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公开(公告)号:US20230232723A1
公开(公告)日:2023-07-20
申请号:US14328120
申请日:2014-07-10
Applicant: The University of Houston System
Inventor: Jarek Wosik , Jerzy Krupka , Venkat Selvamanickam
CPC classification number: G01R33/1246 , G01R33/007 , H10N60/203
Abstract: A method and apparatus for quality control of superconducting tapes, comprising non-destructive and non-contact methods for measuring the surface resistance of a superconducting tape during tape growth. The dielectric resonator techniques of the present invention can be adapted for measurements at the elevated temperatures used during annealing as well as at room and lower temperatures, providing the opportunity for real-time quality control of semiconductor tapes as they are being fabricated.
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32.
公开(公告)号:US20230149295A1
公开(公告)日:2023-05-18
申请号:US17906027
申请日:2021-03-09
Applicant: University of Houston System , The Board of Regents of The University of Texas System , Tract Pharmaceuticals, Inc.
Inventor: Frank McKEON , Rahul NEUPANE , Jingzhong XIE , Wa XIAN , Matthew VINCENT , Shan WANG
CPC classification number: A61K9/0024 , A61K47/34 , A61K45/06
Abstract: The present disclosure addresses IBD from the standpoint of inhibiting or ablating pathogenic mucosal stem cells cloned from defined regions of disease in the gastrointestinal tract. In the case of Crohn's disease, for example, isolation of those stem cells according to the methods of the present disclosure reveals a pattern of inflammatory gene expression in stem cells from the terminal ileum and colon that is epigenetically maintained despite months of continuous cultivation in the absence of immune or stromal cells, or of intestinal microbes. Superimposed on this distributed inflammatory phenotype is a differentiation defect that profoundly and specifically alters the mucosal barrier properties of the terminal ileum. The co-existence of diseased and normal stem cells within the same endoscopic biopsies of Crohn's disease patients implicates an epigenetically enforced heterogeneity among mucosal stem cells in the dynamics of this condition.
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公开(公告)号:US20230147307A1
公开(公告)日:2023-05-11
申请号:US17983005
申请日:2022-11-08
Applicant: University of Houston System
Inventor: Francisco Carlos Robles Hernández , Shelton Ray Taylor
IPC: B23K23/00
CPC classification number: B23K23/00
Abstract: Methods and systems for producing a thermite weld include applying a first vibration and a second vibration to molten thermite material within a mold between a first piece and a second piece to be welded. The first vibration includes a first vibration frequency and a first amplitude, and the second vibration includes a second vibration frequency and a second amplitude. The first vibration and the second vibration are applied simultaneously to the molten thermite material until the molten thermite material cools below a liquid-to-solid transition temperature. Interference patterns and harmonics between the first vibration and the second vibration enhance the elimination of gas voids within the molten thermite material and enhance grain refinement in the molten thermite material of the resulting thermite weld without damaging the mold.
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公开(公告)号:US20230124578A1
公开(公告)日:2023-04-20
申请号:US17889596
申请日:2022-08-17
Applicant: UNIVERSITY OF HOUSTON SYSTEM
Inventor: Monzer A. Hourani , Zhifeng Ren , Luo Yu
IPC: B01D46/42 , B01D46/52 , B01D39/16 , B01D46/00 , B01D46/44 , A61L9/16 , A61L9/014 , F24F8/108 , H05B1/02 , H05B3/12
Abstract: A detoxification device for removing pathogens from air within an environment. The detoxification device may include a filtration media for catching and retaining particles larger than about 0.3 micrometers (μm) with an efficiency of at least 99%. The detoxification device may also include a heating element having a metallic foam. The heating element may be heated upon application of an electrical current to the heating element. The heating element may, upon being heated, heat the filtration media to a target temperature that is effective to kill a pathogen.
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35.
公开(公告)号:US20230117728A1
公开(公告)日:2023-04-20
申请号:US17054551
申请日:2019-05-10
Applicant: University of Houston System
Inventor: Eva M. Harth , Dain B. Beezer , Anthony Keyes , Glen Richard Jones
IPC: C08F293/00
Abstract: A method of polymerizing a first, and a second class of monomers to form product polymer. The first class of monomers polymerize via a radical pathway in the presence of light, and the second class of monomers polymerize via an insertion pathway in the absence of light.
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36.
公开(公告)号:US20230053296A1
公开(公告)日:2023-02-16
申请号:US17973738
申请日:2022-10-26
Applicant: University of Houston System
Inventor: Yingchun Zhang , Nicholas Dias , Yang Liu , Henry Lai , Theresa M. Spitznagle , Christopher P. Smith
Abstract: A system for determining a treatment regimen for chronic pelvic pain (CPP) includes an electromyography (EMG) probe including electrodes. Each electrode detects pelvic floor muscle activity. An EMG sensor array includes bipolar EMG sensors configured to detect muscle activity of muscles associated with or supporting the pelvic floor muscles. An EMG amplifier is in communication with the EMG probe or the EMG sensor array. The EMG amplifier includes a plurality of input channels. Each input channel receives data of muscle activity in the pelvic floor muscles or the muscles associated with or supporting the pelvic floor muscles from the EMG probe or the EMG sensor array. A processor of a computer performs muscle network analysis using the data of muscle activity in the pelvic floor muscles or the muscles associated with or supporting the pelvic floor muscles. A treatment regimen for CPP is recommended based on the muscle network analysis.
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37.
公开(公告)号:US11553839B2
公开(公告)日:2023-01-17
申请号:US16228979
申请日:2018-12-21
Applicant: University of Houston System
Inventor: Kirill V. Larin , Manmohan Singh , Jiasong Li , Zhaolong Han , Michael D. Twa
Abstract: Provided herein are systems and methods to measure the intraocular pressure, ocular tissue geometry and the biomechanical properties of an ocular tissue, such as an eye-globe or cornea, in one instrument. The system is an optical coherence tomography subsystem and an applanation tonometer subsystem housed as one instrument and interfaced with a computer for at least data processing and image display. The system utilizes an air-puff and a focused micro air-pulse to induce deformation and applanation and displacement in the ocular tissue. Pressure profiles of the air puff with applanation times are utilized to measure intraocular pressure. Temporal profiles of displacement and/or spatio-temporal profiles of a displacement-generated elastic wave are analyzed to calculate biomechanical properties.
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38.
公开(公告)号:US20220395685A1
公开(公告)日:2022-12-15
申请号:US17838758
申请日:2022-06-13
Applicant: University of Houston System
Inventor: Yingchun Zhang
Abstract: A system for mapping neuromuscular junctions for botulinum neurotoxin (BoNT) injections includes a stimulation electrode and an electromyography (EMG) sensor array including EMG sensors configured to be arranged about a person's face. Each EMG sensor detects muscle activity of a facial muscle of a facial muscle group. An EMG amplifier includes a plurality of input channels. Each input channel receives data of facial muscle activity in the facial muscle group from the EMG sensor array. A computer is in communication with the EMG amplifier. A processor of the computer identifies neuromuscular junctions (NMJs) of the facial muscle group based on the data of facial muscle activity received from the EMG sensor array. The plurality of NMJs are mapped with respect to the at least one facial muscle group of the body of the person. At least one NMJ site for BoNT injection is recommended by the computer.
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39.
公开(公告)号:US20220386862A1
公开(公告)日:2022-12-08
申请号:US17882682
申请日:2022-08-08
Applicant: University of Houston System
Inventor: Kirill V. Larin , Achuth Nair , Manmohan Singh , Salavat Aglyamov
Abstract: A system and method for measuring biomechanical properties of tissues without external excitation are capable of measuring and quantifying these parameters of tissues in situ and in vivo. The system and method preferably utilize a phase-sensitive optical coherence tomography (OCT) system for measuring the displacement caused by the intrinsic heartbeat. The method allows noninvasive and nondestructive quantification of tissue mechanical properties. Preferably, the method is used to detect tissue stiffness and to evaluate its stiffness due to intrinsic pulsatile motion from the heartbeat. This noninvasive method can evaluate the biomechanical properties of the tissues in vivo for detecting the onset and progression of degenerative or other diseases and evaluating the efficacy of therapies.
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公开(公告)号:US20220367777A1
公开(公告)日:2022-11-17
申请号:US17836072
申请日:2022-06-09
Applicant: University of Houston System
Inventor: Zhifeng REN , Hangtian ZHU
Abstract: A method of thermoelectric power generation by converting heat to electricity via the use of a ZrCoBi-based thermoelectric material, wherein a thermoelectric conversion efficiency of the ZrCoBi-based thermoelectric material is greater than or equal to 7% at a temperature difference of up to 800 K.
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