公开(公告)号：US11837348B2

公开(公告)日：2023-12-05

申请号：US17933197

申请日：2022-09-19

Applicant: Dexcom, Inc.

Inventor： Anna Leigh Davis ,  Scott M. Belliveau ,  Naresh C. Bhavaraju ,  Leif N. Bowman ,  Rita M. Castillo ,  Alexandra Elena Constantin ,  Rian W. Draeger ,  Laura J. Dunn ,  Gary Brian Gable ,  Arturo Garcia ,  Thomas Hall ,  Hari Hampapuram ,  Christopher Robert Hannemann ,  Anna Claire Harley-Trochimczyk ,  Nathaniel David Heintzman ,  Andrea Jean Jackson ,  Lauren Hruby Jepson ,  Apurv Ullas Kamath ,  Katherine Yerre Koehler ,  Aditya Sagar Mandapaka ,  Samuel Jere Marsh ,  Gary A. Morris ,  Subrai Girish Pai ,  Andrew Attila Pal ,  Nicholas Polytaridis ,  Philip Thomas Pupa ,  Eli Reihman ,  Ashley Anne Rindfleisch ,  Sofie Wells Schunk ,  Peter C. Simpson ,  Daniel S. Smith ,  Stephen J. Vanslyke ,  Matthew T. Vogel ,  Tomas C. Walker ,  Benjamin Elrod West ,  Atiim Joseph Wiley

IPC: G16H20/17 ,  G16H50/20 ,  G06N20/00 ,  A61B5/00 ,  H04M1/72412 ,  A61B5/024 ,  A61B5/11 ,  A61B5/145 ,  A61B5/16 ,  G08B21/04 ,  G06N5/043 ,  A61M5/172 ,  G16H40/67 ,  G16H40/63

CPC classification number: G16H20/17 ,  A61B5/0022 ,  A61B5/024 ,  A61B5/1112 ,  A61B5/14517 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/165 ,  A61B5/4866 ,  A61B5/742 ,  A61B5/746 ,  A61M5/1723 ,  G06N5/043 ,  G06N20/00 ,  G08B21/0453 ,  G16H40/63 ,  G16H40/67 ,  G16H50/20 ,  H04M1/72412 ,  A61M2205/18 ,  A61M2205/3584 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/52 ,  A61M2205/581 ,  A61M2205/582 ,  A61M2205/8206 ,  A61M2230/201 ,  Y02A90/10

Abstract: Systems and methods are disclosed that provide smart alerts to users, e.g., alerts to users about diabetic states that are only provided when it makes sense to do so, e.g., when the system can predict or estimate that the user is not already cognitively aware of their current condition, e.g., particularly where the current condition is a diabetic state warranting attention. In this way, the alert or alarm is personalized and made particularly effective for that user. Such systems and methods still alert the user when action is necessary, e.g., a bolus or temporary basal rate change, or provide a response to a missed bolus or a need for correction, but do not alert when action is unnecessary, e.g., if the user is already estimated or predicted to be cognitively aware of the diabetic state warranting attention, or if corrective action was already taken.

公开(公告)号：US11690577B2

公开(公告)日：2023-07-04

申请号：US16884593

申请日：2020-05-27

Applicant: DexCom, Inc.

Inventor： Hari Hampapuram ,  Anna Leigh Davis ,  Naresh C. Bhavaraju ,  Apurv Ullas Kamath ,  Claudio Cobelli ,  Giovanni Sparacino ,  Andrea Facchinetti ,  Chiara Zecchin

IPC: A61B5/00 ,  A61B5/145

CPC classification number: A61B5/746 ,  A61B5/0004 ,  A61B5/0022 ,  A61B5/0031 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/4848 ,  A61B5/4866 ,  A61B5/7221 ,  A61B5/7275 ,  A61B5/002

Abstract: Systems and methods for providing sensitive and specific alarms indicative of glycemic condition are provided herein. In an embodiment, a method of processing sensor data by a continuous analyte sensor includes: evaluating sensor data using a first function to determine whether a real time glucose value meets a first threshold; evaluating sensor data using a second function to determine whether a predicted glucose value meets a second threshold; activating a hypoglycemic indicator if either the first threshold is met or if the second threshold is predicted to be met; and providing an output based on the activated hypoglycemic indicator.

公开(公告)号：US20230140651A1

公开(公告)日：2023-05-04

申请号：US18049924

申请日：2022-10-26

Applicant: Dexcom. Inc.

Inventor： Arturo Garcia ,  Peter C. Simpson ,  Apurv U. Kamath ,  Naresh C. Bhavaraju ,  Stephen J. Vanslyke

IPC: A61B5/00 ,  A61B5/145 ,  A61B5/1495

Abstract: Systems and methods are provided to calibrate an analyte concentration sensor within a biological system, generally using only a signal from the analyte concentration sensor. For example, at a steady state, the analyte concentration value within the biological system is known, and the same may provide a source for calibration. Similar techniques may be employed with slow-moving averages. Variations are disclosed.

公开(公告)号：US11600384B2

公开(公告)日：2023-03-07

申请号：US16445055

申请日：2019-06-18

Applicant: DexCom, Inc.

Inventor： Naresh C. Bhavaraju ,  Arturo Garcia ,  Phil Mayou ,  Thomas A. Peyser ,  Apurv Ullas Kamath ,  Aarthi Mahalingam ,  Kevin Sayer ,  Thomas Hall ,  Michael Robert Mensinger ,  Hari Hampapuram ,  David Price ,  Jorge Valdes ,  Murrad Kazalbash

IPC: G16H50/30 ,  G16H40/67 ,  A61M5/172 ,  A61M5/142 ,  G16H40/63 ,  G16H15/00 ,  G16H20/17 ,  G01N33/49 ,  G16H50/00

Abstract: Methods and apparatus, including computer program products, are provided for processing analyte data. In some example implementations, a method may include generating glucose sensor data indicative of a host's glucose concentration using a glucose sensor; calculating a glycemic variability index (GVI) value based on the glucose sensor data; and providing output to a user responsive to the calculated glycemic variability index value. The GVI may be a ratio of a length of a line representative of the sensor data and an ideal length of the line. Related systems, methods, and articles of manufacture are also disclosed.

公开(公告)号：US11450421B2

公开(公告)日：2022-09-20

申请号：US16904454

申请日：2020-06-17

Applicant: DexCom, Inc.

Inventor： Anna Leigh Davis ,  Scott M. Belliveau ,  Naresh C. Bhavaraju ,  Leif N. Bowman ,  Rita M. Castillo ,  Alexandra Elena Constantin ,  Rian Draeger ,  Laura J. Dunn ,  Gary Brian Gable ,  Arturo Garcia ,  Thomas Hall ,  Hari Hampapuram ,  Christopher Robert Hannemann ,  Anna Claire Harley-Trochimczyk ,  Nathaniel David Heintzman ,  Andrea Jean Jackson ,  Lauren Hruby Jepson ,  Apurv Ullas Kamath ,  Katherine Yerre Koehler ,  Aditya Sagar Mandapaka ,  Samuel Jere Marsh ,  Gary A. Morris ,  Subrai Girish Pai ,  Andrew Attila Pal ,  Nicholas Polytaridis ,  Philip Thomas Pupa ,  Eli Reihman ,  Ashley Anne Rindfleisch ,  Sofie Wells Schunk ,  Peter C. Simpson ,  Daniel Smith ,  Stephen J. Vanslyke ,  Matthew T. Vogel ,  Tomas C. Walker ,  Benjamin Elrod West ,  Atiim Joseph Wiley

IPC: G16H20/17 ,  G16H50/20 ,  G06N20/00 ,  A61B5/00 ,  H04M1/72412 ,  A61B5/024 ,  A61B5/11 ,  A61B5/145 ,  A61B5/16 ,  G08B21/04 ,  G06N5/04 ,  A61M5/172 ,  G16H40/67 ,  G16H40/63

Abstract: Systems and methods are disclosed that provide smart alerts to users, e.g., alerts to users about diabetic states that are only provided when it makes sense to do so, e.g., when the system can predict or estimate that the user is not already cognitively aware of their current condition, e.g., particularly where the current condition is a diabetic state warranting attention. In this way, the alert or alarm is personalized and made particularly effective for that user. Such systems and methods still alert the user when action is necessary, e.g., a bolus or temporary basal rate change, or provide a response to a missed bolus or a need for correction, but do not alert when action is unnecessary, e.g., if the user is already estimated or predicted to be cognitively aware of the diabetic state warranting attention, or if corrective action was already taken.

公开(公告)号：US10737025B2

公开(公告)日：2020-08-11

申请号：US15684361

申请日：2017-08-23

Applicant: DexCom, Inc.

Inventor： Anna Leigh Davis ,  Scott M. Belliveau ,  Naresh C. Bhavaraju ,  Leif N. Bowman ,  Rita M. Castillo ,  Alexandra Elena Constantin ,  Rian Draeger ,  Laura J. Dunn ,  Gary Brian Gable ,  Arturo Garcia ,  Thomas Hall ,  Hari Hampapuram ,  Christopher Robert Hannemann ,  Anna Claire Harley-Trochimczyk ,  Nathaniel David Heintzman ,  Andrea J. Jackson ,  Lauren Hruby Jepson ,  Apurv Ullas Kamath ,  Katherine Yerre Koehler ,  Aditya Sagar Mandapaka ,  Samuel Jere Marsh ,  Gary A. Morris ,  Subrai Girish Pai ,  Andrew Attila Pal ,  Nicholas Polytaridis ,  Philip Thomas Pupa ,  Eli Reihman ,  Ashley Anne Rindfleisch ,  Sofie Wells Schunk ,  Peter C. Simpson ,  Daniel Smith ,  Stephen J. Vanslyke ,  Matthew T. Vogel ,  Tomas C. Walker ,  Benjamin Elrod West ,  Atiim Joseph Wiley

IPC: A61M5/172 ,  G16H50/20 ,  G06N20/00 ,  A61B5/00 ,  A61B5/024 ,  A61B5/11 ,  A61B5/145 ,  A61B5/16 ,  G06F19/00 ,  G08B21/04 ,  H04M1/725 ,  G06N5/04 ,  G16H20/17 ,  G16H40/67 ,  G16H40/63

Abstract: Systems and methods are disclosed that provide smart alerts to users, e.g., alerts to users about diabetic states that are only provided when it makes sense to do so, e.g., when the system can predict or estimate that the user is not already cognitively aware of their current condition, e.g., particularly where the current condition is a diabetic state warranting attention. In this way, the alert or alarm is personalized and made particularly effective for that user. Such systems and methods still alert the user when action is necessary, e.g., a bolus or temporary basal rate change, or provide a response to a missed bolus or a need for correction, but do not alert when action is unnecessary, e.g., if the user is already estimated or predicted to be cognitively aware of the diabetic state warranting attention, or if corrective action was already taken.

公开(公告)号：US10470661B2

公开(公告)日：2019-11-12

申请号：US15261816

申请日：2016-09-09

Applicant: DexCom, Inc.

Inventor： Arturo Garcia ,  Peter C. Simpson ,  Apurv Ullas Kamath ,  Naresh C. Bhavaraju ,  Stephen J. Vanslyke

IPC: A61B5/00 ,  A61B5/145 ,  A61B5/1495 ,  A61B5/11

Abstract: Systems and methods are provided to calibrate an analyte concentration sensor within a biological system, generally using only a signal from the analyte concentration sensor. For example, at a steady state, the analyte concentration value within the biological system is known, and the same may provide a source for calibration. Similar techniques may be employed with slow-moving averages. Variations are disclosed.

公开(公告)号：US10470660B2

公开(公告)日：2019-11-12

申请号：US15261711

申请日：2016-09-09

Applicant: DexCom, Inc.

Inventor： Arturo Garcia ,  Peter C. Simpson ,  Apurv Ullas Kamath ,  Naresh C. Bhavaraju ,  Stephen J. Vanslyke

IPC: A61B5/00 ,  A61B5/145 ,  A61B5/1495 ,  A61B5/11

Abstract: Systems and methods are provided to calibrate an analyte concentration sensor within a biological system, generally using only a signal from the analyte concentration sensor. For example, at a steady state, the analyte concentration value within the biological system is known, and the same may provide a source for calibration. Similar techniques may be employed with slow-moving averages. Variations are disclosed.

公开(公告)号：US20190261905A1

公开(公告)日：2019-08-29

申请号：US16412274

申请日：2019-05-14

Applicant: DexCom, Inc.

Inventor： Stephen J. Vanslyke ,  Naresh C. Bhavaraju ,  Lucas Bohnett ,  Arturo Garcia ,  Apurv Ullas Kamath ,  Jack Pryor

IPC: A61B5/1495 ,  G16H40/40

Abstract: Systems and methods for processing sensor data and calibration of the sensors are provided. In some embodiments, the method for calibrating at least one sensor data point from an analyte sensor comprises receiving a priori calibration distribution information; receiving one or more real-time inputs that may influence calibration of the analyte sensor; forming a posteriori calibration distribution information based on the one or more real-time inputs; and converting, in real-time, at least one sensor data point calibrated sensor data based on the a posteriori calibration distribution information.

公开(公告)号：US10362975B2

公开(公告)日：2019-07-30

申请号：US15394327

申请日：2016-12-29

Applicant: DexCom, Inc.

Inventor： Rui Ma ,  Naresh C. Bhavaraju ,  Thomas Stuart Hamilton ,  Jonathan Hughes ,  Jeff Jackson ,  David I-Chun Lee ,  Peter C. Simpson ,  Stephen J. Vanslyke

IPC: A61B5/1495 ,  G01N33/66 ,  A61B5/145 ,  A61B5/1486

Abstract: Systems and methods are disclosed which provide for a “factory-calibrated” sensor. In doing so, the systems and methods include predictive prospective modeling of sensor behavior, and also include predictive modeling of physiology. With these two correction factors, a consistent determination of sensitivity can be achieved, thus achieving factory calibration.