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公开(公告)号：US20100077395A1
公开(公告)日：2010-03-25
申请号：US12400510
申请日：2009-03-09
申请人： Aled Edwards , Anna Fischer , Patrick Goldsack
发明人： Aled Edwards , Anna Fischer , Patrick Goldsack
CPC分类号： H04L12/66 , H04L41/5012 , H04L67/10 , H04L69/40
摘要： A data center can share processing resources using virtual networks. A hosting program 9,10 hosts one or more virtual machines 11, 12. The program has a virtual interface VIF 1 14, to the virtual machines, a network interface 19 to enable communication between the virtual machines and other nodes of a network, and an infrastructure management interface 8, invisible to the virtual machines. The program has an intercept function 7 implemented as a comparator, switch or router, arranged to intercept a status message from one of the virtual machines, or applications run by that virtual machine. The status indication is sent to a status buffer 5 and is made available to the infrastructure management interface without providing a network path between the management interface and the virtual machine. This can discriminate between VM failure and communication failure, and the invisibility maintains isolation and helps avoid vulnerability to denial of service attack.
摘要翻译： 数据中心可以使用虚拟网络共享处理资源。 托管程序9,10托管一个或多个虚拟机11,12。该程序具有到虚拟机的虚拟接口VIF144，网络接口19，以实现虚拟机与网络的其他节点之间的通信，以及 虚拟机不可见的基础架构管理接口8。 该程序具有实现为比较器，交换机或路由器的拦截功能7，其被布置成从虚拟机之一或由该虚拟机运行的应用程序截取状态消息。 状态指示被发送到状态缓冲器5，并且可用于基础设施管理接口，而不在管理接口和虚拟机之间提供网络路径。 这可以区分VM故障和通信故障，并且不可见性保持隔离，并有助于避免拒绝服务攻击的漏洞。
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公开(公告)号：US06451591B1
公开(公告)日：2002-09-17
申请号：US09720272
申请日：2001-03-12
申请人： Aled Edwards
发明人： Aled Edwards
IPC分类号： C12M122
CPC分类号： C12Q1/37 , C07K1/12 , G01N33/68 , G01N33/6803 , Y10S435/97 , Y10S435/975
摘要： A method and device to assist in the determination of protein domain boundaries is described. In particular the device is designed to provide a high throughput of proteolytic digestion of proteins to identify domains and their boundaries, for use in protein structure determination, in a manner that is amenable to automation. Proteases are immobilized in a convenient format such as a microtitre plate and preferably arranged in a matrix thereby allowing for simultaneous degradation of a protein by a number of proteases at a number of concentrations.
摘要翻译： 描述了一种有助于确定蛋白质结构域边界的方法和装置。 特别地，该装置被设计为提供蛋白质的高通量的蛋白质水解消化，以便以适于自动化的方式鉴定结构域及其边界，以用于蛋白质结构测定。 蛋白酶以方便的形式如微量滴定板固定，并优选排列在基质中，从而允许多种蛋白质以多种浓度同时降解蛋白质。
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33.发明授权Persistent volume at an offset of a virtual block device of a storage server 有权在存储服务器的虚拟块设备的偏移处的持久卷公开(公告)号：US09098325B2
公开(公告)日：2015-08-04
申请号：US13407050
申请日：2012-02-28
CPC分类号： G06F9/45558 , G06F9/5016 , G06F2009/45579
摘要： Example embodiments disclosed herein relate to a persistent volume at an offset of a virtual block device of a storage server. Example embodiments include requesting that a persistent volume be dissociated from a virtual block device in response to the termination of a virtual machine.
摘要翻译： 本文公开的示例实施例涉及存储服务器的虚拟块设备的偏移处的持久卷。 示例性实施例包括响应于虚拟机的终止请求将永久卷从虚拟块设备解离。
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公开(公告)号：US20150135178A1
公开(公告)日：2015-05-14
申请号：US14381453
申请日：2012-03-08
申请人： Anna Fischer , Aled Edwards , Patrick Goldsack
发明人： Anna Fischer , Aled Edwards , Patrick Goldsack
CPC分类号： G06F9/45533 , G06F9/54 , G06F2209/542 , H04L61/6022 , H04L67/10
摘要： In one implementation, a host platform implemented on a computing device hosting one or more virtual machines determines that a communication generated by a virtual machine and intended for another virtual machine is to be transmitted to a network appliance. Consequently, the host platform modifies the communication generated by the virtual machine.
摘要翻译： 在一个实施方式中，在承载一个或多个虚拟机的计算设备上实现的主机平台确定由虚拟机生成并且用于另一虚拟机的通信将被发送到网络设备。 因此，主机平台修改虚拟机生成的通信。
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公开(公告)号：US08627313B2
公开(公告)日：2014-01-07
申请号：US12400510
申请日：2009-03-09
申请人： Aled Edwards , Anna Fischer , Patrick Goldsack
发明人： Aled Edwards , Anna Fischer , Patrick Goldsack
IPC分类号： G06F9/455 , G06F15/173
CPC分类号： H04L12/66 , H04L41/5012 , H04L67/10 , H04L69/40
摘要： A data center can share processing resources using virtual networks. A hosting program 9,10 hosts one or more virtual machines 11, 12. The program has a virtual interface VIF 1 14, to the virtual machines, a network interface 19 to enable communication between the virtual machines and other nodes of a network, and an infrastructure management interface 8, invisible to the virtual machines. The program has an intercept function 7 implemented as a comparator, switch or router, arranged to intercept a status message from one of the virtual machines, or applications run by that virtual machine. The status indication is sent to a status buffer 5 and is made available to the infrastructure management interface without providing a network path between the management interface and the virtual machine. This can discriminate between VM failure and communication failure, and the invisibility maintains isolation and helps avoid vulnerability to denial of service attack.
摘要翻译： 数据中心可以使用虚拟网络共享处理资源。 托管程序9,10托管一个或多个虚拟机11,12。该程序具有到虚拟机的虚拟接口VIF144，网络接口19，以实现虚拟机与网络的其他节点之间的通信，以及 虚拟机不可见的基础架构管理接口8。 该程序具有实现为比较器，交换机或路由器的拦截功能7，其被布置成从虚拟机之一或由该虚拟机运行的应用程序截取状态消息。 状态指示被发送到状态缓冲器5，并且可用于基础设施管理接口，而不在管理接口和虚拟机之间提供网络路径。 这可以区分VM故障和通信故障，并且不可见性保持隔离，并有助于避免拒绝服务攻击的漏洞。
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36.发明申请公开(公告)号：US20130227552A1
公开(公告)日：2013-08-29
申请号：US13407050
申请日：2012-02-28
IPC分类号： G06F9/455
CPC分类号： G06F9/45558 , G06F9/5016 , G06F2009/45579
摘要： Example embodiments disclosed herein relate to a persistent volume at an offset of a virtual block device of a storage server. Example embodiments include requesting that a persistent volume be dissociated from a virtual block device in response to the termination of a virtual machine.
摘要翻译： 本文公开的示例实施例涉及存储服务器的虚拟块设备的偏移处的持久卷。 示例性实施例包括响应于虚拟机的终止请求将永久卷从虚拟块设备解离。
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公开(公告)号：US20130191850A1
公开(公告)日：2013-07-25
申请号：US13355114
申请日：2012-01-20
申请人： Anna Fischer , Aled Edwards , Patrick Goldsack
发明人： Anna Fischer , Aled Edwards , Patrick Goldsack
CPC分类号： G06F9/545 , G06F9/45558 , G06F21/53 , G06F21/606 , G06F2009/45595 , G06F2209/542
摘要： Disclosed herein is a technique that intercepts data transmitted from a first application executing in a first domain to a second application executing in a second domain.
摘要翻译： 本文公开了一种技术，其拦截从在第一域中执行的第一应用发送到在第二域中执行的第二应用的数据。
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公开(公告)号：US20100107162A1
公开(公告)日：2010-04-29
申请号：US12400491
申请日：2009-03-09
申请人： Aled Edwards , Anna Fischer , Chris Ian Dalton , Patrick Goldsack
发明人： Aled Edwards , Anna Fischer , Chris Ian Dalton , Patrick Goldsack
IPC分类号： G06F9/455 , G06F15/173
CPC分类号： G06F9/5077 , G06F9/546 , H04L29/12028 , H04L45/58 , H04L61/103 , H04L67/10 , H04L69/32
摘要： A data center can share processing resources using virtual networks. A virtual machine manager (10) hosts one or more virtual machines (11, 411), the virtual machines forming part of a segmented virtual network (34). Outgoing messages from the virtual machines have an intermediate destination address of an intermediate node in a local segment of the segmented virtual network, and the virtual machine manager has a router (18) for determining a new intermediate destination address outside the local segment, for routing the given outgoing message. By having the router as part of the virtual machine manager rather than having only a switch in the virtual machine manager, the need for virtual machines for implementing gateways is avoided. This can reduce the number of “hops” for the message between virtual entities hosted, and thus improve performance. This can help a service provider to share physical processing resources of a data center between different clients having their own virtual networks.
摘要翻译： 数据中心可以使用虚拟网络共享处理资源。 虚拟机管理器（10）托管一个或多个虚拟机（11,411），所述虚拟机构成分段虚拟网络（34）的一部分。 来自虚拟机的传出消息具有分段虚拟网络的本地段中的中间节点的中间目的地址，并且虚拟机管理器具有用于确定本地段之外的新的中间目的地地址的路由器（18），用于路由 给定的传出消息。 通过将路由器作为虚拟机管理器的一部分，而不是在虚拟机管理器中只有交换机，则避免了为实现网关而需要虚拟机。 这可以减少托管的虚拟实体之间的消息的“跳数”，从而提高性能。 这可以帮助服务提供商在具有自己的虚拟网络的不同客户端之间共享数据中心的物理处理资源。
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公开(公告)号：US20060177837A1
公开(公告)日：2006-08-10
申请号：US11204186
申请日：2005-08-15
申请人： Ivan Borozan , Limin Chen , Aled Edwards , Elizabeth Heathcote , Ian McGilvray
发明人： Ivan Borozan , Limin Chen , Aled Edwards , Elizabeth Heathcote , Ian McGilvray
CPC分类号： C12Q1/6809 , C12Q1/6883 , C12Q1/706 , G06F19/3456 , G16B20/00 , G16B25/00 , G16B30/00 , G16B40/00 , G16B50/00 , Y02A90/22 , Y02A90/26 , C12Q2565/201
摘要： Systems and methods are provided for predicting patient response to a therapy regimen for a liver disease or a disease that is treatable with an immunomodulatory disease therapy using gene expression classifiers. Systems and methods for screening for modulators of target gene expression are also provided. Systems and methods for developing therapeutics against one or more of the proteins coded for by genes of the present invention are also provided. Systems and methods for predicting a patient response to a regimen of pegylated interferon alpha and ribavirin in a therapy for hepatitis C viral infection are also provided.
摘要翻译： 提供了系统和方法，用于预测患者对用于使用基因表达分类器的免疫调节疾病治疗可治疗的肝病或疾病的治疗方案的反应。 还提供了用于筛选靶基因表达调节剂的系统和方法。 还提供了用于开发针对由本发明的基因编码的一种或多种蛋白质的治疗剂的系统和方法。 还提供了用于在丙型肝炎病毒感染的治疗中预测患者对聚乙二醇化干扰素α和利巴韦林方案的反应的系统和方法。
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