公开(公告)号：US20120308539A1

公开(公告)日：2012-12-06

申请号：US13544756

申请日：2012-07-09

申请人： Hiroshi Tsuboi ,  Noriko Kaneko ,  Akina Satou ,  Yoshinobu Tsuchiya

发明人： Hiroshi Tsuboi ,  Noriko Kaneko ,  Akina Satou ,  Yoshinobu Tsuchiya

IPC分类号： C12N1/20 ,  A61P1/00 ,  A61K35/74

CPC分类号： A23C9/1234 ,  A23C9/1238 ,  A23L33/135 ,  A23V2002/00 ,  A23Y2220/61 ,  A61K35/747 ,  C12R1/225 ,  A23V2200/30

摘要： Various types of lactic acid bacteria were cultured in the presence of a purine, the amount of the purine consumed and the amount of purine degradation products produced were measured, and several lactic acid bacteria showing remarkable purine-decomposing ability were selected. Lactic acid bacteria that were assessed to have high purine-decomposing ability according to the above-mentioned selection were orally administered to rats reared on purine-containing feed, the general status and serum uric acid level of the rats were measured, and the effect of lactic acid bacteria administration on serum uric acid levels was examined. As a result, lactic acid bacteria that significantly suppress the increase of serum uric acid levels, Lactobacillus gasseri OLL2959 and Lactobacillus oris OLL2779, were found.

摘要翻译： 在嘌呤存在下培养各种类型的乳酸菌，测定嘌呤消耗量和产生的嘌呤降解产物量，选择显示出显着的嘌呤分解能力的几种乳酸菌。 对含有嘌呤的饲料饲养的大鼠口服给予根据上述选择被评估为具有高嘌呤分解能力的乳酸菌，测定大鼠的一般状态和血清尿酸水平， 检测乳酸菌对血清尿酸水平的影响。 结果发现显着抑制血清尿酸水平升高的乳酸菌，加氏乳杆菌OLL2959和乳酸杆菌OLL2779。

公开(公告)号：US08171578B2

公开(公告)日：2012-05-08

申请号：US12182990

申请日：2008-07-30

申请人： Masami Tsujita ,  Tomoyuki Abe ,  Naoki Kabe ,  Hiroshi Tsuboi ,  Masayuki Nagaishi ,  Katsuhisa Tsuchiya ,  Shoichi Tsuiki ,  Kensuke Murata

发明人： Masami Tsujita ,  Tomoyuki Abe ,  Naoki Kabe ,  Hiroshi Tsuboi ,  Masayuki Nagaishi ,  Katsuhisa Tsuchiya ,  Shoichi Tsuiki ,  Kensuke Murata

IPC分类号： E03C1/05

CPC分类号： E03C1/057 ,  G01S13/56 ,  G01S13/582 ,  G01S13/88

摘要： There is provided a water discharge system. A water discharge system includes a water discharge portion; a sensor unit which acquires movement information about an object based on a radiated electric wave, and outputs a detecting signal; and a control unit which controls water discharge of the water discharge portion based on the detecting signal. When it is detected that the object is decelerated to a first threshold velocity or less, the control unit controls the water discharge portion to start the water discharge.

摘要翻译： 提供排水系统。 排水系统包括排水部分; 传感器单元，其基于辐射电波获取关于对象的移动信息，并输出检测信号; 以及控制单元，其基于检测信号来控制排水部的排水。 当检测到物体减速到第一阈值速度或更小时，控制单元控制排水部分开始排水。

公开(公告)号：US20090070922A1

公开(公告)日：2009-03-19

申请号：US12172176

申请日：2008-07-11

申请人： Kensuke MURATA ,  Masayuki NAGAISHI ,  Tomoyuki ABE ,  Hiroshi TSUBOI

发明人： Kensuke MURATA ,  Masayuki NAGAISHI ,  Tomoyuki ABE ,  Hiroshi TSUBOI

IPC分类号： E03D13/00

CPC分类号： G01V3/12 ,  E03D5/105 ,  E03D13/00

摘要： A urinal includes: a urinal body; a high-frequency sensor which radiates a radio beam obliquely passing through an upper surface of the urinal body toward a bowl and receives a reflected wave from an object so as to generate a detection signal; and a valve which discharges or stops flushing water to the urinal body in response to the detection signal. An angle formed between a first plane including the upper surface of the urinal body and a second plane including a radiation surface of an antenna of the high-frequency sensor is in a range of more than 0 degree to less than 90 degree. A cross line where the first plane and the second plane intersect with each other is substantially parallel to a horizontal direction of the urinal body. The radio beam is a linearly-polarized wave. An excitation direction of the radio beam intersects with the cross line. An intensity of the radio beam passing through the urinal body is larger than that of the radio beam reflected by the upper surface.

摘要翻译： 小便池包括：小便器; 高频传感器，其将倾斜地通过小便器的上表面的无线电束朝向碗体辐射，并从物体接收反射波，以产生检测信号; 以及响应于检测信号而将冲洗水排出或停止到小便器体的阀。 在包括小便器的上表面的第一平面和包括高频传感器的天线的辐射表面的第二平面之间形成的角度在大于0度至小于90度的范围内。 第一平面和第二平面彼此交叉的交叉线基本上平行于小便器的水平方向。 无线电波束是线性偏振波。 无线电波束的激发方向与交叉线相交。 通过小便器的无线电波的强度大于由上表面反射的无线电波束的强度。

公开(公告)号：US20080088510A1

公开(公告)日：2008-04-17

申请号：US11664292

申请日：2005-09-29

申请人： Kensuke Murata ,  Hiroshi Tsuboi ,  Kengo Iwata ,  Tomoyuki Abe

发明人： Kensuke Murata ,  Hiroshi Tsuboi ,  Kengo Iwata ,  Tomoyuki Abe

IPC分类号： H01Q3/00 ,  H01Q9/04

CPC分类号： H01Q3/24 ,  H01Q9/0407 ,  H01Q9/0442 ,  H01Q19/005 ,  H01Q19/28

摘要： A microstrip antenna has feed element 102 and parasitic elements 104, 106 on the front surface of substrate 1. Microwave electrical power is applied to feed element 102. Parasitic elements 104, 106 are connected via through hole type leads passing through substrate 1, to switches upon the rear surface of substrate 1, respectively. By actuating the switches individually, parasitic elements 104, 106 are individually switched between a grounded state and a float state. The direction of the radio beam emitted from the microstrip antenna is varied by selecting which of parasitic elements 104, 106 is grounded and floated. A microwave signal source connects to feed element 102 via an feed line 108 very much shorter than the wavelength, accordingly the transmission losses being low and the efficiency being excellent.

摘要翻译： 微带天线具有馈电元件102和衬底1的前表面上的寄生元件104,106。 微波电力施加到馈电元件102。 寄生元件104,106通过穿过衬底1的通孔型引线分别连接到衬底1的后表面上。 通过单独地驱动开关，寄生元件104,106在接地状态和浮置状态之间单独切换。 通过选择寄生元件104,106中的哪一个接地并漂浮来改变从微带天线发射的无线电波束的方向。 微波信号源通过比波长短得多的馈线108连接到馈电元件102，因此传输损耗低，效率优异。

公开(公告)号：US20080036662A1

公开(公告)日：2008-02-14

申请号：US10593392

申请日：2005-03-23

申请人： Kengo Iwata ,  Hiroshi Tsuboi ,  Kensuke Murata ,  Toshio Koguro ,  Youichi Murase

发明人： Kengo Iwata ,  Hiroshi Tsuboi ,  Kensuke Murata ,  Toshio Koguro ,  Youichi Murase

IPC分类号： H01Q1/38

CPC分类号： H01Q9/0407 ,  H01Q9/0421 ,  H01Q9/0442 ,  H01Q21/065

摘要： A plurality of antenna electrodes 11, 12, 13, 14 on a substrate 1 can be connected to a ground electrode on the substrate 1 via connectors at spots 11A-11C, 12A-12C, 13A-13C, and 14A-14C. Each connector can be opened/closed by a switch; or provided with a impedance varying device. Any one of the antenna electrodes may be connected to the ground electrode by the switch or the impedance varying device. The radio wave beam outputted from this antenna electrode shifts in phase from the radio wave beams outputted from the other antenna electrodes, whereby the direction of the integrated radio wave beam is inclined. Connecting one or another of the spots 11A-11C, 12A-12C, 13A-13C, and 14A-14C to the ground electrode changes the direction and the magnitude of the integrated radio wave beam.

摘要翻译： 基板1上的多个天线电极11,12,13,14可以通过11-11C，12A-12C，13A-13C的连接器连接到基板1上的接地电极，并且 14 A- 14 C.每个连接器都可以由开关打开/关闭; 或设置有阻抗变化装置。 天线电极中的任何一个可以通过开关或阻抗变化装置连接到接地电极。 从该天线电极输出的无线电波从与其他天线电极输出的无线电波相位移位，由此集成无线电波束的方向倾斜。 将一个或另一个点11A-11C，12A-12C，13A-13C和14A-14C连接到接地电极改变了集成无线电波束的方向和大小。

公开(公告)号：US06589659B1

公开(公告)日：2003-07-08

申请号：US09533951

申请日：2000-03-23

申请人： Shigeo Imai ,  Hiroshi Tsuboi

发明人： Shigeo Imai ,  Hiroshi Tsuboi

IPC分类号： B32B904

CPC分类号： C08J7/047 ,  C08J7/04 ,  C08J2323/06 ,  C08J2483/00 ,  D06N3/128 ,  Y10T428/31663 ,  Y10T428/31667

摘要： There is disclosed a sheet coated with a first silicone compound having a certain surface tension and a second silicone compound having a lower surface tension than the first silicone compound so that only the second silicone compound appears on the sheet surface or the second silicone compound appears on the sheet surface more than the first silicone compound. The sheet thus coated with the silicone compounds are highly water-repellent and highly effective in preventing adhesion of protein-containing stains. Moreover, it is highly resistant to friction so that the above effects can be maintained for a long period of time.

摘要翻译： 公开了涂覆有具有一定表面张力的第一硅氧烷化合物的片材和具有比第一硅氧烷化合物低的表面张力的第二硅氧烷化合物，使得仅第二硅氧烷化合物仅出现在片材表面上或第二有机硅化合物出现在 片材表面多于第一种硅氧烷化合物。 由此涂覆有硅氧烷化合物的片材具有高度的疏水性，并且在防止含蛋白质污渍的粘附方面非常有效。 此外，它对摩擦具有高度的耐受性，从而可以长期保持上述效果。

公开(公告)号：US6115853A

公开(公告)日：2000-09-12

申请号：US214355

申请日：1998-12-31

申请人： Shinji Shibata ,  Takeshi Takaki ,  Yumiko Kataoka ,  Kiyoshi Fujino ,  Takenori Fukushima ,  Shingo Tanaka ,  Hiroshi Tsuboi ,  Hidetaka Miyahara

发明人： Shinji Shibata ,  Takeshi Takaki ,  Yumiko Kataoka ,  Kiyoshi Fujino ,  Takenori Fukushima ,  Shingo Tanaka ,  Hiroshi Tsuboi ,  Hidetaka Miyahara

IPC分类号： E03D11/02 ,  E03D11/08

CPC分类号： E03D11/08 ,  E03D11/02

摘要： When a cleaning button for cleaning the toilet bowl is operated, by a manner as pressing, a switching valve 41 switches the flushing water supply destination to a position for cleaning the bowl part. The flushing water is then jetted out of a spout nozzle 35 disposed inside a Z water conduit 161 as a jet flow. The jet flow from the spout nozzle 35 causes water inside the Z water conduit 161 and water inside the flushing water reservoir 104 to flow through the Z water conduit 161 and to be spouted toward an inlet 121 of a waste trap 102, like a jet flow spouted by a jet pump. This supplies a heavy flow of flushing water amplified in the volume into the waste trap 102 all at once to flush out the filth in the bowl part 101.

摘要翻译： PCT No.PCT / JP97 / 02724 Sec。 371 1998年12月31日第 102（e）日期1998年12月31日PCT提交1997年8月5日PCT公布。 出版物WO98 / 05829 日期1998年2月12日当用于清洁马桶的清洁按钮被操作时，通过按压的方式，切换阀41将冲洗水供应目的地切换到用于清洁碗部的位置。 然后将冲洗水从作为喷流的Z水导管161内的喷口35喷出。 来自喷口35的射流使得Z水导管161内的水和冲洗水储存器104内的水流过Z水导管161，并且朝向废液捕集器102的入口121喷射，如喷射流 由喷射泵喷出。 这样一来，将体积中放大的大量冲洗水一次提供到废液收集器102中，以冲洗碗部101中的污物。

公开(公告)号：US20110236360A1

公开(公告)日：2011-09-29

申请号：US13119382

申请日：2009-09-29

申请人： Daisuke Ochi ,  Hiroshi Tsuboi

发明人： Daisuke Ochi ,  Hiroshi Tsuboi

IPC分类号： A61K35/74 ,  C12N1/20 ,  C12P1/04 ,  A61P19/10 ,  A61P7/06 ,  A61P13/12

CPC分类号： A61K35/74 ,  A23L33/135 ,  A23V2002/00 ,  A23Y2220/37 ,  C12R1/225 ,  A23V2200/306

摘要： The present invention provides lactic acid bacteria having oxalic acid-degrading activity several times higher than those of conventionally known lactic acid bacteria having an oxalic acid-degrading activity, and uses thereof. Lactic acid bacteria capable of degrading a large amount of oxalic acid were screened from 132 strains of Lactobacillus lactic acid bacteria that have been independently isolated from feces and gastric juices of human adults. As a result, lactic acid bacteria having an oxalic acid degradation rate of 50% or more when cultured at 37° C. for 72 hours in a culture medium containing 10 mM oxalic acid at pH 6.5 at the start of culture were discovered.

摘要翻译： 本发明提供了具有比常规已知的具有草酸降解活性的乳酸菌高几倍的草酸降解活性的乳酸菌及其用途。 从132个来自人类粪便和胃液中独立分离的乳酸杆菌乳杆菌筛选能够降解大量草酸的乳酸菌。 结果发现，培养开始时，在含有10mM草酸的培养基中，在37℃培养72小时，草酸降解率为50％以上的乳酸菌。

公开(公告)号：US20080146657A1

公开(公告)日：2008-06-19

申请号：US10578015

申请日：2004-11-04

申请人： Hiroshi Tsuboi ,  Shuji Ikegami ,  Tomonori Kamiyama ,  Zai-si Ji ,  Yukio Asami ,  Hiroyuki Itou ,  Munehiro Oda ,  Kazuo Shin

发明人： Hiroshi Tsuboi ,  Shuji Ikegami ,  Tomonori Kamiyama ,  Zai-si Ji ,  Yukio Asami ,  Hiroyuki Itou ,  Munehiro Oda ,  Kazuo Shin

IPC分类号： A61K31/352 ,  A61P3/04 ,  A61P3/10 ,  C07D311/30

CPC分类号： A61K31/7048 ,  A23L33/105 ,  A61K31/352 ,  A61K36/62 ,  C07D311/30

摘要： The present inventors produced lotus leaf extracts, and discovered that quercetin is one of the active ingredients. As a result of treating β3-adrenergic receptor-expressing cells and feeding diabetes model mice with quercetin and evaluating its effects, the present inventors discovered specifically that quercetin produces obesity-improving effects and antidiabetic effects by acting as a β3-adrenergic receptor agonist.

摘要翻译： 本发明人发明了莲叶提取物，发现槲皮素是活性成分之一。 作为治疗β3 - 肾上腺素能受体表达细胞并用槲皮素喂养糖尿病模型小鼠并评价其效果的结果，本发明人特别发现槲皮素通过作为 β3 - 肾上腺素能受体激动剂。

公开(公告)号：US20070036872A1

公开(公告)日：2007-02-15

申请号：US10577612

申请日：2004-11-04

申请人： Hiroshi Tsuboi ,  Shuji Ikegami ,  Zai-si Ji ,  Hiroyuki Itou ,  Munehiro Oda ,  Kazuo Shin

发明人： Hiroshi Tsuboi ,  Shuji Ikegami ,  Zai-si Ji ,  Hiroyuki Itou ,  Munehiro Oda ,  Kazuo Shin

IPC分类号： A61K36/185

CPC分类号： A61K36/65 ,  A23L33/105 ,  A23V2002/00 ,  A23V2200/328

摘要： The present inventors focused on the lotus plant and prepared lotus extracts. When α-glucosidase and its substrate sucrose were reacted with the lotus extracts to examine the effect of adding the extracts on the enzymatic reaction, the lotus extracts were found to have α-glucosidase inhibitory activity. Furthermore, when the lotus extract and sucrose were administered to mice and their blood glucose levels were measured, the lotus extracts were found to suppress blood glucose levels. More specifically, the present inventors discovered that the lotus extracts have α-glucosidase inhibitory activity and can be used to control blood glucose levels.

摘要翻译： 本发明人专注于莲花植物和制备的莲花提取物。 当α-葡萄糖苷酶及其底物蔗糖与莲花提取物反应以检查添加提取物对酶反应的作用时，发现莲藕提取物具有α-葡糖苷酶抑制活性。 此外，当向小鼠施用荷叶提取物和蔗糖并测量其血糖水平时，发现莲藕提取物抑制血糖水平。 更具体地，本发明人发现莲藕提取物具有α-葡糖苷酶抑制活性，可用于控制血糖水平。