09957354
申请日:2001-09-19
申请人: Jeong S. Lee , Edwin Wang , Roseminda J. White , Jose A. Romero
发明人: Jeong S. Lee , Edwin Wang , Roseminda J. White , Jose A. Romero
CPC分类号: A61F2/95 , A61B2090/3954 , A61L29/106 , A61L29/126 , A61L29/18 , A61M25/10 , A61M25/1029 , A61M25/104 , A61M2025/1031 , A61M2025/1075 , A61M2025/1079
摘要: Medical devices or components thereof, and particularly intracorporeal devices for therapeutic or diagnostic uses, which are formed at least in part of a polymeric material and a ferromagnetic or paramagnetic material, so that the medical device or component thereof is visible on magnetic resonance imaging (MRI) scans. In one embodiment, the medical device is a balloon catheter having an MRI visible balloon. In a presently preferred embodiment, there is an insufficient amount of the ferromagnetic or paramagnetic material within a wall of the balloon or coated onto a wall of the balloon to make the balloon radiopaque.
摘要翻译: 医疗器械或其组件,特别是用于治疗或诊断用途的体内器件,其至少部分地由聚合物材料和铁磁性或顺磁性材料形成,使得医疗器械或其组件在磁共振成像(MRI) )扫描。 在一个实施例中,医疗装置是具有MRI可见气囊的气囊导管。 在目前优选的实施方案中,在球囊的壁内存在不足量的铁磁性或顺磁性材料,或涂覆在气球的壁上,以使气球不透射线。
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