公开(公告)号：US20070220986A1

公开(公告)日：2007-09-27

申请号：US11384817

申请日：2006-03-21

Applicant: Leif Smith ,  Sauli Tulkki

Inventor： Leif Smith ,  Sauli Tulkki

IPC: G01L9/06

CPC classification number: G01L9/0025 ,  B60C23/0408 ,  G01L9/008

Abstract: A sensor and insertion assembly 2 is used for intravascular measurement of pressure in a living body. The assembly includes a sensor chip 6 having a substrate body 8 with a recess covered by a pressure sensitive film 10 thereby forming a cavity 12. A piezoelectric element, preferably in the form of a piezoelectric film 14, is arranged in connection with the pressure sensitive film, and energy is applied to the piezoelectric element such that acoustic waves are generated in the element. The piezoelectric element is arranged to generate an output signal, representing the pressure at the film, in dependence on the measured properties of the acoustic waves related to the deflection of the pressure sensitive film.

Abstract translation: 传感器和插入组件2用于血管内测量活体内的压力。 组件包括传感器芯片6，传感器芯片6具有衬底本体8，衬底本体8具有被压敏薄膜10覆盖的凹部，从而形成空腔12.压电元件优选为压电薄膜14，与压力敏感 膜和能量被施加到压电元件，使得在该元件中产生声波。 压电元件被布置成根据与压敏膜的偏转相关的声波的测量特性，产生表示膜上的压力的输出信号。

公开(公告)号：US06623418B2

公开(公告)日：2003-09-23

申请号：US09851430

申请日：2001-05-09

Applicant: Leif Smith

Inventor： Leif Smith

IPC: A61N500

CPC classification number: A61N5/1001 ,  H01J35/32 ,  H01J2235/164

Abstract: A miniaturized radiation device, having a support member in the form of a flexible sheet, and a circuit pattern of electrical contact pads and interconnecting conductor lines or leads provided on said support member. The pads are interconnected via said patterned lines. There is also a plurality of radiation chips electrically connected to selected ones of said pads. Preferably the device is wrapped around a core member, that may be a wire, such that the assembly is suitable for the insertion into a living body for the controlled administration of radiation at a therapy location.

公开(公告)号：US06241651B1

公开(公告)日：2001-06-05

申请号：US09379782

申请日：1999-08-24

Applicant: Leif Smith ,  Carolina Ribbing

Inventor： Leif Smith ,  Carolina Ribbing

IPC: A61N500

CPC classification number: A61N5/1001 ,  H01J35/32

Abstract: A method and apparatus of creating a miniaturized source of radiation and delivering radiation to a location such as a therapy location. The radiation source includes a member made of a material emitting electrons when energy is supplied to the member. There is an electron retarding member disposed opposite the electron emitting member, and the electron retarding member is made of a material emitting ionizing radiation when electrons are retarded therein. The radiation source is further provided on an elongated member in a distal region thereof, and the elongated member is insertable into the body.

Abstract translation: 一种创建微型辐射源并将辐射传送到诸如治疗位置的位置的方法和装置。 辐射源包括当能量被供应到构件时由发射电子的材料制成的构件。 存在与电子发射部件相对设置的电子延迟部件，并且当电子被延迟时，电子阻挡部件由发射电离辐射的材料制成。 辐射源还设置在其远端区域中的细长构件上，并且细长构件可插入体内。

公开(公告)号：US06167763A

公开(公告)日：2001-01-02

申请号：US09547733

申请日：2000-04-12

Applicant: Lars Tenerz ,  Ola Hammarström ,  Leif Smith

Inventor： Lars Tenerz ,  Ola Hammarström ,  Leif Smith

IPC: G01L700

CPC classification number: G01L19/142 ,  A61B5/0215 ,  A61B5/6851 ,  A61M25/09 ,  A61M2025/0002 ,  A61M2025/09175 ,  G01L19/147

Abstract: The invention relates to a sensor/guide wire device for biological pressure measurements having a guide wire (16, 17, 18, 21, 23) having a distal and a proximal end, and a pressure sensor device (19) mounted at the distal end of the guide wire. The distal portion can be a solid wire member (16) surrounded by a spiral member (18), and the sensor (19) can be an electrical sensor of a piezoresistive type. The sensor (19) is mounted on the solid wire (16). The sensor is mounted in a cantilevering fashion such that a pressure sensitive end of the sensor does not contact any structure other than its mount. This prevents forces (bending artifacts) from being exerted on the sensor, which could otherwise interfere with pressure measurements.

Abstract translation: 本发明涉及一种用于生物压力测量的传感器/导丝装置，其具有具有远端和近端的导丝（16,17,18,21,23）和安装在远端的压力传感器装置（19） 的导丝。 远侧部分可以是由螺旋构件（18）包围的实心线构件（16），并且传感器（19）可以是压阻型的电传感器。 传感器（19）安装在实心线（16）上。 传感器以悬臂方式安装，使得传感器的压力敏感端不接触除了其安装件之外的任何结构。 这防止了力（弯曲伪影）施加在传感器上，否则可能会干扰压力测量。

公开(公告)号：US20130231871A1

公开(公告)日：2013-09-05

申请号：US13884359

申请日：2011-10-06

Applicant: Bertil Hok ,  Lars Tenerz ,  Leif Smith ,  Annika Kaisdotter Andersson

Inventor： Bertil Hok ,  Lars Tenerz ,  Leif Smith ,  Annika Kaisdotter Andersson

IPC: G01N33/497

CPC classification number: G01N33/497 ,  A61B5/0836 ,  A61B5/087 ,  A61B5/4845 ,  A61B5/6885 ,  G01N21/031 ,  G01N21/3504 ,  G01N33/4972

Abstract: A multifunctional breath analyzer includes a receptor unit for receiving a breath sample from a test subject, a sensing unit providing a signal corresponding to the concentration of at least one volatile substance within the sample, elements for providing a signal indicative of the dilution of the breath sample, and an analyzing unit/processing unit for the identification and quantification of the volatile substance of the breath sample. The signal processing unit is configured to perform at least two different calculations for the quantification, and the signal processing unit is also configured to automatically display the result of a selected calculation, the selection being based on the signal indicating dilution.

Abstract translation: 多功能呼吸分析仪包括用于从测试对象接收呼吸样本的受体单元，提供对应于样品内的至少一种挥发性物质的浓度的信号的感测单元，用于提供指示呼吸稀释的信号的元件 样品和分析单元/处理单元，用于鉴定和定量呼吸样品的挥发性物质。 所述信号处理单元被配置为对所述量化执行至少两个不同的计算，并且所述信号处理单元还被配置为自动显示所选计算的结果，所述选择基于指示稀释度的信号。

公开(公告)号：US20120271178A1

公开(公告)日：2012-10-25

申请号：US13534653

申请日：2012-06-27

Applicant: Leif SMITH

Inventor： Leif SMITH

IPC: A61B5/0215

CPC classification number: A61B5/0215 ,  A61B5/6851

Abstract: A pressure sensor wire assembly measures pressure inside a body of a patient. The assembly comprises a pressure sensor element for measuring pressure and to generate a pressure sensor signal representative of the pressure, and a pressure sensor wire having the pressure sensor element at its distal portion, and adapted to be inserted into the body in order to position the sensor element within the body. A sensor signal adapting circuitry is an integrated part of the assembly, wherein the pressure sensor signal is applied to the adapting circuitry which is adapted to automatically generate an output pressure signal, related to the sensor signal, in a standardized format such that the measured pressure is retrievable by an external physiology monitor. The assembly further comprises an external pressure sensor to measure the pressure outside the patient's body and to generate external pressure values in dependence thereto.

Abstract translation: 压力传感器线组件测量患者体内的压力。 组件包括用于测量压力并产生代表压力的压力传感器信号的压力传感器元件，以及压力传感器线，其压力传感器元件在其远端部分处，并且适于插入到主体中，以便将 传感器元件在体内。 传感器信号适配电路是组件的集成部分，其中压力传感器信号被施加到适配电路，其适于以标准化格式自动产生与传感器信号相关的输出压力信号，使得测量的压力 可通过外部生理学监测器检索。 组件还包括外部压力传感器，用于测量患者身体外部的压力并根据其产生外部压力值。

公开(公告)号：US20100268038A1

公开(公告)日：2010-10-21

申请号：US12742025

申请日：2008-08-22

Applicant: Leif Smith

Inventor： Leif Smith

IPC: A61B5/00

CPC classification number: A61B5/0215 ,  A61B5/0002 ,  A61B5/6851 ,  A61B2560/0214 ,  A61B2560/0443 ,  A61B2562/225 ,  A61M25/09 ,  H01R13/622 ,  H01R13/6683 ,  H01R13/6691 ,  H01R24/66 ,  H01R24/76 ,  H01R2103/00

Abstract: A transmitter unit with an attachable energy source is provided for a sensor guidewire. The transmitter unit is adapted to be connected to a proximal end of a sensor guidewire provided, at its distal end, with a sensor to measure a physiological parameter inside a patient. In some embodiments, the transmitter unit is adapted to wirelessly communicate by a communication signal with a communication unit, arranged in connection with an external device, in order to transfer measured physiological data to the external device. The attachable energy source can be a battery pack or battery holder provided with connecting electrical connecting surfaces. Preferably, the connection is protected from penetrating fluids by a protective seal.

Abstract translation: 为传感器导丝提供具有可附接能量的发射器单元。 发射器单元适于连接到传感器导丝的近端，传感器导丝在其远端处设置有用于测量患者体内生理参数的传感器。 在一些实施例中，发射机单元适于通过通信信号与通信单元进行无线通信，该通信单元与外部设备结合地布置，以将测量的生理数据传送到外部设备。 可附接能源可以是具有连接电连接表面的电池组或电池座。 优选地，通过保护性密封来保护连接不渗透流体。

公开(公告)号：US20100222661A1

公开(公告)日：2010-09-02

申请号：US12739326

申请日：2008-10-24

Applicant: Pär Von Malmborg ,  Leif Smith

Inventor： Pär Von Malmborg ,  Leif Smith

IPC: A61B5/04

CPC classification number: A61B5/0215 ,  A61M25/09 ,  A61M2025/09108 ,  A61M2025/09133

Abstract: There is a sensor guide wire (1) for intravascular measurements of physiological variables in a living body. The sensor guide wire (1) comprises at least two elongate sections, a first tubular elongate section (2) being tubular in the longitudinal direction of the sensor guide wire (1), and a second elongate section (3) that is adapted to be inserted a predetermined distance (5) into said first tubular section (2), a sensor element (10) provided in the distal part of said sensor guide wire (1), for measuring the physiological variable and to generate a sensor signal in response to said variable, at least one signal transmitting cable connected to the sensor element (10) to transmit sensor signals to a male connector provided in the proximal part of said sensor guide wire (1). The tubular section (2) is provided with at least one through-going opening (4) in a direction perpendicular to the longitudinal direction of the guide wire (1) and positioned a second predetermined distance (6) from one end of the tubular section (2), wherein the guide wire (1) comprises a locking member (7) to be fitted into the opening (4) in order to join the sections (2, 3) together when the second elongate section (3) is inserted into the tubular section (2).

Abstract translation: 传感器导丝（1）用于生物体内生理变量的血管内测量。 传感器导丝（1）包括至少两个细长部分，沿着传感器导丝（1）的纵向方向管状的第一管状细长部分（2）和适于成为 将预定距离（5）插入所述第一管状部分（2）中，设置在所述传感器导丝（1）的远端部分中的传感器元件（10），用于测量生理变量并响应于 所述变量，连接到所述传感器元件（10）的至少一个信号传输电缆将传感器信号发送到设置在所述传感器导丝（1）的近端部分中的公连接器。 管状部分（2）在垂直于导丝（1）的纵向方向的方向上设置有至少一个贯穿开口（4），并且从管状部分的一端定位第二预定距离（6） （2），其中所述导丝（1）包括锁定构件（7），以在所述第二细长部分（3）插入时将所述锁定构件（7）装配到所述开口（4）中，以便将所述部分（2,3） 管状部分（2）。

公开(公告)号：US20080132806A1

公开(公告)日：2008-06-05

申请号：US11607120

申请日：2006-12-01

Applicant: Leif Smith

Inventor： Leif Smith

IPC: A61B5/00

CPC classification number: A61B5/036 ,  A61B5/6851 ,  A61M25/09033 ,  A61M2025/0002

Abstract: A sensor and guide wire assembly (21; 41; 61; 81) for intravascular measurements of a physiological variable in a living body includes a sensor element (22; 42; 62; 82) mounted at a distal sensor portion (23; 43; 63; 83) of a guide wire (24; 44; 64; 84), wherein the sensor portion exhibits a maximal cross-sectional dimension which is larger than a maximal cross-sectional dimension of guide wire portions (28, 30; 48, 50; 68, 70) located proximally of the sensor portion.

Abstract translation: 用于生物体内生理变量的血管内测量的传感器和导丝线组件（21; 41; 61; 81）包括安装在远端传感器部分（23; 43; 43）处的传感器元件（22; 42; 62; 导线（24; 44; 64; 84）的最大横截面尺寸大于导丝部分（28,30; 48; 84）的最大横截面尺寸， 50; 68,70）位于传感器部分的近侧。

公开(公告)号：US07331236B2

公开(公告)日：2008-02-19

申请号：US11384817

申请日：2006-03-21

Applicant: Leif Smith ,  Sauli Tulkki

Inventor： Leif Smith ,  Sauli Tulkki

IPC: G01L7/00

CPC classification number: G01L9/0025 ,  B60C23/0408 ,  G01L9/008

Abstract: A sensor and insertion assembly 2 is used for intravascular measurement of pressure in a living body. The assembly includes, a sensor chip 6 having a substrate body 8 with a recess covered by a pressure sensitive film 10 thereby forming a cavity 12. A piezoelectric element, preferably in the form of a piezoelectric film 14, is arranged in connection with the pressure sensitive film, and energy is applied to the piezoelectric element such that acoustic waves are generated in the element. The piezoelectric element is arranged to generate an output signal, representing the pressure at the film, in dependence on the measured properties of the acoustic waves related to the deflection of the pressure sensitive film.

Abstract translation: 传感器和插入组件2用于血管内测量活体内的压力。 组件包括传感器芯片6，传感器芯片6具有衬底本体8，衬底本体8具有由压敏膜10覆盖的凹部，从而形成空腔12。 优选以压电膜14的形式的压电元件与压敏膜连接设置，并且能量被施加到压电元件，使得在该元件中产生声波。 压电元件被布置成根据与压敏膜的偏转相关的声波的测量特性，产生表示膜上的压力的输出信号。