Abstract:
A metal artifact reduction (MAR) method and system for reducing metal artifacts from X-ray images. The method is suitable for CT images generated with metallic elements exterior to a patient being scanned, for example, where external probes are applied to a patient, such as ultrasound probes. The method may be embodied in a computer algorithm for use, for example, in radiotherapy treatment planning and patient positioning procedures. In one application, the disclosed technique improves the dose delivery accuracy in ultrasound-guided cardiac radioablation, making this treatment modality a viable option for cardiac arrhythmias.
Abstract:
The invention relates to methods for diagnosing the early stages of heart failure. The invention particularly relates to diagnosing class I and class II heart failure, based on the New York Heart Association (NYHA) classification system. The invention can also discriminate between healthy controls and heart failure patients in NYHA class III/IV.
Abstract:
The present invention provides compositions and methods for the pretreatment of lignocellulosic material. The present invention further provides for pretreated lignocellulosic material that can be used to produce useful products, such as fermentable sugars.
Abstract:
A method of forming a coating on a substrate is provided comprising forming a lignin solution by at least partially dissolving lignin in a solvent, coating the lignin solution onto the substrate and exposing the lignin coated substrate to a treatment selected from the group consisting of a heat treatment and an acid treatment. The coating provides for improved waterproofing and/or strengthening of the substrate.
Abstract:
The present invention provides compositions and methods for the pretreatment of lignocellulosic material. The present invention further provides for pretreated lignocellulosic material that can be used to produce products, such as fermentable sugars.
Abstract:
The present invention relates to improved protein-based biosensors that are suitable for detection of one or more target molecules in a sample. The biosensors are fully-reversible with dynamic ranges suitable for analytic and diagnostic applications. The biosensors of the present invention may be used in synthetic biology, for example in constructing artificial cellular or extracellular signalling networks.
Abstract:
This disclosure concerns compositions and methods for novel RNA inhibition molecules (e.g., small/short hairpin RNA (shRNA) molecules), polynucleotides encoding such molecules, use of such novel RNA inhibition molecules to inhibit a target gene by suppressing the expression of the mRNA of the target gene, and for application such as the of control insect pests, and transgenic plants that produce, and are protected, by these novel RNA inhibition molecules are described.
Abstract:
The present invention relates to combinations of a poly(2-oxazoline) or poly(2-oxazine)5 polymer or copolymer having an allylamido side chain and a cross-linker, cross-linked compositions thereby obtained and hydrogels thereof. Further, the present invention discloses methods of providing the combination, compositions and hydrogels described herein and their use.
Abstract:
The present disclosure relates to cancer and more particularly, methods of treating and/or determining the responsiveness to treatment and/or prognosis of cancers, such as lung cancer and breast cancer.
Abstract:
A fluorescent macromolecule comprising: a linear sequence-defined backbone; and a plurality of fluorophores attached to the backbone in a pre-determined order to form a fluorophore sequence, wherein the fluorophores in the fluorophore sequence are separated from one another by a distance permitting interaction between adjacent fluorophores such that the macromolecule emits fluorescence at a plurality of wavelengths when irradiated by light to form a fluorescence emission spectrum, and wherein the fluorescence emission spectrum has a profile that is determined by the fluorophore sequence.