DRUG CORES FOR SUSTAINED RELEASE OF THERAPEUTIC AGENTS
    32.
    发明申请
    DRUG CORES FOR SUSTAINED RELEASE OF THERAPEUTIC AGENTS 有权
    用于持续释放治疗药物的药物

    公开(公告)号:US20120187594A1

    公开(公告)日:2012-07-26

    申请号:US13367823

    申请日:2012-02-07

    IPC分类号: B28B11/12

    摘要: A solid drug core insert can be manufactured by injecting a liquid mixture comprising a therapeutic agent and a matrix precursor into a sheath body. The injection can be conducted at subambient temperatures. The mixture is cured to form a solid drug-matrix core. The therapeutic agent can be a liquid at about room temperature that forms a dispersion of droplets in the matrix material. A surface of the solid drug core is exposed, for example by cutting the tube, and the exposed surface of the solid drug core releases therapeutic quantities of the therapeutic agent when implanted into the patient. In some embodiments, the insert body inhibits release of the therapeutic agent, for example with a material substantially impermeable to the therapeutic agent, such that the therapeutic quantities are released through the exposed surface, thereby avoiding release of the therapeutic agent to non-target tissues.

    摘要翻译: 可以通过将包含治疗剂和基质前体的液体混合物注入鞘体来制造固体药物核心插入物。 注射可以在低于环境温度下进行。 将混合物固化以形成固体药物基质核心。 治疗剂可以是在约室温下的液体,其形成液滴在基质材料中的分散体。 固体药物核心的表面例如通过切割管而暴露,并且固体药物核心的暴露表面在植入患者体内释放治疗剂量。 在一些实施方案中,插入体抑制治疗剂的释放,例如具有对治疗剂基本上不可渗透的材料,使得治疗量通过暴露表面释放,从而避免将治疗剂释放到非靶组织 。

    LEAK CAPTURE AND CONTAINMENT DEVICE
    34.
    发明申请
    LEAK CAPTURE AND CONTAINMENT DEVICE 审中-公开
    泄漏捕集和封存装置

    公开(公告)号:US20140209615A1

    公开(公告)日:2014-07-31

    申请号:US13946261

    申请日:2013-07-19

    IPC分类号: B65D47/40

    CPC分类号: E04D13/00

    摘要: A device for capturing, containing, and transporting liquid from a leak. The device may include a tank that may include wheels for easy transportation. The tank may include an opening at the top with a funnel attached to direct the liquid into the tank. The device may further include an outlet connected to the bottom of the tank. A hose may connect to the outlet to direct the liquid from the tank to a different area.

    摘要翻译: 用于从泄漏中捕获,容纳和运输液体的装置。 该装置可以包括可以包括用于容易运输的轮子的罐。 罐可以包括在顶部的开口,其中漏斗连接以将液体引导到罐中。 该装置还可以包括连接到罐的底部的出口。 软管可以连接到出口,以将液体从罐引导到不同的区域。

    Apparatus and methods for material capture and removal
    35.
    发明授权
    Apparatus and methods for material capture and removal 有权
    用于材料捕获和去除的装置和方法

    公开(公告)号:US08784333B2

    公开(公告)日:2014-07-22

    申请号:US12357037

    申请日:2009-01-21

    IPC分类号: A61B10/00 A61B17/22 A61D1/02

    CPC分类号: A61B10/0275 A61B10/04

    摘要: Catheters, kits, and methods are provided for removing material from a body lumen. The catheters and methods may be used in a variety of body lumens, including but not limited to coronary and other arteries. In general, the catheter has a cutting element that cuts material while the material is engaged by a material capture device on the catheter body. Preferably, the material capture device tensions the material during cutting, which reduces the amount of cutting force required. The material capture device typically follows a path that draws material into the catheter body. Preferably, but not necessarily, the material capture device may be arranged on the catheter body to advance along a path outwardly from the catheter body into the material and then inwardly towards the catheter body to tension the material. The cutting element on the catheter body moves between a first position and a second position to cut the material while in tension.

    摘要翻译: 提供导管,套件和方法用于从体腔去除材料。 导管和方法可以用于各种体腔,包括但不限于冠状动脉和其他动脉。 通常,导管具有切割材料,该切割元件在材料通过导管主体上的材料捕获装置接合时切割材料。 优选地,材料捕获装置在切割期间张紧材料,这减少了所需的切割力的量。 材料捕获装置通常遵循将材料拉入导管主体的路径。 优选但不是必需的,材料捕获装置可以布置在导管主体上,以沿着从导管主体向外的路径前进到材料中,然后向内朝向导管主体拉伸材料。 导管主体上的切割元件在第一位置和第二位置之间移动,以在张力下切割材料。

    EMBEDDED DOWEL INSERTS
    36.
    发明申请
    EMBEDDED DOWEL INSERTS 审中-公开
    嵌入式DOWEL插件

    公开(公告)号:US20140047787A1

    公开(公告)日:2014-02-20

    申请号:US13964834

    申请日:2013-08-12

    IPC分类号: E04C5/16 E04B1/48

    摘要: A dowel supporting device that includes a substantially hollow tube having a top end and a bottom end. An opening may be formed at the top end and a base may be formed at the bottom end. The base of the dowel supporting device may be fastened to a concrete deck. Concrete may be poured into the concrete deck. When dowels are ready to be used, the dowels may be inserted and secured to the dowel supporting device.

    摘要翻译: 一种定位销支撑装置,其包括具有顶端和底端的基本中空的管。 可以在顶端形成开口,并且底部可以形成在底端。 销钉支撑装置的底座可以固定在混凝土板上。 混凝土可以倒入混凝土甲板。 当销钉准备使用时,销钉可以插入并固定到销钉支撑装置。

    TEA KETTLE
    38.
    发明申请
    TEA KETTLE 失效
    茶壶

    公开(公告)号:US20120090813A1

    公开(公告)日:2012-04-19

    申请号:US13021768

    申请日:2011-02-06

    IPC分类号: A47J31/54 B67D7/82

    CPC分类号: A47J27/21166

    摘要: Embodiments of the present invention relate to an improved kettle using conduction and convection, yielding improved boiling efficiency and methods of making the same. In one embodiment, a tea kettle comprises a handle, a spout, and a voluminous container having at least one passageway positioned about an outer surface of an inner containment wall of the voluminous container, for allowing a heated fluid to pass therethrough and conductively heat the inner containment wall. In another embodiment, a tea kettle comprises a voluminous container comprising an inner containment wall having a surface comprising a plurality of curves, and an outer wall having a surface comprising a plurality of curves, wherein at least one passageway is defined between an outer surface of the inner containment wall and an inner surface of the outer wall, for allowing a heated fluid to pass therethrough and conductively heat the inner containment wall.

    摘要翻译: 本发明的实施方案涉及使用传导和对流的改进的釜,产生改善的沸腾效率及其制备方法。 在一个实施例中,茶壶包括手柄,喷口和大容量容器,其具有围绕容积容器的内部容纳壁的外表面定位的至少一个通道,用于允许加热的流体通过,并导电地加热 内围墙。 在另一个实施方案中,茶壶包括容积大的容器,其包括具有包括多个曲线的表面的内部容纳壁,以及具有包括多个曲线的表面的外壁,其中至少一个通道被限定在 内部容纳壁和外壁的内表面,用于允许加热的流体通过,并且导电地加热内部容纳壁。