公开(公告)号：US20090214453A1

公开(公告)日：2009-08-27

申请号：US12086648

申请日：2006-12-11

申请人： Stefan Müller ,  Jurg Haase ,  Thomas Ehlis ,  Gilbert Kreyer ,  Jochen Giesinger ,  Martin Vogt

发明人： Stefan Müller ,  Jurg Haase ,  Thomas Ehlis ,  Gilbert Kreyer ,  Jochen Giesinger ,  Martin Vogt

IPC分类号： A61Q17/04 ,  C07D241/04

CPC分类号： C07D295/192 ,  A61K8/411 ,  A61K8/42 ,  A61K8/49 ,  A61K8/494 ,  A61K2800/43 ,  A61Q17/04

摘要： Disclosed is the use of an aqueous dispersion comprising (a) a micronized sparingly soluble organic compound which has a UV-Vis spectrum with a maximum from 380 to 420 nm; and (b) an anionic dispersing agent for protecting the human skin from browning and skin aging.

摘要翻译： 公开了包含（a）微波化的微溶有机化合物的水分散体的使用，其具有最大值为380至420nm的UV-Vis光谱; 和（b）用于保护人体皮肤免于褐变和皮肤老化的阴离子分散剂。

公开(公告)号：US07105479B2

公开(公告)日：2006-09-12

申请号：US10472791

申请日：2002-03-19

申请人： Thomas Ehlis ,  Robert Hochberg ,  Hauke Rohwer

发明人： Thomas Ehlis ,  Robert Hochberg ,  Hauke Rohwer

IPC分类号： C11D3/28

CPC分类号： C11D3/42 ,  C11D3/0015

摘要： Disclosed is a fabric rinse composition comprising a) 0.1 to 10% by weight of a UV absorber of formula (1), wherein A is a radical of formula (1a); B is a radical of formula (1c); (1d); (1e); (1f), (1g); (1b); (1i); (1k); (1l); or (1m); R1, R2, R3, R4, R5 and R6 are each independently of the others hydrogen, C1–C18alkyl; C5–C7-cycloalkyl; halogen; R9 is hydrogen C1–C12hydroxyalkyl; or C5–C7cycloalkyl; R7, R8 and R10 are each independently of the others hydrogen, C1–C18alkyl, C5–C7cycloalkyl, C1–C12hydroxyalkyl; X is halogen; a radical of formula (1s); or (1u); sulfate, phosphate, lactate, citrate, tartrate; R11 is C1–C12alkyl; C5–C7cycloalkyl or phenyl: x is from 0 to 10; and y is from 1 to 20; b) 5 to 25% by weight, based on the total weight of the composition of a fabric softener agent; and c) the remainder being substantially water

摘要翻译： 公开了一种织物漂洗组合物，其包含a）0.1至10重量％的式（1）的UV吸收剂，其中A为式（1a）的基团; B是式（1c）的基团; （1d）; （1e）; （1f），（1g）; （1b）; （1i）; （1k）; （1l）; 或（1m）; R 1，R 2，R 3，R 4，R 5和R 5， R 6各自独立地为氢，C 1 -C 18烷基; C 5 -C 7 - 环烷基; 卤素; R 9是氢C 1 -C 12羟烷基; 或C 5 -C 7环烷基; R 7，R 8和R 10各自独立地为氢，C 1 -C 3 C 18 -C 18烷基，C 5 -C 7环烷基，C 1 -C 12羟烷基，C 1 -C 12烷基， X是卤素; 式（1s）的基团; 或（1u）; 硫酸盐，磷酸盐，乳酸盐，柠檬酸盐，酒石酸盐; R 11是C 1 -C 12烷基; C 5 -C 7环烷基或苯基：x为0至10; y为1〜20; b）5至25重量％，基于织物柔软剂的组合物的总重量; 和c）其余部分基本上是水

公开(公告)号：US07066184B1

公开(公告)日：2006-06-27

申请号：US10130235

申请日：2000-11-07

申请人： Thomas Ehlis

发明人： Thomas Ehlis

IPC分类号： A61K7/06

CPC分类号： C08K5/3475 ,  A61K8/4966 ,  A61Q17/04 ,  C07D249/20

摘要： The use of benzotriazole UV absorbers of formula (1), wherein A is a radical of formula (1a); (1b); or (1c); B is a radical of formula (1d); (1e); (1f), (1g); (1h); (1i); (1k); (1l); (1m); or (1n); R1, R2, R3, R4, R5 and R6 are each independently of the others hydrogen, C1–C16alkyl; C5–C7cycloalkyl; halogen; R9 is hydrogen, C1–C12alkyl; or C5–C7cycloalkyl; R7, R8 and R10 are each independently of the others hydrogen, C1–C12alkyl C5–C7cycloalky, C1–C12hydroxyalkyl; X is halogen; a radical of formula (1s); (1t); or (1u); sulfate, phosphate, lactate, citrate, tartrate; R11 is C1–C12alkyl; or C5–C7cycloalkyl; R12 and R13 are each independently of the other hydrogen; or C1–C5alkyl; x is from 0 to 10; and y is from 1 to 20; in the cosmetic treatment of human hair for protection against UV radiation is described.

摘要翻译： 使用式（1）的苯并三唑UV吸收剂，其中A是式（1a）的基团; （1b）; 或（1c）; B是式（1d）的基团; （1e）; （1f），（1g）; （1h）; （1i）; （1k）; （11）; （1m）; 或（1n）; R 1，R 2，R 3，R 4，R 5和R 5， R 6各自独立地为氢，C 1 -C 16烷基; C 5 -C 7环烷基; 卤素; R 9是氢，C 1 -C 12烷基; 或C 5 -C 7环烷基; R 7，R 8和R 10各自独立地为氢，C 1 -C 3 C 12 -C 12烷基C 5 -C 7环烷基，C 1 -C 12羟烷基; X是卤素; 式（1s）的基团; （1t）; 或（1u）; 硫酸盐，磷酸盐，乳酸盐，柠檬酸盐，酒石酸盐; R 11是C 1 -C 12烷基; 或C 5 -C 7环烷基; R 12和R 13各自独立地为氢; 或C 1 -C 5烷基; x为0〜10; y为1〜20; 在描述用于防止UV辐射的人发的美容处理中。

公开(公告)号：US06495125B2

公开(公告)日：2002-12-17

申请号：US09755817

申请日：2001-01-05

申请人： Robert Wayne Glenn, Jr. ,  Alan Roy Katritzky ,  Eric Block ,  Matthew David Shair ,  Thomas Ehlis ,  Joseph Anthony Lupia

发明人： Robert Wayne Glenn, Jr. ,  Alan Roy Katritzky ,  Eric Block ,  Matthew David Shair ,  Thomas Ehlis ,  Joseph Anthony Lupia

IPC分类号： A61K706

CPC分类号： A61K8/898 ,  A61K8/46 ,  A61K8/49 ,  A61K8/4926 ,  A61K8/494 ,  A61K8/4946 ,  A61K8/4953 ,  A61K8/496 ,  A61K8/69 ,  A61K8/899 ,  A61Q3/00 ,  A61Q5/00 ,  A61Q5/10 ,  A61Q5/12 ,  A61Q11/00 ,  A61Q19/00

摘要： This invention relates to a topical composition for treating amino acid based substrates comprising a protected thiol compound having the formula R—(S—Pr)m where R is a functional group, S is sulfur, and Pr is a heterocyclic protecting group, and m is an integer between 1 and 100. The invention further relates to systems which comprise this protected thiol compound and an activating mechanism. The protected thiol compounds of the present invention may be used in hair care compositions, textile care compositions, cosmetic compositions, oral care compositions, skin care, nail care, laundry care, acne care and animal care compositions. Preferred embodiments of the present invention provide a modified UV absorber and a modified antioxidant, methods for making them and compositions conprising them.

摘要翻译： 本发明涉及一种用于处理氨基酸基底物的局部组合物，其包含具有所述方法的受保护的硫醇化合物，其中R为官能团，S为硫，Pr为杂环保护基，m为1至100之间的整数。 本发明还涉及包含该受保护的硫醇化合物和活化机理的体系。 本发明的受保护的硫醇化合物可以用于护发组合物，纺织品护理组合物，化妆品组合物，口腔护理组合物，护肤品，指甲护理，洗衣护理，痤疮护理和动物护理组合物中。 本发明的优选实施方案提供了改性的紫外线吸收剂和改性抗氧化剂，制备它们的方法和令人惊奇的组合物。

公开(公告)号：US09764169B2

公开(公告)日：2017-09-19

申请号：US13381965

申请日：2010-06-29

申请人： Julie Grumelard ,  Thomas Ehlis ,  Markus Hansch ,  Myriam Sohn

发明人： Julie Grumelard ,  Thomas Ehlis ,  Markus Hansch ,  Myriam Sohn

IPC分类号： A61Q17/04 ,  A61K8/37

CPC分类号： A61Q17/04 ,  A61K8/37

摘要： Disclosed is the use of a UV filter combination, comprising (a) a first UV filter selected from benzylidene malonates of formula (1), wherein R1 methyl; ethyl; propyl; or n-butyl; if R1 is methyl, then R is tert. butyl; formula (II); formula (III); a radical of formula (1a); or a radical of formula (1b); wherein R2 and R3, independently from each other are hydrogen; or methyl; R4 is methyl; ethyl; or n-propyl; R5 and R6 independently from each other are hydrogen; or C1-C3alkyl; if R1 is ethyl; propyl; or n-butyl, then R is isopropyl; and (b) a second UV filter selected from (b1) Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine; (b2) Butyl Methoxydibenzoylmethane; (b3)Diethylhexyl Butamido Triazone; (b4) Ethylhexyl Triazone; (b5) Diethylamino Hydroxy Benzoyl Hexyl Benzoate; (b6) Ethylhexyl Methoxycinnamate; (b7) Ethylhexyl Salicylate; (b8) Homosalate; (b9) Octocrylene; (b10) micronized Methylene Bis-Benzotriazolyl Tetramethylbutylphenol; (b11) Phenylbenzimidazole Sulfonic Acid; (b12) Titanium Dioxide; (b13) micronized Tris-Biphenyl Triazine; and (b14) micronized (2-{4-[2-(4-Diethylamino-2-hydroxy-benzoyl)-benzoyl]-piperazine-1-carbonyl}-phenyl)-(4-diethylamino-2-hydroxy-phenyl)-methanone;(b15) benzoicacid,4,4-[[3-[1,3,3,3-tetramethyl-1-[trimethylsilyl)oxy]-1-disiloxanyl]propyl]amino]-1,3,5-triazine-2,4-diyl]diimino]bis-, dibutyl ester wherein the UV filter combination comprises at least 2 UV filters of component (b1)-(b14); for the protection of human and animal hair and skin against UV radiation.

公开(公告)号：US20110311786A1

公开(公告)日：2011-12-22

申请号：US12529718

申请日：2008-03-05

申请人： Allan Francis Cunningham ,  Thomas Ehlis ,  Jean-Luc Birbaum ,  Pascal Hayoz ,  Kamalesh Pai Fondekar

发明人： Allan Francis Cunningham ,  Thomas Ehlis ,  Jean-Luc Birbaum ,  Pascal Hayoz ,  Kamalesh Pai Fondekar

IPC分类号： B41M5/28 ,  C08K5/3492 ,  B05D3/06 ,  C09D129/04 ,  C09D109/08 ,  B05D3/02 ,  C07D251/24 ,  C09D133/08

CPC分类号： B41M5/3335 ,  B41M5/3336 ,  C08K5/3492 ,  C09D5/26 ,  C09D7/41 ,  Y10T428/24802

摘要： The present invention provides heat-sensitive coating compositions, which comprise a colour developer of formula (1) or mixtures thereof wherein R can be hydrogen, C1-20-alkyl, C3-8-cycloalkyl, C2-10-alkenyl, aryl or SO3H, and R2 and R3 can be the same or different and can be hydrogen, halogen, C1-20-alkyl, C3-8-cyclo-alkyl, C2-10-alkenyl, aryl, OR6, NR7R8, SR9, SO3H or COOR10 and R4 and R5 can be the same or different, and can be hydrogen, halogen, C1-20-alkyl, C3-8-cyclo-alkyl, C2-10-alkenyl, aryl, OR6, NR7R8 or SR9, R6, R7, R8, R9 and R10 can be the same or different and can be hydrogen, C1-30-alkyl, C3-8-cycloalkyl, C2-10-alkenyl or aryl, wherein C1-20-alkyl can be unsubstituted or substituted with one or more C3-8-cycloalkyl, C2-10-alkenyl, phenyl, halogen, OR11, NR12R13, SR14, SO3H or COOR15, and aryl can be unsubstituted or substituted with one or more halogen, C1-10-alkyl, halogenated C1-10-alkyl, C3-8-cycloalkyl C2-10-alkenyl, phenyl, OR11, NR12R13, SR14, SO3H or COOR15, wherein R11, R12, R13, R14 and R15 can be the same or different and can be hydrogen, C1-10-alkyl, C3-8-cycloalkyl or C2-10-alkenyl, a process for the preparation of these compositions, a process of coating substrates with these compositions, substrates coated with these compositions, a process for preparing marked substrates using these compositions, marked substrates obtainable by the latter process, and certain colour developers.

摘要翻译： 本发明提供热敏涂料组合物，其包含式（1）的显色剂或其混合物，其中R可以是氢，C 1-20烷基，C 3-8 - 环烷基，C 2-10 - 烯基，芳基或SO 3 H ，R2和R3可以相同或不同，可以是氢，卤素，C 1-20烷基，C 3-8 - 环烷基，C 2-10 - 烯基，芳基，OR 6，NR 7 R 8，SR 9，SO 3 H或COOR 10和 R4和R5可以相同或不同，可以是氢，卤素，C 1-20烷基，C 3-8 - 环烷基，C 2-10 - 烯基，芳基，OR 6，NR 7 R 8或SR 9，R 6，R 7，R 8 ，R 9和R 10可以相同或不同，并且可以是氢，C 1-30 - 烷基，C 3-8 - 环烷基，C 2-10 - 烯基或芳基，其中C 1-20 - 烷基可以是未取代的或被一个或多个 C 3-8 - 环烷基，C 2-10 - 烯基，苯基，卤素，OR 11，NR 12 R 13，SR 14，SO 3 H或COOR 15，芳基可以是未被取代的或被一个或多个卤素取代，C 1-10烷基，卤代C 1-10 - 烷基，C 3-8 - 环烷基C2-10 - 烯基，苯基，OR11，NR12R13，SR14，SO3H或COOR15，其中 在R 11，R 12，R 13，R 14和R 15可以相同或不同，可以是氢，C 1-10 - 烷基，C 3-8 - 环烷基或C 2-10 - 烯基，一种制备这些组合物的方法， 涂覆这些组合物的基材，用这些组合物涂布的基材，使用这些组合物制备标记的基材的方法，通过后一方法获得的标记的底物和某些显色剂。

公开(公告)号：US07893292B2

公开(公告)日：2011-02-22

申请号：US12378566

申请日：2009-02-17

申请人： Barbara Wagner ,  Thomas Ehlis ,  Stefan Müller

发明人： Barbara Wagner ,  Thomas Ehlis ,  Stefan Müller

IPC分类号： C07C255/00 ,  A61K8/00 ,  A61K8/18 ,  A61K8/49 ,  A61K31/13 ,  A61K31/16 ,  A61Q17/04 ,  A01N33/00 ,  A01N33/02

CPC分类号： C07D295/116 ,  A61K8/41 ,  A61K8/44 ,  A61K8/46 ,  A61K8/494 ,  A61K8/81 ,  A61Q17/00 ,  A61Q17/02 ,  C07C225/20 ,  C07C229/46 ,  C07C255/31 ,  C07C317/48 ,  C07C2601/14 ,  C07C2601/16 ,  C07D295/155

摘要： Described are merocyanine derivatives of formula wherein R2 is hydrogen; C1-C22alkyl; cyclo-C3-C8alkyl; unsubstituted or C1-C6alkyl- or C1-C6alkoxy-substituted C6-C20aryl; a cyano group; or R1 and R2 together with the nitrogen atom linking them form a —(CH2)m— ring which is optionally interrupted by —O— or by —NR7—; R4 is a cyano group; or -Q1-R5; Q1 is —COO—; —CONH—; —CO—; —SO2—; or —CONR6—; R5 is C1-C22alkyl; cyclo-C3-C8alkyl; or unsubstituted or C1-C6alkyl-substituted C6-C20aryl; R6 is hydrogen; C1-C22alkyl; cyclo-C3-C8alkyl; unsubstituted or C1-C6alkyl- or C1-C6alkoxy-substituted C6-C20aryl; R7 is hydrogen; C1-C22alkyl; cyclo-C3-C8alkyl; unsubstituted or C1-C6alkyl- or C1-C6alkoxy-substituted C6-C20aryl; the cyclohexene radical C is not substituted or substituted by one or more C1-C5alkyl; m is from 3 to 7; n is from 2 to 4; and o is from 2 to 4. Said merocyanine derivatives are useful in protecting human and animal hair and skin from UV radiation and to cosmetic compositions comprising said derivatives.

摘要翻译： 描述的是下式的部花青衍生物其中R2是氢; C 1 -C 22烷基; 环-C 3 -C 8烷基; 未取代的或C 1 -C 6烷基 - 或C 1 -C 6烷氧基取代的C 6 -C 20芳基; 氰基; 或R 1和R 2与连接它们的氮原子一起形成 - （CH 2）m - 环，其任选被-O-或-NR 7 - 间隔; R4是氰基; 或-Q1-R5; Q1是-COO-; -CONH-; -CO-; -SO2-; 或-CONR6-; R5是C1-C22烷基; 环C 3 -C 8烷基; 或未取代的或C 1 -C 6烷基取代的C 6 -C 20芳基; R6是氢; C 1 -C 22烷基; 环-C 3 -C 8烷基; 未取代的或C 1 -C 6烷基 - 或C 1 -C 6烷氧基取代的C 6 -C 20芳基; R7是氢; C 1 -C 22烷基; 环-C 3 -C 8烷基; 未取代的或C 1 -C 6烷基 - 或C 1 -C 6烷氧基取代的C 6 -C 20芳基; 环己烯基C不被一个或多个C 1 -C 5烷基取代或取代; m为3〜7; n为2〜4; 和o为2至4.所述的部花青衍生物可用于保护人和动物毛发和皮肤免受紫外线辐射和包含所述衍生物的化妆品组合物。

公开(公告)号：US20090060853A1

公开(公告)日：2009-03-05

申请号：US12284044

申请日：2008-09-18

申请人： Barbara Wagner ,  Thomas Ehlis ,  Sebastien Mongiat ,  Kai Eichin

发明人： Barbara Wagner ,  Thomas Ehlis ,  Sebastien Mongiat ,  Kai Eichin

IPC分类号： A61K8/49 ,  C07D277/62 ,  C07D417/10 ,  A61Q17/04

CPC分类号： A61K8/49 ,  A61K8/893 ,  A61K8/894 ,  A61Q17/04 ,  C07D277/66

摘要： The Use, as a UV filter, of a compound of formula R1 and R2 are each independently of the other hydrogen; unsubstituted or halo-, amino-, mono- or di-C1-C5alkylamino-, cyano- or C1-C5alkoxy-substituted C1-C22alkyl, C5-C10cycloalkyl, carboxy-C1-C22alkyl, carboxy-C6-C10aryl, C6-C10aryl, C6-C10aryl-C1-C5alkyl; carbamoyl; or sulfamoyl; or R1 and R2, together with the nitrogen atom linking them, form a 5- to 7-membered heterocyclic radical; and R3 is hydrogen; or C1-C22alkyl; and R4 is hydrogen; hydroxy; C1-C22alkyl; or C1-C22alkoxy; is described. The compounds of formula (1) are suitable especially as UV filters in cosmetic preparations.

公开(公告)号：US20080081908A1

公开(公告)日：2008-04-03

申请号：US11901660

申请日：2007-09-18

申请人： Gunther Schlingloff ,  Torsten Wieprecht ,  Uwe Heinz ,  Albert Schneider ,  Marie-Josee Dubs ,  Frank Bachmann ,  Menno Hazenkamp ,  Thomas Ehlis ,  Cornelia Vincenzi ,  Josef Dannacher

发明人： Gunther Schlingloff ,  Torsten Wieprecht ,  Uwe Heinz ,  Albert Schneider ,  Marie-Josee Dubs ,  Frank Bachmann ,  Menno Hazenkamp ,  Thomas Ehlis ,  Cornelia Vincenzi ,  Josef Dannacher

IPC分类号： C07D403/14

CPC分类号： C07D401/14 ,  C11D3/168 ,  C11D3/3932

摘要： Use of metal complex compounds of formula (1) and/or (1′) [LnMemXp]zYq  (1), [L′nMemXp]zYq  (1′), wherein all substituents are as defined in the claims, as catalysts for oxidation reactions, and also novel metal complex compounds and novel ligands.

摘要翻译： 使用式（1）和/或（1'）的金属络合物化合物<？in-line-formula description =“In-line Formulas”end =“lead”？> [L> n （1），＆lt;＆lt;行内公式描述=“In” -line公式“end =”tail“？> <？in-line-formula description =”In-line Formulas“end =”lead“？> [L' （1'），<？in-line-formula description =“在线公式” 其中所有取代基如权利要求中所定义，作为用于氧化反应的催化剂，以及新型金属络合物和新型配体。

公开(公告)号：US20080075746A1

公开(公告)日：2008-03-27

申请号：US11632686

申请日：2005-07-11

申请人： Stefan Muller ,  Thomas Ehlis ,  Jochen Giesinger ,  Gilbert Kreyer

发明人： Stefan Muller ,  Thomas Ehlis ,  Jochen Giesinger ,  Gilbert Kreyer

IPC分类号： A61K8/02 ,  A61K8/00 ,  A61Q17/04

CPC分类号： A61Q17/04 ,  A61K8/02 ,  A61K9/107 ,  A61K2800/412

摘要： Disclosed is the use of an insoluble or sparingly soluble micronized substance class which is not a cosmetic UV absorber and which is dispersed in the oil- or water-phase of a cosmetic or dermatological composition for the enhancement of light protecting action of this cosmetic or dermatological composition comprising at least one cosmetic UV filter which is soluble in the water- or oil-phase. The cosmetic preparation according to the invention shows a remarkable increase in SPF.

摘要翻译： 公开了使用不是化妆品UV吸收剂并且分散在化妆品或皮肤病学组合物的油相或水相中的不溶性或微溶的微粉化物质类，以增强该化妆品或皮肤病学的光保护作用 组合物，其包含至少一种可溶于水相或油相的化妆品UV过滤器。 根据本发明的化妆品显示出SPF的显着增加。