公开(公告)号：US20080187749A1

公开(公告)日：2008-08-07

申请号：US11955725

申请日：2007-12-13

申请人： John J. Cael ,  Carol L. Knox ,  Jonathan M. Mack ,  Feng Wang ,  Robert S. Wenzinger

发明人： John J. Cael ,  Carol L. Knox ,  Jonathan M. Mack ,  Feng Wang ,  Robert S. Wenzinger

IPC分类号： B32B7/12

CPC分类号： C09K9/02 ,  G02B5/23 ,  G02B5/3033 ,  Y10T428/2848

摘要： Provided is an optical element having at least (a) a support polymeric film layer of film material having opposing first and second sides, (b) a second polymeric film layer having opposing first and second sides, the second layer including a film material exhibiting a light influencing property, and (c) optionally, an adhesive layer interposed between and connected to at least a portion of the first side of support layer (a) and the second side of second layer (b). The film material of support layer (a) and the film material of second layer (b) are the same or different.

摘要翻译： 提供了一种光学元件，其具有至少（a）具有相对的第一和第二侧的膜材料的支撑聚合物膜层，（b）具有相对的第一和第二侧的第二聚合物膜层，所述第二层包括显示出 以及（c）可选地，插入在支撑层（a）的第一侧和第二层（b）的第二侧的至少一部分之间并连接到其上的粘合剂层。 支撑层（a）的膜材料和第二层（b）的膜材料相同或不同。

公开(公告)号：US07361729B2

公开(公告)日：2008-04-22

申请号：US09956256

申请日：2001-09-20

申请人： James E. McGrath ,  Michael Hickner ,  Feng Wang ,  Yu-Seung Kim

发明人： James E. McGrath ,  Michael Hickner ,  Feng Wang ,  Yu-Seung Kim

IPC分类号： C08G75/20

CPC分类号： B01D71/82 ,  B01D69/141 ,  B01D71/64 ,  B01D71/68 ,  C08G73/10 ,  C08G75/23

摘要： Sulfonated polymers are made by the direct polymerization of a sulfonated monomer to form the sulfonated polymers. The types of sulfonated polymers may include polysulfones or polyimides. The sulfonated polymers can be formed into membranes that may be used in proton exchange membrane fuel cells or as ion exchange membranes. The membranes formed from the sulfonated polymers exhibit improved properties over that of Nafion®. A heteropoly acid may be added to the sulfonated polymer to form a nanocomposite membrane in which the heteropoly acid is highly dispersed. The addition of a heteropoly acid to the sulfonated polymer increases the thermal stability of the membrane, enhances the conductivity above 100° C., and reduces the water uptake of the membrane.

摘要翻译： 磺化聚合物通过磺化单体的直接聚合制成磺化聚合物。 磺化聚合物的类型可以包括聚砜或聚酰亚胺。 磺化聚合物可以形成为可用于质子交换膜燃料电池或作为离子交换膜的膜。 由磺化聚合物形成的膜表现出比Nafion（R）更好的性能。 可以将杂多酸加入到磺化聚合物中以形成杂多酸高度分散的纳米复合膜。 向磺化聚合物中加入杂多酸增加了膜的热稳定性，提高了100℃以上的电导率，并降低了膜的吸水率。

公开(公告)号：US07208389B1

公开(公告)日：2007-04-24

申请号：US10672311

申请日：2003-09-26

申请人： Adrianne K. Tipton ,  Brian G. Lu ,  Patrick A. Van Cleemput ,  Michelle T. Schulberg ,  Qingguo Wu ,  Haiying Fu ,  Feng Wang

发明人： Adrianne K. Tipton ,  Brian G. Lu ,  Patrick A. Van Cleemput ,  Michelle T. Schulberg ,  Qingguo Wu ,  Haiying Fu ,  Feng Wang

IPC分类号： H01L21/76

CPC分类号： H01L21/31695 ,  H01L21/02126 ,  H01L21/02203 ,  H01L21/02274 ,  H01L21/02348

摘要： Methods of preparing a porous low-k dielectric material on a substrate are provided. The methods involve the use of ultraviolet radiation to react with and remove porogen from a porogen containing precursor film, leaving a porous low-k dielectric matrix. Methods using oxidative conditions and non-oxidative conditions are described. The methods described may be used to remove porogen from porogen-containing precursor films. The porogen may be a hydrocarbon such as a terpene (e.g., alpha-terpinene) or a norbornene (e.g., ENB). The resulting porous low-k dielectric matrix can then be annealed to remove water and remaining silanols capped to protect it from degradation by ambient conditions, which methods will also be described.

摘要翻译： 提供了在衬底上制备多孔低k电介质材料的方法。 这些方法涉及使用紫外线辐射与含致孔剂的前体膜反应并除去致孔剂，留下多孔的低k电介质基质。 描述了使用氧化条件和非氧化条件的方法。 所描述的方法可用于从含致孔剂的前体膜中除去致孔剂。 致孔剂可以是烃，例如萜烯（例如α-萜品烯）或降冰片烯（例如ENB）。 然后可以将得到的多孔低k电介质基体退火以除去水和封闭的剩余硅烷醇，以保护其免受环境条件的退化，这些方法也将被描述。

公开(公告)号：US20070069825A1

公开(公告)日：2007-03-29

申请号：US11237268

申请日：2005-09-27

申请人： Keng Wong ,  Feng Wang

发明人： Keng Wong ,  Feng Wang

IPC分类号： H03K3/03

CPC分类号： G06F1/04

摘要： In some embodiments, a clock generator is provided that provides a generator clock. The clock generator comprises a first clock source to provide a first clock and a second clock source to provide a second clock whose frequency at least indirectly tracks a supply to a clock distribution network. The clock generator selectably provides as the generator clock the first clock when the second clock leads the first clock and the second clock when it lags behind the first clock. Other embodiments are claimed and disclosed herein.

摘要翻译： 在一些实施例中，提供了提供发生器时钟的时钟发生器。 时钟发生器包括提供第一时钟和第二时钟源的第一时钟源，以提供其频率至少间接跟踪到时钟分配网络的电源的第二时钟。 当第二个时钟引导第一个时钟时，时钟发生器可选地提供第一个时钟作为发生器时钟，而当第二个时钟滞后于第一个时钟时，时钟发生器可选择地提供第一个时钟。 本文要求保护和公开其它实施例。

公开(公告)号：US07181205B1

公开(公告)日：2007-02-20

申请号：US10943055

申请日：2004-09-16

申请人： Baker Scott ,  David Reed ,  Robert Grant Irvine ,  Feng Wang

发明人： Baker Scott ,  David Reed ,  Robert Grant Irvine ,  Feng Wang

IPC分类号： H04Q7/20

CPC分类号： H04W24/00

摘要： The amplitude and phase errors of the modulation and demodulation in a transceiver are corrected by a self-calibration procedure in which a test signal is applied to the baseband input of the transmitter, and the output of the modulator is looped back to the input of the demodulator. The amplitude and phase errors of the resulting signal at the baseband output of the receiver are detected, and the contributions of the transmitter and receiver to the errors are separated and resolved into amplitude and phase components. Adjustments are then made to the amplitude and phase balance in the transmit and receive signal paths to correct the errors.

摘要翻译： 收发器中的调制和解调的幅度和相位误差通过自校准程序来校正，其中测试信号被施加到发射机的基带输入，并且调制器的输出被环回到 解调器。 在接收机的基带输出端产生的信号的振幅和相位误差被检测到，发射机和接收机对误差的贡献被分离并分解成幅度和相位分量。 然后对发射和接收信号路径中的幅度和相位平衡进行调整，以纠正误差。

公开(公告)号：US06951916B2

公开(公告)日：2005-10-04

申请号：US10612104

申请日：2003-07-02

申请人： Adam Wieslaw Mazur ,  Feng Wang ,  Russell James Sheldon ,  Frank Hallock Ebetino

发明人： Adam Wieslaw Mazur ,  Feng Wang ,  Russell James Sheldon ,  Frank Hallock Ebetino

IPC分类号： A61K38/00 ,  A61K38/12 ,  A61K38/34 ,  A61P3/04 ,  A61P5/06 ,  A61P5/14 ,  A61P5/40 ,  A61P7/08 ,  A61P9/00 ,  A61P15/00 ,  A61P15/08 ,  A61P15/10 ,  A61P21/00 ,  A61P25/00 ,  A61P25/14 ,  A61P25/28 ,  A61P29/00 ,  A61P31/04 ,  A61P43/00 ,  C07K7/02 ,  C07K7/54 ,  C07K7/64 ,  C07K14/68 ,  C07K14/685 ,  C07K7/50

CPC分类号： C07K14/685 ,  A61K38/00 ,  C07K14/68

摘要： Disclosed are MC-4 and/or MC-3 receptor ligands having the formula: wherein B is a suitable linking group comprising a least one amino acid.

摘要翻译： 公开了具有下式的MC-4和/或MC-3受体配体：其中B是包含至少一个氨基酸的合适的连接基团。

公开(公告)号：US06925485B1

公开(公告)日：2005-08-02

申请号：US10155694

申请日：2002-05-24

申请人： Feng Wang ,  Jay Brandenburg ,  Ronan French ,  David C. Tracey

发明人： Feng Wang ,  Jay Brandenburg ,  Ronan French ,  David C. Tracey

IPC分类号： G06F17/30 ,  H04L29/08 ,  G06F13/17

CPC分类号： G06F17/30902 ,  H04L67/02 ,  H04L67/2847 ,  H04L67/2852

摘要： The present invention is directed to a proxy cache preloader. According to an embodiment of the present invention, a Hyper Text Transfer Protocol (HTTP) client intermediary having a proxy cache is used to provide multiple client computing devices with access to Internet data in the cache. When a device needs access to Internet data (i.e., a web page), a preloader/refresh mechanism is employed which uses a preloader algorithm. In one embodiment, the preloader algorithm checks to see if the current request is for an HTTP Uniform Resource Locator (URL). If not, the data is re-loaded into the proxy cache. If the current request is a request for HTTP, the preloader mechanism determines if optimization is enabled for the URL. If not, the data is re-loaded into the proxy cache. Otherwise, an information retrieval method (e.g., an HTTP GET) optimization algorithm is employed.

摘要翻译： 本发明涉及代理缓存预加载器。 根据本发明的实施例，使用具有代理高速缓存的超文本传输​​协议（HTTP）客户端中介器来向多个客户端计算设备提供对高速缓存中的因特网数据的访问。 当设备需要访问因特网数据（即，网页）时，使用预加载器/刷新机制，其使用预加载器算法。 在一个实施例中，预加载器算法检查以查看当前请求是否针对HTTP统一资源定位符（URL）。 如果没有，则将数据重新加载到代理缓存中。 如果当前请求是HTTP请求，则预加载器机制确定是否为URL启用了优化。 如果没有，则将数据重新加载到代理缓存中。 否则，采用信息检索方法（例如，HTTP GET）优化算法。

公开(公告)号：US20050065217A1

公开(公告)日：2005-03-24

申请号：US10861186

申请日：2004-06-04

申请人： Kevin Pinney ,  Feng Wang ,  Maria Mejia

发明人： Kevin Pinney ,  Feng Wang ,  Maria Mejia

IPC分类号： C07D209/12 ,  C07F9/24 ,  C07F9/572 ,  A61K31/16 ,  C07C235/20

CPC分类号： C07F9/247 ,  C07D209/12 ,  C07F9/5728

摘要： Trimethoxyphenyl substituted indole ligands have been discovered which demonstrate impressive cytotoxicity as well as a remarkable ability to inhibit tubulin polymerization. Such compounds as well as related derivatives are excellent clinical candidates for the treatment of cancer in humans. In addition, certain of these ligands, as pro-drugs, may well prove to be tumor selective vascular targeting and destruction chemotherapeutic agents or to have anti-angiogenesis activity resulting in the selective prevention and/or destruction of tumor cell vasculature.

摘要翻译： 已经发现了三甲氧基苯基取代的吲哚配体，其表现出令人印象深刻的细胞毒性以及抑制微管蛋白聚合的显着能力。 这些化合物以及相关衍生物是用于治疗人类癌症的优异临床候选物。 此外，作为前药的这些配体中的某些可能被证明是肿瘤选择性血管靶向和破坏化学治疗剂，或者具有导致选择性预防和/或破坏肿瘤细胞脉管系统的抗血管生成活性。

公开(公告)号：US06849656B1

公开(公告)日：2005-02-01

申请号：US10070484

申请日：2000-09-15

申请人： Kevin Pinney ,  Feng Wang ,  Mallinath Hadimani

发明人： Kevin Pinney ,  Feng Wang ,  Mallinath Hadimani

IPC分类号： C07D209/12 ,  C07F9/24 ,  C07F9/572 ,  A61K31/404

CPC分类号： C07F9/247 ,  C07D209/12 ,  C07F9/5728

摘要： Trimethoxyphenyl substituted indole ligands have been discovered which demonstrate impressive cytotoxicity as well as a remarkable ability to inhibit tubulin polymerization. Such compounds as well as related derivatives are excellent clinical candidates for the treatment of cancer in humans. In addition, certain of these ligands, as prodrugs, may well prove to be tumor selective vascular targeting and destruction chemotherapeutic agents or to have anti-angiogenesis activity resulting in the selective prevention and/or destruction of tumor cell vasculature.

摘要翻译： 已经发现了三甲氧基苯基取代的吲哚配体，其表现出令人印象深刻的细胞毒性以及抑制微管蛋白聚合的显着能力。 这些化合物以及相关衍生物是用于治疗人类癌症的优异临床候选物。 此外，作为前药的这些配体中的某些可以很好地证明是肿瘤选择性血管靶向和破坏化学治疗剂，或具有抗血管生成活性，导致选择性预防和/或破坏肿瘤细胞脉管系统。

公开(公告)号：US06613874B1

公开(公告)日：2003-09-02

申请号：US09537789

申请日：2000-03-29

申请人： Adam Wieslaw Mazur ,  Feng Wang ,  Russell James Sheldon ,  Frank Hallock Ebetino

发明人： Adam Wieslaw Mazur ,  Feng Wang ,  Russell James Sheldon ,  Frank Hallock Ebetino

IPC分类号： C07K750

CPC分类号： C07K14/685 ,  A61K38/00 ,  C07K14/68

摘要： Disclosed are cyclic peptide analogs that are MC-4 and/or MC-3 receptor ligands, the analogs having a structure according to Formula (I): wherein B, X, E, Z, D, G, M′, W, R, R1, R1′, R11, m, n, p and q are as described in the specification. The peptide analogs are useful in treating diseases that are mediated by the MC-4 and/or the MC-3 receptor. As such, the invention is directed to methods of treating body weight disorders, such as obesity, anorexia, and cachexia. The invention also relates to the treatment of CNS depression, behavior-related disorders, memory-related disorders, cardiovascular function, inflammation, sepsis, septic shock, cardiogenic shock, hypovolemic shock, sexual dysfunction, erectile dysfunction, muscle atrophy, diseases associated with nerve growth and repair, and intrauterine fetal growth. Also disclosed are pharmaceutical compositions comprising the peptide analogs of Formula (I).

摘要翻译： 公开了作为MC-4和/或MC-3受体配体的环肽类似物，该类似物具有式（I）的结构：其中B，X，E，Z，D，G，M'，W，R ，R1，R1'，R11，m，n，p和q如说明书中所述。 肽类似物可用于治疗由MC-4和/或MC-3受体介导的疾病。 因此，本发明涉及治疗体重障碍，例如肥胖症，厌食症和恶病质的方法。 本发明还涉及CNS抑郁症，行为相关障碍，记忆相关障碍，心血管功能，炎症，败血症，败血症休克，心源性休克，血容量不足休克，性功能障碍，勃起功能障碍，肌肉萎缩，与神经相关的疾病 生长和修复，宫内胎儿生长。 还公开了包含式（I）的肽类似物的药物组合物。