摘要:
The invention provides a rapid high throughput screening process to identify genotoxic compounds. This is accomplished by using a set of biomarker predictor genes that selectively screen for genotoxic or non-genotoxic compounds.
摘要:
A colorimetric measurement head, for determining the internal color of a non-opaque material, in particular the internal color of the human skin, includes an emitter which emits light, towards the material to be studied, and is separated by an opaque wall from a emitter which receives light which has penetrated into the material and which is reflected thereby. An external surface of the head, which is positioned at the material to be studied, and contacts this surface either by direct application against the surface, or with optical wetting. The light received by the detector comes from the interior of the material, whereas the light possibly reflected by the surface of the material or coming directly from the emitter cannot reach the detector because of the opaque separating wall.
摘要:
Fluid dispensing container (1) equipped with a dispensing valve (2) carrying an outlet (3) through which the fluid is dispensed during the actuation of a pushbutton carried by the valve; a conditioning chamber (4) of variable volume defined by a mobile wall (5a) subjected to the internal pressure of the container, communicates, on the one hand, with the dispensing valve (2) and, on the other hand, with the inside (18) of the container through a retarder means made in the form of a passage with high head loss. At the end of emptying of the conditioning chamber (4), the communication between the dispensing valve (2) and the inside (18) of the container is interrupted.
摘要:
A process is described which consists, in a first stage, in applying a composition based on a substance of vegetable or animal origin, a synthetic organic substance or a mineral substance, in suspension or in solution in a solvent and having a viscosity suitable for application to the hair, or as a powder, and making it possible to prevent or substantially to limit the passage of the dyestuffs and/or of the dyestuff precursors as far as the scalp, and, in a second stage, in dyeing the hair using one or more compositions, at least one of which contains either an oxidizable dyestuff or a direct dyestuff, the dyeing being followed, after an interval sufficient for coloring the hair, by rinsing and optionally by shampooing.
摘要:
Methods of treating individuals identified as having cancer using ATP citrate lyase inhibitor and/or tricarboxylate transporter inhibitor are disclosed. Methods of inducing apoptosis in cancer cells using an ATP citrate lyase inhibitor and/or tri-carboxylate transporter inhibitor are disclosed. of treating an individual who has cancer comprising the steps of identifying the cancer as having a high rate of aerobic glycolysis, and administering an ATP citrate lyase inhibitor and/or tricarboxylate transporter inhibitor are disclosed. Methods of treating individuals who have cancer using compounds that inhibit the expression of ATP citrate lyase or tricarboxylate transporter are disclosed. Methods of identifying a compound with anticancer activity are disclosed.
摘要:
A mechanism for declarative service domain federation uses a declarative approach to both the visibility aspect and the management aspect of service domain federation. Instead of manually exporting services, that is, selecting individual services from source domains to be visible in the target domain, using the present system, a federation architect uses a federation console to specify federation intent. The federation intent may include federation rule, query-based service group, and quality-of-service (QoS) policy. Based on the declared federation intent, a planning engine resolves the individual services based on the group query, generates the service visibility configuration, and creates the necessary service proxies and/or mediation objects to satisfy the goal. At runtime, a service monitor collects the performance metrics of federated services and dynamically adjusts the mediation/proxy configurations to maintain the QoS objectives specified by the federation architect.
摘要:
A method, device, and computer program product are provided for automatically generating connectivity configuration between domains by a device. A rule is received by the device. The rule is read by the device to determine a first domain invoking a service, a second domain having the service, and connectivity requirements for the first and second domains. A first proxy and a second proxy are automatically determined to fulfill the rule by the device. The first proxy is automatically assigned to the first domain and the second proxy is automatically assigned to the second domain.
摘要:
A system for providing flight accident insurance at low price and fixed coverage comprises means for limiting the number of policies that can be sold on any given flight to not more than a predetermined number. The predetermined number may be 20. The premium for the insurance is a function of the GDP of the country in which the airline operating said flight is domiciled such that said premium is a decreasing function of said GDP.