公开(公告)号：US20100316618A1

公开(公告)日：2010-12-16

申请号：US12745006

申请日：2008-11-27

申请人： Hiroshi Tsuboi ,  Noriko Kaneko ,  Akina Satou ,  Akinori Kume ,  katsunori Kimura

发明人： Hiroshi Tsuboi ,  Noriko Kaneko ,  Akina Satou ,  Akinori Kume ,  katsunori Kimura

IPC分类号： A61K35/74 ,  C12N1/20 ,  C12P1/04 ,  A61P7/00

CPC分类号： C12R1/225 ,  A23C9/1234 ,  A23L33/135 ,  A23Y2220/37 ,  A61K35/747

摘要： The present invention provides lactic acid bacteria which are suitable for use for dietary products and pharmaceuticals, and which can suppress the increase of blood uric acid level.Various types of lactic acid bacteria were cultured in the presence of a purine, the amount of the purine consumed and the amount of purine degradation products produced were measured, and several lactic acid bacteria showing remarkable purine-decomposing ability were selected. Lactic acid bacteria that were assessed to have high purine-decomposing ability according to the above-mentioned selection were orally administered to rats reared on purine-containing feed, the general status and serum uric acid level of the rats were measured, and the effect of lactic acid bacteria administration on serum uric acid levels was examined. As a result, lactic acid bacteria that significantly suppress the increase of serum uric acid levels, Lactobacillus gasseri OLL2922, were found.

摘要翻译： 本发明提供适用于饮食品和药物的乳酸菌，可抑制血液中尿酸水平的升高。 在嘌呤存在下培养各种类型的乳酸菌，测定嘌呤消耗量和产生的嘌呤降解产物量，选择显示出显着的嘌呤分解能力的几种乳酸菌。 对含有嘌呤的饲料饲养的大鼠口服给予根据上述选择被评估为具有高嘌呤分解能力的乳酸菌，测定大鼠的一般状态和血清尿酸水平， 检测乳酸菌对血清尿酸水平的影响。 结果发现，显着抑制血清尿酸水平升高的乳酸菌，加氏乳杆菌（Lactobacillus gasseri）OLL2922。

公开(公告)号：US6113378A

公开(公告)日：2000-09-05

申请号：US862703

申请日：1997-05-23

申请人： Hiroshi Tsuboi ,  Toshinori Okamoto ,  Kunio Kojima

发明人： Hiroshi Tsuboi ,  Toshinori Okamoto ,  Kunio Kojima

IPC分类号： B30B11/02 ,  B30B11/04 ,  B29C43/02

CPC分类号： B30B11/04 ,  B30B11/027

摘要： A mold for molding a drum shaped magnetic core having two flanges connected by a coil winding core portion. The mold includes a die defining a cylindrical cavity having an inner diameter substantially equal to an outer diameter of the flanges. A pair of die inserts are movable in an orthogonal direction relative to the cylindrical cavity and define a diameter of the coil winding core portion of the drum shaped magnetic core. The diameter of the coil winding core portion is smaller than the outer diameter of the flanges. An upper punch and a lower punch are inserted into the cylindrical cavity from a corresponding end opening of the mold such that each forms a flange. A central punch is disposed coaxially within one of the punches to form the coil winding core portion.

摘要翻译： 一种用于模制鼓形磁芯的模具，其具有通过线圈绕组芯部分连接的两个凸缘。 模具包括限定具有基本上等于凸缘的外径的内径的圆柱形腔的模具。 一对模插件可以相对于圆柱形空腔在正交方向上移动，并且限定鼓形磁芯的线圈绕组芯部分的直径。 线圈绕芯部分的直径小于凸缘的外径。 上冲头和下冲头从模具的对应的端部开口插入到圆柱形腔中，使得每个形成凸缘。 中心冲头同轴地布置在一个冲头内以形成线圈卷绕芯部分。

公开(公告)号：US5625911A

公开(公告)日：1997-05-06

申请号：US537760

申请日：1996-01-19

申请人： Chiaki Nakayama ,  Kuniaki Shinohara ,  Naoki Sato ,  Hiroshi Tsuboi

发明人： Chiaki Nakayama ,  Kuniaki Shinohara ,  Naoki Sato ,  Hiroshi Tsuboi

IPC分类号： A47K13/00 ,  A61B10/00 ,  E03D9/00 ,  G01N1/10 ,  G01N33/483 ,  G01N33/493 ,  E03D11/00 ,  A61B5/00

CPC分类号： G01N33/493 ,  A61B10/007

摘要： A method and an apparatus (30) for sampling urine at a toilet (10) equipped with a standard water closet bowl fixture (12). An elongated, curved, urine sampling trough (32) having a U-shaped cross-section is used. For sampling of urine, the sampling trough (32) is positioned in the vertical central plane (46) of the toilet bowl fixture in such a manner that it extends obliquely between the upper front region and the bottom region of the inner space of the bowl (14). As the urine sampling trough (32) covers a substantial length in the vertical direction as well as in the fore-and-aft direction, the urine column hits on the sampling trough even when the trajectory of urine column is fluctuated in the vertical or fore-and-aft direction, whereby urine is effectively sampled. As the urine sampling trough is elongated and curved, it can be readily stored under the toilet seat when not in use.

摘要翻译： PCT No.PCT / JP95 / 00259 Sec。 371日期1996年1月19日 102（e）日期1996年1月19日PCT提交1995年2月23日PCT公布。 公开号WO95 / 23337 日期1995年8月31日一种用于在配备有标准洗手间碗具（12）的马桶（10）上抽尿的方法和装置（30）。 使用具有U形横截面的细长弯曲的尿液采样槽（32）。 为了取样尿液，采样槽（32）以这样的方式定位在马桶装置的垂直中心平面（46）中，使其在碗的内部空间的上部前部区域和底部区域之间倾斜地延伸 （14）。 当尿液采样槽（32）在垂直方向和前后方向上覆盖相当长的长度时，即使当尿液柱的轨迹在垂直或前方波动时，尿液塔也会在取样槽上撞击 后方向，从而有效地抽取尿液。 当尿液采样槽细长且弯曲时，可以在不使用时容易地储存在马桶座下。

公开(公告)号：US5184359A

公开(公告)日：1993-02-09

申请号：US748211

申请日：1991-08-22

申请人： Naoki Tsukamura ,  Kiyoshi Alyfuku ,  Yuzuru Nakamura ,  Yoshiki Hiruta ,  Hiroshi Tsuboi

发明人： Naoki Tsukamura ,  Kiyoshi Alyfuku ,  Yuzuru Nakamura ,  Yoshiki Hiruta ,  Hiroshi Tsuboi

IPC分类号： A61B5/022 ,  A61B10/00

CPC分类号： A61B5/02241 ,  A61B10/0051 ,  A61B10/007

摘要： A toilet system (10) with urine assay function is disclosed which comprises a toilet stool (12) having a toilet bowl (14) and a small urine-sampling cavity (52). A frame (42) is mounted on the toilet stool to support a testing sheet handling and transfer mechanism (30) which comprises a swingable carriage (46) and a slidable arm (50) supported by the carriage for linear telescoping movement. The carriage is swingable about a vertical axis (48) between a first position in which the carriage is oriented toward the sampling cavity and a second position in which the carriage is oriented to a lateral side of the stool wherein a disposal station is provided.The toilet system enables the use of testing sheets (32) which are made from water insoluble materials.Various other embodiments are also disclosed.The system provides a high degree of reliability of analysis.