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公开(公告)号：US09814820B2
公开(公告)日：2017-11-14
申请号：US14094306
申请日：2013-12-02
发明人： Robert W. Childers , David S. Brown , Ramesh Wariar , Sujatha Karoor , Shahid Din , Leo Martis , Cody Buchmann , Paul Soltys
CPC分类号： A61M1/1696 , A61M1/1656 , A61M1/1658 , A61M1/166 , A61M1/28 , A61M1/284 , A61M1/285 , A61M1/287 , A61M1/288 , A61M2202/0413 , A61M2205/12 , A61M2205/3306 , A61M2205/3327
摘要： A hemodialysis system including (i) a dialyzer, (ii) a blood circuit including a blood pump in fluid communication with the dialyzer, (iii) a dialysate circuit including a dialysate circulation pump in fluid communication with the dialyzer, the dialysate circuit further including a sorbent cartridge for cleaning used dialysate, (iv) a dialysate reservoir, (v) a reservoir pump in fluid communication with the dialysate circuit and the dialysate reservoir, (vi) a supply of concentrate for reconstituting dialysate in the dialysate circuit, and (vii) wherein the hemodialysis system is configured to electronically weigh the dialysate reservoir and the supply of concentrate.
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公开(公告)号：US09642961B2
公开(公告)日：2017-05-09
申请号：US14976773
申请日：2015-12-21
发明人： Thomas Kelly , Robert W. Childers , Don Busby , Rodolfo Roger , Waleed Musatem El Sayyid , Shahid Din
CPC分类号： A61M1/3621 , A61M1/1006 , A61M1/101 , A61M1/1012 , A61M1/1037 , A61M1/1039 , A61M1/1062 , A61M1/1081 , A61M1/1086 , A61M1/16 , A61M1/1601 , A61M1/1607 , A61M1/1613 , A61M1/1621 , A61M1/1629 , A61M1/1633 , A61M1/1635 , A61M1/1656 , A61M1/166 , A61M1/1668 , A61M1/167 , A61M1/1672 , A61M1/1696 , A61M1/267 , A61M1/288 , A61M1/341 , A61M1/3417 , A61M1/342 , A61M1/3427 , A61M1/3431 , A61M1/3434 , A61M1/3437 , A61M1/3444 , A61M1/3451 , A61M1/3458 , A61M1/3465 , A61M1/3468 , A61M1/3472 , A61M1/3486 , A61M1/3624 , A61M1/3626 , A61M1/3627 , A61M1/3643 , A61M1/3644 , A61M1/3646 , A61M1/3647 , A61M1/3649 , A61M1/365 , A61M1/3652 , A61M1/3656 , A61M2202/0413 , A61M2205/12 , A61M2205/13 , A61M2205/15 , A61M2205/18 , A61M2205/276 , A61M2205/3317 , A61M2205/3324 , A61M2205/3327 , A61M2205/3331 , A61M2205/3334 , A61M2205/3337 , A61M2205/3344 , A61M2205/3368 , A61M2205/3379 , A61M2205/3393 , A61M2205/3553 , A61M2205/3561 , A61M2205/3584 , A61M2205/502 , A61M2205/505 , A61M2205/52 , A61M2205/75
摘要： A renal failure therapy machine includes a blood cleaning filter, a sorbent device configured to regenerate used therapy fluid from the blood cleaning filter, a therapy fluid pump configured to pump regenerated therapy fluid from the sorbent device back to the blood cleaning filter, and a flow restrictor in fluid communication with the blood cleaning filter, the therapy fluid pump and the sorbent device, the flow restrictor configured to cause regenerated therapy fluid pumped by the therapy fluid pump from the sorbent device to the blood cleaning filter to be pressurized so that a first amount of the regenerated therapy fluid performs convective clearance and a second amount of the regenerated therapy fluid performs diffusive clearance.
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33.发明申请公开(公告)号：US20160263306A1
公开(公告)日：2016-09-15
申请号：US15163128
申请日：2016-05-24
发明人： Thomas Kelly , Robert W. Childers , Don Busby , Rodolfo Roger , Waleed Musatem El Sayyid , Shahid Din
CPC分类号： A61M1/3621 , A61M1/1006 , A61M1/101 , A61M1/1012 , A61M1/1037 , A61M1/1039 , A61M1/1062 , A61M1/1081 , A61M1/1086 , A61M1/16 , A61M1/1601 , A61M1/1607 , A61M1/1613 , A61M1/1621 , A61M1/1629 , A61M1/1633 , A61M1/1635 , A61M1/1656 , A61M1/166 , A61M1/1668 , A61M1/167 , A61M1/1672 , A61M1/1696 , A61M1/267 , A61M1/288 , A61M1/341 , A61M1/3417 , A61M1/342 , A61M1/3427 , A61M1/3431 , A61M1/3434 , A61M1/3437 , A61M1/3444 , A61M1/3451 , A61M1/3458 , A61M1/3465 , A61M1/3468 , A61M1/3472 , A61M1/3486 , A61M1/3624 , A61M1/3626 , A61M1/3627 , A61M1/3643 , A61M1/3644 , A61M1/3646 , A61M1/3647 , A61M1/3649 , A61M1/365 , A61M1/3652 , A61M1/3656 , A61M2202/0413 , A61M2205/12 , A61M2205/13 , A61M2205/15 , A61M2205/18 , A61M2205/276 , A61M2205/3317 , A61M2205/3324 , A61M2205/3327 , A61M2205/3331 , A61M2205/3334 , A61M2205/3337 , A61M2205/3344 , A61M2205/3368 , A61M2205/3379 , A61M2205/3393 , A61M2205/3553 , A61M2205/3561 , A61M2205/3584 , A61M2205/502 , A61M2205/505 , A61M2205/52 , A61M2205/75
摘要： A method for priming a hemodialysis treatment includes: providing a disposable cassette including at least a portion of a dialysate circuit and at least a portion of a blood circuit; placing a dialyzer in fluid communication with the dialysate circuit via a to-dialyzer dialysate line and a from-dialyzer dialysate line; placing the dialyzer in fluid communication with the blood circuit via an arterial blood line and a venous blood line; placing a source of dialysis fluid in fluid communication with the dialyzer; priming the dialysate circuit with dialysis fluid from the source while both the to-dialyzer dialysate line and the from-dialyzer dialysate line are connected at their dialyzer ends to the dialyzer; and priming the blood circuit with dialysis fluid from the source by actuating at least one valve provided by the disposable cassette.
摘要翻译： 用于引发血液透析治疗的方法包括：提供包括透析液回路的至少一部分和血液循环的至少一部分的一次性盒; 透析器通过透析器透析液线和透析器透析液线与透析液回路流体连通; 将透析器通过动脉血管和静脉血管与血液回路流体连通; 将透析液源与透析器流体连通; 在透析器透析液线路和透析器透析液线路的透析液端连接到透析器的同时用来自源的透析液引发透析液回路; 以及通过致动至少一个由一次性盒式磁带提供的阀，来自源的透析液引发血液循环。
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公开(公告)号：US20150297816A1
公开(公告)日：2015-10-22
申请号：US14754856
申请日：2015-06-30
发明人： Thomas Kelly , Robert W. Childers , Don Busby , Rodolfo Roger , Waleed Mutasem El Sayyid , Shahid Din
CPC分类号： A61M1/3621 , A61M1/1006 , A61M1/101 , A61M1/1012 , A61M1/1037 , A61M1/1039 , A61M1/1062 , A61M1/1081 , A61M1/1086 , A61M1/16 , A61M1/1601 , A61M1/1607 , A61M1/1613 , A61M1/1621 , A61M1/1629 , A61M1/1633 , A61M1/1635 , A61M1/1656 , A61M1/166 , A61M1/1668 , A61M1/167 , A61M1/1672 , A61M1/1696 , A61M1/267 , A61M1/288 , A61M1/341 , A61M1/3417 , A61M1/342 , A61M1/3427 , A61M1/3431 , A61M1/3434 , A61M1/3437 , A61M1/3444 , A61M1/3451 , A61M1/3458 , A61M1/3465 , A61M1/3468 , A61M1/3472 , A61M1/3486 , A61M1/3624 , A61M1/3626 , A61M1/3627 , A61M1/3643 , A61M1/3644 , A61M1/3646 , A61M1/3647 , A61M1/3649 , A61M1/365 , A61M1/3652 , A61M1/3656 , A61M2202/0413 , A61M2205/12 , A61M2205/13 , A61M2205/15 , A61M2205/18 , A61M2205/276 , A61M2205/3317 , A61M2205/3324 , A61M2205/3327 , A61M2205/3331 , A61M2205/3334 , A61M2205/3337 , A61M2205/3344 , A61M2205/3368 , A61M2205/3379 , A61M2205/3393 , A61M2205/3553 , A61M2205/3561 , A61M2205/3584 , A61M2205/502 , A61M2205/505 , A61M2205/52 , A61M2205/75
摘要： A renal therapy system includes: a filter; an arterial blood flowpath in fluid communication with the filter; a venous blood flowpath in fluid communication with the filter; a renal therapy fluid flowpath in fluid communication with the filter; first and second renal therapy fluid pumps; a plurality of valve actuators; and a dialysis fluid cassette including a plurality of valve portions configured to operate with the plurality of valve actuators so that (i) the first renal therapy fluid pump pumps renal therapy fluid through the renal therapy fluid flowpath for a number of first pump actuations, and (ii) the second renal therapy fluid pump pumps renal therapy fluid through the renal therapy fluid flowpath for a number of second pump actuations.
摘要翻译： 肾脏治疗系统包括：过滤器; 与过滤器流体连通的动脉血流径; 与过滤器流体连通的静脉血流路径; 与过滤器流体连通的肾脏治疗液流动路径; 第一和第二肾脏液体泵; 多个阀致动器; 以及透析液体盒，其包括多个阀部分，所述多个阀部分构造成与所述多个阀致动器一起操作，使得（i）所述第一肾脏治疗液体泵通过所述肾脏治疗流体流动路径泵送肾脏治疗液，用于多次第一泵动作，以及 （ii）第二肾脏治疗液体泵通过肾脏治疗液流路泵送肾脏治疗液，用于多次第二次泵动作。
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公开(公告)号：US10293096B2
公开(公告)日：2019-05-21
申请号：US15205268
申请日：2016-07-08
发明人： Thomas Kelly , Robert W. Childers , Don Busby , Rodolfo Roger , Waleed Mutasem El Sayyid , Shahid Din
摘要： A hemodialysis system includes a blood treatment machine, a blood pump housed by the blood treatment machine, a first dialysate pump housed by the blood treatment machine, a second dialysate pump housed by the blood treatment machine; and a fluid cassette including an upper portion and a lower portion. The fluid cassette further includes a blood pumping tube extending from the upper portion to the lower portion of the fluid cassette, a first dialysate pumping tube extending from the upper portion to the lower portion of the fluid cassette, and a second dialysate pumping tube extending from the upper portion to the lower portion of the fluid cassette.
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公开(公告)号：US20160317732A1
公开(公告)日：2016-11-03
申请号：US15205268
申请日：2016-07-08
发明人： Thomas Kelly , Robert W. Childers , Don Busby , Rodolfo Roger , Waleed Mutasem El Sayyid , Shahid Din
CPC分类号： A61M1/3621 , A61M1/1006 , A61M1/101 , A61M1/1012 , A61M1/1037 , A61M1/1039 , A61M1/1062 , A61M1/1081 , A61M1/1086 , A61M1/16 , A61M1/1601 , A61M1/1607 , A61M1/1613 , A61M1/1621 , A61M1/1629 , A61M1/1633 , A61M1/1635 , A61M1/1656 , A61M1/166 , A61M1/1668 , A61M1/167 , A61M1/1672 , A61M1/1696 , A61M1/267 , A61M1/288 , A61M1/341 , A61M1/3417 , A61M1/342 , A61M1/3427 , A61M1/3431 , A61M1/3434 , A61M1/3437 , A61M1/3444 , A61M1/3451 , A61M1/3458 , A61M1/3465 , A61M1/3468 , A61M1/3472 , A61M1/3486 , A61M1/3624 , A61M1/3626 , A61M1/3627 , A61M1/3643 , A61M1/3644 , A61M1/3646 , A61M1/3647 , A61M1/3649 , A61M1/365 , A61M1/3652 , A61M1/3656 , A61M2202/0413 , A61M2205/12 , A61M2205/13 , A61M2205/15 , A61M2205/18 , A61M2205/276 , A61M2205/3317 , A61M2205/3324 , A61M2205/3327 , A61M2205/3331 , A61M2205/3334 , A61M2205/3337 , A61M2205/3344 , A61M2205/3368 , A61M2205/3379 , A61M2205/3393 , A61M2205/3553 , A61M2205/3561 , A61M2205/3584 , A61M2205/502 , A61M2205/505 , A61M2205/52 , A61M2205/75
摘要： A hemodialysis system includes a blood treatment machine, a blood pump housed by the blood treatment machine, a first dialysate pump housed by the blood treatment machine, a second dialysate pump housed by the blood treatment machine; and a fluid cassette including an upper portion and a lower portion. The fluid cassette further includes a blood pumping tube extending from the upper portion to the lower portion of the fluid cassette, a first dialysate pumping tube extending from the upper portion to the lower portion of the fluid cassette, and a second dialysate pumping tube extending from the upper portion to the lower portion of the fluid cassette.
摘要翻译： 血液透析系统包括血液处理机，由血液处理机容纳的血液泵，由血液处理机容纳的第一透析液泵，由血液处理机容纳的第二透析液泵; 以及包括上部和下部的流体盒。 所述流体盒还包括从所述流体盒的上部延伸到下部的血液泵管，从所述流体盒的上部延伸到所述下部的第一透析液泵管，以及从所述流体盒延伸的第二透析液泵管 流体盒的下部的上部。
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公开(公告)号：US20160030657A1
公开(公告)日：2016-02-04
申请号：US14844767
申请日：2015-09-03
发明人： Thomas Kelly , Robert W. Childers , Don Busby , Rodolfo Roger , Waleed M. El Sayyid , Shahid Din
CPC分类号： A61M1/3621 , A61M1/1006 , A61M1/101 , A61M1/1012 , A61M1/1037 , A61M1/1039 , A61M1/1062 , A61M1/1081 , A61M1/1086 , A61M1/16 , A61M1/1601 , A61M1/1607 , A61M1/1613 , A61M1/1621 , A61M1/1629 , A61M1/1633 , A61M1/1635 , A61M1/1656 , A61M1/166 , A61M1/1668 , A61M1/167 , A61M1/1672 , A61M1/1696 , A61M1/267 , A61M1/288 , A61M1/341 , A61M1/3417 , A61M1/342 , A61M1/3427 , A61M1/3431 , A61M1/3434 , A61M1/3437 , A61M1/3444 , A61M1/3451 , A61M1/3458 , A61M1/3465 , A61M1/3468 , A61M1/3472 , A61M1/3486 , A61M1/3624 , A61M1/3626 , A61M1/3627 , A61M1/3643 , A61M1/3644 , A61M1/3646 , A61M1/3647 , A61M1/3649 , A61M1/365 , A61M1/3652 , A61M1/3656 , A61M2202/0413 , A61M2205/12 , A61M2205/13 , A61M2205/15 , A61M2205/18 , A61M2205/276 , A61M2205/3317 , A61M2205/3324 , A61M2205/3327 , A61M2205/3331 , A61M2205/3334 , A61M2205/3337 , A61M2205/3344 , A61M2205/3368 , A61M2205/3379 , A61M2205/3393 , A61M2205/3553 , A61M2205/3561 , A61M2205/3584 , A61M2205/502 , A61M2205/505 , A61M2205/52 , A61M2205/75
摘要： A dialysis system includes an extracorporeal circuit, a dialysis fluid circuit including first and second balance chambers, a fresh dialysis fluid pump in fluid communication with first and second fresh compartments of the first and second balance chambers, respectively. The first and second fresh compartments are in fluid communication with a fresh dialysate fluid inlet of the dialyzer, and a used dialysis fluid pump is in fluid communication with first and second spent compartments of the first and second balance chambers, respectively. The system is configured to run a blood rinseback sequence in which (i) at least one of the fresh used dialysis fluid pumps is operated to pump dialysis fluid through the dialyzer and into the extracorporeal circuit and (ii) the blood pump is operated to push blood back to a patient connected to the extracorporeal circuit.
摘要翻译： 透析系统包括体外回路，包括第一和第二平衡室的透析流体回路，分别与第一和第二平衡室的第一和第二新鲜隔室流体连通的新鲜透析流体泵。 第一和第二新鲜隔室与透析器的新鲜透析液流体入口流体连通，并且使用的透析液泵分别与第一和第二平衡室的第一和第二废隔间流体连通。 该系统被配置为运行血液冲洗序列，其中（i）至少一个新鲜使用的透析液泵被操作以将透析液体泵送通过透析器并进入体外回路，以及（ii）操作血泵来推动 血液回到连接到体外循环的患者身上。
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公开(公告)号：US08998839B2
公开(公告)日：2015-04-07
申请号：US13718600
申请日：2012-12-18
发明人： Robert W. Childers , David S. Brown , Ramesh Wariar , Sujatha Karoor , Shahid Din , Leo Martis , Cody Buckman , Paul Soltys
CPC分类号： A61M1/1696 , A61M1/1656 , A61M1/1658 , A61M1/166 , A61M1/28 , A61M1/284 , A61M1/285 , A61M1/287 , A61M1/288 , A61M2202/0413 , A61M2205/12 , A61M2205/3306 , A61M2205/3327
摘要： A regenerative peritoneal dialysis system includes a dialysis fluid loop; a filter located in the dialysis fluid loop, a first portion of the dialysis fluid sent to the filter rejected by the filter and returned upstream of the filter, a second portion of the dialysis fluid sent to the filter forming permeate, the permeate being rich in urea; and a urea removing apparatus located in the dialysis fluid loop downstream from the filter to receive the permeate and absorb urea from the permeate.
摘要翻译： 再生性腹膜透析系统包括透析液回路; 位于所述透析流体回路中的过滤器，所述透析流体的第一部分被输送到所述过滤器并被所述过滤器排出并返回到所述过滤器的上游，所述透析流体的第二部分被输送到过滤器形成渗透物，所述渗透物富含 尿素 以及尿素去除装置，其位于透析液回路的下游，用于接收渗透物并从渗透物吸收尿素。
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公开(公告)号：US20150088054A1
公开(公告)日：2015-03-26
申请号：US14568832
申请日：2014-12-12
发明人： Don Busby , Peter Hopping , Robert Childers , Shahid Din , Brian Lauman , Rick Kienman , Ian Richardson , Joseph H. Bowman, JR. , Loren M. Lundtveit , Jose Alvaro , Bruce Ming-Da Eu , Sherwin Shang
CPC分类号： A61M1/28 , A61M1/1664 , A61M1/282 , A61M1/288 , A61M5/14224 , A61M5/145 , A61M5/14593 , A61M2205/12 , A61M2205/121 , A61M2205/122 , A61M2205/123 , A61M2205/125 , A61M2205/126 , A61M2205/127 , A61M2205/128 , A61M2205/50 , A61M2205/502 , A61M2205/505 , A61M2205/581 , A61M2205/583
摘要： An embodiment of a peritoneal dialysis system includes an enclosure, a door hingedly attached to the enclosure, a stepper motor housed by the enclosure, a solid pump piston in operable communication with the stepper motor and including a solid pump shaft attached to or integrally formed with a solid pump head, and a disposable unit contacting the enclosure and the door. The disposable unit includes a moveable membrane operable with the solid pump head. The stepper motor is configured to move the solid pump head towards and away from the disposable unit. The system further includes a position detection apparatus operable with the stepper motor and located to provide an output indicative of a position of the solid pump head relative to a reference position.
摘要翻译： 腹膜透析系统的一个实施例包括外壳，铰接地连接到外壳的门，由外壳容纳的步进马达，固体泵活塞，其与步进马达可操作地连通，并且包括固体泵轴，附接到或与 固体泵头，以及接触外壳和门的一次性单元。 一次性单元包括可与固体泵头一起操作的可移动膜。 步进电机被配置成将固体泵头朝向和远离一次性单元移动。 该系统还包括位置检测装置，其可与步进电机一起工作并且被定位成提供指示固体泵头相对于参考位置的位置的输出。
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公开(公告)号：US20150027936A1
公开(公告)日：2015-01-29
申请号：US14511908
申请日：2014-10-10
发明人： Thomas Kelly , Robert W. Childers , Don Busby , Rodolfo Roger , Waleed Mutasem El Sayyid , Shahid Din
CPC分类号： A61M1/3621 , A61M1/1006 , A61M1/101 , A61M1/1012 , A61M1/1037 , A61M1/1039 , A61M1/1062 , A61M1/1081 , A61M1/1086 , A61M1/16 , A61M1/1601 , A61M1/1607 , A61M1/1613 , A61M1/1621 , A61M1/1629 , A61M1/1633 , A61M1/1635 , A61M1/1656 , A61M1/166 , A61M1/1668 , A61M1/167 , A61M1/1672 , A61M1/1696 , A61M1/267 , A61M1/288 , A61M1/341 , A61M1/3417 , A61M1/342 , A61M1/3427 , A61M1/3431 , A61M1/3434 , A61M1/3437 , A61M1/3444 , A61M1/3451 , A61M1/3458 , A61M1/3465 , A61M1/3468 , A61M1/3472 , A61M1/3486 , A61M1/3624 , A61M1/3626 , A61M1/3627 , A61M1/3643 , A61M1/3644 , A61M1/3646 , A61M1/3647 , A61M1/3649 , A61M1/365 , A61M1/3652 , A61M1/3656 , A61M2202/0413 , A61M2205/12 , A61M2205/13 , A61M2205/15 , A61M2205/18 , A61M2205/276 , A61M2205/3317 , A61M2205/3324 , A61M2205/3327 , A61M2205/3331 , A61M2205/3334 , A61M2205/3337 , A61M2205/3344 , A61M2205/3368 , A61M2205/3379 , A61M2205/3393 , A61M2205/3553 , A61M2205/3561 , A61M2205/3584 , A61M2205/502 , A61M2205/505 , A61M2205/52 , A61M2205/75
摘要： A dialysis system includes a dialysis machine having a pump actuator, a valve actuator and a sorbent device, and a disposable cassette including (i) a housing having a dialyzer inlet port, a dialyzer outlet port, a pump portion configured to operate with the pump actuator, a valve portion configured to operate with the valve actuator, a venous port, and an arterial port, (ii) at least one dialyzer in fluid communication with the housing, the at least one dialyzer including a dialysate inlet, and a dialysate outlet; (iii) an arterial line for connecting to a patient, the arterial line connected to and extending externally from the arterial port of the housing; (iv) a venous line for connecting to a patient, the venous line connected to and extending externally from the venous port of the housing; and (v) first and second dialysate fluid connections in fluid communication with the sorbent device.
摘要翻译： 透析系统包括具有泵致动器，阀致动器和吸附器装置的透析机以及一次性盒，其包括（i）具有透析器入口端口，透析器出口端口的壳体，配置成与泵 致动器，构造成与阀致动器一起操作的阀部分，静脉端口和动脉端口，（ii）与壳体流体连通的至少一个透析器，所述至少一个透析器包括透析液入口和透析液出口 ; （iii）用于连接到患者的动脉线，连接到壳体的动脉端口并从外部延伸的动脉线; （iv）用于连接到患者的静脉线，所述静脉线与所述壳体的静脉端口连接并从所述静脉端口向外延伸; 和（v）与吸附装置流体连通的第一和第二透析液流体连接。
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