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公开(公告)号:US20100247531A1
公开(公告)日:2010-09-30
申请号:US12731100
申请日:2010-03-24
申请人: Avi Ashkenazi , Jing Qing , Christian Wiesmann , Yan Wu
发明人: Avi Ashkenazi , Jing Qing , Christian Wiesmann , Yan Wu
IPC分类号: A61K39/395 , C07K16/00 , C07K16/22 , A61P35/00 , C07H21/04 , C12N15/63 , C12N1/00 , C12N5/00 , C12P21/00
CPC分类号: C07K16/2863 , A61K39/395 , A61K39/3955 , A61K39/39558 , A61K2039/505 , C07K16/3038 , C07K16/3061 , C07K2317/24 , C07K2317/34 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/732 , C07K2317/75 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2319/30
摘要: The invention provides FGFR3 antibodies, and compositions comprising and methods of using these antibodies.
摘要翻译: 本发明提供FGFR3抗体,以及组合物和使用这些抗体的方法。
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32.
公开(公告)号:US20100172921A1
公开(公告)日:2010-07-08
申请号:US12598537
申请日:2007-05-17
IPC分类号: A61K39/395 , A61P35/02 , A61P35/00 , A61P35/04 , C07K16/30
CPC分类号: C07K16/2863 , A61K2039/505 , C07K16/22 , C07K2317/21 , C07K2317/31 , C07K2317/622 , C07K2317/76 , C07K2317/92
摘要: The application provides Nrp2 antagonists, such as anti-Nrp2 antibodies, and their use in the prevention and treatment of tumor metastasis.
摘要翻译: 该应用提供Nrp2拮抗剂,例如抗Nrp2抗体,以及它们在预防和治疗肿瘤转移中的用途。
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公开(公告)号:US07720071B2
公开(公告)日:2010-05-18
申请号:US12042930
申请日:2008-03-05
申请人: Yan Wu , Song Bi , Timothy Bornemisza
发明人: Yan Wu , Song Bi , Timothy Bornemisza
CPC分类号: H04L12/5601 , H04L2012/5652
摘要: Disclosed are exemplary techniques for compressing ATM cells by substituting reduced headers for the original headers. A header table may be maintained at the transmitting end whereby headers are stored in table entries based on a table index generated from a hash function applied to the headers. A copy of the header table may be maintained at the receiving end and may be updated by populating idle cells with header table contents. Upon receipt of a reduced ATM cell at the receiving end, the reduced header may be replaced with a full header obtained from the copy of the header table maintained at the receiving end. The present invention further provides techniques for registration and management of hash collisions.
摘要翻译: 公开了用于通过用缩小的报头代替原始报头来压缩ATM信元的示例性技术。 可以在发送端维护头表,由此基于从应用于报头的散列函数生成的表索引,将报头存储在表条目中。 标题表的副本可以在接收端保持,并且可以通过用标题表内容填充空闲小区来更新。 在接收端接收到减少的ATM信元时,可以用从保持在接收端的报头表的副本获得的全标头替换减少的报头。 本发明还提供了用于哈希冲突的注册和管理的技术。
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公开(公告)号:US20100119516A1
公开(公告)日:2010-05-13
申请号:US12608034
申请日:2009-10-29
申请人: Yan Wu
发明人: Yan Wu
IPC分类号: A61K39/395 , C07K16/18
CPC分类号: C07K16/2863 , A61K39/39558 , A61K2039/505 , C07K2317/21 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92 , A61K2300/00
摘要: The present invention is directed to antibodies against human transforming growth factor beta receptor II (TGFβRII), pharmaceutical compositions comprising antibodies and methods of using the antibodies, alone or in combination, for example, for treating cancer and fibrosis.
摘要翻译: 本发明涉及针对人转化生长因子β受体II(TGF&bgr; RII)的抗体,包含抗体的药物组合物和单独或组合使用抗体的方法,例如用于治疗癌症和纤维化。
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公开(公告)号:US20100055103A1
公开(公告)日:2010-03-04
申请号:US12547728
申请日:2009-08-26
申请人: YONGMEI CHEN , YAN (HELEN) HU , WENJUN OUYANG , SCOTT STAWICKI , YAN WU
发明人: YONGMEI CHEN , YAN (HELEN) HU , WENJUN OUYANG , SCOTT STAWICKI , YAN WU
CPC分类号: C07K16/244 , C07K2317/31 , C07K2317/34 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/92
摘要: The present invention relates generally to antibodies cross-reactive with IL-17A and IL-17F, and bispecific anti-IL-17A/F and their uses.
摘要翻译: 本发明一般涉及与IL-17A和IL-17F交叉反应的抗体,以及双特异性抗IL-17A / F及其用途。
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公开(公告)号:US20100015135A1
公开(公告)日:2010-01-21
申请号:US12160084
申请日:2007-01-04
申请人: Yan Wu , Minhong Yan
发明人: Yan Wu , Minhong Yan
IPC分类号: A61K39/395 , C07K16/00 , C07H21/00 , C12N15/63 , C12N1/00 , C12N5/00 , C12P21/00 , G01N33/53 , A61K31/7052 , A61P35/00
CPC分类号: C07K16/2866 , A61K39/0011 , A61K2039/505 , C07K16/30 , C07K2317/33 , C07K2317/55 , C07K2317/76 , C07K2317/92
摘要: The invention provides anti-EphB4 antibodies, and compositions comprising and methods of using these antibodies.
摘要翻译: 本发明提供了抗EphB4抗体,组合物和使用这些抗体的方法。
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公开(公告)号:US20090304845A1
公开(公告)日:2009-12-10
申请号:US12134060
申请日:2008-06-05
申请人: Chih-Yu Chen , Jian-Guang Huang , Chun-Yan Wu
发明人: Chih-Yu Chen , Jian-Guang Huang , Chun-Yan Wu
IPC分类号: B28B7/10
CPC分类号: B29C45/4471 , B29C33/44
摘要: A demolding mechanism of mold includes a male mold, a swingable block and an elastic element. The male mold defines a receiving groove therein. The swingable block mounted in the receiving groove of the male mold has a pressing arm and a shaping arm connected with the pressing arm. The shaping arm defines a shaping portion for shaping a part of a product to be molded in the mold. The elastic element is resiliently disposed between the bottom of the pressing arm of the swingable block and the male mold for causing the swingable block to swing, which makes the product be disengaged from the shaping portion of the swingable block.
摘要翻译: 模具的脱模机构包括阳模,可摆动块和弹性元件。 阳模在其中限定接收槽。 安装在阳模的接收槽中的可摆动块具有与按压臂连接的按压臂和成形臂。 成形臂限定成形部分,用于使要在模具中成型的产品的一部分成形。 弹性元件弹性地设置在可摆动块的按压臂的底部和阳模之间,用于使摆动块摆动,这使得产品从摆动块的成形部分脱离。
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公开(公告)号:US20090279213A1
公开(公告)日:2009-11-12
申请号:US12151921
申请日:2008-05-09
申请人: Yan Wu , Glen Garfunkel , Min Li , Yuzuru Iwai , Moris Dovek
发明人: Yan Wu , Glen Garfunkel , Min Li , Yuzuru Iwai , Moris Dovek
IPC分类号: G11B5/33
CPC分类号: G11B5/3163 , G11B5/3912 , G11B5/398
摘要: A basic design is disclosed for bottom shield (S1) and top shield (S2) of the reader shields in a magnetic read-write head. The critical part of new design includes an antiferromagnetic film which pins an antiferromagnetically coupled trilayer (AFCT). The simplest embodiment for top shield, for example, would be a film sequence of FM/Ru/FM/AFM. This replaces the normal top shield design which typically comprises a ferromagnetic seed layer and a thicker plated ferromagnetic film. Processes for manufacturing these shields are also described.
摘要翻译: 公开了一种读写器的屏蔽罩(S1)和屏蔽罩(S2)在磁读写头中屏蔽的基本设计。 新设计的关键部分包括引导反铁磁耦合三层(AFCT)的反铁磁膜。 例如,用于顶部屏蔽的最简单的实施例将是FM / Ru / FM / AFM的胶片序列。 这代替通常的顶层屏蔽设计,其通常包括铁磁种子层和较厚的镀层铁磁膜。 还描述了用于制造这些屏蔽的工艺。
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公开(公告)号:US20090047291A1
公开(公告)日:2009-02-19
申请号:US12184969
申请日:2008-08-01
申请人: Daniel K. Kirchhofer , Yan Wu
发明人: Daniel K. Kirchhofer , Yan Wu
IPC分类号: A61K39/395 , C07K16/18
CPC分类号: C07K16/22 , C07K16/32 , C07K16/40 , C07K2317/21 , C07K2317/24 , C07K2317/54 , C07K2317/565 , C07K2317/76 , C07K2317/92
摘要: The invention provides methods and compositions for modulating hepatocyte growth factor activator function.
摘要翻译: 本发明提供调节肝细胞生长因子激活功能的方法和组合物。
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公开(公告)号:US20080263413A1
公开(公告)日:2008-10-23
申请号:US12100355
申请日:2008-04-09
申请人: Massimo Sorbara , Patrick Duvaut , Yan Wu
发明人: Massimo Sorbara , Patrick Duvaut , Yan Wu
IPC分类号: G06F11/07
摘要: Included are embodiments for back channel communication. At least one embodiment of a method includes receiving data at customer premises equipment and determining at least one error in the received data. Some embodiments include formatting the determined error for communication to a central office and sending the formatted error to the central office via a back channel.
摘要翻译: 包括用于反向信道通信的实施例。 方法的至少一个实施例包括在客户驻地设备处接收数据并确定接收到的数据中的至少一个错误。 一些实施例包括将所确定的错误格式化为中央局的通信,并通过后向信道将格式化的错误发送到中心局。
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