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公开(公告)号：US08267870B2
公开(公告)日：2012-09-18
申请号：US10452815
申请日：2003-05-30
申请人： Dominique M. Freeman , Dirk Boecker , Don Alden , Matt Schumann , Mike Beadman
发明人： Dominique M. Freeman , Dirk Boecker , Don Alden , Matt Schumann , Mike Beadman
CPC分类号： A61B5/157 , A61B5/1411 , A61B5/14532 , A61B5/1455 , A61B5/150022 , A61B5/150152 , A61B5/150167 , A61B5/150183 , A61B5/150305 , A61B5/150358 , A61B5/150412 , A61B5/150755 , A61B5/150824 , A61B5/15113 , A61B5/15117 , A61B5/15123 , A61B5/15151 , A61B5/15161 , A61B5/15169 , A61B5/15171 , A61B5/15176 , A61B5/15182
摘要： In one aspect, a body fluid sampling device is provided using a penetrating member to extract fluid from an anatomical feature. The device comprises a penetrating member actuator for moving the penetrating member inbound towards the anatomical feature and a non-spring based, penetrating member retractor for moving the penetrating member outbound away from the anatomical feature. The penetrating member actuator may be adapted to move the penetrating member at a velocity greater than a velocity achieved by the penetrating member retractor.
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公开(公告)号：US08062231B2
公开(公告)日：2011-11-22
申请号：US11548533
申请日：2006-10-11
申请人： Dirk Boecker , Don Alden , Dominique M. Freeman
发明人： Dirk Boecker , Don Alden , Dominique M. Freeman
IPC分类号： A61B5/00
CPC分类号： G01N33/557 , A61B5/14532 , A61B5/14546 , A61B5/150022 , A61B5/150068 , A61B5/150099 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150213 , A61B5/150251 , A61B5/150358 , A61B5/150435 , A61B5/150503 , A61B5/150572 , A61B5/150809 , A61B5/150816 , A61B5/150824 , A61B5/15087 , A61B5/15107 , A61B5/15123 , A61B5/15151 , A61B5/15153 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/15178 , A61B5/157 , A61B17/32093 , A61M2005/004 , B01L3/5027 , B01L3/502715 , B01L2200/10 , B01L2300/0663 , B01L2300/18 , G01N33/4905
摘要： These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes a drive force generator and a penetrating member operatively coupled to the force generator. The force generator moves the member along a path out of a housing with a penetrating member exit, into the tissue site, stops in the tissue site, and withdraws out of the tissue site. The drive force generator is configured to be controlled to follow a predetermined velocity trajectory into the tissue and out of the tissue. A tissue stabilizing member is associated with the device and at least partially surrounds an impact location of the penetrating member on the tissue site.
摘要翻译： 本发明的这些和其它目的在体液采集系统中实现，该体液采样系统用于组织部位，其包括驱动力发生器和可操作地联接到力发生器的穿透构件。 力产生器沿着路径将构件沿着穿过构件出口的壳体移动到组织部位中，停止在组织部位中，并从组织部位抽出。 驱动力发生器被配置为被控制以遵循预定的速度轨迹进入组织并离开组织。 组织稳定构件与装置相关联并且至少部分地围绕穿刺构件在组织部位上的冲击位置。
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公开(公告)号：US07717863B2
公开(公告)日：2010-05-18
申请号：US10335240
申请日：2002-12-31
申请人： Dominique M. Freeman , Don Alden , Dirk Boecker
发明人： Dominique M. Freeman , Don Alden , Dirk Boecker
IPC分类号： A61B5/00
CPC分类号： G01N33/557 , A61B5/14532 , A61B5/14546 , A61B5/150022 , A61B5/150068 , A61B5/150099 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150213 , A61B5/150251 , A61B5/150358 , A61B5/150435 , A61B5/150503 , A61B5/150572 , A61B5/150809 , A61B5/150816 , A61B5/150824 , A61B5/15087 , A61B5/15107 , A61B5/15123 , A61B5/15151 , A61B5/15153 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/15178 , A61B5/157 , A61B17/32093 , A61M2005/004 , B01L3/5027 , B01L3/502715 , B01L2200/10 , B01L2300/0663 , B01L2300/18 , G01N33/4905
摘要： A tissue penetration device includes a penetrating member driver and a cartridge. A plurality of penetrating members are integrated with the cartridge. Each penetrating member is coupled to the penetrating member driver when advanced along a path into a tissue target. A penetrating member sensor is coupled to the plurality of penetrating members. The penetrating member sensor is configured to provide information relative to a depth of penetration of a penetrating member through a skin surface.
摘要翻译： 组织穿透装置包括穿透构件驱动器和盒。 多个穿透构件与盒一体化。 当沿着进入组织靶的路径前进时，每个穿透构件联接到穿透构件驱动器。 穿透构件传感器联接到多个穿透构件。 穿透构件传感器被配置为提供关于穿透构件穿过皮肤表面的穿透深度的信息。
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公开(公告)号：US07481776B2
公开(公告)日：2009-01-27
申请号：US10335259
申请日：2002-12-31
申请人： Dirk Boecker , Don Alden , Dominique M. Freeman
发明人： Dirk Boecker , Don Alden , Dominique M. Freeman
CPC分类号： A61B5/15178 , A61B5/14532 , A61B5/14546 , A61B5/150022 , A61B5/150068 , A61B5/150099 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150213 , A61B5/150251 , A61B5/150358 , A61B5/150435 , A61B5/150503 , A61B5/150572 , A61B5/150809 , A61B5/150816 , A61B5/150824 , A61B5/15087 , A61B5/15107 , A61B5/15123 , A61B5/15151 , A61B5/15153 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/157 , A61B17/32093 , A61M2005/004 , B01L3/5027 , B01L3/502715 , B01L2200/10 , B01L2300/0663 , B01L2300/18 , G01N33/4905 , G01N33/557
摘要： A skin penetrating system is provided with a drive force generator and a disposable housing member. A plurality of penetrating members are positioned in the disposable housing member. Each penetrating member is coupled to the drive force generator. A plurality of analyte detecting members are each associated with a penetrating member and are positioned in the disposable housing member. Each analyte detecting member is positioned in a sample chamber. The sample chambers have openings for transport of a body fluid into the sample chamber. Each analyte detecting member is configured to determine a concentration of an analyte in a body fluid. A user interface is configured to relay at least one of, skin penetrating performance or a skin penetrating setting.
摘要翻译： 皮肤穿透系统设置有驱动力发生器和一次性外壳构件。 多个穿透构件定位在一次性外壳构件中。 每个穿透构件联接到驱动力发生器。 多个分析物检测构件各自与穿透构件相关联并且被定位在一次性外壳构件中。 每个分析物检测构件定位在样品室中。 样品室具有用于将体液输送到样品室中的开口。 每个分析物检测构件被配置成确定体液中分析物的浓度。 用户界面被配置为中继皮肤穿透性能或皮肤穿透设置中的至少一种。
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公开(公告)号：US07291117B2
公开(公告)日：2007-11-06
申请号：US10335219
申请日：2002-12-31
申请人： Dirk Boecker , Don Alden , Dominique M. Freeman
发明人： Dirk Boecker , Don Alden , Dominique M. Freeman
IPC分类号： A61B5/00
CPC分类号： G01N33/557 , A61B5/14532 , A61B5/14546 , A61B5/150022 , A61B5/150068 , A61B5/150099 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150213 , A61B5/150251 , A61B5/150358 , A61B5/150435 , A61B5/150503 , A61B5/150572 , A61B5/150809 , A61B5/150816 , A61B5/150824 , A61B5/15087 , A61B5/15107 , A61B5/15123 , A61B5/15151 , A61B5/15153 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/15178 , A61B5/157 , A61B17/32093 , A61M2005/004 , B01L3/5027 , B01L3/502715 , B01L2200/10 , B01L2300/0663 , B01L2300/18 , G01N33/4905
摘要： These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes a voice coil based penetrating member driver. A plurality of penetrating members are included. A transport mechanism is configured to engage the cartridges. Each of the cartridges is operatively engaged with the penetrating member driver when moved into position by the transport mechanism.
摘要翻译： 本发明的这些和其它目的是在包括基于音圈的穿透构件驱动器的组织部位上使用的体液取样系统中实现的。 包括多个穿透构件。 传送机构被配置成接合盒。 当通过传送机构移动到位时，每个盒与穿透构件驱动器可操作地接合。
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公开(公告)号：US07175642B2
公开(公告)日：2007-02-13
申请号：US10237262
申请日：2002-09-05
IPC分类号： A61B17/14
CPC分类号： G01N33/557 , A61B5/14532 , A61B5/14546 , A61B5/150022 , A61B5/150068 , A61B5/150083 , A61B5/150099 , A61B5/150152 , A61B5/150167 , A61B5/15019 , A61B5/150213 , A61B5/150221 , A61B5/150229 , A61B5/150358 , A61B5/150412 , A61B5/150435 , A61B5/150503 , A61B5/150572 , A61B5/150809 , A61B5/150824 , A61B5/150832 , A61B5/15087 , A61B5/150916 , A61B5/150954 , A61B5/151 , A61B5/15111 , A61B5/15113 , A61B5/15117 , A61B5/15123 , A61B5/15146 , A61B5/15151 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/15174 , A61B5/15176 , A61B5/15184 , A61B5/15186 , A61B5/1519 , A61B5/15194 , A61B17/32093 , B01L3/5027 , B01L2200/10 , B01L2300/0663 , B01L2300/18 , G01N33/4905
摘要： A lancet driver is provided wherein the driver exerts a driving force on a lancet during a lancing cycle and is used on a tissue site. The driver comprises of a drive force generator for advancing the lancet along a path into the tissue site, and a sensor configured to detect lancet position along said path during the lancing cycle.
摘要翻译： 提供了一种刺血针驱动器，其中驾驶员在穿刺周期期间在柳叶刀上施加驱动力并且在组织部位上使用。 该驱动器包括：驱动力发生器，用于将刺血针沿着路径推进到组织部位;以及传感器，被配置为在穿刺周期期间沿着所述路径检测刺血针位置。
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公开(公告)号：USD523555S1
公开(公告)日：2006-06-20
申请号：US29180959
申请日：2003-05-02
申请人： Dieter Loerwald , Dirk Boecker , Don Alden , Dominique M. Freeman
设计人： Dieter Loerwald , Dirk Boecker , Don Alden , Dominique M. Freeman
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公开(公告)号：US09795334B2
公开(公告)日：2017-10-24
申请号：US11774778
申请日：2007-07-09
申请人： Dominique M. Freeman , Dirk Boecker , Don Alden , Jason Hegener
发明人： Dominique M. Freeman , Dirk Boecker , Don Alden , Jason Hegener
CPC分类号： A61B5/15146 , A61B5/1411 , A61B5/1427 , A61B5/14532 , A61B5/14865 , A61B5/150022 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150221 , A61B5/150343 , A61B5/150358 , A61B5/150412 , A61B5/150427 , A61B5/150503 , A61B5/150572 , A61B5/150755 , A61B5/15087 , A61B5/151 , A61B5/15113 , A61B5/15123 , A61B5/15151 , A61B5/15153 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/15176 , A61B5/15178 , A61B5/15184 , A61B5/15186 , A61B5/15194 , A61B5/157 , A61B5/6886 , A61M5/3295
摘要： A tissue penetrating system has a housing member, a plurality of penetrating members positioned in the housing member and a plurality of sample chambers. Each sample chamber is associated with a penetrating member. A tissue stabilizing member has a tissue interface surface configured to be applied to a tissue surface and provide for spontaneous flow of blood for sample capture. The tissue stabilizing member is coupled to the housing.
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公开(公告)号：US09144401B2
公开(公告)日：2015-09-29
申请号：US11302423
申请日：2005-12-12
申请人： Dominique M. Freeman , Don Alden , Michael Wittig , Dirk Boecker
发明人： Dominique M. Freeman , Don Alden , Michael Wittig , Dirk Boecker
CPC分类号： A61B5/157 , A61B5/1411 , A61B5/150022 , A61B5/150167 , A61B5/150175 , A61B5/150282 , A61B5/150427 , A61B5/150511 , A61B5/15123 , A61B5/15151 , A61B5/15161 , A61B5/411
摘要： Reducing the volume or drag on skin or sharpness of the penetrating member entering the wound during the cutting process will reduce the pain associated with lancing, and result in less power desired for retraction of the penetrating member from the skin. A variety of other penetrating member configuration as shown in the application.
摘要翻译： 减少在切割过程中进入伤口的穿透部件的皮肤或皮肤的锐度，减少与穿刺相关的疼痛，并且导致从皮肤回缩穿透部件所需的较少功率。 各种其他穿透成员配置如应用程序所示。
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公开(公告)号：US08808201B2
公开(公告)日：2014-08-19
申请号：US12014421
申请日：2008-01-15
申请人： Dirk Boecker , Don Alden , Dominique M. Freeman
发明人： Dirk Boecker , Don Alden , Dominique M. Freeman
IPC分类号： A61B5/00
CPC分类号： A61B5/1411 , A61B5/1427 , A61B5/14532 , A61B5/14546 , A61B5/1455 , A61B5/1486 , A61B5/150022 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150221 , A61B5/150358 , A61B5/150412 , A61B5/150427 , A61B5/150503 , A61B5/150519 , A61B5/150572 , A61B5/150664 , A61B5/150824 , A61B5/15087 , A61B5/150916 , A61B5/151 , A61B5/15113 , A61B5/15117 , A61B5/15123 , A61B5/1513 , A61B5/15146 , A61B5/15151 , A61B5/15153 , A61B5/15161 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/15178 , A61B5/15182 , A61B5/15184 , A61B5/15186 , A61B5/157 , A61M37/0015
摘要： These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes an electrically powered drive force generator. A penetrating member is operatively coupled to the force generator. The force generator moves the member along a path out of a housing having a penetrating member exit, into the tissue site, stops in the tissue site, and withdraws out of the tissue site. An analyte detecting member is positioned to receive fluid from a wound created by the penetrating member. The detection member is configured to determine a concentration of an analyte in the fluid using a sample of less than 1 μL of the fluid. A user interface is configured to relay at least one of, penetrating member performance or a penetrating member setting.
摘要翻译： 本发明的这些和其它目的是在包括电动驱动力发生器的组织部位上使用的体液取样系统中实现的。 穿透构件可操作地联接到力发生器。 力产生器将构件沿着路径移动离开具有穿透构件出口的壳体，进入组织部位，在组织部位停止，并从组织部位抽出。 分析物检测构件定位成从由穿透构件产生的伤口接收流体。 检测构件被配置为使用小于1μL的流体的样品来确定流体中的分析物的浓度。 用户界面被配置为中继穿透构件性能或穿透构件设置中的至少一种。
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