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公开(公告)号：US20240285836A1
公开(公告)日：2024-08-29
申请号：US18656202
申请日：2024-05-06
CPC分类号： A61M1/16 , A61M1/14 , A61M1/153 , A61M1/155 , A61M1/1561 , A61M1/15625 , A61M1/1565 , A61M1/1601 , A61M1/1605 , A61M1/1621 , A61M1/1649 , A61M1/166 , A61M1/168 , A61M1/1686 , A61M1/1688 , A61M1/28 , A61M1/281 , A61M1/3465 , A61M1/36225 , A61M1/362261 , A61M1/362265 , A61M1/3643 , A61M1/3644 , A61M1/3649 , A61M1/3652 , B01D61/243 , B01D61/244 , B01D61/30 , A61M1/1524 , A61M1/362227 , A61M1/362262 , A61M2205/128 , A61M2205/3313 , A61M2205/3331 , A61M2205/3334 , A61M2205/3344 , A61M2205/3379 , A61M2205/6036 , Y10T29/49826 , Y10T137/0396 , Y10T137/87893
摘要： A hemodialysis system is disclosed. The hemodialysis system includes a dialyzer and an online dialysate generation system comprising a water inlet line and a drain line. The hemodialysis system also includes a disposable set comprising a supply tube fluidly connected to online dialysate generation system and a dialysate pumping tube fluidly connected to the dialyzer. The hemodialysis system further includes a dialysis instrument comprising a dialysate pump head and a motor positioned and arranged to operate the dialysate pump head. The dialysis instrument operates the dialysate pump head to move fresh dialysate from the online dialysate generation system through the dialysate pumping tube to the dialyzer.
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公开(公告)号：US12064540B2
公开(公告)日：2024-08-20
申请号：US18452516
申请日：2023-08-18
CPC分类号： A61M1/1601 , A61M1/154 , A61M1/155 , A61M1/15625 , A61M1/1565 , A61M1/16 , A61M1/1621 , A61M1/1654 , A61M1/1694 , A61M1/267 , A61M1/3401 , A61M1/341 , A61M1/3413 , A61M1/3424 , A61M1/3609 , A61M1/3621 , A61M1/36224 , A61M1/36225 , A61M1/362263 , A61M1/362265 , A61M1/362266 , A61M1/3623 , A61M1/3638 , A61M1/3643 , A61M1/3644 , A61M1/3646 , A61M1/3649 , A61M1/365 , A61M1/3652 , A61M1/3672 , A61M1/1561 , A61M1/362261 , A61M2205/07 , A61M2205/12 , A61M2205/123 , A61M2205/125 , A61M2205/128 , A61M2205/15 , A61M2205/16 , A61M2205/3317 , A61M2205/3324 , A61M2205/3331 , A61M2205/3334 , A61M2205/3368 , A61M2205/36 , A61M2205/505 , A61M2205/82 , A61M2205/8218 , A61M2205/8225 , Y10T137/87893
摘要： The present invention generally relates to hemodialysis and similar dialysis systems, including a variety of systems and methods that would make hemodialysis more efficient, easier, and/or more affordable. One aspect of the invention is generally directed to new fluid circuits for fluid flow. In one set of embodiments, a hemodialysis system may include a blood flow path and a dialysate flow path, where the dialysate flow path includes one or more of a balancing circuit, a mixing circuit, and/or a directing circuit. Preparation of dialysate by the preparation circuit, in some instances, may be decoupled from patient dialysis. In some cases, the circuits are defined, at least partially, within one or more cassettes, optionally interconnected with conduits, pumps, or the like. In one embodiment, the fluid circuit and/or the various fluid flow paths may be at least partially isolated, spatially and/or thermally, from electrical components of the hemodialysis system. In some cases, a gas supply may be provided in fluid communication with the dialysate flow path and/or the dialyzer that, when activated, is able to urge dialysate to pass through the dialyzer and urge blood in the blood flow path back to the patient. Such a system may be useful, for example, in certain emergency situations (e.g., a power failure) where it is desirable to return as much blood to the patient as possible. The hemodialysis system may also include, in another aspect of the invention, one or more fluid handling devices, such as pumps, valves, mixers, or the like, which can be actuated using a control fluid, such as air. In some cases, the control fluid may be delivered to the fluid handling devices using an external pump or other device, which may be detachable in certain instances. In one embodiment, one or more of the fluid handling devices may be generally rigid (e.g., having a spheroid shape), optionally with a diaphragm contained within the device, dividing it into first and second compartments.
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公开(公告)号：US20240123132A1
公开(公告)日：2024-04-18
申请号：US18394189
申请日：2023-12-22
发明人： Kevin L. Grant , Michael J. Wilt , Brian D. Tracey , Brett A. Rudolf , David E. Collins , Lisa A. Gustin , James D. Dale , Jesse T. Bodwell
CPC分类号： A61M1/3653 , A61M1/14 , A61M1/1658 , A61M1/1682 , A61M1/1686 , A61M1/362227 , A61M1/36225 , A61M1/362261 , A61M1/362265 , A61M1/3643 , A61M1/3644 , A61M1/3647 , A61M1/3649 , A61M1/365 , A61M1/3652 , A61M1/3656 , A61M1/367 , A61M1/3672 , A61M1/168 , A61M1/36224 , A61M1/362266 , A61M2205/12 , A61M2205/121 , A61M2205/128
摘要： A drain cassette for a dialysis unit has a fluid channel between venous and arterial connection ports, and a valve may controllably open and close fluid communication between a drain outlet port and the venous connection port or the arterial connection port. A blood circuit assembly and drain cassette may be removable from the dialysis unit, e.g., by hand and without the use of tools. A blood circuit assembly may include a single, unitary member that defines portions of a pair of blood pumps, control valves, channels to accurately position flexible tubing for an occluder, an air trap support, and/or other portions of the assembly. A blood circuit assembly engagement device may assist with retaining a blood circuit assembly on the dialysis unit, and/or with removal of the assembly. An actuator may operate a retainer element and an ejector element that interact with the assembly.
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公开(公告)号：US20240042116A1
公开(公告)日：2024-02-08
申请号：US18132601
申请日：2023-04-10
申请人： Novaflux, Inc.
CPC分类号： A61M1/3643 , B01D63/02 , A61M1/34 , B01D63/022 , A61M1/365 , B01D69/00 , A61M1/3644 , A61M1/3646 , A61M1/3649 , A61M1/3647 , B01D61/14
摘要： Embodiments of the invention pertain to cartridges, systems and methods for performing hemodialysis and related extracorporeal blood treatment modalities and therapies, in which blood flows in the inter fiber space and dialysate flows in the lumens of hollow fibers. Appropriate connectors and fitting orientations may be provided. There may be provided orbital distributors, fanning of fibers, and features to promote uniformity of fiber spacing in the fiber bundle. Orbital distributors may contain contoured surfaces, flow redirectors, non-uniform-conductance flow elements, through-wall distributors, and other features. There may be subdivision of the fiber bundle into two groups of fibers with separate control fluid to each group. Appropriate systems may be provided for various therapies. Flow past the fibers may be parallel, transverse or other configuration. These various features may enable long-term application to all dialysis and ultrafiltration related therapies, and also to other therapies and to applications including implantables, portables and wearables.
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公开(公告)号：US11890403B2
公开(公告)日：2024-02-06
申请号：US17026804
申请日：2020-09-21
发明人： Kevin L. Grant , Michael J. Wilt , Brian D. Tracey , Brett A. Rudolf , David E. Collins , Lisa A. Gustin , James D. Dale , Jesse T. Bodwell
CPC分类号： A61M1/3653 , A61M1/14 , A61M1/1658 , A61M1/1682 , A61M1/1686 , A61M1/365 , A61M1/367 , A61M1/3643 , A61M1/3644 , A61M1/3647 , A61M1/3649 , A61M1/3652 , A61M1/3656 , A61M1/3672 , A61M1/36225 , A61M1/362227 , A61M1/362261 , A61M1/362265 , A61M1/168 , A61M1/36224 , A61M1/362266 , A61M2205/12 , A61M2205/121 , A61M2205/128
摘要： A drain cassette for a dialysis unit has a fluid channel between venous and arterial connection ports, and a valve may controllably open and close fluid communication between a drain outlet port and the venous connection port or the arterial connection port. A blood circuit assembly and drain cassette may be removable from the dialysis unit, e.g., by hand and without the use of tools. A blood circuit assembly may include a single, unitary member that defines portions of a pair of blood pumps, control valves, channels to accurately position flexible tubing for an occluder, an air trap support, and/or other portions of the assembly. A blood circuit assembly engagement device may assist with retaining a blood circuit assembly on the dialysis unit, and/or with removal of the assembly. An actuator may operate a retainer element and an ejector element that interact with the assembly.
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公开(公告)号：US20240009368A1
公开(公告)日：2024-01-11
申请号：US18022933
申请日：2021-08-24
申请人： B. Braun Avitum AG
发明人： André Wagner
IPC分类号： A61M1/36
CPC分类号： A61M1/3649
摘要： An extracorporeal blood treatment device and method for priming and rinsing an extracorporeal blood treatment device. The extracorporeal blood treatment device includes an extracorporeal circuit, a dialyzer, and a dialyzing liquid circuit. The extracorporeal blood treatment device is configured for priming and rinsing the extracorporeal circuit, dialyzer and dialyzing liquid circuit. An arterial section and a venous section of the extracorporeal circuit are connected by a connector device. A control unit of the extracorporeal blood treatment device is configured to control the priming such that a liquid is supplied from the dialyzing liquid circuit via the dialyzer to the extracorporeal circuit and to control the rinsing such that it occurs via a created pressure difference between the extracorporeal circuit and the dialyzing liquid circuit for causing a liquid transfer via the dialyzer, in particular from the extracorporeal circuit to the dialyzing liquid circuit.
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公开(公告)号：US20230302213A1
公开(公告)日：2023-09-28
申请号：US18024239
申请日：2021-08-30
发明人： Bernard Canaud
IPC分类号： A61M1/36
CPC分类号： A61M1/3649 , A61M1/3661 , A61M2205/3368
摘要： The present disclosure relates to a method for priming an extracorporeal blood circuit using a blood treatment apparatus comprising a dialysis liquid preparation system having, a source of water, a source of bicarbonate concentrate and a source of acid concentrate including sodium chloride while not having a source of sodium chloride only, the method including preparing a priming solution from said source (of water and said source of acid only to obtain an acid/water solution, wherein bicarbonate from the source of bicarbonate concentrate is absent from said solution, connecting an arterial line section of the extracorporeal blood circuit to an outlet of the dialysis liquid preparation system of the blood treatment apparatus, and filling the extracorporeal blood circuit with said priming solution.
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公开(公告)号：US11690961B2
公开(公告)日：2023-07-04
申请号：US16595176
申请日：2019-10-07
CPC分类号： A61M5/3202 , A61M1/3649 , A61M5/001 , A61M5/158 , A61M5/3295 , A61M2005/2488
摘要： A needle cap and a dialysis circuit priming device with increased safety and convenience in the cleaning and priming of a blood circuit are provided. According to the present invention, a needle cap is provided including two needle connecting parts, and a flow path connecting the two needle connecting parts. A dialysis circuit priming device is also provided including two needles, two needle connecting parts each arranged with the two needles respectively, and a flow path for connecting the two needle connecting parts.
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公开(公告)号：US10010663B2
公开(公告)日：2018-07-03
申请号：US13757693
申请日：2013-02-01
申请人： Medtronic, Inc.
CPC分类号： A61M1/1621 , A61M1/1601 , A61M1/1652 , A61M1/1656 , A61M1/1658 , A61M1/1664 , A61M1/1668 , A61M1/3465 , A61M1/3643 , A61M1/3644 , A61M1/3646 , A61M1/3649
摘要： A flow loop for hemodialysis, hemodiafiltration and hemofiltration for the treatment of pathological conditions such as End Stage Renal Disease (ESRD) that has a controlled compliant flow path for preparing fluids required for a hemodialysis therapy session from water. The controlled compliant flow path modifies water into any one of a solution for priming a hemodialysis system, a physiologically compatible solution for contacting blood, a physiologically compatible solution for infusion to a subject, and a solution for blood rinse back to a subject. The controlled compliant flow path has a means for selectively metering in and metering out fluid from the flow path.
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公开(公告)号：US09968725B2
公开(公告)日：2018-05-15
申请号：US15044194
申请日：2016-02-16
CPC分类号： A61M1/3643 , A61M1/16 , A61M1/1696 , A61M1/342 , A61M1/3437 , A61M1/3465 , A61M1/3644 , A61M1/3646 , A61M1/3647 , A61M1/3649 , A61M1/365 , A61M1/3652 , A61M1/3672 , A61M2205/128 , A61M2205/3324 , A61M2205/3331 , A61M2205/3368 , A61M2205/3372 , Y10T137/0491
摘要： The application is directed to an extracorporeal blood processing system capable of using dialysate to prime the system. A plastic molded compact manifold supports molded blood and dialysate fluidic pathways along with relevant sensors, valves and pumps. The compact manifold is also disposable in one embodiment and can be detachably installed in the dialysis machine. A two-way valve in the manifold is used to direct the dialysate flow through the blood circuit to prime the circuit for use in treatment.
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