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公开(公告)号：US20180168973A1
公开(公告)日：2018-06-21
申请号：US15840046
申请日：2017-12-13
Applicant: Colgate-Palmolive Company
Inventor： Mahmoud Hassan , Xiang Chen , Shyamala Pillai , Guofeng Xu , LaTonya Kilpatrick-Liverman , Suman Chopra , Robert Dicosimo , Mark S. Payne
CPC classification number: A61K8/66 , A61C19/066 , A61K8/06 , A61K8/22 , A61K8/31 , A61K8/37 , A61K8/375 , A61K8/44 , A61K8/442 , A61K8/4973 , A61K8/8147 , A61K8/817 , A61K8/8176 , A61K2800/48 , A61K2800/882 , A61Q11/00
Abstract: A two-phase oral care whitening composition including a hydrophobic phase and a hydrophilic phase, and methods for oral care whitening teeth with the same are provided. The hydrophobic phase may include a source of hydrogen peroxide and an acyl donor. The hydrophilic phase may include an enzyme that catalyzes the generation of peracetic acid between the source of hydrogen peroxide and the acyl donor. At least one of the hydrophobic phase and the hydrophilic phase may further include at least one surfactant.
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公开(公告)号：US09884000B2
公开(公告)日：2018-02-06
申请号：US14366436
申请日：2012-12-18
Inventor： Thomas J. Boyd , Guofeng Xu , Richard Adams , Robert Pierce , Steven Miller , David Viscio , Kari A. Fosser , Robert Dicosimo , Hong Wang
Abstract: Described herein are tooth whitening strips comprising an hydratable adhesive film having a granular bleaching ingredient attached thereto, wherein upon hydration, the granular bleaching ingredient releases hydrogen peroxide which is used by an enzyme catalyst having perhydrolytic activity to enzymatically produce an effective amount of peracid bleaching agent from an acyl donor substrate. Methods of making and use the tooth whitening strips are also provided.
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公开(公告)号：US09861563B2
公开(公告)日：2018-01-09
申请号：US14653876
申请日：2012-12-19
Applicant: Colgate-Palmolive Company
Inventor： LaTonya Kilpatrick-Liverman , Zhiqiang Liu , Long Pan , Ying Yang , Guofeng Xu , Michael A. Stranick , Zhigang Hao
CPC classification number: A61K8/27 , A61K8/21 , A61K8/416 , A61K8/44 , A61K2800/74 , A61Q11/00 , C07C229/12
Abstract: The invention provides oral care compositions comprising a mixture of tetrabasic zinc halide and trimethylglycine, in free or orally acceptable salt form. Methods of making and using the compositions are also provided.
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公开(公告)号：US20170172880A1
公开(公告)日：2017-06-22
申请号：US15375320
申请日：2016-12-12
Applicant: Colgate-Palmolive Company
Inventor： Stacey Lavender , Guofeng Xu , Cajetan Dogo-Isonagie
CPC classification number: A61K8/463 , A61K8/0204 , A61K8/022 , A61K8/19 , A61K8/23 , A61K8/36 , A61K8/365 , A61K8/8176 , A61K8/86 , A61K2800/222 , A61K2800/31 , A61K2800/594 , A61K2800/882 , A61Q11/00
Abstract: A solid composition for adding to water of an aqueous solution to form a whitening mouthrinse. The solid composition can be in the form of a tablet and contains a salt of peroxymonosulfate as a whitening agent.
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公开(公告)号：US20150265511A1
公开(公告)日：2015-09-24
申请号：US14364738
申请日：2012-12-18
Inventor： Thomas Boyd , Guofeng Xu , Richard Adams , Robert Pierce , Derek Samaroo , David Viscio , Kari A. Fosser , Robert Dicosimo , Hong Wang
CPC classification number: A61K8/38 , A61K8/042 , A61K8/22 , A61K8/375 , A61K8/66 , A61K2800/87 , A61K2800/882 , A61Q11/00 , B65D35/22 , B65D81/3261
Abstract: Described herein are packages for storing and dispensing multi-part tooth whitening formulations, comprising a deformable material configured to form two or more sealed chambers, e.g., wherein the first chamber contains a low viscosity liquid solution comprising an enzyme having perhydrolytic activity, and the second chamber contains a peroxide source and a at least one acyl donor substrate. Particular multi-part tooth whitening formulations using this principle and methods of use thereof are also provided.
Abstract translation: 本文描述的是用于存储和分配多部分牙齿美白配方的包装，其包括构造成形成两个或更多个密封室的可变形材料，例如，其中第一室含有包含具有过水解活性的酶的低粘度液体溶液， 室含有过氧化物源和至少一个酰基供体底物。 还提供了使用该原理的特定的多部分牙齿美白配方及其使用方法。
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Patent Agency Ranking
公开(公告)号：US20140312232A1
公开(公告)日：2014-10-23
申请号：US14322897
申请日：2014-07-02
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： Jennifer Gronlund , Guofeng Xu , Deborah A. Peru , Ravi Subramanyam
CPC classification number: G01N21/33 , A46B15/0002 , A46B15/0004 , A46B15/0034 , A46B2200/1066 , A61B5/0075 , A61B5/4547 , A61B5/4552 , A61B5/6887 , G01N21/359
Abstract: Improved analytical, diagnostic, monitoring, and other methods (and their associated devices) for evaluating the extent of deposition of an agent onto a substrate are described. Exemplary methods may be used in the in the monitoring of the dental health of patients or in the fast, efficient screening and/or characterization of formulations in terms of their use for depositing oral actives onto tooth surfaces. The methods involve the direct or in situ analysis of substrates, onto which agents are deposited, using Near-IR spectroscopy and/or UV spectroscopy.
Abstract translation: 描述了用于评估试剂沉积到基底上的程度的改进的分析，诊断，监测和其它方法（及其相关的装置）。 就口服活性成分在牙齿表面上的使用而言，可以使用示例性的方法来监测患者的牙齿健康状况，或用于快速有效地筛选和/或表征制剂。 该方法涉及使用近红外光谱和/或紫外光谱直接或原位分析沉积有试剂的底物。
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公开(公告)号：US08628264B2
公开(公告)日：2014-01-14
申请号：US13633409
申请日：2012-10-02
Applicant: Colgate-Palmolive Company
Inventor： Alan Sorrentino , Guofeng Xu , Richard Scott Robinson , Douglas J. Hohlbein
IPC: B43K5/14
CPC classification number: A46B11/0003 , A46B2200/1066 , A61K8/11 , A61K8/65 , A61K2800/56 , A61Q11/00
Abstract: An oral care implement includes a handle, a head mounted to one end of the handle that includes a first face having a plurality of tooth cleaning elements extending therefrom and a second face, a store of dentifrice retained at the head, and a film matrix retained at the head containing at least one rapidly releasable agent. A soft tissue cleaner can be included on the second face. The at least one rapidly releasable agent can be provided to the first and/or second faces during use from the film matrix. In addition, dentifrice can be provided to the first and/or second faces during use from the store of dentifrice. The at least one rapidly releasable agent can include, for example, a flavoring agent, a dentifrice, or a therapeutic agent. The toothbrush can be small in size and lightweight so as to be readily portable for use away from the home.
Abstract translation: 口腔护理器具包括手柄，头部安装在手柄的一端，该头部包括具有从其延伸的多个牙齿清洁元件的第一面和第二面，保留在头部的洁牙剂储存器，保留的薄膜矩阵 在头部含有至少一种快速释放的药剂。 软组织清洁剂可以包括在第二面上。 所述至少一种可快速释放的试剂可以在使用期间从膜基质提供给第一和/或第二面。 此外，在使用期间，洁牙剂可以在洁牙剂的存储处将洁牙剂提供给第一和/或第二面。 至少一种快速可释放的试剂可以包括例如调味剂，洁牙剂或治疗剂。 牙刷的尺寸和重量可以很小，以便便于携带，远离家庭使用。
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公开(公告)号：US11110042B2
公开(公告)日：2021-09-07
申请号：US16820909
申请日：2020-03-17
Applicant: Colgate-Palmolive Company
Inventor： Zhigang Hao , Paul Thomson , Long Pan , Tatiana Brinzari , Guofeng Xu , Sergio Leite , Yu Wang
Abstract: Disclosed herein are improved methods for the synthesis of stannous pyrophosphate, as well as improved methods for the manufacture of oral care compositions comprising stannous pyrophosphate.
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公开(公告)号：US20210267875A1
公开(公告)日：2021-09-02
申请号：US17303059
申请日：2021-05-19
Applicant: Colgate-Palmolive Company
Inventor： Rong Dong , Guofeng Xu
Abstract: A tooth whitening composition includes a hydrophobic copolymer, a hydrophilic whitening agent and a polar solvent.
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公开(公告)号：US10543154B2
公开(公告)日：2020-01-28
申请号：US15838486
申请日：2017-12-12
Applicant: Colgate-Palmolive Company
Inventor： Shaotang Yuan , Guofeng Xu , Robert Dicosimo , Sharon Haynie
Abstract: An oral care composition, including a non-aqueous dispersant and an amphiphilic copolymer structure-building agent.
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