公开(公告)号：US20130040858A1

公开(公告)日：2013-02-14

申请号：US13483157

申请日：2012-05-30

申请人： Scott Tomlins ,  Daniel Rhodes ,  Arul Chinnaiyan ,  Rohit Mehra ,  Mark A. Rubin ,  Xiao-Wei Sun ,  Sven Perner ,  Charles Lee ,  Francesca Demichelis

发明人： Scott Tomlins ,  Daniel Rhodes ,  Arul Chinnaiyan ,  Rohit Mehra ,  Mark A. Rubin ,  Xiao-Wei Sun ,  Sven Perner ,  Charles Lee ,  Francesca Demichelis

IPC分类号： C40B40/06 ,  C07H21/04

CPC分类号： C12Q1/6886 ,  A01K67/0275 ,  A01K2217/072 ,  A01K2217/206 ,  A01K2227/105 ,  A01K2267/0331 ,  C07K14/82 ,  C07K2319/00 ,  C12N9/6424 ,  C12N9/6445 ,  C12N15/113 ,  C12N2310/11 ,  C12N2310/14 ,  C12Q2600/106 ,  C12Q2600/112 ,  C12Q2600/118 ,  C12Q2600/136 ,  C12Q2600/156 ,  C12Q2600/158 ,  G01N33/57434 ,  Y10S435/81

摘要： Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.

摘要翻译： 描述了前列腺癌中雄激素调节基因和ETS家族成员基因的复发基因融合。 还提供了在前列腺癌诊断，研究和治疗中具有效用的组合物和方法。

公开(公告)号：US20120218124A1

公开(公告)日：2012-08-30

申请号：US13035514

申请日：2011-02-25

申请人： Charles Lee ,  Jaime Camhi ,  Annie Lien ,  Marco Lobato

发明人： Charles Lee ,  Jaime Camhi ,  Annie Lien ,  Marco Lobato

IPC分类号： G08G1/00

CPC分类号： B60W30/18163 ,  B60W30/143 ,  B60W40/04 ,  B60W50/14 ,  B60W2550/30 ,  B60W2720/10 ,  B60W2720/106

摘要： A method for assisting a driver driving a vehicle, and a driver assistance system for assisting a driver driving a vehicle are described.

摘要翻译： 描述了一种用于辅助驾驶车辆的驾驶员的方法和用于辅助驾驶车辆的驾驶员的驾驶员辅助系统。

公开(公告)号：US08239674B2

公开(公告)日：2012-08-07

申请号：US11821165

申请日：2007-06-22

申请人： Charles Lee ,  David N. Hall, Jr.

发明人： Charles Lee ,  David N. Hall, Jr.

IPC分类号： G06F21/00

CPC分类号： G06F21/6218 ,  G06F2221/2147

摘要： According to one embodiment of the invention, a method comprises receiving a write request for a file. A temporary file associated with the file is created in response to the write request. A write-lock is applied to the temporary file, namely the file includes a setting that restricts write access to only a component that created or opens the temporary file. Thereafter, the temporary file is closed to disable the write-lock and to enable a component that initiated the write request to access the temporary file.

摘要翻译： 根据本发明的一个实施例，一种方法包括接收对文件的写入请求。 与该文件相关联的临时文件是响应写请求而创建的。 对临时文件应用写锁定，即该文件包括限制仅对创建或打开临时文件的组件的写访问权限的设置。 此后，临时文件关闭以禁用写锁定，并使启动写请求的组件能够访问临时文件。

公开(公告)号：US08199006B2

公开(公告)日：2012-06-12

申请号：US11948934

申请日：2007-11-30

申请人： Eric Liu ,  Sagar Savant ,  Peter Sobczak ,  Charles Lee ,  Peter Skillman

发明人： Eric Liu ,  Sagar Savant ,  Peter Sobczak ,  Charles Lee ,  Peter Skillman

IPC分类号： G08B1/08 ,  G08B21/00

CPC分类号： G06F1/3203 ,  G06F1/1626 ,  G06F1/3231 ,  H04M1/72563 ,  H04M2250/12 ,  H04M2250/22 ,  Y02D10/173

摘要： A computing device is configured to make a determination as to whether a device is being held in a hand. In response to determining that the device is being held, the device transitions itself, or one or more of its hardware or software component, into a particular state of operation.

摘要翻译： 计算设备被配置为确定设备是否被握在手中。 响应于确定设备被保持，设备将其自身或其硬件或软件组件中的一个或多个转换为特定操作状态。

公开(公告)号：US08035023B2

公开(公告)日：2011-10-11

申请号：US12546913

申请日：2009-08-25

申请人： Marcial Hernandez ,  Arne Stoschek ,  Jason Swager ,  Charles Lee

发明人： Marcial Hernandez ,  Arne Stoschek ,  Jason Swager ,  Charles Lee

IPC分类号： G10H1/00 ,  G10H1/18

CPC分类号： G06F17/30755

摘要： An entertainment system has a music storage system storing a plurality of music pieces, a playback system coupled with the music storage system, a navigation system providing current map information including a present location, wherein a current map has a plurality of zones each being assigned to one of a plurality of zone types, and a controller for controlling playback of selected music pieces, wherein the controller maintains a plurality of playlists, each having a plurality of music pieces and being assigned to at least one zone type. The controller receives information of a present location and a current zone type and selects an assigned playlist, wherein the navigation system further provides information about a distance and/or time to a next zone. The controller modifies the assigned playlist such that a transition to the next zone is timely synchronized with the ending of a music piece of the assigned playlist.

摘要翻译： 娱乐系统具有存储多个乐曲的音乐存储系统，与音乐存储系统耦合的回放系统，提供包括当前位置的当前地图信息的导航系统，其中当前地图具有多个区域，每个区域被分配到 多个区域类型中的一个，以及用于控制所选音乐片段的重放的控制器，其中控制器保持多个播放列表，每个播放列表具有多个音乐片段并被分配至少一个区域类型。 控制器接收当前位置和当前区域类型的信息，并选择分配的播放列表，其中导航系统进一步向下一个区域提供关于距离和/或时间的信息。 控制器修改分配的播放列表，使得到下一个区域的转换与分配的播放列表的乐曲的结束及时同步。

公开(公告)号：US20110110923A1

公开(公告)日：2011-05-12

申请号：US12867336

申请日：2009-02-12

申请人： Charles Lee ,  Carly Murphy ,  Pasi Janne

发明人： Charles Lee ,  Carly Murphy ,  Pasi Janne

IPC分类号： A61K39/395 ,  C12Q1/68 ,  A61K38/00 ,  A61P35/00 ,  A61K31/7088 ,  C07H21/04

CPC分类号： C12Q1/6886 ,  C12Q1/6841 ,  C12Q2600/106 ,  C12Q2600/112 ,  C12Q2600/156 ,  G01N33/533 ,  G01N33/582 ,  C12Q2565/102

摘要： Methods and compositions provided relate to conducting a FISH assay for detecting a chromosomal inversion between EML4 and ALK. The FISH assay described herein is useful for diagnostic and prognostic purposes, as well as for determination of therapeutic strategies.

摘要翻译： 提供的方法和组合涉及进行FISH测定以检测EML4和ALK之间的染色体反转。 本文描述的FISH测定法可用于诊断和预后目的以及用于确定治疗策略。

公开(公告)号：US20070099390A1

公开(公告)日：2007-05-03

申请号：US11263419

申请日：2005-10-31

申请人： Charles Lee ,  Chi-Hsi Wu

发明人： Charles Lee ,  Chi-Hsi Wu

IPC分类号： H01L21/20

CPC分类号： H01L28/91 ,  H01L27/10852 ,  H01L28/55

摘要： A method of fabricating a vertical MIM capacitor. An insulation layer is formed on the substrate. The insulation layer is patterned to form an opening in a predetermined area of a core electrode. Then, the opening is filled to form a sacrificial plug. Subsequently, the insulation layer is patterned to form a trench in a predetermined area of an outer electrode around the sacrificial plug. A fenced insulation layer is formed around the sacrificial plug simultaneously. After the sacrificial plug is removed, a metal layer is filled in the predetermined area of the core and outer electrodes. A vertical MIM capacitor comprising the core electrode, the fenced insulation layer, and the outer electrode is finally formed. The invention also provides a vertical MIM capacitor.

摘要翻译： 一种制造垂直MIM电容器的方法。 在基板上形成绝缘层。 将绝缘层图案化以在芯电极的预定区域中形成开口。 然后，填充开口以形成牺牲塞。 随后，将绝缘层图案化以在牺牲插塞周围的外部电极的预定区域中形成沟槽。 围绕牺牲塞同时形成围栏绝缘层。 在去除牺牲塞之后，在芯和外电极的预定区域中填充金属层。 最终形成包括芯电极，围栏绝缘层和外电极的垂直MIM电容器。 本发明还提供一种垂直MIM电容器。

公开(公告)号：US20070037319A1

公开(公告)日：2007-02-15

申请号：US11501913

申请日：2006-08-10

申请人： Kai Chan ,  Charles Lee ,  Gerald Ofner

发明人： Kai Chan ,  Charles Lee ,  Gerald Ofner

IPC分类号： H01L21/00

CPC分类号： H01L21/6835 ,  H01L21/563 ,  H01L21/6836 ,  H01L23/3157 ,  H01L24/11 ,  H01L24/12 ,  H01L24/16 ,  H01L24/27 ,  H01L24/94 ,  H01L2221/68327 ,  H01L2224/05571 ,  H01L2224/05573 ,  H01L2224/11003 ,  H01L2224/11822 ,  H01L2224/13099 ,  H01L2224/16225 ,  H01L2224/274 ,  H01L2224/32225 ,  H01L2224/73204 ,  H01L2224/81011 ,  H01L2924/00014 ,  H01L2924/01005 ,  H01L2924/01006 ,  H01L2924/01013 ,  H01L2924/01015 ,  H01L2924/01033 ,  H01L2924/01078 ,  H01L2924/01082 ,  H01L2924/01322 ,  H01L2924/014 ,  H01L2924/15311 ,  H01L2924/00 ,  H01L2224/05599

摘要： A semiconductor package comprises a substrate which includes a plurality of conducting traces and upper contact areas on its upper surface and a second plurality of lower conductive traces and external contact areas on its bottom surface and external conducting members attached to the external contact areas. The semiconductor package also includes a semiconductor die comprising an active surface with a plurality of die contact pads, electrically connected to the contact areas of the substrate by conducting members. A support layer between the conducting members on the active surface of the semiconductor die covers at least the base portion of the conducting members. A method relates to the production of the semiconductor package.

摘要翻译： 半导体封装包括：衬底，其包括多个导电迹线和其上表面上的上接触区域，以及在其底表面上的第二多个下导电迹线和外部接触区域以及附接到外部接触区域的外部导电构件。 半导体封装还包括半导体管芯，其包括具有多个管芯接触焊盘的有源表面，其通过导电构件电连接到衬底的接触区域。 半导体管芯的有源表面上的导电构件之间的支撑层至少覆盖导电构件的基部。 一种方法涉及半导体封装的制造。

公开(公告)号：US20060051286A1

公开(公告)日：2006-03-09

申请号：US10543241

申请日：2003-11-10

申请人： Philip Baldwin ,  Norman Murray ,  Charles Lee ,  Michael Farrall

发明人： Philip Baldwin ,  Norman Murray ,  Charles Lee ,  Michael Farrall

IPC分类号： C01F11/46

CPC分类号： C02F1/5236 ,  C01F7/066 ,  C02F1/66

摘要： A method of treating hydroxide alkaline waste and by-products to render the material neutralized or reduced in pH from near 14 to a minimum lower limit of about 5.3 based on aluminum poly cation salts, rendering the waste or by-product stream suitable for ultimate disposal or reuse. The method comprises contacting together a mixture of moderate to high alkaline waste or by-product material with a pH in the range of 7.5-14, with sufficient water added or found within the alkaline material, with one or more poly cationic salts in the dry form taken from a group of salts containing tri-valent aluminum, tri-valent iron, di-valent calcium, di-valent magnesium, di-valent manganese, di-valent zinc, or any polyvalent cationic salt that is soluble in water to a minimum extent of 0.5 grams per 100 milliliters of water at near 0° Centigrade and 2 grams per 100 milliliters of water at near 100° Centigrade, in such a way to cause these materials to interact in a double replacement reaction to form a soluble salt reaction by-product and an insoluble hydroxide precipitate with water solubility characteristics, between 0° Centigrade and 100° Centigrade, equal to or exceeding that of CaS04*2H2O (gypsum) or approximately 0.20 grams per 100 milliliters of water. The added salts) may be dry or made up of a brine or dilute salt solution of the chosen salt or salts from the set of poly cation salts suitable to reduce hydroxide alkalinity in waste and by-product materials causing the pH to drop immediately upon thorough mixing of the poly cation salts and the waste/product materials, resulting in a treated waste/by-product stream/that is suitable for ultimate disposal or re-use.

摘要翻译： 一种处理氢氧化物碱性废物和副产物的方法，使物质基于铝聚阳离子盐将pH中和或降低至近乎14至最低下限约5.3，使得废物或副产物流适合于最终处置 或重用。 该方法包括将中等至高碱性废物或副产物材料的混合物与7.5-14的pH值混合在一起，在碱性物质中加入足够的水或发现碱性物质中的一种或多种聚阳离子盐 从含有三价铝，三价铁，二价钙，二价镁，二价锰，二价锌或任何可溶于水的多价阳离子盐的盐组成的一组盐 在接近0摄氏度时每100毫升水中0.5克的最小程度和接近100摄氏度的每100毫升水2克，使得这些物质在双重置换反应中相互作用形成可溶性盐反应 副产物和具有水溶性特征的不溶性氢氧化物沉淀物，在0摄氏度和100摄氏度之间，等于或超过CaSO 4·2H 2 O（石膏）或约0.20克/ 100毫升水。 添加的盐）可以是干的，或者由选自所选择的盐或盐的盐水或稀盐盐组成，所述盐或多种盐适用于减少废物中的氢氧化物碱性和副产物，导致pH在彻底下降后立即下降 混合聚阳离子盐和废物/产品材料，产生经处理的废物/副产物流/适用于最终处置或再利用。

公开(公告)号：US20050182881A1

公开(公告)日：2005-08-18

申请号：US10708634

申请日：2004-03-16

申请人： Horng-Yee Chou ,  Szu-Kuang Chou ,  Charles Lee

发明人： Horng-Yee Chou ,  Szu-Kuang Chou ,  Charles Lee

IPC分类号： G06F12/00 ,  G06F13/00 ,  G06F13/38 ,  H01R33/00

CPC分类号： G06F13/385 ,  G06K19/07732 ,  G06K19/07733 ,  H01R13/26

摘要： An extended Secure-Digital (SD) card has a second interface that uses some of the SD-interface lines. The SD card's mechanical and electrical card-interface is used, but 2 or 4 signals in the SD interface are multiplexed for use by the second interface. The second interface can have a single differential pair of serial-data lines to perform Universal-Serial-Bus (USB) transfers, or two pairs of differential data lines for Serial-Advanced-Technology-Attachment (SATA), Peripheral Component Interconnect Express (PCIE), or IEEE 1394 transfers. A card-detection routine on a host can initially use the SD interface to detect extended capabilities and command the card to switch to using the second interface. The extended SD card can communicate with legacy SD hosts using just the SD interface, and extended SD hosts can read legacy SD cards using just the SD interface, or extended SD cards using the second interface. MultiMediaCard and Memory Stick are alternatives.

摘要翻译： 扩展的安全数字（SD）卡具有使用一些SD接口线路的第二接口。 使用SD卡的机电卡接口，SD接口中的2或4个信号被复用以供第二个接口使用。 第二个接口可以具有单个差分对的串行数据线来执行通用串行总线（USB）传输，或两对差分数据线用于串行高级技术附件（SATA），外围组件互连Express（Express） PCIE）或IEEE 1394传输。 主机上的卡检测程序最初可以使用SD接口来检测扩展功能，并命令卡切换到使用第二个接口。 扩展SD卡可以使用SD接口与传统SD主机进行通信，扩展SD主机可以使用SD接口读取旧SD卡，也可以使用第二个接口读取扩展SD卡。 多媒体卡和记忆棒是替代品。